Effects on CYP1A of the polycyclic musk tonalide (AHTN) in single and co-exposure with benzo(a)pyrene and 3,3′-4,4′,5-pentachlorobiphenyl in the PLHC-1 fish cell line

References

• Gooding , M. P. , Newton , T. J. , Bartsch , M. R. and Hornbuckle , K. C. 2006 . Toxicity of synthetic musks to early life stages of the freshwater mussel . Lampsilis cardium, Arch. Environ. Contam. Toxicol. , 42 : 437 – 446 .
   Google Scholar
• Kallenborn , R. , Gatermann , R. , Planting , S. , Rimkus , G. G. , Luckenbach , T. and Epel , D. 2005 . Nitromusk and polycyclic musk compounds as long-term inhibitors of cellular xenobiotic defence systems mediated through multidrug transporters . Environ. Health Persp. , 113 : 17 – 24 .
   PubMedGoogle Scholar
• Verbruggen , E. M.J. , van Loon , W. M.G.M. , Tonkes , M. , van Duijn , P. , Seinen , W. and Hermens , J. L.M. 1999 . Biomimetic extraction as a tool to identify chemicals with high bioconcentration potential: An illustration by two fragrances in sewage treatment plant effluents and surface water . Environ. Sci. Technol. , 34 : 801 – 806 .
   Google Scholar
• Sumner , N. R. , Guitart , C. , Fuentes , G. and Readman , J. W. 2010 . Inputs and distributions of synthetic musk fragrances in an estuarine and coastal environment; a case study . Environ. Pollut. , 158 : 215 – 222 .
   PubMedGoogle Scholar
• Fooken , C. 2004 . “ Synthetic musks in suspended particulate matter (SPM) sediment and sewage sludge ” . In The Handbook of Environmental Chemistry , Edited by: Rimkus , G. G. Vol. 3 , 233 – 244 . New York : Springer . Part X
   Google Scholar
• Rimkus , G. G. 1999 . Polycyclic fragrances in the aquatic environment . Toxicol. Lett. , 111 : 37 – 56 .
   PubMed Web of Science ®Google Scholar
• Draisci , R. , Marchiafava , C. , Ferretti , E. , Palleschi , L. , Catellani , G. and Anastasio , A. 1998 . Evaluation of musk contamination of freshwater fish in Italy by accelerated solvent extraction and gas chromatography with mass spectrometric detection . J. Chromatogr. A , 814 : 187 – 197 .
   PubMedGoogle Scholar
• Gaterman , R. , Biselli , S. , Hühnerfuss , H. , Rimkus , G. , Hecker , M and Karbe , L. 2002 . Synthetic musks in the environment. Part 1: Species dependent bioaccumulation of polycyclic and nitro musk fragrances in freshwater fish and mussels . Arch. Environ. Contam. Toxicol. , 42 : 437 – 446 .
   PubMedGoogle Scholar
• Rudel , H. , Bohmer , W. and Schroter-Kermani , C. 2006 . Retrospective monitoring of synthetic musk compounds in aquatic biota from german rivers and coastal area . J. Environ. Monit. , 8 : 812 – 823 .
   PubMedGoogle Scholar
• Carlsson , G. and Norrgren , L. 2004 . Synthetic musk toxicity to early life stages of zebrafish . (Danio rerio), Arch. Environ. Contam. Toxicol. , 46 : 102 – 105 .
   PubMed Web of Science ®Google Scholar
• Wollenberger , L. , Breitholtz , M. , Ole , K. K. and Bengtsson , B. E. 2003 . Inhibition of larval development of the marine copepod Acartia tonsa by four synthetic musk substances . Sci. Total Environ. , 305 : 53 – 64 .
   PubMedGoogle Scholar
• Balk , F. and Ford , R. A. 1999 . Environmental risk assessment for the polycyclic musks, AHTN and HHCB – II. Effect assessment and risk characterisation . Toxicol. Lett. , 111 : 81 – 94 .
   PubMed Web of Science ®Google Scholar
• Schreurs , R. H.M.M. , Legler , J. , Artola-Garicano , E. , Sinnige , T. L. , Lanser , H. and Van Der Burg , B. 2004 . In vitro and in vivo antiestrogenic effects of polycyclic musks in zebrafish . Environ. Sci. Technol. , 38 : 997 – 1002 .
   PubMed Web of Science ®Google Scholar
• Yamauchi , R. , Ishibashi , H. , Hirano , M. , Mori , T. , Kim , J.-W. and Arizono , K. 2008 . Effects of synthetic polycyclic musks on estrogen receptor, vitellogenin, pregnane X receptor, and cytochrome P450 3A gene expression in the livers of male medaka . (Oryzias latipes), Aquat. Toxicol. , 90 : 261 – 268 .
   PubMed Web of Science ®Google Scholar
• Schnell , S. , Martin-Skilton , R. , Fernandes , D. and Porte , C. 2009 . The interference of nitro- and polycyclic musks with endogenous and xenobiotic metabolizing enzymes in carp: An in vitro study . Environ. Sci. Technol. , 43 : 9458 – 9464 .
