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Original Articles

DNA methylation levels associated with race and childhood asthma severity

, PhD, , MD, MSc, FAAAAI, , BS, , MS, , PhD, , MPH, CIEC & , PhD show all
Pages 825-832 | Received 17 Jun 2016, Accepted 22 Nov 2016, Published online: 10 Feb 2017

References

  • Akinbami LJ, Moorman JE, Bailey C, Zahran HS, King M, Johnson CA, et al. Trends in asthma prevalence, health care use and mortality in the United States, 2001–2010. NCHS Data Brief 2012; May(94):1–8.
  • Marks GB. Environmental factors and gene-environment interactions in the aetiology of asthma. Clin Exp Pharmacol Physiol 2006;33:285–289.
  • Barnes PJ. Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009;6:693–696.
  • Kabesch M, Michel S, Tost J. Epigenetic mechanisms and the relationship to childhood asthma. Eur Respir J 2010;36:950–961.
  • Yang IV, Schwartz DA. Epigenetic mechanisms and the development of asthma. J Allergy Clin Immunol 2012;130:1243–1255.
  • Bégin P, Nadeau KC. Epigenetic regulation of asthma and allergic disease. Allergy Asthma Clin Immunol 2014;10:27.
  • Vercelli D. Does epigenetics play a role in human asthma? Allergol Int 2016; pii: S1323-8930(15)00213-0.
  • Keet CA, McCormack MC, Pollack CE, Peng RD, McGowan E, Matsui EC. Neighborhood poverty, urban residence, race/ethnicity, and asthma: rethinking the inner-city asthma epidemic. J Allergy Clin Immunol 2015;135:655–662.
  • Matsui EC. Environmental exposures and asthma morbidity in children living in urban neighborhoods. Allergy 2014;69:553–558.
  • Northridge J, Ramirez OF, Stingone JA, Claudio L. The role of housing type and housing quality in urban children with asthma. J Urban Health 2010;87:211–224.
  • Pacheo CM, Ciaccio CE, Daley CM, DiDonna A, et al. Homes of low-income minority families with asthmatic children have increased condition issues. Allergy Asthma Pro 2014;35:467–474.
  • Flores C, Ma S-F, Wade MS, Pérez-Méndez L, et al. African ancestry is associated with asthma risk in African Americans. PLoS ONE 2012;7(1):e26807.
  • Akinbami LJ, Moorman JE, Simon AE, Schoendorf KC. Trends in racial disparities for asthma outcomes among children 0–17 years, 2001–2010. J Allergy Clin Immunol 2014;134:547–553.
  • Johnson L, Ciaccio C, Barnes CS, Kennedy K, Forrest E, Gard LC, Pacheco F, Dowling P, Portnoy JM.. Low cost interventions improve indoor air quality and children's health. Allergy Asthma Proc. 2009 Jul-Aug;30(4):377–85.
  • Rönn T, Volkov P, Davegårdh C, Dayeh T, Hall E, Olsson AH, et al. A six months exercise intervention influences the genome wide DNA methylation pattern in human adipose tissue. PLoS Genet 2013;9(6):e1003572.
  • Moleres A, Campión J, Milagro FI, Marcos A, Campoy C, Garagorri JM, et al. Differential DNA methylation patterns between high and low responders to a weight loss intervention in overweight or obese adolescents: the EVASYON study. FASEB J 2013;27:2504–2512.
  • Zhang FF, Cardarelli R, Carroll J, Fulda KG, Kaur M, Gonzalez K, et al. Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood. Epigenetics 2011;6:623–629.
  • El-Maari O, Becker T, Junen J, Manzoor SS, Diaz-Lacava A, Schwaab R, et al. Gender specific differences in levels of DNA methylation at selected loci from human total blood; a tendency toward higher methylation levels in males. Hum Genet 2007;122:505–514.
  • Zhu ZZ, Hou L, Bollati V, Tarantini L, Marinelli B, Cantone L, et al. Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis. Int J Epidemiol 2012;41:126–139.
  • Wilson AS, Power BE, Molloy PL. DNA hypomethylation and human diseases. Biochim Biophys Acta 2007;1775:138–162.
