References
- Simpson AJ, Hekking P-P, Shaw DE, Fleming LJ, Roberts G, Riley JH, Bates S, Sousa AR, Bansal AT, Pandis I, et al.; U-BIOPRED Study Group. Treatable traits in the European U-BIOPRED adult asthma cohorts. Allergy 2019;74(2):406–411. doi:https://doi.org/10.1111/all.13629.
- McDonald VM, Fingleton J, Agusti A, Hiles SA, Clark VL, Holland AE, Marks GB, Bardin PP, Beasley R, Pavord ID, et al. Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report. Eur Respir J 2019;53(5):1802058. doi:https://doi.org/10.1183/13993003.02058-2018.
- Robinson DS, Campbell DA, Durham SR, Pfeffer J, Barnes PJ, Chung KF; Asthma and Allergy Research Group of the National Heart and Lung Institute. Systematic assessment of difficult-to-treat asthma. Eur Respir J 2003;22(3):478–483. doi:https://doi.org/10.1183/09031936.03.00017003.
- Clark VL, Gibson PG, Genn G, Hiles SA, Pavord ID, McDonald VM. Multidimensional assessment of severe asthma: a systematic review and meta-analysis. Respirology 2017;22(7):1262–1275. doi:https://doi.org/10.1111/resp.13134.
- Hew M, Menzies-Gow A, Hull JH, Fleming L, Porsbjerg C, Brinke AT, Allen D, Gore R, Tay TR. Systematic assessment of difficult-to-treat asthma: principles and perspectives. J Allergy Clin Immunol Pract 2020;8(7):2222–2233. doi:https://doi.org/10.1016/j.jaip.2020.02.036.
- Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, Adcock IM, Bateman ED, Bel EH, Bleecker ER, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J 2014;43(2):343–373. doi:https://doi.org/10.1183/09031936.00202013.
- Jeimy S, Tsoulis MW, Hachey J, Kim H. Eligibility of monoclonal antibody-based therapy for patients with severe asthma: a Canadian cross-sectional perspective. Allergy Asthma Clin Immunol 2018;14:68. doi:https://doi.org/10.1186/s13223-018-0301-6.
- Contoli M, Ito K, Padovani A, Poletti D, Marku B, Edwards MR, Stanciu LA, Gnesini G, Pastore A, Spanevello A, et al. Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells. Allergy 2015;70(8):910–920. doi:https://doi.org/10.1111/all.12627.
- Juhn YJ. Risks for infection in patients with asthma (or other atopic conditions): is asthma more than a chronic airway disease? J Allergy Clin Immunol 2014;134(2):247–257. quiz 58–59. doi:https://doi.org/10.1016/j.jaci.2014.04.024.
- Nicholas B, Dudley S, Tariq K, Howarth P, Lunn K, Pink S, Sterk PJ, Adcock IM, Monk P, Djukanović R, et al.; U-BIOPRED study group. Susceptibility to influenza virus infection of bronchial biopsies in asthma. J Allergy Clin Immunol 2017;140(1):309–312 e4. doi:https://doi.org/10.1016/j.jaci.2016.12.964.
- Contoli M, Pauletti A, Rossi MR, Spanevello A, Casolari P, Marcellini A, Forini G, Gnesini G, Marku B, Barnes N, et al. Long-term effects of inhaled corticosteroids on sputum bacterial and viral loads in COPD. Eur Respir J 2017;50(4):1700451. doi:https://doi.org/10.1183/13993003.00451-2017.
- Youssef J, Novosad SA, Winthrop KL. Infection risk and safety of corticosteroid use. Rheum Dis Clin North Am 2016;42(1):157–176. ix–x. doi:https://doi.org/10.1016/j.rdc.2015.08.004.
- Padilla-Galo A, Olveira C, Fernández de Rota-Garcia L, Marco-Galve I, Plata AJ, Alvarez A, Rivas-Ruiz F, Carmona-Olveira A, Cebrian-Gallardo JJ, Martinez-Garcia MA, et al. Factors associated with bronchiectasis in patients with uncontrolled asthma; the NOPES score: a study in 398 patients. Respir Res 2018;19(1):43. doi:https://doi.org/10.1186/s12931-018-0746-7.
- Akaba T, Kondo M, Toriyama M, Kubo A, Hara K, Yamada T, Yoshinaga K, Tamaoki J. Common variable immunodeficiency diagnosed during the treatment of bronchial asthma: unusual cause of wheezing. Respir Med Case Rep 2015;16:41–44. doi:https://doi.org/10.1016/j.rmcr.2015.07.002.
