Plasma levels of oxysterols 7-ketocholesterol and cholestane-3β, 5α, 6β-triol in patients with allergic asthma

References

• Global Initiative for Asthma, Global strategy for asthma management and prevention. Fontana, USA, 2021. https://ginasthma.org/gina-reports.
   Google Scholar
• Backman H, Räisänen P, Hedman L, Stridsman C, Andersson M, Lindberg A, Lundbäck B, Rönmark E. Increased prevalence of allergic asthma from 1996 to 2006 and further to 2016-results from three population surveys. Clin Exp Allergy. 2017;47(11):1426–1435. doi:10.1111/cea.12963.
   PubMed Web of Science ®Google Scholar
• Mathur SK, Viswanathan RK. Relevance of allergy in adult asthma. Curr Allergy Asthma Rep. 2014 May;14(5):437. doi:10.1007/s11882-014-0437-5.
   PubMed Web of Science ®Google Scholar
• Michaeloudes C, Abubakar-Waziri H, Lakhdar R, Raby K, Dixey P, Adcock IM, Mumby S, Bhavsar PK, Chung KF. Molecular mechanisms of oxidative stress in asthma. Mol Aspects Med. 2021:101026. (published online ahead of print). doi:10.1016/j.mam.2021.101026.
   PubMed Web of Science ®Google Scholar
• Zuo L, Koozechian MS, Chen LL. Characterization of reactive nitrogen species in allergic asthma. Ann Allergy Asthma Immunol. 2014;112(1):18–22. doi:10.1016/j.anai.2013.10.007.
   PubMed Web of Science ®Google Scholar
• Sahiner UM, Birben E, Erzurum S, Sackesen C, Kalayci Ö. Oxidative stress in asthma: part of the puzzle. Pediatr Allergy Immunol. 2018;29(8):789–800. doi:10.1111/pai.12965.
   PubMed Web of Science ®Google Scholar
• van der Vliet A, Janssen-Heininger YMW, Anathy V. Oxidative stress in chronic lung disease: from mitochondrial dysfunction to dysregulated redox signaling. Mol Aspects Med. 2018;63:59–69. doi:10.1016/j.mam.2018.08.001.
   PubMed Web of Science ®Google Scholar
• Qu J, Li Y, Zhong W, Gao P, Hu C. Recent developments in the role of reactive oxygen species in allergic asthma. J Thorac Dis. 2017;9(1):E32–E43. doi:10. 21037/jtd.2017.01.05.
   PubMed Web of Science ®Google Scholar
• Jesenak M, Zelieskova M, Babusikova E. Oxidative stress and bronchial asthma in children-causes or consequences? Front Pediatr. 2017;5:162. doi:10.3389/fped.2017.00162.
   PubMed Web of Science ®Google Scholar
• Aldakheel FM, Thomas PS, Bourke JE, Matheson MC, Dharmage SC, Lowe AJ. Relationships between adult asthma and oxidative stress markers and pH in exhaled breath condensate: a systematic review. Allergy. 2016;71(6):741–757. doi:10.1111/all.12865.
   PubMed Web of Science ®Google Scholar
• Karadogan B, Beyaz S, Gelincik A, Buyukozturk S, Arda N. Evaluation of oxidative stress biomarkers and antioxidant parameters in allergic asthma patients with different level of asthma control. J Asthma. 2021;8:1–15. doi:10.1080/02770903.2020.1870129. Epub ahead of print.
   Web of Science ®Google Scholar
• Gaschler MM, Stockwell BR. Lipid peroxidation in cell death. Biochem Biophys Res Commun. 2017;482(3):419–425. doi:10.1016/j.bbrc.2016.10.086.
   PubMed Web of Science ®Google Scholar
• Thomas CE, Aust SD. Free radicals and environmental toxins. Ann Emerg Med. 1986;15(9):1075–1083. doi:10.1016/S0196-0644(86)80132-9.
   PubMed Web of Science ®Google Scholar
• Su L-J, Zhang J-H, Gomez H, Murugan R, Hong X, Xu D, Jiang F, Peng Z-Y. Reactive oxygen species-induced lipid peroxidation in apoptosis, autophagy, and ferroptosis. Oxid Med Cell Longev. 2019;2019:5080843. doi:10.1155/2019/5080843.
