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Therapeutics

Effect of omega-3 fatty acids supplementation during childhood in preventing allergic disease: a systematic review and Meta-Analysis

, MSc, , MD, , MSc, , MSc & , MD, PhD
Pages 523-536 | Received 26 Jul 2019, Accepted 23 Dec 2019, Published online: 10 Jan 2020

References

  • Pawanker R. Allergic diseases and asthma:a global public health concern and a call to action. World Allergy Org J. 2014;7(1):1–3.
  • Pawanker RCG, Holgate ST, Lockey RF, editors. WAO white book on allergy. World Allergy Organization (WAO). 2011. https://www.worldallergy.org/UserFiles/file/WAO-White-Book-on-Allergy_web.pdf.
  • Calder PC, Krauss-Etschmann S, de Jong EC, Dupont C, Frick J-S, Frokiaer H, Heinrich J, Garn H, Koletzko S, Lack G, et al. Early nutrition and immunity: progress and perspectives. Br J Nutr. 2006;96(4):774–790.
  • Macpherson AJ, de Aguero MG, Ganal-Vonarburg SC. How nutrition and the maternal microbiota shape the neonatal immune system. Nat Rev Immunol. 2017;17(8):508–517. doi:10.1038/nri.2017.58.
  • Pham MN, Bunyavanich S. Prenatal diet and the development of childhood allergic diseases: food for thought. Curr Allergy Asthma Rep. 2018;18(11):58. doi:10.1007/s11882-018-0811-9.
  • Browning LM, Walker CG, Mander AP, West AL, Madden J, Gambell JM, Young S, Wang L, Jebb SA, Calder PC, et al. Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish. Am J Clin Nutr. 2012;96(4):748–758. doi:10.3945/ajcn.112.041343.
  • Lochner M, Berod L, Sparwasser T. Fatty acid metabolism in the regulation of T cell function. Trends Immunol. 2015;36(2):81–91. doi:10.1016/j.it.2014.12.005.
  • Calder PC. Functional roles of fatty acids and their effects on human health. JPEN J Parenter Enteral Nutr. 2015;39(1_suppl):18S–32S. doi:10.1177/0148607115595980.
  • Calder PC. Omega-3 fatty acids and inflammatory processes: from molecules to man. Biochem Soc Trans. 2017;45(5):1105–1115. doi:10.1042/BST20160474.
  • Miles EA, Calder PC. Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis. Br J Nutr. 2012;107(S2):S171–S84. doi:10.1017/S0007114512001560.
  • Rodrigues HG, Takeo Sato F, Curi R, Vinolo M. Fatty acids as modulators of neutrophil recruitment, function and survival. Eur J Pharmacol. 2016; 785:50–58. doi:10.1016/j.ejphar.2015.03.098.
  • Prescott SL, Dunstan JA. Prenatal fatty acid status and immune development: the pathways and the evidence. Lipids. 2007;42(9):801–810. doi:10.1007/s11745-007-3030-z.
  • Miles EA, Calder PC. Can early omega-3 fatty acid exposure reduce risk of childhood allergic disease? Nutrients. 2017; 9(7):784. pii: E784. doi:10.3390/nu9070784.
  • Hoppu U, Rinne M, Lampi AM, Isolauri E. Breast milk fatty acid composition is associated with development of atopic dermatitis in the infant. J Pediatr Gastroenterol Nutr. 2005;41(3):335–338. doi:10.1097/01.mpg.0000168992.44428.fa.
  • Rosenlund H, Fagerstedt S, Alm J, Mie A. Breastmilk fatty acids in relation to sensitization: the ALADDIN birth cohort. Allergy. 2016;71(10):1444–1452. doi:10.1111/all.12896.
  • Stoney RM, Woods RK, Hosking CS, Hill DJ, Abramson MJ, Thien FC. Maternal breast milk long-chain n-3 fatty acids are associated with increased risk of atopy in breastfed infants. Clin Exp Allergy. 2004;34(2):194–200. doi:10.1111/j.1365-2222.2004.01852.x.
  • Bisgaard H, Stokholm J, Chawes BL, Vissing NH, Bjarnadóttir E, Schoos A-MM, Wolsk HM, Pedersen TM, Vinding RK, Thorsteinsdóttir S, et al. Fish oil-derived fatty acids in pregnancy and wheeze and asthma in offspring. N Engl J Med. 2016;375(26):2530–2539. doi:10.1056/NEJMoa1503734.
  • Brick T, Schober Y, Böcking C, Pekkanen J, Genuneit J, Loss G, Dalphin J-C, Riedler J, Lauener R, Nockher WA, et al. omega-3 fatty acids contribute to the asthma-protective effect of unprocessed cow’s milk. J Allergy Clin Immunol. 2016;137(6):1699–1706.e13.