- Milota T, Bloomfield M, Parackova Z, Sediva A, Bartunkova J, Horvath R. Bronchial asthma and bronchial hyperresponsiveness and their characteristics in patients with common variable immunodeficiency. Int Arch Allergy Immunol 2019;178(2):192–200. doi:https://doi.org/10.1159/000494128.
- Taylor SL, Leong LEX, Choo JM, Wesselingh S, Yang IA, Upham JW, Reynolds PN, Hodge S, James AL, Jenkins C, et al. Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology. J Allergy Clin Immunol 2018;141(1):94–103. doi:https://doi.org/10.1016/j.jaci.2017.03.044.
- Schär F, Trostdorf U, Giardina F, Khieu V, Muth S, Marti H, Vounatsou P, Odermatt P. Strongyloides stercoralis: global distribution and risk factors. PLoS Negl Trop Dis 2013;7(7):e2288. doi:https://doi.org/10.1371/journal.pntd.0002288.
- Lloyd CM, Snelgrove RJ. Type 2 immunity: expanding our view. Sci Immunol 2018;3(25):eaat1604. doi:https://doi.org/10.1126/sciimmunol.aat1604.
- Buonfrate D, Requena-Mendez A, Angheben A, Muñoz J, Gobbi F, Van Den Ende J, Bisoffi Z. Severe strongyloidiasis: a systematic review of case reports. BMC Infect Dis 2013;13:78. doi:https://doi.org/10.1186/1471-2334-13-78.
- Baker EC, Ming DK, Choudhury Y, Rahman S, Smith PJ, Muñoz J, Chiodini PL, Griffiths CJ, Whitty CJM, Brown M. High prevalence of Strongyloides among south Asian migrants in primary care – associations with eosinophilia and gastrointestinal symptoms. Pathogens 2020;9(2):103. doi:https://doi.org/10.3390/pathogens9020103.
- Biagini RE, Schlottmann SA, Sammons DL, Smith JP, Snawder JC, Striley CAF, MacKenzie BA, Weissman DN. Method for simultaneous measurement of antibodies to 23 pneumococcal capsular polysaccharides. Clin Diagn Lab Immunol 2003;10(5):744–750. doi:https://doi.org/10.1128/cdli.10.5.744-750.2003.
- Browning MJ, Lim MTC, Kenia P, Whittle M, Doffinger R, Barcenas-Morales G, Kumararatne D, Viskaduraki M, O'Callaghan C, Gaillard EA, et al. Pneumococcal polysaccharide vaccine responses are impaired in a subgroup of children with cystic fibrosis. J Cyst Fibros 2014;13(6):632–638. doi:https://doi.org/10.1016/j.jcf.2014.02.002.
- Balmer P, Cant AJ, Borrow R. Anti-pneumococcal antibody titre measurement: what useful information does it yield? J Clin Pathol 2007;60(4):345–350. doi:https://doi.org/10.1136/jcp.2006.041210.
- Orange JS, Ballow M, Stiehm ER, Ballas ZK, Chinen J, De La Morena M, Kumararatne D, Harville TO, Hesterberg P, Koleilat M, et al. Use and interpretation of diagnostic vaccination in primary immunodeficiency: a working group report of the Basic and Clinical Immunology Interest Section of the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol 2012;130(3 Suppl):S1–S24. doi:https://doi.org/10.1016/j.jaci.2012.07.002.
- Buonfrate D, Sequi M, Mejia R, Cimino RO, Krolewiecki AJ, Albonico M, Degani M, Tais S, Angheben A, Requena-Mendez A, et al. Accuracy of five serologic tests for the follow up of Strongyloides stercoralis infection. PLoS Negl Trop Dis 2015;9(2):e0003491. doi:https://doi.org/10.1371/journal.pntd.0003491.
- Hamilos DL, Young RM, Peter JB, Agopian MS, Iklé DN, Barka N. Hypogammaglobulinemia in asthmatic patients. Ann Allergy 1992;68(6):472–481.
- Dupin C, Marchand-Adam S, Favelle O, Costes R, Gatault P, Diot P, Grammatico-Guillon L, Guilleminault L. Asthma and hypogammaglobulinemia: an asthma phenotype with low type 2 inflammation. J Clin Immunol 2016;36(8):810–817. doi:https://doi.org/10.1007/s10875-016-0335-9.
- Kawano T, Matsuse H, Obase Y, Kondo Y, Machida I, Tomari S, Mitsuta K, Fukushima C, Shimoda T, Kohno S, et al. Hypogammaglobulinemia in steroid-dependent asthmatics correlates with the daily dose of oral prednisolone. Int Arch Allergy Immunol 2002;128(3):240–243. doi:https://doi.org/10.1159/000064258.