  • Stefan M, Zhang W, Concepcion E, Yi Z, Tomer Y. DNA methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology. J Autoimmun 2014;50:33–37.
  • McGuinness D, McGlynn LM, Johnson PC, MacIntyre A, Batty GD, Burns H, et al. Socio-economic status is associated with epigenetic differences in the pSoBid cohort. Int J Epidemiol 2012;41:151–160.
  • Stringhini S, Polidoro S, Sacerdote C, Kelly RS, van Veldhoven K, Agnoli C, et al. Life-course socioeconomic status and DNA methylation of genes regulating inflammation. Int J Epidemiol 2015;44:1320–1330.
  • Terry MB, Ferris JS, Pilsner R, Flom JD, Tehranifar P, Santella RM, et al. Genomic DNA methylation among women in a multiethnic New York city birth cohort. Cancer Epidemiol Biomarkers Prev 2008;17:2306–2310.
  • Axume J, Smith SS, Pogribny IP, Moriarty DJ, Caudill MA. Global leukocyte DNA methylation is similar in African American and Caucasian women under conditions of controlled folate intake. Epigenetics 2007;2:66–68.
  • Adkins RM, Krushkal J, Tylavsky FA, Thomas F. Racial differences in gene-specific DNA methylation levels are present at birth. Birth Defects Res A Clin Mol Teratol 2011;91:728–736.
  • Perng W, Rozek LS, Mora-Plazas M, Duchin O, Marin C, Forero Y, et al. Micronutrient status and global DNA methylation in school-age children. Epigenetics 2012;7:1133–1141.
  • Hellman A, Chess A. Gene body-specific methylation on the active X chromosome. Science 2007;315:1141–1143.
  • El-Maarri O, Walier M, Behne F, van Üüm J, Singer H, Diaz-Lacava A, et al. Methylation at global line-1 repeats in human blood are affected by gender but not by age or natural hormone cycles. PLoS ONE 2011;6:e16252.
  • Gomes MV, Toffoli LV, Arruda DW, Soldera LM, Pelosi GG, Neves-Souza RD, et al. Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities. PLoS ONE 2012;7:e52570.
  • Romani M, Pistillo MP, Banelli B. Environmental epigenetics: crossroad between public health, lifestyle, and cancer prevention. Biomed Res Int 2015;2015:587983.
  • Pavanello S, Bollati V, Pesatori AC, Kapka L, Bolognesi C, Bertazzi PA, et al. Global and gene-specific promoter methylation changes are related to anti-B[a] PDE-DNA adduct levels and influence micronuclei levels in polycyclic aromatic hydrocarbon-exposed individuals. Int J Cancer 2009;125:1692–1697.
  • Breton CV, Byun H-M, Wenten M, Pan F, Yang A, Gilliland FD. Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Respir Crit Care Med 2009;180:462–467.
  • Runyon RS, Cachola LM, Rajeshuni N, Hunter T, Garcia M, Ahn R, et al. Asthma discordance in twins is linked to epigenetic modifications of T cells. PLoS ONE 2012;7:e48796.
  • Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, et al. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med 2009;179:572–578.
  • Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, et al. DNA methylation and childhood asthma in the inner city. J Allergy Clin Immunol 2015;136:69–80.
  • Zhang XY, Simpson JL, Powell H, Yang IA, Upham JW, Reynolds PN, et al. Full blood count parameters for the detectionof asthma inflammatory phenotypes. Clin Exp Allergy 2014;44:1137–1145.
  • Westerhof GA, Korevaar DA, Amelink M, de Nijs SB, de Groot JC, Wang J, et al. Biomarkers to identify sputum eosinophilia in different adult asthma phenotypes. Eur Respir J 2015;46:688–696.
  • Wu H-C, Delgado-Cruzata L, Flom JD, Kappil M, Ferris JS, Liao Y, et al. Global methylation profiles in DNA from different blood cell types. Epigenetics 2011;6:76–85.
  • Bain BJ. Ethnic and sex differences in the total and differential white cell count and platelet count. J Clin Pathol 1996;49:664–666.

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