273
Views
8
CrossRef citations to date
0
Altmetric
Retina & Choroid

Correlation of Retinal Thickness and Swept-Source Optical Coherence Tomography Angiography Derived Vascular Changes in Patients with Neovascular Age-Related Macular Degeneration

, , , , , , , & show all
Pages 1002-1009 | Received 07 Aug 2020, Accepted 02 Nov 2020, Published online: 07 May 2021

References

  • Rosenfeld PJ. Optical coherence tomography and the development of antiangiogenic therapies in neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2016;57(9):OCT14–26. doi:10.1167/iovs.16-19969.
  • Schmidt-Erfurth U, Bogunovic H, Sadeghipour A, Schlegl T, Langs G, Gerendas BS, Osborne A, Waldstein SM. Machine learning to analyze the prognostic value of current imaging biomarkers in neovascular age-related macular degeneration. Ophthalmol Retina. 2018;2(1):24–30. doi:10.1016/j.oret.2017.03.015.
  • Zotter S, Pircher M, Torzicky T, Bonesi M, Gotzinger E, Leitgeb RA, Hitzenberger CK. Visualization of microvasculature by dual-beam phase-resolved doppler optical coherence tomography. Opt Express. 2011;19(2):1217–27. doi:10.1364/OE.19.001217.
  • Jia Y, Tan O, Tokayer J, Potsaid B, Wang Y, Liu JJ, Kraus MF, Subhash H, Fujimoto JG, Hornegger J and others. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express. 2012;20(4):4710–25. doi:10.1364/OE.20.004710.
  • Cicinelli MV, Cavalleri M, Consorte AC, Rabiolo A, Sacconi R, Bandello F, Querques G. Swept-source and spectral domain optical coherence tomography angiography versus dye angiography in the measurement of Type 1 neovascularization. Retina. 2020 Mar;40(3):499–506. doi:10.1097/IAE.0000000000002452.
  • Novais EA, Adhi M, Moult EM, Louzada RN, Cole ED, Husvogt L, Lee B, Dang S, Regatieri CV, Witkin AJ and others. Choroidal neovascularization analyzed on ultrahigh-speed swept-source optical coherence tomography angiography compared to spectral-domain optical coherence tomography angiography. Am J Ophthalmol. 2016;164:80–88. doi:10.1016/j.ajo.2016.01.011.
  • Miller AR, Roisman L, Zhang Q, Zheng F, Rafael de Oliveira Dias J, Yehoshua Z, Schaal KB, Feuer W, Gregori G, Chu Z and others. Comparison between spectral-domain and swept-source optical coherence tomography angiographic imaging of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2017;58(3):1499–505. doi:10.1167/iovs.16-20969.
  • Told R, Ginner L, Hecht A, Sacu S, Leitgeb R, Pollreisz A, Schmidt-Erfurth U. Comparative study between a spectral domain and a high-speed single-beam swept source OCTA system for identifying choroidal neovascularization in AMD. Sci Rep. 2016;6:38132. doi:10.1038/srep38132.
  • Moult E, Choi W, Waheed NK, Adhi M, Lee B, Lu CD, Jayaraman V, Potsaid B, Rosenfeld PJ, Duker JS and others. Ultrahigh-speed swept-source OCT angiography in exudative AMD. Ophthalmic Surg Lasers Imaging Retina. 2014;45(6):496–505. doi:10.3928/23258160-20141118-03.
  • Souedan V, Souied EH, Caillaux V, Miere A, Ameen AE, Blanco-Garavito R. Sensitivity and specificity of optical coherence tomography angiography (OCT-A) for detection of choroidal neovascularization in real-life practice and varying retinal expertise level. Int Ophthalmol. 2018;38(3):1051–60. doi:10.1007/s10792-017-0559-6.
  • Babiuch AS, Uchida A, Figueiredo N, Hu M, Khan M, Srivastava SK, Singh RP, Rachitskaya A, Kaiser PK, Reese JL and others. Impact of optical coherence tomography angiography review strategy on detection of choroidal neovascularization. Retina. 2019;40:672–78.
  • Faridi A, Jia Y, Gao SS, Huang D, Bhavsar KV, Wilson DJ, Sill A, Flaxel CJ, Hwang TS, Lauer AK and others. Sensitivity and specificity of OCT angiography to detect choroidal neovascularization. Ophthalmol Retina. 2017;1(4):294–303. doi:10.1016/j.oret.2017.02.007.