   PubMedGoogle Scholar
• Randelli , E. , Rossini , V. , Corsi , I. , Focardi , S. , Fausto , A. M. , Buonocore , F. and Scapigliati , G. 2011 . Effects of the polycyclic ketone tonalide (AHTN) on some cell viability parameters and transcription of P450 and immunoregulatory genes in rainbow trout RTG-2 cells . Toxicol. In Vitro , doi:10.1016/j.tiv.2011.06.003
   PubMedGoogle Scholar
• Schnell , S. , Bols , N. C. , Barata , C. and Porte , C. 2009 . Single and combined toxicity of pharmaceuticals and personal care products (PPCPs) on the rainbow trout liver cell line RTL-W1 . Aquat. Toxicol. , 93 : 244 – 252 .
   PubMed Web of Science ®Google Scholar
• Fent , F. 2001 . Fish cell lines as versatile tools in ecotoxicology: Assessment of cytotoxicity, cytochrome P4501A induction potential and estrogenic activity of chemicals and environmental samples . Toxicol. In Vitro , 15 : 477 – 488 .
   PubMed Web of Science ®Google Scholar
• Hahn , M. E. 1998 . The aryl hydrocarbon receptor. A comparative perspective . Comp. Biochem. Physiol. C , 121 : 23 – 54 .
   PubMed Web of Science ®Google Scholar
• Smeets , J. M.W. , Voormolen , A. , Tillitt , D. E. , Everaarts , J. M. and Seinen , W. 1999 . Cytochrome P4501A induction, benzo[a]pyrene metabolism, and nucleotide adduct formation in fish hepatoma cells: Effect of preexposure to 3,3′,4,4′,5-pentachlorobiphenyl . Environ. Toxicol. Chem. , 18 : 474 – 480 .
   Google Scholar
• Celander , M. , Bremer , J. , Hahn , M. E. and Stegeman , J. J. 1997 . Glucocorticoid – xenobiotic interactions: Dexamethasone-mediated potentiation of cytochrome P4501A induction by β-maphtoflavonein a fish hepatoma cell line (PLHC-1) . Environ. Toxicol. Chem. , 16 : 900 – 907 .
   Google Scholar
• Fent , K. and Batscher , R. 2000 . Cytochrome P4501A induction potencies of polycyclic aromatic hydrocarbons in a fish hepatoma cell line: Demonstration of additive interactions . Environ. Toxicol. Chem. , 19 : 2047 – 2058 .
   Web of Science ®Google Scholar
• Repetto , G. , del Peso , A. and Zurita , J. L. 2008 . Neutral Red uptake assay for the estimation of cell viability/cytotoxicity . Nat. Prot. , 3 : 1125 – 1132 .
   PubMed Web of Science ®Google Scholar
• Della Torre , C. , Monti , M. , Focardi , S. and Corsi , I. 2011 . Time-dependent modulation of cyp1a gene transcription and EROD activity by musk xylene in PLHC-1 and RTG-2 fish cell lines . Toxicol. In Vitro , doi 10.1016/j.tiv.2011.05.025
   PubMedGoogle Scholar
• Pfaffl , M. 2001 . A new mathematical model for relative quantification in real-time RT-PCR . Nucleic Acid Res. , 29 : 2002 – 2007 .
   Web of Science ®Google Scholar
• Traven , L. , Žaja , R. , Lončar , J. , Smital , T. and Mićović , V. 2008 . CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – in vitro evaluation using the PLHC-1 fish hepatoma cell line . Toxicol. In Vitro , 22 : 1648 – 1656 .
   PubMed Web of Science ®Google Scholar
• Bradford , M. 1976 . A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding . Anal. Biochem. , 72 : 248 – 254 .
   PubMed Web of Science ®Google Scholar
• OSPAR Commission . 2004 . Ospar Background Document on Musk Xylene and Other Musks . Hazardous Substances Series, OSPAR Commission, London , : 45 Available at http://www.ospar.org/documents/dbase/publications/p00200_BD%20on%20musk%20xylene.pdf
   Google Scholar
• Artola-Garicano , E. , Sinnige , T. L. , van Holsteijn , I. , Vaes , W. H.J. and Hermens , J. L.M. 2003 . Bioconcentration and acute toxicity of polycyclic musks in two benthic organisms (Chironomus riparius and Lumbriculus variegatus) . Environ. Toxicol. Chem. , 22 : 1086 – 1092 .
   PubMedGoogle Scholar
• Steinberg , P. , Fischer , T. , Arand , M. , Park , E. , Elmadfa , I. , Rimkus , G. , Brunn , H. and Dienes , H-P. 1999 . Acute hepatotoxicity of the polycyclic musk 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthaline (AHTN) . Toxicol. Lett. , 111 : 151 – 160 .
   PubMedGoogle Scholar
• Chen , G. , Konstantinov , A. D. , Joyce , E. M. , Bols , N. C. and Bunce , N. J. 2001 . Synthesis of polybrominated diphenyl ethers and their capacity to induce CYP1A by the Ah receptor mediated pathway . Environ. Sci. Technol. , 35 : 3749 – 3756 .
   PubMed Web of Science ®Google Scholar
• Hestermann , E. V. , Stegeman , J. J. and Hahn , M. E. 2000 . Relative contributions of affinity and intrinsic efficacy to aryl hidrocarbon receptor ligand potency . Toxicol. Appl. Pharmacol. , 168 : 160 – 172 .
   PubMed Web of Science ®Google Scholar
• Balk , F. and Ford , R. A. 1999 . Environmental risk assessment for the polycyclic musks AHTN and HHCB in the EU I. Fate and exposure assessment . Toxicol. Lett. , 111 : 57 – 79 .
   PubMed Web of Science ®Google Scholar