The role of serum nuclear factor erythroid 2-related factor 2 in childhood bronchial asthma

References

• Bloom B, Jones LI, Freeman G. Summary health statistics for U.S. children: National Health Interview Survey, 2012. Vital Health Stat 2013; 10:1–81.
   Google Scholar
• Riedl MA, Nel A. Importance of oxidative stress in the pathogenesis and treatment of asthma. CurrOpin Allergy Clin Immunol 2008;8:49–56.
   Web of Science ®Google Scholar
• Nadeem A, Masood A, Siddiqui N. Oxidant-antioxidant imbalance in asthma: scientific, epidemiological data and possible options. Ther Adv Respir Dis 2008;2:215–235.
   PubMedGoogle Scholar
• Dworski R, Han W, Blackwell TS, Hoskins A, Freeman ML. Vitamin E prevents NRF2 suppression by allergens in asthmatic alveolar macrophages in vivo. Free Radic Biol Med 2011;51:516–521.
   PubMed Web of Science ®Google Scholar
• Biswas SK, Rahman I. Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Mol Aspects Med 2009;30:60–76.
   PubMed Web of Science ®Google Scholar
• Cho HY, Kleeberger SR. Noblesse oblige: NRF2 functions in the airways. Am J Respir Cell Mol Biol 2014;50:844–847.
   PubMed Web of Science ®Google Scholar
• Michaeloudes C, Chang PJ, Petrou M, Chung KF. Transforming growth factor-β and nuclear factor E2–related factor 2 regulate antioxidant responses in airway smooth muscle cells: role in asthma. Am J Respir Crit Care Med 2011;184:894–903.
   PubMed Web of Science ®Google Scholar
• Xie JL, Lin MB, Hou Q. [Recent advances in the study of Nrf2 and inflammatory respiratory diseases]. Yao Xue Xue Bao. 2015;50:1080–1087.
   PubMedGoogle Scholar
• Kim J, Cha YN, Surh YJ. A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders. Mutat Res. 2010;690:12–23.
   PubMed Web of Science ®Google Scholar
• Li YJ, Kawada T, Azuma A. Nrf2 is a protective factor against oxidative stresses induced by diesel exhaust particle in allergic asthma. Oxid Med Cell Longev 2013;2013:323607.
   PubMed Web of Science ®Google Scholar
• Li Y, Li GP. Oxidative stress in asthma: a distinct clinical and pathologic feature? J Biol Regul Homeost Agents 2016;30:1053–1057.
   PubMed Web of Science ®Google Scholar
• Global Initiative for Asthma [GINA]. GINA report, global strategy for asthma management and prevention, 2016.
   Google Scholar
• Dondi A, Calamelli E, Piccinno V, Ricci G, Corsini I, Biagi C, Lanari M. Acute asthma in the Pediatric Emergency Department: infections are the main triggers of exacerbations. Biomed Res Int 2017;2017:9687061.
   PubMed Web of Science ®Google Scholar
• Lohman TG, Roche AF, Martorell R. Anthropometric standardization reference manual. Champaign, IL: Human Kinetics Publishers, 1988.
   Google Scholar
• Tanner JM, Miernaux J, Jarman S. Growth and physique studies. In: Weiner JS and Lourie JA, eds. Human biology: a guide to field methods, Oxford, UK: Blackwell Publications; 1969:315–340.
   Google Scholar
• Suttle, NF. Copper deficiency in ruminants; recent developments. Vet Rec 1986;119:519–522.
   PubMed Web of Science ®Google Scholar
• Kraus, RJ and Ganthen HE. Reaction of cyanide with glutathione peroxidase. Biochem Biophys Res Commun 1980;96:1116–1122.
   PubMed Web of Science ®Google Scholar
• Bacharier LB, Guilbert TW. Diagnosis and management of early asthma in preschool-aged children. J Allergy Clin Immunol 2012;130:287–296.
   PubMed Web of Science ®Google Scholar
• Malaquias MAS, Oyama LA, Jericó PC, Costa I, Padilha G, Nagashima S, Lopes-Pacheco M, Rebelatto CLK, Michelotto PV, Xisto DG, Brofman PRS, Rocco PRM, de Noronha L. Effects of mesenchymal stromal cells play a role the oxidant/antioxidant balance in a murine model of asthma. Allergol Immunopathol (Madr) 2018;46:36–143.