- Kishiyama JL, Valacer D, Cunningham-Rundles C, Sperber K, Richmond GW, Abramson S, Glovsky M, Stiehm R, Stocks J, Rosenberg L, et al. A multicenter, randomized, double-blind, placebo-controlled trial of high-dose intravenous immunoglobulin for oral corticosteroid-dependent asthma. Clin Immunol 1999;91(2):126–133. doi:https://doi.org/10.1006/clim.1999.4714.
- Salmun LM, Barlan I, Wolf HM, Eibl M, Twarog FJ, Geha RS, Schneider LC. Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: a double-blind, placebo-controlled, randomized trial. J Allergy Clin Immunol 1999;103(5 Part 1):810–815. doi:https://doi.org/10.1016/S0091-6749(99)70424-0.
- Esquivel A, Busse WW, Calatroni A, Togias AG, Grindle KG, Bochkov YA, Gruchalla RS, Kattan M, Kercsmar CM, Khurana Hershey G, et al. Effects of omalizumab on rhinovirus infections, illnesses, and exacerbations of asthma. Am J Respir Crit Care Med 2017;196(8):985–992. doi:https://doi.org/10.1164/rccm.201701-0120OC.
- Klion AD, Nutman TB. The role of eosinophils in host defense against helminth parasites. J Allergy Clin Immunol 2004;113(1):30–37. doi:https://doi.org/10.1016/j.jaci.2003.10.050.
- Keane J, Gershon S, Wise RP, Mirabile-Levens E, Kasznica J, Schwieterman WD, Siegel JN, Braun MM. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 2001;345(15):1098–1104. doi:https://doi.org/10.1056/NEJMoa011110.
- Woolnough KF, Richardson M, Newby C, Craner M, Bourne M, Monteiro W, Siddiqui S, Bradding P, Pashley CH, Wardlaw AJ, et al. The relationship between biomarkers of fungal allergy and lung damage in asthma. Clin Exp Allergy 2017;47(1):48–56. doi:https://doi.org/10.1111/cea.12848.
- Pfeffer PE, Corrigan CJ. An imbalance between proteases and endogenous protease inhibitors in eosinophilic airway disease. Am J Respir Crit Care Med 2017;195(6):707–708. doi:https://doi.org/10.1164/rccm.201610-2020ED.
- Kurt E, Yildirim H, Kiraz N, Orman A, Metintas M, Akgun Y, Erginel S. Oropharyngeal candidiasis with dry-powdered fluticasone propionate: 500 microg/day versus 200 microg/day. Allergol Immunopathol (Madr) 2008;36(1):17–20. doi:https://doi.org/10.1157/13115666.
- Ramachandran S, Shah A, Pant K, Bhagat R, Jaggi OP. Allergic bronchopulmonary aspergillosis and Candida albicans colonization of the respiratory tract in corticosteroid-dependent asthma. Asian Pac J Allergy Immunol 1990;8(2):123–126.
- Naglik JR, Konig A, Hube B, Gaffen SL. Candida albicans–epithelial interactions and induction of mucosal innate immunity. Curr Opin Microbiol 2017;40:104–112. doi:https://doi.org/10.1016/j.mib.2017.10.030.
- Mori A, Ikeda Y, Taniguchi M, Aoyama C, Maeda Y, Hasegawa M, Kobayashi N, Akiyama K. IL-5 production by peripheral blood Th cells of adult asthma patients in response to Candida albicans allergen. Int Arch Allergy Immunol 2001;125 (Suppl 1):48–50. doi:https://doi.org/10.1159/000053853.
- Fukutomi Y, Taniguchi M. Sensitization to fungal allergens: resolved and unresolved issues. Allergol Int 2015;64(4):321–331. doi:https://doi.org/10.1016/j.alit.2015.05.007.
- Wakayama N, Matsune S, Okubo K. Delayed type of allergic skin reaction to Candida albicans in eosinophilic rhinosinusitis cases. Auris Nasus Larynx 2018;45(1):111–115. doi:https://doi.org/10.1016/j.anl.2017.05.009.
- Johnson DC. Chronic candidal bronchitis: a consecutive series. Open Respir Med J 2012;6:145–149. doi:https://doi.org/10.2174/1874306401206010145.
- Schreiber J, Broker BM, Ehmann R, Bachert C. Nonatopic severe asthma might still be atopic: sensitization toward Staphylococcus aureus enterotoxins. J Allergy Clin Immunol 2019;143(6):2279–2280 e2. doi:https://doi.org/10.1016/j.jaci.2019.01.018.