The Anti-inflammatory Effects of Inhaled Corticosteroids versus Anti-leukotrienes on the Lymphocyte P-Glycoprotein (PGP) Expression in Asthmatic Children

References

• Bjerner L. Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation. J Allergy Clin Immunol 2007; 120: 1269–1275
   PubMedGoogle Scholar
• Kruh G D, Guo Y, Hopper-Borge E, Belinsky M G, Chen Z-S. ABCC10, ABCC11, and ABCC12. Eur J Physiol 2007; 435: 675–684
   Google Scholar
• Ambudkar S V, Kim I W, Sauna Z E. The power of the pump: mechanism of action of P-glycoprotein (ABCB1). Eur L Phamrm Sci 2006; 27: 392–400
   PubMed Web of Science ®Google Scholar
• Van d er, Deen M, de Vries E GE, Timens W, Scheper R J, Timmer-Bosscha H, Postma D S. ATP-binding cassette (ABC) transporters in normal nad pathological lung. Respir Res 2005; 56: 1–16
   Google Scholar
• Chen Z S, Guo Y, Belinsky M G, Kotova E, Kruh G D. Transport of bile acids, sulfated steroide, estradiol 17-beta-D-glucuronide, and leukotrine C4 by human multidrug resistence protein(ABCC11). Mol Pharmacol 2005; 67: 545–557
   PubMed Web of Science ®Google Scholar
• Ren X-Q, Furukawa T, Haraguchi M, Sumizawa T, Aoki S, Kopbayashi M, Akiyama S-I. Function of the ABC signature sequences in the human multidrug resistence protein 1. Mol Pharmacol 2004; 65: 1536–1542
   PubMedGoogle Scholar
• Campbell L, Abulrob A N, Kandalaft L E, Plummer S, Hollins A J, Gibbs A, Gumbleton M. Constitutive expression of p-glycoprotein in normal lung alveolar epithelium and functionality in primary alveolar epithelial cultures. J Pharmacol Exp Ther 2003; 304: 441–452
   PubMed Web of Science ®Google Scholar
• Litman T, Druley T E, Stein W D, Bates S E. From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci 2001; 58: 931–959
   PubMed Web of Science ®Google Scholar
• Sarau M H, Ames R S, Chmabers J, Ellis C, Elshourbagy N, Foley J J, Schmidt D B, Muccitelli R M, Jenkins O, Murdock P R, Herrity N C, Halsey W, Sathe G, Muir A I, Nuthulaganti P, Dytko G M, Buckley P T, Wilson S, Bergggsma D J, Hay D WP. Identification, molecular cloning, expression, and characterization of cysteinyl leukotriene receptor. Mol Pharmacol 1999; 56: 657–663
   PubMed Web of Science ®Google Scholar
• Stelmach I, Majak P, Jerzynska J, Kuna P. The effect of treatment with montelukast on in vitro interleukin-10 production of mononuclear cells of children with asthma. Clin Exp Allergy 2005; 35: 213–220
   PubMedGoogle Scholar
• Nakano R, Oka M, Nakamura T, Fukuda M, Kawabata S, Terashi K, Tsukamoto K, Noguchi Y, Soda H, Kohno S. A leukotriene receptor antagonist, ONO-1078, modulates drug sensitivity and leukotriene C4 efflux in lung cancer cells expressing multidrug resistance protein. Biochem Biophys Res Commun 1998; 251: 307–312
   PubMed Web of Science ®Google Scholar
• Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. 2002, NHLBI/WHO. NIH Publication No. 02-3659
   Google Scholar
• Hare J T, Elliott D P. Grapefruit juice and potential drug interactions. Konsult Pharm 2003; 18: 466–472
   PubMedGoogle Scholar
• Den Boer M L, Zwaan C M, Pieters R, Kazemier K M, Rottier M M, Flens M J, Scheper R J, Veerman A J. Optimal immunocytochemical and flow cytometric detection of P-gp, MRP and LRP in childhood acute lymphoblastic leukemia. Leukemia 1997; 11: 1078–1085
   PubMed Web of Science ®Google Scholar
• Sobende P O, Kercsmar C M. Inhaled corticosteroids in asthma management. Respir Care 2008; 53: 625–633
   PubMedGoogle Scholar
• Schwiebert E M. ABC transporte-faciliated ATP conductive transport. Am J Physiol 1999; 276: C1–C8
   Google Scholar
• Adcock I M, Ford P A, Bhasvar P, Ahmad T, Chung K F. Steroid resistance in asthma: mechanisms and treatment options. Curr Allergy Asthma Rep 2008; 8: 171–178
   PubMed Web of Science ®Google Scholar
• Funaki S, Takahashi S, Wada N, Murakami H, Farada K. Multiple drug-resistant gene 1 in children with steroid-sensitive nephrotic syndrome. Pediatr Int. 2008; 50: 159–161
   PubMedGoogle Scholar
• Ho E A, Piquette-Miller M. Regulation of multidrug resistance by pro-inflammatory cytokines. Curr Cancer Drug Targets 2006; 6: 295–311
   PubMed Web of Science ®Google Scholar
• Kuzuya Y, Adachi T, Hara H, Anan A, Izuhara K, Nagai H. Induction of drug-metabolizing enzymes and transporters in human bronchial epithelial cells by beclomethasone dipropionate. IUBMB Life 2004; 56: 355–359
   PubMed Web of Science ®Google Scholar
• Henriksson G, Norlander T, Zheng X, Sterna P, Sestrin K M. Expression of P-glycoprotein 170 in nasal mucosa may be increased with topical steroids. Am J Rhinol 1997; 11: 317–321
   PubMedGoogle Scholar
• Montano E, Schmitz M, Laser K, Simon H-U. P-Glycoprotein expression in circulating blood leukocytes of patiens with steroid resistant asthma. J Incest Allergol Clin Immunol 1996; 6: 14–21
   PubMedGoogle Scholar
• Steinke J W, Culp J A. Leukotriene synthesis inhibitors versus antagonists: The pros and cons. Curr Allergy Asthma Rep 2007; 7: 126–133
   PubMed Web of Science ®Google Scholar
• Stelmach I, Jerzynska J, Kuna P. A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein (ECP), soluble interleukin 2 receptor (sIL-2R), IL-4, and soluble intercellular adhesion molecule 1 (sICAM-1) in children with asthma. J Allergy Clin Immunol 2002; 109: 257–263
   PubMed Web of Science ®Google Scholar
• Evans J F, Ferguson A D, Mosley R T, Hutchinson J H. What's all the FLAP about:5-lipoxygenase-activating protein inhibitors for inflammatory diseases. Trends Pharmacol Sci 2007; 29: 72–78
   Google Scholar