Structure and Function of Embryonic Rat Retinal Sheet Transplants

REFERENCES

• Algvere P V, Berglin L, Gouras P, Sheng Y, Kopp E D. Transplantation of RPE in age-related macular degeneration: observations in disciform lesions and dry RPE atrophy. Graefes Archi Clin Exp Ophthalmol 1997; 235: 149–158
   PubMed Web of Science ®Google Scholar
• Juliusson B, Bergström A, van Veen T, Ehinger B. Cellular organization in retinal transplants using cell suspensions or fragments of embryonic retinal tissue. Cell Transplant 1993; 2: 411–418
   PubMed Web of Science ®Google Scholar
• Li L, Turner J E. Optimal conditions for long-term photoreceptor cell rescue in RCS rats: the necessity for healthy RPE transplants. Exp Eye Res 1991; 52: 669–679
   PubMed Web of Science ®Google Scholar
• Aramant R B, Seiler M J, Ehinger B, Bergström A, Adolph A R, Turner J E. Neuronal markers in rat retinal grafts. Dev. Brain Res. 1990; 53: 47–61
   PubMedGoogle Scholar
• Del Cerro M, Ison J R, Bowen G P, Lazar E, Del Cerro C. Intraretinal grafting restores function in light-blinded rats. NeuroReport 1991; 2: 529–532
   PubMed Web of Science ®Google Scholar
• Gouras P, Du J, Kjeldbye H, Yamamoto S, Zack D J. Long-term photoreceptor transplants in dystrophic and normal mouse retina. Invest Ophthalmol Vis Sci. 1994; 35: 3145–3153
   PubMedGoogle Scholar
• Kwan A S, Wang S, Lund R D. Photoreceptor layer reconstruction in a rodent model of retinal degeneration. Exp Neurol 1999; 159: 21–33
   PubMedGoogle Scholar
• Seiler M, Aramant R. Transplantation of embryonic retinal donor cells labelled with BrdU or carrying a genetic marker to adult retina. Exp Brain Res. 1995; 105: 59–66
   PubMedGoogle Scholar
• Berger A S, Tezel T H, Del Priore L V, Kaplan H J. Photoreceptor transplantation in retinitis pigmentosa: short-term follow-up. Ophthalmology 2003; 110: 383–391
   PubMed Web of Science ®Google Scholar
• Kaplan H J, Tezel T H, Berger A S, Wolf M L, Del Priore L V. Human photoreceptor transplantation in retinitis pigmentosa. A safety study. Arch Ophthalmol 1997; 115: 1168–1172
   PubMed Web of Science ®Google Scholar
• Silverman M S, Hughes S E, Valentino T, Liu Y. Photoreceptor transplantation: Anatomic, electrophysiologic, and behavioral evidence for the functional reconstruction of retinas lacking photoreceptors. Exp Neurol. 1992; 115: 87–94
   PubMed Web of Science ®Google Scholar
• Ghosh F, Wong F, Johansson K, Bruun A, Petters R M. Transplantation of full-thickness retina in the rhodopsin transgenic pig. Retina 2004; 24: 98–109
   PubMed Web of Science ®Google Scholar
• Sagdullaev B T, Aramant R B, Seiler M J, Woch G, McCall M A. Retinal transplantation-induced recovery of retinotectal visual function in a rodent model of retinitis pigmentosa. Invest Ophthalmol Vis Sci 2003; 44: 1686–1695
   PubMed Web of Science ®Google Scholar
• Seiler M J, Aramant R B. Intact sheets of fetal retina transplanted to restore damaged rat retinas. Invest Ophthalmol Vis Sci 1998; 39: 2121–2131
   PubMed Web of Science ®Google Scholar
• Seiler M J, Aramant R B. Transplantation of neuroblastic progenitor cells as a sheet preserves and restores retinal function. Semin Ophthalmol 2005; 20: 31–42
   PubMedGoogle Scholar
• Ali R R. Prospects for gene therapy. Novartis Found Symp 2004; 255: 165–72, discussion 173–178
   PubMedGoogle Scholar
• Dejneka N S, Rex T S, Bennett J. Gene therapy and animal models for retinal disease. Dev Ophthalmol 2003; 37: 188–198
   PubMedGoogle Scholar
• Delyfer M N, Leveillard T, Mohand-Said S, Hicks D, Picaud S, Sahel J A. Inherited retinal degenerations: therapeutic prospects. Biol Cell 2004; 96: 261–269
