362
Views
2
CrossRef citations to date
0
Altmetric
Glaucoma

Structural Characterization of Glaucoma Patients with Low Ocular Blood Flow

, , , , , , , , , , & show all
Pages 1302-1308 | Received 07 Aug 2019, Accepted 17 Feb 2020, Published online: 12 Mar 2020

References

  • Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014;311:1901–11. doi:10.1001/jama.2014.3192.
  • Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. 2014;121:2081–90. doi:10.1016/j.ophtha.2014.05.013.
  • Nakazawa T. Ocular blood flow and influencing factors for glaucoma. Asia Pac J Ophthalmol (Phila). 2016;5:38–44. doi:10.1097/APO.0000000000000183.
  • Almasieh M, Wilson AM, Morquette B, Cueva Vargas JL, Di Polo A. The molecular basis of retinal ganglion cell death in glaucoma. Prog Retin Eye Res. 2012;31:152–81. doi:10.1016/j.preteyeres.2011.11.002.
  • Leske MC. Ocular perfusion pressure and glaucoma: clinical trial and epidemiologic findings. Curr Opin Ophthalmol. 2009;20:73–78. doi:10.1097/ICU.0b013e32831eef82.
  • Marcus MW, de Vries MM, Junoy Montolio FG, Jansonius NM. Myopia as a risk factor for open-angle glaucoma: a systematic review and meta-analysis. Ophthalmology. 2011;118:1989–1994 e1982. doi:10.1016/j.ophtha.2011.03.012.
  • Nicolela MT, Drance SM. Various glaucomatous optic nerve appearances: clinical correlations. Ophthalmology. 1996;103:640–49. doi:10.1016/S0161-6420(96)30640-4.
  • Tezel G. Oxidative stress in glaucomatous neurodegeneration: mechanisms and consequences. Prog Retin Eye Res. 2006;25:490–513. doi:10.1016/j.preteyeres.2006.07.003.
  • Vohra R, Tsai JC, Kolko M. The role of inflammation in the pathogenesis of glaucoma. Surv Ophthalmol. 2013;58:311–20. doi:10.1016/j.survophthal.2012.08.010.
  • Caprioli J, Coleman AL. Blood flow in glaucoma D. Blood pressure, perfusion pressure, and glaucoma. Am J Ophthalmol. 2010;149:704–12. doi:10.1016/j.ajo.2010.01.018.
  • Wey S, Amanullah S, Spaeth GL, Ustaoglu M, Rahmatnejad K, Katz LJ. Is primary open-angle glaucoma an ocular manifestation of systemic disease? Graefes Arch Clin Exp Ophthalmol. 2019;257:665–73. doi:10.1007/s00417-019-04239-9.
  • Aizawa N, Yokoyama Y, Chiba N, Omodaka K, Yasuda M, Otomo T, Nakamura M, Fuse N, Nakazawa T. Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma. Clin Ophthalmol. 2011;5:1171–76. doi:10.2147/OPTH.S22093.
  • Takahashi H, Sugiyama T, Tokushige H, Maeno T, Nakazawa T, Ikeda T, Araie M. Comparison of CCD-equipped laser speckle flowgraphy with hydrogen gas clearance method in the measurement of optic nerve head microcirculation in rabbits. Exp Eye Res. 2013;108:10–15. doi:10.1016/j.exer.2012.12.003.
  • Shoji T, Yoshikawa Y, Kanno J, Ishii H, Ibuki H, Ozaki K, Kimura I, Shinoda K. Reproducibility of macular vessel density calculations via imaging with two different swept-source optical coherence tomography angiography systems. Transl Vis Sci Technol. 2018;7:31. doi:10.1167/tvst.7.6.31.
  • Shiga Y, Kunikata H, Aizawa N, Kiyota N, Maiya Y, Yokoyama Y, Omodaka K, Takahashi H, Yasui T, Kato K, et al. Optic nerve head blood flow, as measured by laser speckle flowgraphy, is significantly reduced in preperimetric glaucoma. Curr Eye Res. 2016;41:1447–53. doi:10.3109/02713683.2015.1127974.
  • Shiga Y, Omodaka K, Kunikata H, Ryu M, Yokoyama Y, Tsuda S, Asano T, Maekawa S, Maruyama K, Nakazawa T. Waveform analysis of ocular blood flow and the early detection of normal tension glaucoma. Invest Ophthalmol Vis Sci. 2013;54:7699–706. doi:10.1167/iovs.13-12930.
  • Shiga Y, Aizawa N, Tsuda S, Yokoyama Y, Omodaka K, Kunikata H, Yasui T, Kato K, Kurashima H, Miyamoto E, et al. Preperimetric Glaucoma Prospective Study (PPGPS): predicting visual field progression with basal optic nerve head blood flow in normotensive PPG eyes. Transl Vis Sci Technol. 2018;7:11. doi:10.1167/tvst.7.1.11.