  • Gong J, Yu S, Gong Y, Wang F, Sun X. The diagnostic accuracy of optical coherence tomography angiography for neovascular age-related macular degeneration: A comparison with fundus fluorescein angiography. J Ophthalmol. 2016;2016:7521478. doi:10.1155/2016/7521478.
  • Told R, Reiter GS, Orsolya A, Mittermuller TJ, Eibenberger K, Schlanitz FG, Arikan M, Pollreisz A, Sacu S, Schmidt-Erfurth U. Swept source optical coherence tomography angiography, fluorescein angiography, and indocyanine green angiography comparisons revisited: using a novel deep-learning-assisted approach for image registration. Retina. 2019. doi:10.1097/IAE.0000000000002695.
  • Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim RY, Sy JP, Schneider S, Group AS. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med. 2006;355(14):1432–44. doi:10.1056/NEJMoa062655.
  • Martin DF, Maguire MG, Fine SL, Ying GS, Jaffe GJ, Grunwald JE, Toth C, Redford M, Ferris FL 3rd. Comparison of age-related macular degeneration treatments trials research G. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results. Ophthalmology. 2012;119(7):1388–98. doi:10.1016/j.ophtha.2012.03.053.
  • Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, Kim RY, Group MS. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med. 2006;355(14):1419–31. doi:10.1056/NEJMoa054481.
  • Sustronck P, Miere A, Nguyen D, Souied E, Oubraham H Long-term follow up of macular neovascularization using optical coherence tomography angiography: pro re nata versus treat&extend regimens conference poster: 124 - A0305. ARVO 2019. Vancouver, BC 2019.
  • Xu D, Davila JP, Rahimi M, Rebhun CB, Alibhai AY, Waheed NK, Sarraf D. Long-term progression of Type 1 neovascularization in age-related macular degeneration using optical coherence tomography angiography. Am J Ophthalmol. 2018;187:10–20. doi:10.1016/j.ajo.2017.12.005.
  • Told R, Reiter GS, Mittermuller TJ, Schranz M, Reumueller A, Schlanitz FG, Weigert G, Pollreisz A, Sacu S, Schmidt-Erfurth U. Profiling neovascular age-related macular degeneration choroidal neovascularization lesion response to anti-vascular endothelial growth factor therapy using SSOCTA. Acta Ophthalmol. 2020. doi:10.1111/aos.14554.
  • Heier JS, Brown DM, Chong V, Korobelnik JF, Kaiser PK, Nguyen QD, Kirchhof B, Ho A, Ogura Y, Yancopoulos GD and others. Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration. Ophthalmology. 2012;119(12):2537–48. doi:10.1016/j.ophtha.2012.09.006.
  • Muakkassa NW, Chin AT, de Carlo T, Klein KA, Baumal CR, Witkin AJ, Duker JS, Waheed NK. Characterizing the effect of anti-vascular endothelial growth factor therapy on treatment-naive choroidal neovascularization using optical coherence tomography angiography. Retina. 2015;35(11):2252–59. doi:10.1097/IAE.0000000000000836.
  • Lumbroso B, Rispoli M, Savastano MC. Longitudinal optical coherence tomography-angiography study of Type 2 naive choroidal neovascularization early response after treatment. Retina. 2015;35(11):2242–51. doi:10.1097/IAE.0000000000000879.
  • Spaide RF. Optical coherence tomography angiography signs of vascular abnormalization with antiangiogenic therapy for choroidal neovascularization. Am J Ophthalmol. 2015;160(1):6–16. doi:10.1016/j.ajo.2015.04.012.
  • Yiu G, Chiu SJ, Petrou PA, Stinnett S, Sarin N, Farsiu S, Chew EY, Wong WT, Toth CA. Relationship of central choroidal thickness with age-related macular degeneration status. Am J Ophthalmol. 2015;159(4):617–26. doi:10.1016/j.ajo.2014.12.010.
  • Lipecz A, Miller L, Kovacs I, Czako C, Csipo T, Baffi J, Csiszar A, Tarantini S, Ungvari Z, Yabluchanskiy A and others. Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. Geroscience. 2019;41:813–45.
  • Lee B, Ahn J, Yun C, Kim SW, Oh J. Variation of retinal and choroidal vasculatures in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2018;59(12):5246–55. doi:10.1167/iovs.17-23600.
