References
- Ma X, Wang L, Liu L, Yang C, Gai Z. Is asthma an exclusionary condition for SARS-CoV-2 infection in China? J Asthma. 2020. doi:https://doi.org/10.1080/02770903.2020.1789873.
- Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, Si HR, Zhu Y, Li B, Huang CL, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270–273. doi:https://doi.org/10.1038/s41586-020-2012-7.
- Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China. JAMA. 2020;323(13):1239. doi:https://doi.org/10.1001/jama.2020.2648.
- Bunyavanich S, Do A, Vicencio A. Nasal gene expression of angiotensin-converting enzyme 2 in children and adults. JAMA. 2020;323(23):2427–2429. doi:https://doi.org/10.1001/jama.2020.8707.
- Pinto BGG, Oliveira AER, Singh Y, Jimenez L, Gonçalves ANA, Ogava RLT, Creighton R, Schatzmann Peron JP, Nakaya HI. ACE2 expression is increased in the lungs of patients with comorbidities associated with severe COVID-19. J Infect Dis. 2020;4:556–563. doi:https://doi.org/10.1093/infdis/jiaa332.
- Jackson DJ, Busse WW, Bacharier LB, Kattan M, O’Connor GT, Wood RA, Visness CM, Durham SR, Larson D, Esnault S, et al. Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2. J Allergy Clin Immunol. 2020;146(1):203–206.e3. doi:https://doi.org/10.1016/j.jaci.2020.04.009.
- Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention 2018. Available from: www.ginaasthma.org
- Carr TF, Zeki AA, Kraft M. Eosinophilic and noneosinophilic asthma. Am J Respir Crit Care Med. 2018;197(1):22–37. doi:https://doi.org/10.1164/rccm.201611-2232PP.
- Alberca-Custodio RW, Faustino LD, Gomes E, Nunes FPB, de Siqueira MK, Labrada A, Almeida RR, Câmara NOS, da Fonseca DM, Russo M. Allergen-specific immunotherapy with liposome containing CpG-ODN in murine model of asthma relies on MyD88 signaling in dendritic cells. Front Immunol. 2020;11:692. doi:https://doi.org/10.3389/fimmu.2020.00692.
- Wenzel SE. Complex phenotypes in asthma: current definitions. Pulm Pharmacol Ther. 2013;26(6):710–715. doi:https://doi.org/10.1016/j.pupt.2013.07.003.
- Zheng R, Wang F, Huang Y, Xiang Q, Dai H, Zhang W. Elevated Th17 cell frequencies and Th17/Treg ratio are associated with airway hyperresponsiveness in asthmatic children. J Asthma. 2020. doi:https://doi.org/10.1080/02770903.2020.1737710.
- Song J, Zeng M, Wang H, Qin C, Hou H, Sun Z, Xu S, Wang G, Guo C, Deng Y, et al. Distinct effects of asthma and COPD comorbidity on disease expression and outcome in patients with COVID‐19. Allergy. 2020. doi:https://doi.org/10.1111/all.14517.
- Kimura H, Francisco D, Conway M, Martinez FD, Vercelli D, Polverino F, Billheimer D, Kraft M. Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells. J Allergy Clin Immunol. 2020;146(1):80–88.e8. doi:https://doi.org/10.1016/j.jaci.2020.05.004.
- Bai J, Smock SL, Jackson GR, MacIsaac KD, Huang Y, Mankus C, Oldach J, Roberts B, Ma YL, Klappenbach JA, et al. Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus. PLoS One. 2015;10(2):e0118286. doi:https://doi.org/10.1371/journal.pone.0118286.
- Al Efraij K, Johnson KM, Wiebe D, Sadatsafavi M, FitzGerald JM. A systematic review of the adverse events and economic impact associated with oral corticosteroids in asthma. J Asthma. 2019;56(12):1334–1346. doi:https://doi.org/10.1080/02770903.2018.1539100.
- Alberca RW, Oliveira L de M, Branco ACCC, Pereira NZ, Sato MN. Obesity as a risk factor for COVID-19: an overview. Crit Rev Food Sci Nutr. 2020. doi:https://doi.org/10.1080/10408398.2020.1775546.
- Nabe T. Steroid-resistant asthma and neutrophils. Biol Pharm Bull. 2020;43(1):31–35. doi:https://doi.org/10.1248/bpb.b19-00095.
- Cowan DC, Cowan JO, Palmay R, Williamson A, Taylor DR. Effects of steroid therapy on inflammatory cell subtypes in asthma. Thorax. 2010;65(5):384–390. doi:https://doi.org/10.1136/thx.2009.126722.
- Prazma CM, Bel EH, Price RG, Bradford ES, Albers FC, Yancey SW. Oral corticosteroid dose changes and impact on peripheral blood eosinophil counts in patients with severe eosinophilic asthma: a post hoc analysis. Respir Res. 2019;20(1):83. doi:https://doi.org/10.1186/s12931-019-1056-4.
- Tien Nguyen L, Lim S, Oates T, Fan Chung ÃK. Increase in airway neutrophils after oral but not inhaled corticosteroid therapy in mild asthma. Respir Med. 2005;99(2):200–207. doi:https://doi.org/10.1016/j.rmed.2004.06.007.
- Ray A, Kolls JK. Neutrophilic inflammation in asthma and association with disease severity. Trends Immunol. 2017;38(12):942–954. doi:https://doi.org/10.1016/j.it.2017.07.003.
- Bruijnzeel PLB, Uddin M, Koenderman L. Targeting neutrophilic inflammation in severe neutrophilic asthma: can we target the disease-relevant neutrophil phenotype? J Leukoc Biol. 2015;98(4):549–556. doi:https://doi.org/10.1189/jlb.3vmr1214-600rr.
- Holgate ST. Trials and tribulations in identifying new biologic treatments for asthma. Trends Immunol. 2012;33(5):238–246. doi:https://doi.org/10.1016/j.it.2012.02.003.