Disease burden and treatment adherence among children and adolescent patients with asthma

References

• Ferrante G, La Grutta S. The burden of pediatric asthma. Front Pediatr. 2018;6:186. doi:https://doi.org/10.3389/fped.2018.00186.
   PubMed Web of Science ®Google Scholar
• Serebrisky D, Wiznia A. Pediatric asthma: a global epidemic. Ann Glob Health. 2019;85(1):6. doi:https://doi.org/10.5334/aogh.2416.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Most recent national asthma data. 2019. https://www.cdc.gov/asthma/most_recent_national_asthma_data.htm.
   Google Scholar
• Perry R, Braileanu G, Palmer T, Stevens P. The economic burden of pediatric asthma in the United States: literature review of current evidence. Pharmacoeconomics. 2019;37(2):155–167. doi:https://doi.org/10.1007/s40273-018-0726-2.
   PubMed Web of Science ®Google Scholar
• Desai M, Oppenheimer JJ. Medication adherence in the asthmatic child and adolescent. Curr Allergy Asthma Rep. 2011;11(6):454–464. doi:https://doi.org/10.1007/s11882-011-0227-2.
   PubMed Web of Science ®Google Scholar
• Lang A, Mowinckel P, Sachs-Olsen C, Riiser A, Lunde J, Carlsen K-H, Lødrup Carlsen KC. Asthma severity in childhood, untangling clinical phenotypes. Pediatr Allergy Immunol. 2010;21(6):945–953. doi:https://doi.org/10.1111/j.1399-3038.2010.01072.x.
   PubMed Web of Science ®Google Scholar
• Oliver BG, Robinson P, Peters M, Black J. Viral infections and asthma: an inflammatory interface? Eur Respir J. 2014;44(6):1666–1681. doi:https://doi.org/10.1183/09031936.00047714.
   PubMed Web of Science ®Google Scholar
• National Asthma Education and Prevention Program, Third expert panel on the diagnosis and management of asthma. Expert panel report 3: guidelines for the diagnosis and management of asthma. Bethesda (MD): National Heart, Lung, and Blood Institute (US); 2007. pp. 1–278, 326–328.
   Google Scholar
• Kaplan A, Hardjojo A, Yu S, Price D. Asthma across age: insights from primary care. Front Pediatr. 2019;7:162. doi:https://doi.org/10.3389/fped.2019.00162.
   PubMed Web of Science ®Google Scholar
• Ortiz-Alvarez O, Mikrogianakis A, Canadian Paediatric Society, Acute Care Committee. Managing the paediatric patient with an acute asthma exacerbation. Paediatr Child Health. 2012;17(5):251–262. doi:https://doi.org/10.1093/pch/17.5.251.
   PubMed Web of Science ®Google Scholar
• Trivedi M, Denton E. Asthma in children and adults-what are the differences and what can they tell us about asthma? Front Pediatr. 2019;7:256. doi:https://doi.org/10.3389/fped.2019.00256.
   PubMed Web of Science ®Google Scholar
• Kaplan A, Price D. Treatment adherence in adolescents with asthma. J Asthma Allergy. 2020;13:39–49. doi:https://doi.org/10.2147/JAA.S233268.
   PubMed Web of Science ®Google Scholar
• Stanford RH, Averell C, Parker ED, Blauer-Peterson C, Reinsch TK, Buikema AR. Assessment of adherence and asthma medication ratio (AMR) for a once-daily and twice-daily inhaled corticosteroid/long acting beta agonist (ICS/LABA) for asthma. J Allergy Clin Immunol Pract. 2019;7(5):1488–1496.e7. doi:https://doi.org/10.1016/j.jaip.2018.12.021.
   PubMed Web of Science ®Google Scholar
• Averell CM, Stanford RH, Laliberté F, Wu JW, Germain G, Duh MS. Medication adherence in patients with asthma using once-daily versus twice-daily ICS/LABAs. J Asthma. 2021;58(1):102–111. doi:https://doi.org/10.1080/02770903.2019.1663429.
   PubMed Web of Science ®Google Scholar
• Wu AC, Butler MG, Li L, Fung V, Kharbanda EO, Larkin EK, Vollmer WM, Miroshnik I, Davis RL, Lieu TA, et al. Primary adherence to controller medications for asthma is poor. Ann Am Thorac Soc. 2015;12(2):161–166. doi:https://doi.org/10.1513/AnnalsATS.201410-459OC.