  • Ghasemi Falavarjani K, Iafe NA, Hubschman JP, Tsui I, Sadda SR, Sarraf D. Optical coherence tomography angiography analysis of the foveal avascular zone and macular vessel density after anti-VEGF therapy in eyes with diabetic macular edema and retinal vein occlusion. Invest Ophthalmol Vis Sci. 2017;58(1):30–34. doi:10.1167/iovs.16-20579.
  • Winegarner A, Wakabayashi T, Fukushima Y, Sato T, Hara-Ueno C, Busch C, Nishiyama I, Shiraki N, Sayanagi K, Nishida K and others. Changes in retinal microvasculature and visual acuity after antivascular endothelial growth factor therapy in retinal vein occlusion. Invest Ophthalmol Vis Sci. 2018;59(7):2708–16. doi:10.1167/iovs.17-23437.
  • Toto L, Borrelli E, Di Antonio L, Carpineto P, Mastropasqua R. Retinal vascular plexuses’ changes in dry age-related macular degeneration, evaluated by means of optical coherence tomography angiography. Retina. 2016;36(8):1566–72. doi:10.1097/IAE.0000000000000962.
  • Waldstein SM, Simader C, Staurenghi G, Chong NV, Mitchell P, Jaffe GJ, Lu C, Katz TA, Schmidt-Erfurth U. Morphology and visual acuity in aflibercept and ranibizumab therapy for neovascular age-related macular degeneration in the VIEW trials. Ophthalmology. 2016;123(7):1521–29. doi:10.1016/j.ophtha.2016.03.037.
  • Valler D, Feucht N, Lohmann CP, Ulbig M, Maier M. Diagnostic criteria: OCT angiography for retinal angiomatous proliferation (RAP lesions, type 3 neovascularization). Ophthalmologe. 2020;117(6):529–537. doi:10.1007/s00347-019-01003-6.
  • Told R, Baratsits M, Garhofer G, Schmetterer L. Early treatment diabetic retinopathy study (ETDRS) visual acuity. Ophthalmologe. 2013;110(10):960–65. doi:10.1007/s00347-013-2813-2.
  • Parravano M, Borrelli E, Sacconi R, Costanzo E, Marchese A, Manca D, Varano M, Bandello F, Querques G. A comparison among different automatically segmented slabs to assess neovascular AMD using swept source OCT angiography. Transl Vis Sci Technol. 2019;8(2):8. doi:10.1167/tvst.8.2.8.
  • Zudaire E, Gambardella L, Kurcz C, Vermeren S. A computational tool for quantitative analysis of vascular networks. PLoS One. 2011;6(11):e27385. doi:10.1371/journal.pone.0027385.
  • Zahid S, Dolz-Marco R, Freund KB, Balaratnasingam C, Dansingani K, Gilani F, Mehta N, Young E, Klifto MR, Chae B and others. Fractal dimensional analysis of optical coherence tomography angiography in eyes with diabetic retinopathy. Invest Ophthalmol Vis Sci. 2016;57(11):4940–47. doi:10.1167/iovs.16-19656.
  • Matet A, Daruich A, Zografos L. Radiation maculopathy after proton beam therapy for uveal melanoma: optical coherence tomography angiography alterations influencing visual acuity. Invest Ophthalmol Vis Sci. 2017;58(10):3851–61. doi:10.1167/iovs.17-22324.
  • Bhardwaj S, Tsui E, Zahid S, Young E, Mehta N, Agemy S, Garcia P, Rosen RB, Young JA. Value of fractal analysis of optical coherence tomography angiography in various stages of diabetic retinopathy. Retina. 2018;38(9):1816–23. doi:10.1097/IAE.0000000000001774.
  • Schindelin J, Arganda-Carreras I, Frise E, Kaynig V, Longair M, Pietzsch T, Preibisch S, Rueden C, Saalfeld S, Schmid B and others. Fiji: an open-source platform for biological-image analysis. Nat Methods. 2012;9(7):676–82. doi:10.1038/nmeth.2019.
  • Khoshnood B, Mesbah M, Jeanbat V, Lafuma A, Berdeaux G. Transforming scales of measurement of visual acuity at the group level. Ophthalmic Physiol Opt. 2010;30(6):816–23. doi:10.1111/j.1475-1313.2010.00766.x.
  • Sulzbacher F, Pollreisz A, Kaider A, Kickinger S, Sacu S, Schmidt-Erfurth U. Vienna eye study C. Identification and clinical role of choroidal neovascularization characteristics based on optical coherence tomography angiography. Acta Ophthalmol. 2017;95(4):414–20. doi:10.1111/aos.13364.
