The impact of the clip-tone training device and its smartphone application to pressurized metered-dose inhaler in adult asthmatics

References

• Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, Abbasi-Kangevari M, Abbastabar H, Abd-Allah F, Abdelalim A, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. 2020;396(10258):1204–1222. doi:10.1016/S0140-6736(20)30925-9.
   PubMed Web of Science ®Google Scholar
• Asthma GIf. Global strategy for asthma management and prevention. Curr Opin Pulm Med. 2020.
   Google Scholar
• Abdelrahman MA, Saeed H, Osama H, Harb HS, Madney YM, Abdelrahim MEA. Effect of verbal counselling on metred‐dose inhaler proper use and lung function test amongst asthmatic patients: A meta‐analysis. Int J Clin Pract. 2021;75(6):e14077. doi:10.1111/ijcp.14077.
   PubMed Web of Science ®Google Scholar
• Hanania NA, Braman S, Adams SG, Adewuya R, Ari A, Brooks Jann, Mahler DA, Ohar JA, Peters J, Sanjar S, et al. The role of inhalation delivery devices in COPD: perspectives of patients and health care providers. Chronic Obstr Pulm Dis. 2018;5(2):111–123.
   PubMed Web of Science ®Google Scholar
• Alismail A, Song CA, Terry MH, Daher N, Almutairi WA, Lo T. Diverse inhaler devices: a big challenge for health-care professionals. Respiratory Care. 2016;61(5):593–599. doi:10.4187/respcare.04293.
   PubMed Web of Science ®Google Scholar
• Price DB, Román-Rodríguez M, McQueen RB, Bosnic-Anticevich S, Carter V, Gruffydd-Jones K, Haughney J, Henrichsen S, Hutton C, Infantino A, et al. Inhaler errors in the CRITIKAL study: type, frequency, and association with asthma outcomes. J Allergy Clin Immunol Pract. 2017;5(4):1071–1081.e9.
   PubMed Web of Science ®Google Scholar
• Cho-Reyes S, Celli BR, Dembek C, Yeh K, Navaie M. Inhalation technique errors with metered-dose inhalers among patients with obstructive lung diseases: a systematic review and meta-analysis of US studies. Chron Obstruct Pulm Dis. 2019;6(3):267–280. doi:10.15326/jcopdf.6.3.2018.0168.
   PubMed Web of Science ®Google Scholar
• Sanchis J, Gich I, Pedersen S, Aerosol Drug Management Improvement Team (ADMIT). Systematic review of errors in inhaler use: has patient technique improved over time? Chest. 2016;150(2):394–406. doi:10.1016/j.chest.2016.03.041.
   PubMed Web of Science ®Google Scholar
• Newman SP, Morén F, Pavia D, Corrado O, Clarke SW. The effects of changes in metered volume and propellant vapour pressure on the deposition of pressurized inhalation aerosols. Int J Pharm. 1982;11(4):337–344. doi:10.1016/0378-5173(82)90084-9.
   Web of Science ®Google Scholar
• Hindle M, Newton D, Chrystyn H. Investigations of an optimal inhaler technique with the use of urinary salbutamol excretion as a measure of relative bioavailability to the lung. Thorax. 1993;48(6):607–610. doi:10.1136/thx.48.6.607.
   PubMed Web of Science ®Google Scholar
• Usmani OS, Hindle M, Newton D, Chrystyn H, Effects of bronchodilator particle size in asthmatic. Am J Respir Crit Care Med. 2005;172(6):656–657.
   PubMed Web of Science ®Google Scholar
• Harb HS, Ibrahim Laz N, Rabea H, Abdelrahim MEA. Real-life assessment of chronic obstructive pulmonary disease patient performance with different inhalers. Int J Clin Pract. 2021;75(4):e13905. doi:10.1111/ijcp.13905.
   PubMed Web of Science ®Google Scholar
• Harb HS, Ibrahim Laz N, Rabea H, Abdelrahim MEA. Determinants of incorrect inhaler technique in chronic obstructive pulmonary disease patients. Int J Clin Pract. 2021;75(6):e14073. doi:10.1111/ijcp.14073.
   PubMed Web of Science ®Google Scholar
• Harb HS, Laz NI, Rabea H, Abdelrahim MEA. First-time handling of different inhalers by chronic obstructive lung disease patients. Exp Lung Res. 2020;46(7):258–269. doi:10.1080/01902148.2020.1789903.
   PubMed Web of Science ®Google Scholar
• Harb HS, Laz NI, Rabea H, Abdelrahim MEA. Prevalence and predictors of suboptimal peak inspiratory flow rate in COPD patients. Eur J Pharm Sci. 2020;147:105298. doi:10.1016/j.ejps.2020.105298.
   PubMed Web of Science ®Google Scholar
• Howard S, Lang A, Sharples S, Shaw D. See I told you I was taking it! - Attitudes of adolescents with asthma towards a device monitoring their inhaler use: Implications for future design. Appl Ergon. 2017;58:224–237. doi:10.1016/j.apergo.2016.06.018.
   PubMed Web of Science ®Google Scholar
• Elgendy MO, Hassan AH, Saeed H, Abdelrahim ME, Eldin RS. Asthmatic children and MDI verbal inhalation technique counseling. Pulm Pharmacol Ther. 2020;61:101900. doi:10.1016/j.pupt.2020.101900.
