Biochemical Markers as a Response Guide for Steroid Therapy in Asthma

References

• Vaughan J, Ngamtrakulpanit L, Pajewski T N, et al. Exhaled breath condensate pH is a robust and reproducible assay of airway acidity. Eur Respir J 2003; 22: 889–894
   PubMed Web of Science ®Google Scholar
• Moeller A, Kielbasa B. Exhaled breath condensate and other markers in exhaled air. Prog Respir Res 2005; 33: 190–202
   Google Scholar
• Emelyanov A, Fedoseev G, Abulimity A, et al. Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients. Chest 2001; 120: 1136–1139
   PubMed Web of Science ®Google Scholar
• Al Obaidi A H. Validity assessment of different biochemical markers in asthma. PhD Thesis, Tikrit University College of Medicine. 2006
   Google Scholar
• Kostikas K, Papatheodorou G, Ganas K, et al. pH in expired breath condensate of patients with inflammatory airway diseases. Am J Respir Crit Care Med 2002; 165: 1364–1370
   PubMed Web of Science ®Google Scholar
• Hunt J F, Fang K, Malik R, et al. Endogenous airway acidification. Implications for asthma pathophysiology. Am J Respir Crit Care Med 2000; 161: 694–699
   PubMed Web of Science ®Google Scholar
• Loukides Loukides S, Bouros D, Papatheodorou G, Panagou P, Siafakas N. The relationship among hydrogen peroxide in expired breath condensate, airway inflammation and asthma severity. Chest 2002; 121: 338–346
   PubMed Web of Science ®Google Scholar
• Rahman I. Reproducibility of oxidative stress biomarkers in breath condensate: are they reliable?. Eur Respir J 2004; 23: 183–184
   PubMed Web of Science ®Google Scholar
• Barnes P J. Molecular basis for corticosteroid action in asthma. Chem Immunol 2000; 78: 72–80
   PubMedGoogle Scholar
• Jatakanon A, Karitonovo S, Lim S, et al. Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma. Thorax 1999; 54: 108–114
   PubMed Web of Science ®Google Scholar
• Global strategy for asthma management and prevention. Bethesda, National Institutes of Health. National Heart, Lung and Blood Institute. 1997, NHLBI/WHO workshop report 2, Publication 97–4051A
   Google Scholar
• Gallati H, Pracht I. Horseradish peroxidase: kinetic studies and optimumization of peroxidase activity determination using substrate H2O2 and tetramethyl benzidine. J Clin Chem Clin Biochem 1985; 23: 453–460
   PubMedGoogle Scholar
• Janero D R. Malondialdehyde and thiobarbituric acid reactivity as diagnostic indicies of lipid peroxidation and peroxidative tissue injury. Free Rad Biol Med 1990; 9: 515–540
   PubMed Web of Science ®Google Scholar
• Kampa M, Nistikaki A, Tsaousis V, et al. A new automated method for the determination of the total antioxidant capacity of human plasma, based on crocin bleaching assay. BMC Clin Pathol 2002; 2: 3–21
   PubMedGoogle Scholar
• Barnes P J, Greening A P, Crompton G K. Glucocorticoid resistance in asthma. Am J Respir Crit Care Med 1995; 181: 33–40
   Google Scholar
• Szefler S J, Leung D Y. Glucocorticoid resistant asthma: pathogenesis and clinical implications for management. Eur respire J 1997; 10: 1640–1647
   PubMed Web of Science ®Google Scholar
• Barnes P J, Woolcock A J. Difficult asthma. Eur respire J 1998; 12: 1209–1218
   PubMed Web of Science ®Google Scholar
• Adcock I M, Brown C R, Shirasaki H, Barnes P J. Effects of dexamethasone on cytokine and phorbol ester stimulated c-Fos and c-Jun DNA binding and gene expression in human lung. Eur Respir J 1994; 7: 2117–2123
   PubMed Web of Science ®Google Scholar
• Adcock I M, Lane S J, Brown C A, Lee T H, Barnes P J. Abnormal glucocorticoids receptor / AP-1 interaction in steroid resistant asthma. J Exp Med 1995; 182: 1951–1958
