458
Views
1
CrossRef citations to date
0
Altmetric
Articles

Otitis media in severe asthma associated with chronic rhinosinusitis with nasal polyps: a new therapeutic target for biologics

, MDORCID Icon, , MD, PhD, , MD, , MD, PhD, , MD, , MD, , MD, PhD, , MD, PhD & , MD, PhD show all
Pages 139-144 | Received 03 Nov 2021, Accepted 20 Jan 2022, Published online: 03 Feb 2022

References

  • Daval M, Picard H, Bequignon E, Bedbeder P, Coste A, Ayache D, Escabasse V. Chronic otitis media with effusion in chronic sinusitis with polyps. Ear Nose Throat J. 2018;97(8):E13–E18. doi:10.1177/014556131809700803.
  • Ciprandi G, Torretta S, Marseglia GL, Licari A, Chiappini E, Benazzo M, Tosca MA, Marchisio P. Allergy and otitis media in clinical practice. Curr Allergy Asthma Rep. 2020;20(8):33 doi:10.1007/s11882-020-00930-8.
  • Parietti-Winkler C, Baumann C, Gallet P, Gauchard G, Jankowski R. Otitis media with effusion as a marker of the inflammatory process associated to nasal polyposis. Rhinology. 2009;47(4):396–399. doi:10.4193/Rhin08.220.
  • Iino Y, Tomioka-Matsutani S, Matsubara A, Nakagawa T, Nonaka M. Diagnostic criteria of eosinophilic otitis media, a newly recognized middle ear disease. Auris Nasus Larynx. 2011;38(4):456–461. doi:10.1016/j.anl.2010.11.016.
  • Bachert C, Zhang N, Cavaliere C, Weiping W, Gevaert E, Krysko O. Biologics for chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2020;145(3):725–739. doi:10.1016/j.jaci.2020.01.020.
  • Kagoshima H, Hori R, Kojima T, Okanoue Y, Taguchi A, Yamamoto H, Hasebe K, Shoji K. Successful treatment of eosinophilic chronic rhinosinusitis and eosinophilic otitis media using the anti-IL-5 receptor monoclonal antibody benralizumab: a case report. Respir Med Case Rep. 2020;30:101135. doi:10.1016/j.rmcr.2020.101135.
  • van der Lans RJL, van Spronsen E, Fokkens WJ, Reitsma S. Complete remission of severe eosinophilic otitis media with dupilumab: a case report. Laryngoscope. 2021;131(12):2649–2651. doi:10.1002/lary.29730.
  • Gevaert P, Omachi TA, Corren J, Mullol J, Han J, Lee SE, Kaufman D, Ligueros-Saylan M, Howard M, Zhu R, et al. Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials. J Allergy Clin Immunol. 2020;146(3):595–605. doi:10.1016/j.jaci.2020.05.032.
  • Bachert C, Han JK, Desrosiers M, Hellings PW, Amin N, Lee SE, Mullol J, Greos LS, Bosso JV, Laidlaw TM, et al. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet. 2019;394(10209):1638–1650. doi:10.1016/S0140-6736(19)31881-1.
  • Bachert C, Han JK, Desrosiers MY, Gevaert P, Heffler E, Hopkins C, et al. Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: a randomized, placebo-controlled trial. J Allergy Clin Immunol. 2021;S0091-6749(21):01459.
  • Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, Adcock IM, Bateman ED, Bel EH, Bleecker ER, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J. 2014;43(2):343–373. doi:10.1183/09031936.00202013.
  • Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reltsma S, Mullol J, Bachert C, Alobid I, Baroody F, et al. European position paper on rhinosinusitis and nasal polyps. Rhinology. 2020;29:1–464.