   Web of Science ®Google Scholar
• Zedan M, Settin A, Farag M, Ezz-Elregal M, Osman E, Fouda A. Prevalence of bronchial asthma among Egyptian school children. Egyptian J Bronchol 2009;3:124–130.
   Google Scholar
• Comhair SA, Erzurum SC. Redox control of asthma: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal 2010;12:93–124.
   PubMed Web of Science ®Google Scholar
• Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, et al. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med 2005;202:47–59. doi:10.1084/jem.20050538.
   PubMed Web of Science ®Google Scholar
• Ghezzi P. Role of glutathione in immunity and inflammation in the lung. Int J Gen Med 2011;4:105–13.
   PubMedGoogle Scholar
• Wang Z, Zhang H, Sun X, Ren L. The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-β/Smad signaling and activation of the Nrf2/HO-1 pathway. Mol Med Rep 2016;14:2389–2396.
   PubMed Web of Science ®Google Scholar
• Nadeem A, Siddiqui N, Al-Harbi NO, Al-Harbi MM, Ahmad SF. TLR-7 agonist attenuates airway reactivity and inflammation through Nrf2-mediated antioxidant protection in a murine model of allergic asthma. Int J Biochem Cell Biol 2016;73:53–62.
   PubMed Web of Science ®Google Scholar
• Shintani Y, Maruoka S, Gon Y, Koyama D, Yoshida A, Kozu Y, Kuroda K, Takeshita I, Tsuboi E, Soda K, Hashimoto S. Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates airway epithelial barrier integrity. Allergol Int 2015;64:S54–S63.
   PubMed Web of Science ®Google Scholar
• Sussan TE, Gajghate S, Chatterjee S, Mandke P, McCormick S, Sudini K, Kumar S, Breysse PN, Diette GB, Sidhaye VK, Biswal S. Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function. Am J Physiol Lung Cell Mol Physiol 2015;309:L27–L36.
   PubMed Web of Science ®Google Scholar
• Fourtounis J, Wang IM, Mathieu MC, Claveau D, Loo T, Jackson AL, Peters MA, Therien AG, Boie Y, Crackower MA. Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene. Respir Res 2012;13:92.
   PubMed Web of Science ®Google Scholar
• Fitzpatrick AM, Stephenson ST, Hadley GR, Burwell L, Penugonda M, Simon DM, Hansen J, Jones DP, Brown LA. Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. J Allergy Clin Immunol 2011;127:1604–1611.
   PubMed Web of Science ®Google Scholar
• Ahmad A, Shameem M, Husain Q. Relation of oxidant-antioxidant imbalance with disease progression in patients with asthma. Annal Thoracic Med 2012;7:226–232.
   PubMed Web of Science ®Google Scholar
• Yadav AS, Saini M. Evaluation of systemic antioxidant level and oxidative stress in relation to lifestyle and disease progression in asthmatic patients. J Med Biochem 2016;35:55–62.
   PubMed Web of Science ®Google Scholar
• Ben Anes A, Ben Nasr H, Fetoui H, Bchir S, Chahdoura H, Yacoub S, Garrouch A, Benzarti M, Tabka Z, Chahed K. Alteration in systemic markers of oxidative and antioxidative status in Tunisian patients with asthma: relationships with clinical severity and airflow limitation. J Asthma 2016;53:227–237.
   PubMed Web of Science ®Google Scholar
• Hassan SH, Ghani R, Sarwar M. Molecular basi of superoxide dismutase alterations in spirometry proven bronchial asthma. J Pak Med Assoc. 2017;67:1393–1397. https://www.ncbi.nlm.nih.gov/pubmed/?term=Syed+Hafeezul+Hassan%2C+Rubina+Ghani%2CMuhammad+Sarwar.
   PubMed Web of Science ®Google Scholar
• Al-Afaleg NO, Al-Senaidy A, El-Ansary A. Oxidative stress and antioxidant status in Saudi asthmatic patients. Clin Biochem 2011;44:612–617.
   PubMed Web of Science ®Google Scholar