Missed opportunities to transition from nebulizers to inhalers during hospitalization for acute asthma: A multicenter observational study

References

• Centers for Disease Control and Prevention. Asthma surveillance data. Available from: http://www.cdc. gov/asthma/asthmadata.htm [accessed 12 December 2016].
   Google Scholar
• Guidelines for the Diagnosis and Management of Asthma (EPR-3). Available from: https://www.nhlbi.nih.gov/health-pro/guidelines/ current/asthma-guidelines [accessed 12 December 2016].
   Google Scholar
• Kamps AW, van Ewik B, Roorda RJ, Brand PL. Poor Inhalation technique, even after inhalation instructions, in children with asthma. Pediatr Pulmonol 2000;39(1):39–42.
   Web of Science ®Google Scholar
• Press VG, Arora VM, Shah LM, Lewis SL, Ivy K, Charbeneau J, et al. Misuse of respiratory inhalers in hospitalized patients with asthma or COPD. J Gen Intern Med 2011;26(6):635–642.
   PubMed Web of Science ®Google Scholar
• Press VG, Arora VM, Trela KC, Adhikari R, Zadravecz FJ, Liao C, et al. Effectiveness of interventions to teach metered-dose and Diskus inhaler techniques. a randomized trial. Ann Am Thorac Soc 2016;13(6):816–824.
   PubMed Web of Science ®Google Scholar
• Raissy HH, Kelly HW. MDI versus nebulizers for acute asthma. J Pediatr Pharmacol Ther 2004;9(4):226–234.
   PubMedGoogle Scholar
• Cates CJ, Welsh EJ, Rowe BH. Holding chambers (spaces) versus nebulisers for beta-agonist treatment of acute asthma. Cochrane Database Syst Rev 2013 September. Available from: http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000052.pub3/full.
   Google Scholar
• Cates C. Spacers and nebulisers for the delivery of beta-agoists in non-life-threatening acute asthma. Respir Med 2003;97(7):762–769.
   PubMed Web of Science ®Google Scholar
• Ploin D, Chapuis FR, Stamm D, Robert J, David L, Chatelain PG, et al. High-dose albuterol by metered-dose inhaler plus a spacer device versus nebulization in preschool children with recurrent wheezing: a double-blind, randomized equivalence trial. Pediatrics 2000;106(2):311–317.
   PubMed Web of Science ®Google Scholar
• Castro-Rodriguez JA, Rodrigo GJ. Beta-agonists through metered-dose inhaler with valved holding chamber versus nebulizer for acute exacerbation of wheezing or asthma in children under 5 years of age: a systematic review with meta-analysis. J Pediatr 2004;145(2):172–177.
   PubMed Web of Science ®Google Scholar
• Kaashmiri M, Shepard J, Goodman B, Lincourt WR, Trivedi R, Ellsworth A, et al. Repeat dosing of albuterol via metered-dose inhaler in infants with acute obstructive airway disease: a randomized controlled safety trial. Pediatr Emerg Care 2010;26(3):197–202.
   PubMed Web of Science ®Google Scholar
• Alhaider SA, Alshehri HA, Al-Eid K. Replacing nebulizers by MDI-spacers for bronchodilator and inhaled corticosteroid administration: Impact on the utilization of hospital resources. Int J Ped Adol Med 2014;1(1):26–30.
   Google Scholar
• Moriates C, Novelero M, Quinn K, Khanna R, Mourad M. “Nebs no more after 24”: a pilot program to improve the use of appropriate respiratory therapies. JAMA Intern Med 2013;173(17):1647–1648.
   PubMed Web of Science ®Google Scholar
• Brand PLP, Roorda RJ. Drug delivery in pediatric patients with asthma: spacer devices vs nebulizers for B2 agonists. Am J Drug Deliv 2003;1(1):61–70.
   Google Scholar
• Melani AS, Canessa P, Coloretti I, DeAngelis G, DeTuillio R, Del Donno M, et al. Inhaler mishandling is very common in patients with chronic airflow obstruction and long-term home nebuliser use. Respir Med 2012;106(5):668–676.