   PubMed Web of Science ®Google Scholar
• Loewenstein J I, Montezuma S R, Rizzo J F. 3rd Outer retinal degeneration: an electronic retinal prosthesis as a treatment strategy. Arch Ophthalmol 2004; 122: 587–596
   PubMedGoogle Scholar
• Margalit E, Maia M, Weiland J D, et al. Retinal prosthesis for the blind. Surv Ophthalmol 2002; 47: 335–356
   PubMed Web of Science ®Google Scholar
• Rizzo J F, 3rd, Wyatt J, Humayun M, et al. Retinal prosthesis: an encouraging first decade with major challenges ahead. Ophthalmology 2001; 108: 13–14
   PubMed Web of Science ®Google Scholar
• Weiland J D, Liu W, Humayun M S. Retinal prosthesis. Annu Rev Biomed Eng 2005; 7: 361–401
   PubMed Web of Science ®Google Scholar
• Caffe A R, Soderpalm A K, Holmqvist I, van Veen T. A combination of CNTF and BDNF rescues rd photoreceptors but changes rod differentiation in the presence of RPE in retinal explants. Invest Ophthalmol Vis Sci 2001; 42: 275–282
   PubMedGoogle Scholar
• Chong N H, Bird A C. Management of inherited outer retinal dystrophies: present and future. Br J Ophthalmol 1999; 83: 120–122
   PubMedGoogle Scholar
• Sauvé Y, Girman S V, Wang S, Lawrence J M, Lund R D. Progressive visual sensitivity loss in the Royal College of Surgeons rat: perimetric study in the superior colliculus. Neuroscience 2001; 103: 51–63
   PubMedGoogle Scholar
• Thomas B B, Aramant R B, Sadda S R, Seiler M J. Retinal transplantation-a treatment strategy for retinal degenerative diseases. Retinal Degenerative Diseases, J G Hollyfield, R E Anderson, M M La Vail. Springer, New York 2006; 367–376
   Google Scholar
• Thomas B B, Seiler M J, Sadda S R, Aramant R B. Superior colliculus responses to light-preserved by transplantation in a slow degeneration rat model. Exp Eye Res 2004; 79: 29–39
   PubMed Web of Science ®Google Scholar
• Algvere P V, Gouras P, Dafgard Kopp E. Long-term outcome of RPE allografts in non-immunosuppressed patients with AMD. Eur J Ophthalmol 1999; 9: 217–230
   PubMed Web of Science ®Google Scholar
• Das T, del Cerro M, Jalali S, et al. The transplantation of human fetal neuroretinal cells in advanced retinitis pigmentosa patients: results of a long-term safety study. Exp Neurol 1999; 157: 58–68
   PubMed Web of Science ®Google Scholar
• Radtke N D, Aramant R B, Seiler M J, Petry H M, Pidwell D J. Vision change after sheet transplant of fetal retina with RPE to a retinitis pigmentosa patient. Arch Ophthalmol 2004; 122: 1159–1165
   PubMedGoogle Scholar
• Radtke N D, Seiler M J, Aramant R B, Petry H M, Pidwell D J. Transplantation of intact sheets of fetal neural retina with its retinal pigment epithelium in retinitis pigmentosa patients. Am J Ophthalmol 2002; 133: 544–550
   PubMed Web of Science ®Google Scholar
• Aramant R B, Seiler M J, Ball S L. Successful cotransplantation of intact sheets of fetal retinal pigment epithelium with retina. Invest Ophthalmol Vis Sci 1999; 40: 1557–1564
   PubMed Web of Science ®Google Scholar
• Seiler M J, Aramant R B, Ball S L. Photoreceptor function of retinal transplants implicated by light-dark shift of S-antigen and rod transducin. Vision Res 1999; 39: 2589–2596
   PubMed Web of Science ®Google Scholar
• Arai S, Thomas B B, Seiler M J, et al. Restoration of visual responses following transplantation of intact retinal sheets in rd mice. Exp Eye Res 2004; 79: 331–341
   PubMed Web of Science ®Google Scholar
• Woch G, Aramant R B, Seiler M J, Sagdullaev B T, McCall M A. Retinal transplants restore visually evoked responses in rats with photoreceptor degeneration. Invest Ophthalmol Vis Sci 2001; 42: 1669–1676