  • Perrott-Reynolds R, Cann R, Cronbach N, Neo YN, Ho V, McNally O, Madi HA, Cochran C, Chakravarthy U. The diagnostic accuracy of OCT angiography in naive and treated neovascular age-related macular degeneration: a review. Eye (Lond). 2019;33(2):274–82. doi:10.1038/s41433-018-0229-6.
  • Jia Y, Bailey ST, Wilson DJ, Tan O, Klein ML, Flaxel CJ, Potsaid B, Liu JJ, Lu CD, Kraus MF and others. Quantitative optical coherence tomography angiography of choroidal neovascularization in age-related macular degeneration. Ophthalmology. 2014;121(7):1435–44. doi:10.1016/j.ophtha.2014.01.034.
  • Kuehlewein L, Bansal M, Lenis TL, Iafe NA, Sadda SR, Bonini Filho MA, De Carlo TE, Waheed NK, Duker JS, Sarraf D. Optical coherence tomography angiography of Type 1 neovascularization in age-related macular degeneration. Am J Ophthalmol. 2015;160(4):739–48 e2. doi:10.1016/j.ajo.2015.06.030.
  • Lindner M, Fang PP, Steinberg JS, Domdei N, Pfau M, Krohne TU, Schmitz-Valckenberg S, Holz FG, Fleckenstein M. OCT Angiography-based detection and quantification of the neovascular network in exudative AMD. Invest Ophthalmol Vis Sci. 2016;57(14):6342–48. doi:10.1167/iovs.16-19741.
  • Mastropasqua L, Toto L, Borrelli E, Carpineto P, Di Antonio L, Mastropasqua R. Optical coherence tomography angiography assessment of vascular effects occurring after aflibercept intravitreal injections in treatment-naive patients with wet age-related macular degeneration. Retina. 2017;37(2):247–56. doi:10.1097/IAE.0000000000001145.
  • Huang D, Jia Y, Rispoli M, Tan O, Lumbroso B. Optical coherence tomography angiography of time course of choroidal neovascularization in response to anti-angiogenic treatment. Retina. 2015;35(11):2260–64. doi:10.1097/IAE.0000000000000846.
  • Farecki ML, Gutfleisch M, Faatz H, Rothaus K, Heimes B, Spital G, Lommatzsch A, Pauleikhoff D. Characteristics of type 1 and 2 CNV in exudative AMD in OCT-angiography. Graefes Arch Clin Exp Ophthalmol. 2017;255(5):913–21. doi:10.1007/s00417-017-3588-y.
  • Moult EM, Alibhai AY, Rebhun C, Lee B, Ploner S, Schottenhamml J, Husvogt L, Baumal CR, Witkin AJ, Maier A and others. Spatial distribution of choriocapillaris impairment in eyes with choroidal neovascularization secondary to age-related macular degeneration: A quantitative OCT angiography study. Retina. 2020;40(3):428–445. doi:10.1097/IAE.0000000000002556.
  • Faatz H, Farecki ML, Rothaus K, Gutfleisch M, Pauleikhoff D, Lommatzsch A. Changes in the OCT angiographic appearance of type 1 and type 2 CNV in exudative AMD during anti-VEGF treatment. BMJ Open Ophthalmol. 2019;4(1):e000369. doi:10.1136/bmjophth-2019-000369.
  • Cennamo G, Montorio D, D’Alessandro A, Napolitano P, D’Andrea L, Tranfa F. Prospective study of vessel density by optical coherence tomography angiography after intravitreal bevacizumab in exudative age-related macular degeneration. Ophthalmol Ther. 2020;9(1):77–85. doi:10.1007/s40123-019-00221-0.
  • Lee SC, Tran S, Amin A, Morse LS, Moshiri A, Park SS, Yiu G. Retinal vessel density in exudative and non-exudative age-related macular degeneration on optical coherence tomography angiography. Am J Ophthalmol. 2019. PLoS One. 2019;14(5):e0217109. doi:10.1371/journal.pone.0217109.
  • Kanadani TCM, Veloso CE, Nehemy MB. Subfoveal choroidal thickness in eyes with neovascular age-related macular degeneration treated with anti-vascular endothelial growth factor agents. Ophthalmologica. 2018;240(4):200–07. doi:10.1159/000488254.
  • Fayed AE, Fawzi AA. Projection resolved optical coherence tomography angiography to distinguish flow signal in retinal angiomatous proliferation from flow artifact. PLoS One. 2019 May 15;14(5):e0217109. doi:10.1371/journal.pone.0217109.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.