Non-adherence and sub-optimal treatment with asthma medications in young adults: a population-based cohort study

References

• Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. 2020 [accessed 2020 Jun]. https://ginasthma.org/wp-content/uploads/2020/06/GINA-2020-report_20_06_04-1-wms.pdf
   Google Scholar
• Reddel HK, Busse WW, Pedersen S, Tan WC, Chen YZ, Jorup C, Lythgoe D, O’Byrne PM. Should recommendations about starting inhaled corticosteroid treatment for mild asthma be based on symptom frequency: a post-hoc efficacy analysis of the START study. Lancet. 2017;389(10065):157–166.
   PubMed Web of Science ®Google Scholar
• Reddel HK, Ampon RD, Sawyer SM, Peters MJ. Risks associated with managing asthma without a preventer: urgent healthcare, poor asthma control and over-the-counter reliever use in a cross-sectional population survey. BMJ Open. 2017;7(9):e016688.
   PubMed Web of Science ®Google Scholar
• O’Byrne PM, FitzGerald JM, Bateman ED, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Ivanov S, Reddel HK. Inhaled combined budesonide-formoterol as needed in mild asthma. N Engl J Med. 2018;378(20):1865–1876.
   PubMed Web of Science ®Google Scholar
• Bateman ED, Reddel HK, O’Byrne PM, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Siwek-Posluszna A, FitzGerald JM. As-needed budesonide-formoterol versus maintenance budesonide in mild asthma. N Engl J Med. 2018;378(20):1877–1887.
   PubMed Web of Science ®Google Scholar
• Nwaru BI, Ekström M, Hasvold P, Wiklund F, Telg G, Janson C. Overuse of short-acting β. Eur Respir J. 2020;55(4):1901872.
   PubMed Web of Science ®Google Scholar
• Murphy J, McSharry J, Hynes L, Matthews S, Van Rhoon L, Molloy GJ. Prevalence and predictors of adherence to inhaled corticosteroids in young adults (15-30 years) with asthma: a systematic review and meta-analysis. J Asthma. 2020;58(5):683–705.
   PubMed Web of Science ®Google Scholar
• Desai M, Oppenheimer JJ. Medication adherence in the asthmatic child and adolescent. Curr Allergy Asthma Rep. 2011;11(6):454–464.
   PubMed Web of Science ®Google Scholar
• World Health Organization. Adherence to long-term therapies: evidens for action. Geneva (Switzerland): WGO; 2003 [accessed 2020 Jun]. https://www.who.int/chp/knowledge/publications/adherence_full_report.pdf.
   Google Scholar
• Peláez S, Lamontagne AJ, Collin J, Gauthier A, Grad RM, Blais L, Lavoie KL, Bacon SL, Ernst P, Guay H, et al. Patients’ perspective of barriers and facilitators to taking long-term controller medication for asthma: a novel taxonomy. BMC Pulm Med. 2015;15:42.
   PubMed Web of Science ®Google Scholar
• Dahlén E, Komen J, Jonsson EW, Almqvist C, Kull I, Wettermark B. Eliminated patient fee and changes in dispensing patterns of asthma medication in ­children—an interrupted time series analysis. Basic Clin Pharmacol Toxicol. 2019;125(4):360–369.
   PubMed Web of Science ®Google Scholar
• Øymar K, Mikalsen IB, Furu K, Nystad W, Karlstad Ø. Prescription patterns of inhaled corticosteroids for preschool children—a Norwegian register study. Pediatr Allergy Immunol. 2015;26(7):655–661.
   PubMed Web of Science ®Google Scholar
• Roberts G, Vazquez-Ortiz M, Knibb R, Khaleva E, Alviani C, Angier E, Blumchen K, Comberiati P, Duca B, DunnGalvin A, et al. EAACI guideline on the effective transition of adolescents and young adults with allergy and asthma. Allergy. 2020;75(11):2734–2752.
   PubMed Web of Science ®Google Scholar
• Ödling M, Andersson N, Hallberg J, Almqvist C, Janson C, Bergström A, Melén E, Kull I. A gap between asthma guidelines and management for adolescents and young adults. J Allergy Clin Immunol Pract. 2020;8(9):3056–3065.e2.
   PubMed Web of Science ®Google Scholar
• Wang L, Palmer AJ, Otahal P, Cocker F, Sanderson K. Multimorbidity and health care service utilization in the Australian workforce: findings from the National Health Survey. J Occup Environ Med. 2017;59(8):795–802.
   PubMed Web of Science ®Google Scholar
• Wickman M, Kull I, Pershagen G, Nordvall SL. The BAMSE project: presentation of a prospective longitudinal birth cohort study. Pediatr Allergy Immunol. 2002;13(s15):11–13.
