Asthma and COVID-19; different entities, same outcome: a meta-analysis of 107,983 patients

References

• Sohrabi C, Alsafi Z, O’Neill N, Khan M, Kerwan A, Al-Jabir A, Iosifidis C, Agha R. World Health Organization declares global emergency: a review of the 2019 novel coronavirus (COVID-19). Int J Surg. 2020;76:71–76. doi:https://doi.org/10.1016/j.ijsu.2020.02.034.
   PubMed Web of Science ®Google Scholar
• Worldometers. COVID-19 coronavirus pandemic 2020. https://www.worldometers.info/coronavirus/.
   Google Scholar
• Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061. doi:https://doi.org/10.1001/jama.2020.1585.
   PubMed Web of Science ®Google Scholar
• Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–1062. doi:https://doi.org/10.1016/S0140-6736(20)30566-3.
   PubMed Web of Science ®Google Scholar
• Mahdavinia M, Foster KJ, Jauregui E, Moore D, Adnan D, Andy-Nweye AB, Khan S, Bishehsari F. Asthma prolongs intubation in COVID-19. J Allergy Clin Immunol Pract. 2020;8(7):2388–2391. doi:https://doi.org/10.1016/j.jaip.2020.05.006.
   PubMed Web of Science ®Google Scholar
• Zhang J-j, Dong X, Cao Y-y, Yuan Y-d, Yang Y-b, Yan Y-q, Akdis CA, Gao Y-d. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan. China Allergy. 2020;75(7):1730–1741. doi:https://doi.org/10.1111/all.14238.
   PubMed Web of Science ®Google Scholar
• Khawaja AP, Warwick AN, Hysi PG, Kastner A, Dick A, Khaw PT, Tufail A, Foster PJ, Khaw K-T. Associations with covid-19 hospitalisation amongst 406,793 adults: the UK Biobank prospective cohort study. doi:https://doi.org/10.1101/2020.05.06.20092957.
   Google Scholar
• Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults. BMJ. 1993;307(6910):982–986. doi:https://doi.org/10.1136/bmj.307.6910.982.
   PubMed Web of Science ®Google Scholar
• Bizzintino J, Lee W-M, Laing IA, Vang F, Pappas T, Zhang G, Martin AC, Khoo S-K, Cox DW, Geelhoed GC, et al. Association between human rhinovirus C and severity of acute asthma in children. Eur Respir J. 2011;37(5):1037–1042. doi:https://doi.org/10.1183/09031936.00092410.
   PubMed Web of Science ®Google Scholar
• Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, Si H-R, Zhu Y, Li B, Huang C-L, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270–273. doi:https://doi.org/10.1038/s41586-020-2012-7.
   PubMed Web of Science ®Google Scholar
• Camiolo M, Gauthier M, Kaminski N, Ray A, Wenzel SE. Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype. J Allergy Clin Immunol. 2020;146(2):315–324.e7. doi:https://doi.org/10.1016/j.jaci.2020.05.051.
   PubMed Web of Science ®Google Scholar
• Jackson DJ, Busse WW, Bacharier LB, Kattan M, O’Connor GT, Wood RA, et al. Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2. J Allergy Clin Immunol. 2020;146(1):203–206e3. doi:https://doi.org/10.1016/j.jaci.2020.04.009.
   PubMed Web of Science ®Google Scholar
• Kimura H, Francisco D, Conway M, Martinez FD, Vercelli D, Polverino F, et al. Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells. J Allergy Clin Immunol. 2020;146(1):80–88.e8. doi:https://doi.org/10.1016/j.jaci.2020.05.004.
   PubMed Web of Science ®Google Scholar
• Pierce CA, Software review: Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. 2006. Comprehensive meta-analysis (version 2.2.027) [Computer software]. Englewood, NJ: Biostat. Organ Res Methods. 2008;11(1):188–191.
   Web of Science ®Google Scholar
• McInnes MDF, Moher D, Thombs BD, McGrath TA, Bossuyt PM; and the PRISMA-DTA Group, Clifford T, Cohen JF, Deeks JJ, Gatsonis C, Hooft L, et al. Preferred reporting items for a systematic review and meta-analysis of diagnostic test accuracy studies: the PRISMA-DTA statement. JAMA. 2018;319(4):388–396. doi:https://doi.org/10.1001/jama.2017.19163.
   PubMed Web of Science ®Google Scholar
• Garg A, Rout A, Sharma A, Sargsyan D, Tantry U, Gurbel P, et al. Safety and efficacy of antiplatelet regimens after percutaneous coronary intervention using drug eluting stents: a network meta-analysis of randomized controlled trials. Prog Cardiovasc Dis. 2020;63(3):243–28. doi:https://doi.org/10.1016/j.pcad.2020.03.018.
   PubMed Web of Science ®Google Scholar
• DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177–188. doi:https://doi.org/10.1016/0197-2456(86)90046-2.
   PubMedGoogle Scholar
• Barroso B, Valverde-Monge M, Cañas Jose A, Rodrigo- Muñoz JM, Gonzalez-Cano B, Villalobos-Violan V, Betancor D, Gomez-Cardeñosa A, Vallejo-Chamorro G, Baptista-Serna L, COVID-FJD TEAM, et al. Presenting prevalence, characteristics and outcome of asthmatic patients with T2 diseases in hospitalized subjects with COVID-19 in Madrid, Spain. J Investig Allergol Clin Immunol. 2020;30(5):382–384. doi:https://doi.org/10.18176/jiaci.0627.