  • Moghimi S, Zangwill LM, Penteado RC, Hasenstab K, Ghahari E, Hou H, Christopher M, Yarmohammadi A, Manalastas PIC, Shoji T, et al. Macular and optic nerve head vessel density and progressive retinal nerve fiber layer loss in glaucoma. Ophthalmology. 2018;125:1720–28. doi:10.1016/j.ophtha.2018.05.006.
  • Asano Y, Himori N, Kunikata H, Yamazaki M, Shiga Y, Omodaka K, Takahashi H, Nakazawa T. Age- and sex-dependency of the association between systemic antioxidant potential and glaucomatous damage. Sci Rep. 2017;7:8032. doi:10.1038/s41598-017-08624-4.
  • Yamazaki M, Omodaka K, Aizawa N, Nakazawa T. Estimated retinal ganglion cells counts are a valuable parameter in normal tension glaucoma. Clin Exp Ophthalmol. 2016;44:207–09. doi:10.1111/ceo.2016.44.issue-3.
  • Yokoyama Y, Tanito M, Nitta K, Katai M, Kitaoka Y, Omodaka K, Tsuda S, Nakagawa T, Nakazawa T. Stereoscopic analysis of optic nerve head parameters in primary open angle glaucoma: the glaucoma stereo analysis study. PLoS One. 2014;9:e99138. doi:10.1371/journal.pone.0099138.
  • Anderson DR. Ultrastructure of human and monkey lamina cribrosa and optic nerve head. Arch Ophthalmol. 1969;82:800–14. doi:10.1001/archopht.1969.00990020792015.
  • Lieberman MF, Maumenee AE, Green WR. Histologic studies of the vasculature of the anterior optic nerve. Am J Ophthalmol. 1976;82:405–23. doi:10.1016/0002-9394(76)90489-X.
  • Yarmohammadi A, Zangwill LM, Diniz-Filho A, Suh MH, Yousefi S, Saunders LJ, Belghith A, Manalastas PI, Medeiros FA, Weinreb RN. Relationship between optical coherence tomography angiography vessel density and severity of visual field loss in glaucoma. Ophthalmology. 2016;123:2498–508. doi:10.1016/j.ophtha.2016.08.041.
  • Kiyota N, Kunikata H, Shiga Y, Omodaka K, Nakazawa T. Ocular microcirculation measurement with laser speckle flowgraphy and optical coherence tomography angiography in glaucoma. Acta Ophthalmol. 2018;96:e485–e492. doi:10.1111/aos.2018.96.issue-4.
  • Jia Y, Wei E, Wang X, Zhang X, Morrison JC, Parikh M, Lombardi LH, Gattey DM, Armour RL, Edmunds B, et al. Optical coherence tomography angiography of optic disc perfusion in glaucoma. Ophthalmology. 2014;121:1322–32. doi:10.1016/j.ophtha.2014.01.021.
  • Meng N, Zhang P, Huang H, Ma J, Zhang Y, Li H, Qu Y. Color Doppler imaging analysis of retrobulbar blood flow velocities in primary open-angle glaucomatous eyes: a meta-analysis. PLoS One. 2013;8:e62723. doi:10.1371/journal.pone.0062723.
  • Zeitz O, Galambos P, Wagenfeld L, Wiermann A, Wlodarsch P, Praga R, Matthiessen ET, Richard G, Klemm M. Glaucoma progression is associated with decreased blood flow velocities in the short posterior ciliary artery. Br J Ophthalmol. 2006;90:1245–48. doi:10.1136/bjo.2006.093633.
  • Aizawa N, Kunikata H, Nitta F, Shiga Y, Omodaka K, Tsuda S, Nakazawa T. Age- and sex-dependency of laser speckle flowgraphy measurements of optic nerve vessel microcirculation. PLoS One. 2016;11:e0148812. doi:10.1371/journal.pone.0148812.
  • Belovay GW, Goldberg I. The thick and thin of the central corneal thickness in glaucoma. Eye (Lond). 2018;32:915–23. doi:10.1038/s41433-018-0033-3.
  • Nicolela MT, McCormick TA, Drance SM, Ferrier SN, LeBlanc RP, Chauhan BC. Visual field and optic disc progression in patients with different types of optic disc damage: a longitudinal prospective study. Ophthalmology. 2003;110:2178–84. doi:10.1016/S0161-6420(03)00801-7.
  • Omodaka K, Takada N, Yamaguchi T, Takahashi H, Araie M, Nakazawa T. Characteristic correlations of the structure-function relationship in different glaucomatous disc types. Jpn J Ophthalmol. 2015;59:223–29. doi:10.1007/s10384-015-0379-z.
  • Shin HY, Park HY, Jung Y, Choi JA, Park CK. Glaucoma diagnostic accuracy of optical coherence tomography parameters in early glaucoma with different types of optic disc damage. Ophthalmology. 2014;121:1990–97. doi:10.1016/j.ophtha.2014.04.030.