   PubMed Web of Science ®Google Scholar
• Adcock I M, Brady H, Lim S, Karin M, Barnes P J. Increased JUN kinase activity in peripheral blood monocyte from steroid resistant asthmatic subjects. Am J Respir Crit Care Med 1997; 155: A288
   Google Scholar
• Barnes P J, Adcock I M. Steroid resistant asthma. Q J Med 1995; 88: 455–468
   Google Scholar
• Cypcar D, Busse W W. Steroid resistant asthma. J Allergy Clin Immunol 1993; 92: 362–372
   PubMed Web of Science ®Google Scholar
• Lane S J, Atkinson B A, Swimmanthan R, Lee T H. Hypothalamic – pituitary axis in corticosteroid resistant asthma. Am J Respir Crit Care Med 1996; 153: 1510–1514
   PubMed Web of Science ®Google Scholar
• Panettieri R A. Effect of corticosteroid on structural cells in asthma and COPD. Proceeding ATS 2004; 1: 231–234
   Google Scholar
• Stewart R M, Weir E K, Montgomery M R, Niewoehner D E. Hydrogen peroxide contracts airway smooth muscle: a possible endogenous mechanism. Respir Physiol 1981; 45: 333–342
   PubMedGoogle Scholar
• Rhoden K J, Barnes P J. Effect of hydrogen peroxide on guinea pig tracheal muscle in vitro: role of cyclooxygenase and airway epithelium. Br J Pharmacol 1989; 98: 325–330
   PubMed Web of Science ®Google Scholar
• Antczak A, Nowak D, Shariati B, Krol M, Piasecka G, Kurmanowska Z. Increased hydrogen peroxide and thiobarbituric acid reactive products in expired breath condensate of asthmatic patients. Eur Respir J 1997; 10: 1235–1241
   PubMed Web of Science ®Google Scholar
• Synek M, Beasley R, Frew A J, et al. Cellular infiltration of the airways in asthma of varying severity. Am J Respir Crit Care Med 1996; 154: 224–230
   PubMed Web of Science ®Google Scholar
• Vrugt B, Djukanovic R, Bron A, Aalbers R. New insights into the pathogenesis of severe corticosteroid – dependent asthma. J Allergy Clin Immunol 1996; 98: S22–S26
   PubMed Web of Science ®Google Scholar
• Wenzel S E, Szefler S J, Leung D Y, et al. Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med 1997; 156: 737–743
   PubMed Web of Science ®Google Scholar
• Jatakanon A, Mohamad J B, Lim S, et al. Neutrophils may contribute to the pathogenesis of airway inflammation in steroid – dependent intractable asthma. Am J respire Crit Care Med 1998; 157: A875
   Google Scholar
• Jonat C, Rahsdorf H J, Park K K, et al. Anti tumor promotion and ant inflammation: down modulation of AP-1 activity by glucocorticoids hormone. Cell 1990; 62: 1189–1204
   PubMed Web of Science ®Google Scholar
• Yang – Yen H, Chambard J, Sun Y, et al. Transcriptional interference between c-Jun and the glucocorticoids receptor: mutual inhibition of DNA binding due to direct protein interaction. Cell 1990; 62: 1205–1215
   PubMed Web of Science ®Google Scholar
• Peters M J, Yates D H, Chung K F, Barnes P J. ß2 agonist dose reduction: strategy and early results. Thorax 1993; 48: 1066
   Google Scholar
• Sears M R. Dose reduction of beta agonists in asthma. Lancet 1991; 338: 1331–1332
   PubMed Web of Science ®Google Scholar
• Nijkamp F P, Henricks P A. Receptors in airway disease. Beta-adrenoreceptors in lung inflammation. Am Rev Respir Dis 1990; 141(supplement)S145–150
   PubMed Web of Science ®Google Scholar
• Katsumata μ, Miura M, Ichinose M, et al. Oxygen radicals produce airway constriction and hyperresponsiveness in anesthetized cats. Am Rev Respir Dis 1990; 141: 1158–1161
   PubMed Web of Science ®Google Scholar
• Abe M K, Chao T S, Solway J, Rosner M R, Hershenson M B. Hydrogen peroxide stimulates mitogen activated protein kinase in bovine tracheal myocytes: implications for human airway disease. Am J Respir Cell Mol Biol 1994; 11: 577–585
   PubMed Web of Science ®Google Scholar