   PubMed Web of Science ®Google Scholar
• Chhiba KD, Patel GB, Vu THT, Chen MM, Guo A, Kudlaty E, Mai Q, Yeh C, Muhammad LN, Harris KE, et al. Prevalence and characterization of asthma in hospitalized and nonhospitalized patients with COVID-19. J Allergy Clin Immunol. 2020;146(2):307–314 e4. doi:https://doi.org/10.1016/j.jaci.2020.06.010.
   PubMed Web of Science ®Google Scholar
• Dreher M, Kersten A, Bickenbach J, Balfanz P, Hartmann B, Cornelissen C, Daher A, Stöhr R, Kleines M, Lemmen SW, et al. The characteristics of 50 hospitalized COVID-19 patients with and without ARDS. Dtsch Arztebl Int. 2020;117(16):271–278. doi:https://doi.org/10.3238/arztebl.2020.0271.
   PubMed Web of Science ®Google Scholar
• Giannouchos TV, Sussman RA, Mier JM, Poulas K, Farsalinos K. Characteristics and risk factors for COVID-19 diagnosis and adverse outcomes in Mexico: an analysis of 89,756 laboratory–confirmed COVID-19 cases. Eur Respir J. 2020;2002144. doi:https://doi.org/10.1183/13993003.02144-2020.
   Web of Science ®Google Scholar
• Goyal P, Choi JJ, Pinheiro LC, Schenck EJ, Chen R, Jabri A, Satlin MJ, Campion TR, Nahid M, Ringel JB, et al. Clinical characteristics of Covid-19 in New York City. N Engl J Med. 2020;382(24):2372–2374. doi:https://doi.org/10.1056/NEJMc2010419.
   PubMed Web of Science ®Google Scholar
• Grandbastien M, Piotin A, Godet J, Abessolo-Amougou I, Ederlé C, Enache I, Fraisse P, Tu Hoang TC, Kassegne L, Labani A, et al. SARS-CoV-2 pneumonia in hospitalized asthmatic patients did not induce severe exacerbation. J Allergy Clin Immunol Pract. 2020;8(8):2600–2607. doi:https://doi.org/10.1016/j.jaip.2020.06.032.
   PubMed Web of Science ®Google Scholar
• Lieberman-Cribbin W, Rapp J, Alpert N, Tuminello S, Taioli E. The impact of asthma on mortality in patients with COVID-19. Chest. 2020;158(6):2290–2291. doi:https://doi.org/10.1016/j.chest.2020.05.575.
   PubMed Web of Science ®Google Scholar
• Nguyen AB, Upadhyay GA, Chung B, Smith B, Besser SA, Johnson JA, et al. Outcomes and cardiovascular comorbidities in a predominantly African-American population with COVID-19. medRxiv. 2020. doi:https://doi.org/10.1101/2020.06.28.20141929.
   Google Scholar
• Wang A-L, Zhong X, Hurd Y. Comorbidity and sociodemographic determinants in COVID-19 mortality in an US Urban Healthcare System. medRxiv. 2020. doi:https://doi.org/10.1101/2020.06.11.20128926.
   Google Scholar
• Hussein MH, Toraih EA, Attia AS, Burley N, Zhang AD, Roos J, Houghton A, Aniemeka N, Omar M, Aboueisha M, et al. Asthma in COVID-19: an extra chain fitting around the neck? Respir Med. 2020;175:106205. doi:https://doi.org/10.1016/j.rmed.2020.106205.
   PubMed Web of Science ®Google Scholar
• Qiu H, Tong Z, Ma P, Hu M, Peng Z, Wu W, Du B, China Critical Care Clinical Trials Group (CCCCTG). Intensive care during the coronavirus epidemic. Intensive Care Med. 2020;46(4):576–578. doi:https://doi.org/10.1007/s00134-020-05966-y.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Most recent national asthma data. Available from: https://www.cdc.gov/asthma/most_recent_national_asthma_data.htm. Accessed July 9, 2020.
   Google Scholar
• CDC.gov. 2018. Centers for Disease Control and Prevention. Asthma: most recent asthma data. [online]. Available at: https://www.cdc.gov/asthma/most_recent_data.htm. Accessed July 7. 2020.
   Google Scholar
• Peters U, Dixon AE, Forno E. Obesity and asthma. J Allergy Clin Immunol. 2018;141(4):1169–1179. doi:https://doi.org/10.1016/j.jaci.2018.02.004.
   PubMed Web of Science ®Google Scholar
• Sutherland ER. Obesity and asthma. Immunol Allergy Clin North Am. 2008;28(3):589–602. doi:https://doi.org/10.1016/j.iac.2008.03.003.
   PubMed Web of Science ®Google Scholar
• Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB, et al. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol. 2005;79(23):14614–14621. doi:https://doi.org/10.1128/JVI.79.23.14614-14621.2005.
   PubMed Web of Science ®Google Scholar
• Higham A, Singh D. Increased ACE2 expression in the bronchial epithelium of COPD patients who are overweight. Obesity (Silver Spring). 2020;28(9):1586–1589. doi:https://doi.org/10.1002/oby.22907.
   PubMed Web of Science ®Google Scholar