   PubMed Web of Science ®Google Scholar
• Nixon M, Andrew R. Oxysterols as therapeutic targets. Br J Pharmacol. 2021;178(16):3085–3088. doi:10.1111/bph.15577.
   PubMed Web of Science ®Google Scholar
• Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ, Pendergraft TB. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol. 2004;113(1):59–65. doi:10.1016/j.jaci.2003.09.008.
   PubMed Web of Science ®Google Scholar
• Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol. 1978;52:302–310. doi:10.1016/s0076-6879(78)52032-6.
   PubMedGoogle Scholar
• Esterbauer H, Cheeseman KH. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 1990;186:407–421. doi:10.1016/0076-6879(90)86134-h.
   PubMed Web of Science ®Google Scholar
• Jiang X, Ory DS, Han X. Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine. Rapid Commun Mass Spectrom. 2007;21(2):141–152. doi:10.1002/rcm.2820.
   PubMed Web of Science ®Google Scholar
• Cho YS, Moon HB. The role of oxidative stress in the pathogenesis of asthma. Allergy Asthma Immunol Res. 2010;2(3):183–187. doi:10.4168/aair.2010.2.3.183.
   PubMed Web of Science ®Google Scholar
• Fernando Y, Wickramasinghe P, De Silva U, Alahakoon M, Anuradha KW, Handunnetti S. Differences in serum markers of oxidative stress in well controlled and poorly controlled asthma in Sri Lankan children: a pilot study. Allergy Asthma Clin Immunol. 2020;16(1):1–9. doi:10.1186/s13223-020-00463-9.
   PubMed Web of Science ®Google Scholar
• Sahiner UM, Birben E, Erzurum S, Sackesen C, Kalayci O. Oxidative stress in asthma. World Allergy Organ J. 2011;4(10):151–158. doi:10.1097/WOX.0b013e318232389e.
   PubMedGoogle Scholar
• Nadeem A, Chhabra SK, Masood A, Raj HG. Increased oxidative stress and altered levels of antioxidants in asthma. J Allergy Clin Immunol. 2003;111(1):72–78. doi:10.1067/mai.2003.17.
   PubMed Web of Science ®Google Scholar
• Marrocco I, Altieri F, Peluso I. Measurement and clinical significance of biomarkers of oxidative stress in humans. Oxid Med Cell Longev. 2017;2017:6501046. doi:10.1155/2017/6501046.
   PubMed Web of Science ®Google Scholar
• Ayala A, Muñoz MF, Argüelles S. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev. 2014;2014:360438. doi:10.1155/2014/360438.
   PubMed Web of Science ®Google Scholar
• Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR, Grandjean P. Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem. 1997;43(7):1209–1214.
   PubMed Web of Science ®Google Scholar
• Khoubnasabjafari M, Ansarin K, Jouyban A. Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders. Bioimpacts. 2015;5(3):123–127. doi:10.15171/bi.2015.20.
   PubMed Web of Science ®Google Scholar
• Abboud MM, Al-Rawashde FA, Al-Zayadneh EM. Alterations of serum and saliva oxidative markers in patients with bronchial asthma. J Asthma. 2021;6:1–8. doi:10.1080/02770903.2021.2008426.
   Web of Science ®Google Scholar
• Brown AJ, Sharpe LJ, Rogers MJ. Oxysterols: from physiological tuners to pharmacological opportunities. Br J Pharmacol. 2021;178(16):3089–3103. doi:10.1111/bph.15073.
   PubMed Web of Science ®Google Scholar
• Samadi A, Sabuncuoglu S, Samadi M, Isikhan SY, Chirumbolo S, Peana M, Lay I, Yalcinkaya A, Bjørklund G. A comprehensive review on oxysterols and related diseases. Curr Med Chem. 2021;28(1):110–136. doi:10.2174/0929867327666200316142659.