  • Magnusson J, Kull I, Westman M, Hakansson N, Wolk A, Melen E, et al. Fish and polyunsaturated fat intake and development of allergic and nonallergic rhinitis. J Allergy Clin Immunol. 2015;136:1247–1253.e1-2. doi:10.1016/j.jaci.2015.05.030.
  • Muley P, Shah M, Muley A. Omega-3 fatty acids supplementation in children to prevent asthma: is it worthy? A systematic review and meta-analysis. J Allergy. 2015; 2015:1–7. doi:10.1155/2015/312052.
  • Kremmyda LS, Vlachava M, Noakes PS, Diaper ND, Miles EA, Calder PC. Atopy risk in infants and children in relation to early exposure to fish, oily fish, or long-chain omega-3 fatty acids: a systematic review. Clinic Rev Allerg Immunol. 2011;41(1):36–66. doi:10.1007/s12016-009-8186-2.
  • Clausen M, Jonasson K, Keil T, Beyer K, Sigurdardottir ST. Fish oil in infancy protects against food allergy in Iceland-Results from a birth cohort study. Allergy. 2018;73(6):1305–1312. doi:10.1111/all.13385.
  • Lapillonne A, Pastor N, Zhuang W, Scalabrin DM. Infants fed formula with added long chain polyunsaturated fatty acids have reduced incidence of respiratory illnesses and diarrhea during the first year of life. BMC Pediatr. 2014;14(1):168. doi:10.1186/1471-2431-14-168.
  • Birch EE, Khoury JC, Berseth CL, Castaneda YS, Couch JM, Bean J, et al. The impact of early nutrition on incidence of allergic manifestations and common respiratory illnesses in children. J Pediatr. 2010; 156:902–906.e1. doi:10.1016/j.jpeds.2010.01.002.
  • D’Vaz N, Meldrum SJ, Dunstan JA, Martino D, McCarthy S, Metcalfe J, et al. Postnatal fish oil supplementation in high-risk infants to prevent allergy: randomized controlled trial. Pediatrics. 2012;130:674–682. doi:10.1542/peds.2011-3104.
  • Foiles AM, Kerling EH, Wick JA, Scalabrin DM, Colombo J, Carlson SE. Formula with long-chain polyunsaturated fatty acids reduces incidence of allergy in early childhood. Pediatr Allergy Immunol. 2016;27(2):156–161. doi:10.1111/pai.12515.
  • Lucas A, Stafford M, Morley R, Abbott R, Stephenson T, MacFadyen U, Elias-Jones A, Clements H. Efficacy and safety of long-chain polyunsaturated fatty acid supplementation of infant-formula milk: a randomised trial. Lancet. 1999;354(9194):1948–1954. doi:10.1016/S0140-6736(99)02314-4.
  • Peat JK, Mihrshahi S, Kemp AS, Marks GB, Tovey ER, Webb K, Mellis CM, Leeder SR. Three-year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study. J Allergy Clin Immunol. 2004;114(4):807–813. doi:10.1016/j.jaci.2004.06.057.
  • Toelle BG, Ng KK, Crisafulli D, Belousova EG, Almqvist C, Webb K, et al. Eight-year outcomes of the Childhood Asthma Prevention Study. J Allergy Clin Immunol. 2010; 126:388–9. doi:10.1016/j.jaci.2010.04.031.
  • Wells G, Shea B, O’Connell J. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Appl Engi Agri. 2014; 18:727–734.
  • Higgins JPT, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JAC, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343(2):d5928–d5928. doi:10.1136/bmj.d5928.
  • Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–560. doi:10.1136/bmj.327.7414.557.
  • Sterne JA, Egger M, Smith GD. Systematic reviews in health care: Investigating and dealing with publication and other biases in meta-analysis. BMJ. 2001;323(7304):101–105. doi:10.1136/bmj.323.7304.101.
  • Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, Norris S, Falck-Ytter Y, Glasziou P, deBeer H, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011;64(4):383–394. doi:10.1016/j.jclinepi.2010.04.026.
  • Khan SJ, Dharmage SC, Matheson MC, Gurrin LC. The atopic march related to confounding by genetics and early life environment? A systematic review of sibship and twin data. Allergy. 2018; 73(1):17–28. doi:10.1111/all.13228.

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