   PubMed Web of Science ®Google Scholar
• Leversha AM, Campanella SG, Aickin RP, Asher MI. Costs and effectiveness of spacer versus nebulizer in young children with moderate and severe acute asthma. J Pediatr 2000;136(4):497–502.
   PubMed Web of Science ®Google Scholar
• Fink JB, Rubin BK. Problems with inhaler use: a call for improved clinician and patient education. Respir Care 2005;50(10):1360–1375.
   PubMedGoogle Scholar
• Emergency Medicine Network. Available from: http://www.emnet-usa.org/ [accessed 1 January 2015].
   Google Scholar
• Hasegawa K, Bittner JC, Nonas SA, Stoll SJ, Watase T, Gabriel S, et al. Children and adults with frequent hospitalizations for asthma exacerbation, 2012–2013: a multicenter observational study. J Allergy Clin Immunol Pract 2015;3(5):751–758.e1.
   PubMed Web of Science ®Google Scholar
• Chandra D, Clark S, Camargo CA, Jr. Race/ethnicity differences in the inpatient management of acute asthma in the United States. Chest 2009;135:1527–1534.
   PubMed Web of Science ®Google Scholar
• Schatz M, Clark S, Camargo CA, Jr. Sex differences in the presentation and course of asthma hospitalizations. Chest 2006;129(1):50–55.
   PubMed Web of Science ®Google Scholar
• Press VG, Arora VM, Shah LM, Lewis SL, Charbeneau J, Naureckas ET, et al. Teaching the use of respiratory inhalers to hospitalized patients with asthma or COPD: a randomized trial. J Gen Intern Med 2012;27(10):1317–1325.
   PubMed Web of Science ®Google Scholar
• Jasper AC, Mohsenifar Z, Kahan S, Goldberg HS, Koerner SK. Cost-benefit comparison of aerosol brohnodilator delivery methods in hospitalized patients. Chest 1987;91(4):614–618.
   PubMed Web of Science ®Google Scholar
• Bowton DL, Goldsmith WM, Haponik EF. Substitution of metered-dose inhalers for hand-held nebulizers. Success and cost savings in a large, acute-care hospital. Chest 1992;101(2):305–308.
   Google Scholar
• Press VG, Pappalardo AA, Conwell WD, Pincavage AT, Prochaska MH, Arora VM. Interventions to improve outcomes for minority adults with asthma: a systematic review. J Gen Intern Med 2012;27(8):1001–1015.
   PubMed Web of Science ®Google Scholar
• Lewis S, Hales S, Slater T, Pearce N, Crane J, Beasley R. Geographical variation in the prevalence of asthma symptoms in New Zealand. N Z Med J 1997 8;110(1049):286–289.
   PubMed Web of Science ®Google Scholar
• Duran-Tauleria E, Rona RJ. Geographical and socioeconomic variation in the prevalence of asthma symptoms in English and Scottish children. Thorax 1999 Jun;54(6):476–481.
   PubMed Web of Science ®Google Scholar
• Moorman JE, Akinbami LJ, Bailey CM, Zahran HS, King ME, Johnson CA, et al. National surveillance of asthma: United States, 2001–2010. Vital Health Stat 2012;3(35):1–58.
   Google Scholar
• Georgopoulos D, Mouloudi E, Kondili E, Klimathianaki M. Bronchodilator delivery with metered-dose inhaler during mechanical ventilation. Crit Care 2000;4(4):227–234.
   PubMed Web of Science ®Google Scholar
• Duarte AG. Inhaled bronchodilator administration during mechanical ventilation. Respir Care 2004;49(6):623–634.
   PubMedGoogle Scholar
• Anderson P. Patient preference for and satisfaction with inhaler devices. Eur Respir Rev 2005;14:109–116.
   Google Scholar
• Chotirmall SH, Watts M, Branagan P, Donegan CF, Moore A, McElvaney NG. Diagnosis and management of asthma in older adults. J Am Geriatr Soc 2009;57(5):901–909.
   PubMed Web of Science ®Google Scholar