   PubMed Web of Science ®Google Scholar
• Aksu N, Samadi A, Yalçınkaya A, Çetin T, Eser B, Lay İ, Öziş TN, Öztaş Y, Sabuncuoğlu S. Evaluation of oxysterol levels of patients with silicosis by LC-MS/MS method. Mol Cell Biochem. 2020;467(1–2):117–125. doi:10.1007/s11010-020-03706-w.
   PubMed Web of Science ®Google Scholar
• Poli G, Biasi F, Leonarduzzi G. Oxysterols in the pathogenesis of major chronic diseases. Redox Biol. 2013;1(1):125–130. doi:10.1016/j.redox.2012.12.001.
   PubMed Web of Science ®Google Scholar
• Bargagli E, Olivieri C, Bennett D, Prasse A, Muller-Quernheim J, Rottoli P. Oxidative stress in the pathogenesis of diffuse lung diseases: a review. Respir Med. 2009;103(9):1245–1256. doi:10.1016/j.rmed.2009.04.014.
   PubMed Web of Science ®Google Scholar
• Samadi A, Gurlek A, Sendur SN, Karahan S, Akbiyik F, Lay I. Oxysterol species: reliable markers of oxidative stress in diabetes mellitus. J Endocrinol Invest. 2019;42(1):7–17. doi:10.1007/s40618-018-0873-5.
   PubMed Web of Science ®Google Scholar
• Leoni V, Caccia C. Oxysterols as biomarkers in neurodegenerative diseases. Chem Phys Lipids. 2011;164(6):515–524. doi:10.1016/j.chemphyslip.2011.04.002.
   PubMed Web of Science ®Google Scholar
• Choi C, Finlay DK. Diverse immunoregulatory roles of oxysterols-the oxidized cholesterol metabolites. Metabolites. 2020;10(10):384. doi:10.3390/metabo10100384.
   PubMed Web of Science ®Google Scholar
• Li WJ, Zhao Y, Gao Y, Dong LL, Wu YF, Chen ZH, Shen HH. Lipid metabolism in asthma: immune regulation and potential therapeutic target. Cell Immunol. 2021;364:104341. doi:10.1016/j.cellimm.2021.104341.
   PubMed Web of Science ®Google Scholar
• Rascu A, Arghir OC, Naghi E, Otelea MR. Serum aminotransferases and the severity of asthma. Rev Chim. 2018;69(5):1200–1202. doi:10.37358/RC.18.5.6255.
   Web of Science ®Google Scholar
• Zhao L, Lei W, Deng C, Wu Z, Sun M, Jin Z, Song Y, Yang Z, Jiang S, Shen M, et al. The roles of liver X receptor α in inflammation and inflammation-associated diseases. J Cell Physiol. 2021;236(7):4807–4828. doi:10.1002/jcp.30204.
   PubMed Web of Science ®Google Scholar
• Heine G, Dahten A, Hilt K, Ernst D, Milovanovic M, Hartmann B, Worm M. Liver X receptors control IgE expression in B cells. J Immunol. 2009;182(9):5276–5282. doi:10.4049/jimmunol.0801804.
   PubMed Web of Science ®Google Scholar
• Zhang J, Wu Z, Yu F, Ye L, Gu W, Tan Y, Wang L, Shi Y. Role of liver-X-receptors in airway remodeling in mice with chronic allergic asthma. Exp Ther Med. 2021;22(3):920. doi:10.3892/etm.2021.10352.
   PubMed Web of Science ®Google Scholar
• Vejux A, Lizard G. Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis. Mol Aspects Med. 2009;30(3):153–170. doi:10.1016/j.mam.2009.02.006.
   PubMed Web of Science ®Google Scholar
• Sanchez LD, Pontini L, Marinozzi M, Sanchez-Aranguren LC, Reis A, Dias IHK. Cholesterol and oxysterol sulfates: pathophysiological roles and analytical challenges. Br J Pharmacol. 2021;178(16):3327–3341. doi:10.1111/bph.15227. PMID: 32762060.
   PubMed Web of Science ®Google Scholar
• Ghio AJ. Asthma as a disruption in iron homeostasis. Biometals. 2016;29(5):751–779. doi:10.1007/s10534-016-9948-y.
   PubMed Web of Science ®Google Scholar