  • Numata T, Miyagawa H, Nishioka S, Okuda K, Utsumi H, Hashimoto M, Minagawa S, Ishikawa T, Hara H, Araya J, et al. Efficacy of benralizumab for patients with severe eosinophilic asthma: a retrospective, real-life study. BMC Pulm Med. 2020;20(1):207. doi:10.1186/s12890-020-01248-x.
  • Humbert M, Beasley R, Ayres J, Slavin R, Hébert J, Bousquet J, Beeh K-M, Ramos S, Canonica GW, Hedgecock S, et al. Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE. Allergy. 2005;60(3):309–316. doi:10.1111/j.1398-9995.2004.00772.x.
  • Dupin C, Belhadi D, Guilleminault L, Gamez A‐S, Berger P, De Blay F, Bonniaud P, Leroyer C, Mahay G, Girodet P‐O, et al. Effectiveness and safety of dupilumab for the treatment of severe asthma in a real-life French multi-centre adult cohort. Clin Exp Allergy. 2020;50(7):789–798. doi:10.1111/cea.13614.
  • Iino Y, Takahashi E, Ida S, Kikuchi S. Clinical efficacy of anti-IL-5 monoclonal antibody mepolizumab in the treatment of eosinophilic otitis media. Auris Nasus Larynx. 2019;46(2):196–203. doi:10.1016/j.anl.2018.07.011.
  • Eger K, Kroes JA, Ten Brinke A, Bel EH. Long-term therapy response to anti-IL-5 biologics in severe asthma-a real-life evaluation. J Allergy Clin Immunol Pract. 2021;9(3):1194–1200. doi:10.1016/j.jaip.2020.10.010.
  • Parietti-Winkler C, Jankowski R. Is there an association between otitis media and nasal polyposis? Curr Allergy Asthma Rep. 2011;11(6):521–525. doi:10.1007/s11882-011-0229-0.
  • Seo Y, Nonaka M, Pawankar R. Eosinophilic otitis media and comorbid asthma. Curr Opin Allergy Clin Immunol. 2020;20(1):9–13. doi:10.1097/ACI.0000000000000589.
  • Hamada S, Ogino E, Yasuba H. Cycling therapy with benralizumab and dupilumab for severe eosinophilic asthma with eosinophilic chronic rhinosinusitis and eosinophilic otitis media. Allergol Int. 2021;70(3):389–391. doi:10.1016/j.alit.2021.02.002.
  • Chow K, Cosetti MK. Use of IL-5 inhibitor benralizumab as a novel therapy for eosinophilic otitis media: clinical capsule and review of literature. Otol Neurotol. 2020;41(2):e238–e240. doi:10.1097/MAO.0000000000002493.
  • Passali D, Passali GC, Lauriello M, Romano A, Bellussi L, Passali FM. Nasal allergy and otitis media: a real correlation? Sultan Qaboos Univ Med J. 2014;14(1):e59-64–64. doi:10.12816/0003337.
  • Kanazawa H, Yoshida N, Yamamoto H, Hara M, Hasegawa M, Matsuzawa S, Shinnabe A, Iino Y. Risk factors associated with severity of eosinophilic otitis media. Auris Nasus Larynx. 2014;41(6):513–517. doi:10.1016/j.anl.2014.08.003.
  • Ohta N, Ishida A, Kurakami K, Suzuki Y, Kakehata S, Ono J, Ikeda H, Okubo K, Izuhara K. Expressions and roles of periostin in otolaryngological diseases. Allergol Int. 2014;63(2):171–180. doi:10.2332/allergolint.13-RAI-0673.
  • Miura T, Matsubara A, Kudo N, Hara R, Takahata J, Sasaki A. The expression of thymic stromal lymphopoietin in patients and animal models with eosinophilic otitis media. Acta Otolaryngol. 2018;138(5):447–451. doi:10.1080/00016489.2017.1416170.
  • Lloyd A, Turk F, Leighton T, Canonica GW. Psychometric evaluation of global evaluation of treatment effectiveness: a tool to assess patients with moderate-to-severe allergic asthma. J Med Econ. 2007;10(3):285–296. doi:10.3111/13696990701478856.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.