   PubMed Web of Science ®Google Scholar
• Elgendy MO, Abdelrahim ME, Eldin RS. Potential benefit of repeated MDI inhalation technique counselling for patients with asthma. Eur J Hosp Pharm. 2015;22(6):318–322. doi:10.1136/ejhpharm-2015-000648.
   Google Scholar
• Saji M, Alhas J, Siraj S. Study on the impact of patient counseling on the quality of life and pulmonary function of asthmatic patient. Int J Pharm Pharm Sci. 2012;4(Suppl 5):300–304.
   Google Scholar
• Shareef J, Kripa G, Baikunje S. Impact of pharmacists’ counseling on quality of life in patients undergoing hemodialysis in a tertiary care teaching hospital. World J Nephrol Urol. 2014;3(4):143–150. doi:10.14740/wjnu188w.
   Google Scholar
• Ovchinikova L, Smith L, Bosnic-Anticevich S. Inhaler technique maintenance: gaining an understanding from the patient’s perspective. J Asthma. 2011;48(6):616–624. doi:10.3109/02770903.2011.580032.
   PubMed Web of Science ®Google Scholar
• www.nationaljewish.org. Metered-Dose Inhaler technique; 2021. https://www.nationaljewish.org/conditions/medications/asthma-medications/devices/metered-dose.
   Google Scholar
• Trivedi D. Interventions to improve inhaler technique for people with asthma. Prim Health Care Res Dev. 2019;20. doi:10.1017/S1463423619000501.
   Web of Science ®Google Scholar
• Welch M, Greiner A, Smith S, Ostrom N, Sanders M. Training tool versus instruction leaflet for pMDI use-A controlled group comparative study. Eur Respiratory Soc. 2015;46:PA1236. doi:10.1183/13993003.congress-2015.PA1236.
   Google Scholar
• Román-Rodríguez M, Metting E, Gacía-Pardo M, Kocks J, van der Molen T. Wrong inhalation technique is associated to poor asthma clinical outcomes. Is there room for improvement? Curr Opin Pulm Med. 2019;25(1):18–26. doi:10.1097/MCP.0000000000000540.
   PubMed Web of Science ®Google Scholar
• Sanders M, Johnson R, Young P, Duke DJ, Honnery D, Tran C. Understanding flow rate influence on clip-tone guided inhaler delivery. In Drug Delivery to the Lungs Conference 2019. 2020.
   Google Scholar
• World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. Jama. 2013;310(20):2191–2194.
   PubMed Web of Science ®Google Scholar
• Laube BL, Janssens HM, de Jongh FHC, Devadason SG, Dhand R, Diot P, Everard ML, Horvath I, Navalesi P, Voshaar T, International Society for Aerosols in Medicine, et al. What the pulmonary specialist should know about the new inhalation therapies. Eur Respir J. 2011;37(6):1308–1417., doi:10.1183/09031936.00166410.
   PubMed Web of Science ®Google Scholar
• Saeed H, Abdelrahim ME, Rabea H, Salem HF. Impact of advanced patient counseling using a training device and smartphone application on asthma control. Respir Care. 2020;65(3):326–332. doi:10.4187/respcare.06903.
   PubMed Web of Science ®Google Scholar
• Saeed H, Salem HF, Rabea H, Abdelrahim MEA. Effect of human error, inhalation flow, and inhalation volume on dose delivery from Ellipta® dry-powder inhaler. J Pharm Innov. 2019;14(3):239–244. doi:10.1007/s12247-018-9352-y.
   Web of Science ®Google Scholar
• Schatz M, Sorkness CA, Li JT, Marcus P, Murray JJ, Nathan RA, Kosinski M, Pendergraft TB, Jhingran P. Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. J Allerg Clin Immunol. 2006;117(3):549–556. doi:10.1016/j.jaci.2006.01.011.
   PubMed Web of Science ®Google Scholar
• Schatz M, Kosinski M, Yarlas AS, Hanlon J, Watson ME, Jhingran P. The minimally important difference of the Asthma Control Test. J Allergy Clin Immunol. 2009;124(4):719–723.e1. doi:10.1016/j.jaci.2009.06.053.
   PubMed Web of Science ®Google Scholar
• Nguyen VN, Chavannes N, Tuyet Le LT, Price D. The Asthma Control Test (ACT) as an alternative tool to Global Initiative for Asthma (GINA) guideline criteria for assessing asthma control in Vietnamese outpatients. Primary Care Respir J. 2011;21(1):85–89. doi:10.4104/pcrj.2011.00093.
   Google Scholar
• Nicola M, Elberry AA, Sayed OM, Hussein RRS, Abdelrahim MEA. Effect of DPI’s training-device on inhalation technique and clinical efficacy in asthmatics. Beni-Suef Univ J Basic Appl Sci. 2018;7(2):178–183. doi:10.1016/j.bjbas.2017.10.005.
   Google Scholar
• Ammari WG, Chrystyn H. Optimizing the inhalation flow and technique through metered dose inhalers of asthmatic adults and children attending a community pharmacy. J Asthma. 2013;50(5):505–513. doi:10.3109/02770903.2013.783064.
   PubMed Web of Science ®Google Scholar
• Kocks JWH, Chrystyn H, van der Palen J, Thomas M, Yates L, Landis SH, Driessen MT, Gokhale M, Sharma R, Molimard M, et al. Systematic review of association between critical errors in inhalation and health outcomes in asthma and COPD. NPJ Prim Care Resp Med. 2018;28(1):1–6. doi:10.1038/s41533-018-0110-x.
   PubMed Web of Science ®Google Scholar