   PubMedGoogle Scholar
• Melén E, Bergström A, Kull I, Almqvist C, Andersson N, Asarnoj A, Borres MP, Georgellis A, Pershagen G, Westman M, et al. Male sex is strongly associated with IgE-sensitization to airborne but not food allergens: results up to age 24 years from the BAMSE birth cohort. Clin Transl Allergy. 2020;10:15.
   PubMed Web of Science ®Google Scholar
• Wang G, Hallberg J, Um Bergström P, Janson C, Pershagen G, Gruzieva O, van Hage M, Georgelis A, Bergström A, Kull I, et al. Assessment of chronic bronchitis and risk factors in young adults: results from BAMSE. Eur Respir J. 2020;57(3):2002120.
   Web of Science ®Google Scholar
• Wettermark B, Hammar N, Fored CM, MichaelFored C, Leimanis A, Olausson PO, Persson I, Sundström A, Westerholm B, Rosén M. The new Swedish Prescribed Drug Register–opportunities for pharmacoepidemiological research and experience from the first six months. Pharmacoepidemiol Drug Saf. 2007;16(7):726–735.
   PubMed Web of Science ®Google Scholar
• Wallerstedt SM, Wettermark B, Hoffmann M. The first decade with the Swedish Prescribed Drug Register—a systematic review of the output in the scientific literature. Basic Clin Pharmacol Toxicol. 2016;119(5):464–469.
   PubMed Web of Science ®Google Scholar
• Eriksson I, Cars T, Piehl F, Malmström RE, Wettermark B, von Euler M. Persistence with dimethyl fumarate in relapsing-remitting multiple sclerosis: a population-based cohort study. Eur J Clin Pharmacol. 2018;74(2):219–226.
   PubMed Web of Science ®Google Scholar
• Forslund T, Wettermark B, Hjemdahl P. Comparison of treatment persistence with different oral anticoagulants in patients with atrial fibrillation. Eur J Clin Pharmacol. 2016;72(3):329–338.
   PubMed Web of Science ®Google Scholar
• Zarrinkoub R, Wettermark B, Wändell P, Mejhert M, Szulkin R, Ljunggren G, Kahan T. The epidemiology of heart failure, based on data for 2.1 million inhabitants in Sweden. Eur J Heart Fail. 2013;15(9):995–1002.
   PubMed Web of Science ®Google Scholar
• Cramer JA, Roy A, Burrell A, Fairchild CJ, Fuldeore MJ, Ollendorf DA, Wong PK. Medication compliance and persistence: terminology and definitions. Value Health. 2008;11(1):44–47.
   PubMed Web of Science ®Google Scholar
• Dahlén E, Ekberg S, Lundholm C, Jonsson EW, Kull I, Wettermark B, Almqvist C. Sibship and dispensing patterns of asthma medication in young children-a population-based study. Pharmacoepidemiol Drug Saf. 2019;28(8):1109–1116.
   PubMed Web of Science ®Google Scholar
• WHO Collaborating Center for Drug Statistics Methodology, Oslo. Guidelines for ATC classification and DDD assignment; 2021 [accessed 2021 Jan]. https://www.whocc.no/filearchive/publications/2021_guidelines_web.pdf
   Google Scholar
• Shlomi D, Katz I, Segel MJ, Oberman B, Peled N. Determination of asthma control using administrative data regarding short-acting beta-agonist inhaler purchase. J Asthma. 2018;55(5):571–577.
   PubMed Web of Science ®Google Scholar
• O’Byrne PM, Reddel HK, Beasley R. The management of mild asthma. Eur Respir J. 2020:2003051.
   Google Scholar
• Kaye L, Theye B, Smeenk I, Gondalia R, Barrett MA, Stempel DA. Changes in medication adherence among patients with asthma and COPD during the COVID-19 pandemic. J Allergy Clin Immunol Pract. 2020;8(7):2384–2385.
   PubMed Web of Science ®Google Scholar
• Ödling M, Jonsson M, Janson C, Melén E, Bergström A, Kull I. Lost in the transition from pediatric to adult healthcare? Experiences of young adults with severe asthma. J Asthma. 2019;57(10):1119–1127.
   PubMed Web of Science ®Google Scholar
• Örtqvist AK, Lundholm C, Wettermark B, Ludvigsson JF, Ye W, Almqvist C. Validation of asthma and eczema in population-based Swedish drug and patient registers. Pharmacoepidemiol Drug Saf. 2013;22(8):850–860.
   PubMed Web of Science ®Google Scholar
• Vrijens B, Dima AL, Van Ganse E, van Boven JF, Eakin MN, Foster JM, de Bruin M, Chisholm A, Price D. What we mean when we talk about adherence in respiratory medicine. J Allergy Clin Immunol Pract. 2016;4(5):802–812.
   PubMed Web of Science ®Google Scholar