   PubMed Web of Science ®Google Scholar
• Kisseberth W C, Brettingen N T, Lohse J K, Sandgren E P. Ubiquitous expression of marker transgenes in mice and rats. Dev Biol 1999; 214: 128–138
   PubMed Web of Science ®Google Scholar
• Mujtaba T, Han S S, Fischer I, Sandgren E P, Rao M S. Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Exp Neurol 2002; 174: 48–57
   PubMed Web of Science ®Google Scholar
• Aramant R B, Seiler M J. Retinal transplantation-advantages of intact fetal sheets. Prog Retin Eye Res 2002a; 21: 57–73
   PubMed Web of Science ®Google Scholar
• Thomas B B, Aramant R B, Sadda S R, Seiler M J. Light response differences in the superior colliculus of albino and pigmented rats. Neurosci Lett 2005; 385: 143–147
   PubMedGoogle Scholar
• Eldred W D, Zucker C, Karten H J, Yazulla S. Comparison of fixation and penetration enhancement techniques for use in ultrastructural immunocytochemistry. J Histochem Cytochem 1983; 31: 285–292
   PubMed Web of Science ®Google Scholar
• Seiler M J, Sagdullaev B T, Woch G, Thomas B B, Aramant R B. Transsynaptic virus tracing from host brain to subretinal transplants. Eur J Neurosci 2005; 21: 161–172
   PubMed Web of Science ®Google Scholar
• Fintz A C, Audo I, Hicks D, Mohand-Said S, Leveillard T, Sahel J. Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration. Invest Ophthalmol Vis Sci 2003; 44: 818–825
   PubMed Web of Science ®Google Scholar
• Mohand-Said S, Hicks D, Dreyfus H, Sahel J A. Selective transplantation of rods delays cone loss in a retinitis pigmentosa model. Arch Ophthalmol 2000; 118: 807–811
   PubMedGoogle Scholar
• Ghosh F, Bruun A, Ehinger B. Graft-host connections in long-term full-thickness embryonic rabbit retinal transplants. Invest Ophthalmol Vis Sci 1999a; 40: 126–132
   PubMed Web of Science ®Google Scholar
• Aramant R B, Seiler M J. Transplanted sheets of human retina and retinal pigment epithelium develop normally in nude rats. Exp Eye Res 2002b; 75: 115–125
   PubMed Web of Science ®Google Scholar
• Ghosh F, Johansson K, Ehinger B. Long-term full-thickness embryonic rabbit retinal transplants. Invest Ophthalmol Vis Sci 1999b; 40: 133–142
   PubMedGoogle Scholar
• Aramant R B, Seiler M J. Progress in retinal sheet transplantation. Prog Retin Eye Res 2004; 23: 475–494
   PubMed Web of Science ®Google Scholar
• Aramant R B, Seiler M J. Human embryonic retinal cell transplants in athymic immunodeficient rat hosts. Cell Transplant 1994; 3: 461–474
   PubMed Web of Science ®Google Scholar
• Ehinger B, Bergström A, Seiler M, et al. Ultrastructure of human retinal cell transplants with long survival times in rats. Exp. Eye Res. 1991; 53: 447–460
   PubMed Web of Science ®Google Scholar
• Gouras P, Tanabe T. Survival and integration of neural retinal transplants in rd mice. Graefes Arch Clin Exp Ophthalmol 2003; 241: 403–409
   PubMedGoogle Scholar
• Guo Y, Saloupis P, Shaw S J, Rickman D W. Engraftment of adult neural progenitor cells transplanted to rat retina injured by transient ischemia. Invest Ophthalmol Vis Sci 2003; 44: 3194–3201
   PubMed Web of Science ®Google Scholar
• Lai C C, Gouras P, Doi K, et al. Tracking RPE transplants labeled by retroviral gene transfer with green fluorescent protein. Invest Ophthalmol Vis Sci 1999; 40: 2141–2146
   PubMedGoogle Scholar
• Mizumoto H, Mizumoto K, Shatos M A, Klassen H, Young M J. Retinal transplantation of neural progenitor cells derived from the brain of GFP transgenic mice. Vision Res 2003; 43: 1699–1708
   PubMed Web of Science ®Google Scholar