   PubMed Web of Science ®Google Scholar
• Marckmann M, Hermansen MN, Hansen KS, Chawes BL. Assessment of adherence to asthma controllers in children and adolescents. Pediatr Allergy Immunol. 2020;31(8):930–937. doi:https://doi.org/10.1111/pai.13312.
   PubMed Web of Science ®Google Scholar
• Burgess S, Sly P, Devadason S. Adherence with preventive medication in childhood asthma. Pulm Med. 2011;2011:973849. doi:https://doi.org/10.1155/2011/973849.
   PubMedGoogle Scholar
• Engelkes M, Janssens HM, de Jongste JC, Sturkenboom MC, Verhamme KM. Medication adherence and the risk of severe asthma exacerbations: a systematic review. Eur Respir J. 2015;45(2):396–407. doi:https://doi.org/10.1183/09031936.00075614.
   PubMed Web of Science ®Google Scholar
• Rehman N, Morais-Almeida M, Wu AC. Asthma across childhood: improving adherence to asthma management from early childhood to adolescence. J Allergy Clin Immunol Pract. 2020;8(6):1802–1807.e1. doi:https://doi.org/10.1016/j.jaip.2020.02.011.
   PubMed Web of Science ®Google Scholar
• Morton RW, Everard ML, Elphick HE. Adherence in childhood asthma: the elephant in the room. Arch Dis Child. 2014;99(10):949–953. doi:https://doi.org/10.1136/archdischild-2014-306243.
   PubMed Web of Science ®Google Scholar
• Boutopoulou B, Koumpagioti D, Matziou V, Priftis KN, Douros K. Interventions on adherence to treatment in children with severe asthma: a systematic review. Front Pediatr. 2018;6:232. doi:https://doi.org/10.3389/fped.2018.00232.
   PubMed Web of Science ®Google Scholar
• Chipps BE, Bacharier LB, Farrar JR, Jackson DJ, Murphy KR, Phipatanakul W, Szefler SJ, Teague WG, Zeiger RS. The pediatric asthma yardstick: practical recommendations for a sustained step-up in asthma therapy for children with inadequately controlled asthma. Ann Allergy Asthma Immunol. 2018;120(6):559–579.e11. doi:https://doi.org/10.1016/j.anai.2018.04.002.
   PubMed Web of Science ®Google Scholar
• Martinez FD, Chinchilli VM, Morgan WJ, Boehmer SJ, Lemanske RF, Mauger DT, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, et al. Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial. Lancet. 2011;377(9766):650–657. doi:https://doi.org/10.1016/S0140-6736(10)62145-9.
   PubMed Web of Science ®Google Scholar
• Lemanske RF, Jr, Mauger DT, Sorkness CA, Jackson DJ, Boehmer SJ, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, et al. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med. 2010;362(11):975–985. doi:https://doi.org/10.1056/NEJMoa1001278.
   PubMed Web of Science ®Google Scholar
• Chipps BE, Zeiger RS, Borish L, Wenzel SE, Yegin A, Hayden ML, Miller DP, Bleecker ER, Simons FER, Szefler SJ, et al. Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. J Allergy Clin Immunol. 2012;130(2):332–342.e10. doi:https://doi.org/10.1016/j.jaci.2012.04.014.
   PubMed Web of Science ®Google Scholar
• Bacharier LB, Strunk RC, Mauger D, White D, Lemanske RF, Jr, Sorkness CA. Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function. Am J Respir Crit Care Med. 2004;170(4):426–432. doi:https://doi.org/10.1164/rccm.200308-1178OC.
   PubMed Web of Science ®Google Scholar
• Delea TE, Stanford RH, Hagiwara M, Stempel DA. Association between adherence with fixed dose combination fluticasone propionate/salmeterol on asthma outcomes and costs. Curr Med Res Opin. 2008;24(12):3435–3442. doi:https://doi.org/10.1185/03007990802557344.
   PubMed Web of Science ®Google Scholar
• Ismaila A, Corriveau D, Vaillancourt J, Parsons D, Stanford R, Su Z, Sampalis JS. Impact of adherence to treatment with fluticasone propionate/salmeterol in asthma patients. Curr Med Res Opin. 2014;30(7):1417–1425. doi:https://doi.org/10.1185/03007995.2014.908827.
   PubMed Web of Science ®Google Scholar