  • Hantzschel J, Terai N, Sorgenfrei F, Haustein M, Pillunat K, Pillunat LE. Morphological and functional differences between normal-tension and high-tension glaucoma. Acta Ophthalmol. 2013;91:e386–391. doi:10.1111/aos.2013.91.issue-5.
  • Chiba N, Omodaka K, Yokoyama Y, Aizawa N, Tsuda S, Yasuda M, Otomo T, Yokokura S, Fuse N, Nakazawa T. Association between optic nerve blood flow and objective examinations in glaucoma patients with generalized enlargement disc type. Clin Ophthalmol. 2011;5:1549–56. doi:10.2147/OPTH.S22097.
  • Ernest PJ, Schouten JS, Beckers HJ, Hendrikse F, Prins MH, Webers CA. An evidence-based review of prognostic factors for glaucomatous visual field progression. Ophthalmology. 2013;120:512–19. doi:10.1016/j.ophtha.2012.09.005.
  • Takada N, Omodaka K, Nakazawa T. Regional susceptibility of the optic disc to retinal nerve fiber layer thinning in different optic disc types of eyes with normal tension glaucoma. Clin Experiment Ophthalmol. 2015;43:291–93. doi:10.1111/ceo.2015.43.issue-3.
  • Omodaka K, Yabana T, Takada N, Nakazawa T. Regional correlation of macular areas and visual acuity in patients with open-angle glaucoma. Clin Experiment Ophthalmol. 2015;43:279–82. doi:10.1111/ceo.2015.43.issue-3.
  • Kiyota N, Shiga Y, Yasuda M, Aizawa N, Omodaka K, Tsuda S, Kunikata H, Nakazawa T. Sectoral differences in the association of optic nerve head blood flow and glaucomatous visual field defect severity and progression. Invest Ophthalmol Vis Sci. 2019;60:2650–58. doi:10.1167/iovs.19-27230.
  • Omodaka K, Takahashi S, Matsumoto A, Maekawa S, Kikawa T, Himori N, Takahashi H, Maruyama K, Kunikata H, Akiba M, et al. Clinical factors associated with lamina cribrosa thickness in patients with glaucoma, as measured with swept source optical coherence tomography. PLoS One. 2016;11:e0153707. doi:10.1371/journal.pone.0153707.
  • Lee EJ, Lee KM, Lee SH, Kim TW. Parapapillary choroidal microvasculature dropout in glaucoma: a comparison between optical coherence tomography angiography and indocyanine green angiography. Ophthalmology. 2017;124:1209–17. doi:10.1016/j.ophtha.2017.03.039.
  • Kiyota N, Kunikata H, Takahashi S, Shiga Y, Omodaka K, Nakazawa T. Factors associated with deep circulation in the peripapillary chorioretinal atrophy zone in normal-tension glaucoma with myopic disc. Acta Ophthalmol. 2018;96:e290–e297. doi:10.1111/aos.2018.96.issue-3.
  • Park HL, Kim JW, Park CK. Choroidal microvasculature dropout is associated with progressive retinal nerve fiber layer thinning in glaucoma with disc hemorrhage. Ophthalmology. 2018;125:1003–13. doi:10.1016/j.ophtha.2018.01.016.
  • Kwon JM, Weinreb RN, Zangwill LM, Suh MH. Parapapillary deep-layer microvasculature dropout and visual field progression in glaucoma. Am J Ophthalmol. 2019;200:65–75. doi:10.1016/j.ajo.2018.12.007.
  • Barron MJ, Griffiths P, Turnbull DM, Bates D, Nichols P. The distributions of mitochondria and sodium channels reflect the specific energy requirements and conduction properties of the human optic nerve head. Br J Ophthalmol. 2004;88:286–90. doi:10.1136/bjo.2003.027664.
  • Alexander C, Votruba M, Pesch UE, Thiselton DL, Mayer S, Moore A, Rodriguez M, Kellner U, Leo-Kottler B, Auburger G, et al. OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat Genet. 2000;26:211–15. doi:10.1038/79944.
  • Wu PC, Huang HM, Yu HJ, Fang PC, Chen CT. Epidemiology of Myopia. Asia Pac J Ophthalmol (Phila). 2016;5:386–93. doi:10.1097/APO.0000000000000236.
  • Cho HK, Kee C. Population-based glaucoma prevalence studies in Asians. Surv Ophthalmol. 2014;59:434–47. doi:10.1016/j.survophthal.2013.09.003.
  • Suzuki Y, Iwase A, Araie M, Yamamoto T, Abe H, Shirato S, Kuwayama Y, Mishima HK, Shimizu H, Tomita G, et al. Risk factors for open-angle glaucoma in a Japanese population: the Tajimi study. Ophthalmology. 2006;113:1613–17. doi:10.1016/j.ophtha.2006.03.059.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.