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Annals of Tropical Paediatrics
International Child Health
Volume 8, 1988 - Issue 2
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Original Articles

The effects of antimalarials and folate supplements on haematological indices and red cell folate levels in Gambian children

Nigel J. FullerMedical Research Council Dunn Nutrition Unit, Cambridge, U.K.
,
Christopher J. BatesMedical Research Council Dunn Nutrition Unit, Cambridge, U.K.
,
Richard J. HayesTropical Epidemiology Unit, School of Hygiene and Tropical Medicine, London, U.K.
,
Andrew K. BradleyMedical Research Council Laboratories, Fajara, Banjul, The Gambia.
,
Alice M. GreenwoodMedical Research Council Laboratories, Fajara, Banjul, The Gambia.
,
Steven TullochMedical Research Council Laboratories, Fajara, Banjul, The Gambia.
&
Brian M. GreenwoodMedical Research Council Laboratories, Fajara, Banjul, The Gambia.
 show all
Pages 61-67 | Received 24 Nov 1987, Published online: 13 Jul 2016

References

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  • Fleming AF, Warreil DA, Dickmeiss H. Co-trimoxazole and blood. Lancet 1974; ii: 284–5.
  • Ansdell VE, Wright SG, Hutchinson DAB. Megaloblastic anaemia associated with combined pyrimethamine and co-trimoxazole administration. Lancet 1977: ii; 1257.
  • Sturchler D, Holzer B. Low serum folate among persons taking Fansidar (pyrimethamine plus sulphadoxine) for prophylaxis of malaria. Acta Tropica 1980; 37: 243–8.
  • Laing SRS. Refractory anaemia, a problem in diagnosis and epidemiology in a tea garden in Assam. J Trop Med Hyg 1957; 60: 131–6.
  • Greenwood BM, Groenendaal, F, Bradley AK, Greenwood AM, Shenton FC, Tulloch S. Ethnic differences in the prevalence of splenomegaly and malaria in The Gambia. Ann Trop Med Parasitol. In press.
  • Greenwood BM, Bradley AK, Greenwood AM, Oldfield FSJ. A record system for drug administration by illiterate village health workers. Trans R Soc Trop Med Hyg. In press.
  • Greenwood BM, Greenwood AM, Bradley AK. et al. ELISA tests for dapsone and pyrimethamine and their application to the monitoring of a malaria chemoprophylaxis programme. Bull WHO 1986; 81: 476–86.
  • Fuller NJ, Bates CJ, Scott KJ. A radioassay for folate in red cells. Clin Chim Acta 1983; 131: 343–8.
  • Hoffbrand AV, Newcombe BFA, Mollin DL. Method of assay of red cell folate activity and the value of the assay as a test of folate deficiency. J Clin Pathol 1966; 19: 17–28.
  • Bates CJ, Fuller NJ, Prentice AM. Folate status during pregnancy and lactation in a West African rural community. Hum Nutr Clin Nutr 1986; 40C: 3–13.
  • Bjorkman A, Brohult J, Pehrson PO. et al. Monthly antimalarial chemotherapy to children in a holoendemic area of Liberia. Ann Trop Med Parasitol 1986; 80: 155–67.
  • Bradley-Moore AM, Greenwood BM, Bradley AK. et al. Malaria chemoprophylaxis with chloroquine in young Nigerian children. 4. Its effect on haematological measurements. Ann Trop Med Parasitol 1985; 79: 585–96.
  • Oppenheimer SJ, Cashin P. Serum and red cell folate levels associated with malaria parasitaemia. Trans R Soc Trop Med Hyg 1986; 80: 169–70.
  • Bruce-Chwatt LJ, Hutchinson DBA. Maloprim and agranulocytosis. Lancet 1983; ii: 1487–8.

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