The impact of multistrains of probiotics on Th17-related cytokines in patients with asthma: a randomized, double-blind, placebo-controlled trial

References

• Samimi LN, Fallahpour M, Khoshmirsafa M, Moosavi SAJ, Bayati P, Baharlou R, Falak R. The impact of 17β-estradiol and progesterone therapy on peripheral blood mononuclear cells of asthmatic patients. Mol Biol Rep 2021;48(1):297–306. doi:10.1007/s11033-020-06046-6
   PubMed Web of Science ®Google Scholar
• Ahmadi-Vasmehjani A, Baharlou R, Atashzar MR, Raofi R, Jafari M, Razavi F-S. Regulatory effects of estradiol on peripheral blood mononuclear cells activation in patients with asthma. Iranian J Allergy Asthma Immunol 2018;17(1):9–17.
   PubMed Web of Science ®Google Scholar
• Kim H-J, Kim HY, Lee S-Y, Seo J-H, Lee E, Hong S-J. Clinical efficacy and mechanism of probiotics in allergic diseases. Korean J Pediatr 2013;56(9):369. doi:10.3345/kjp.2013.56.9.369
   PubMedGoogle Scholar
• Pfefferle PI, Keber CU, Cohen RM, Garn H. The hygiene hypothesis–learning from but not living in the past. Front Immunol 2021;12:632. doi:10.3389/fimmu.2021.635935
   Web of Science ®Google Scholar
• Racke MK, Bonomo A, Scott DE, Cannella B, Levine A, Raine CS, Shevach EM, Röcken M. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J Exp Med 1994;180(5):1961–1966. doi:10.1084/jem.180.5.1961
   PubMed Web of Science ®Google Scholar
• Yuan Y, Yang B, Ye Z, Zhang M, Yang X, Xin C, Lin M, Huang P. Sceptridium ternatum extract exerts antiasthmatic effects by regulating Th1/Th2 balance and the expression levels of leukotriene receptors in a mouse asthma model. J Ethnopharmacol 2013;149(3):701–706. doi:10.1016/j.jep.2013.07.032
   PubMed Web of Science ®Google Scholar
• Liu AH. Revisiting the hygiene hypothesis for allergy and asthma. J Allergy Clin Immunol 2015;136(4):860–865. doi:10.1016/j.jaci.2015.08.012
   PubMed Web of Science ®Google Scholar
• Kim NY, Ji GE. Effects of probiotics on the prevention of atopic dermatitis. Korean J Pediat 2012;55(6):193. doi:10.3345/kjp.2012.55.6.193
   PubMedGoogle Scholar
• JadidiNiaragh F, Mirshafiey A. Th17 cell, the new player of neuroinflammatory process in multiple sclerosis. Scand J Immunol 2011;74(1):1–13. doi:10.1111/j.1365-3083.2011.02536.x
   PubMed Web of Science ®Google Scholar
• Eustace A, Smyth LJ, Mitchell L, Williamson K, Plumb J, Singh D. Identification of cells expressing IL-17A and IL-17F in the lungs of patients with COPD. Chest 2011;139(5):1089–1100. doi:10.1378/chest.10-0779
   PubMed Web of Science ®Google Scholar
• Yang CH, Tian JJ, Ko WS, Shih CJ, Chiou YL. Oligo‑fucoidan improved unbalance the Th1/Th2 and Treg/Th17 ratios in asthmatic patients: an ex vivo study. Exp Thera Med 2019;17(1):3–10.
   PubMed Web of Science ®Google Scholar
• Williams NT. Probiotics. Am J Health-System Pharm 2010;67(6):449–458. doi:10.2146/ajhp090168
   PubMed Web of Science ®Google Scholar
• Gourbeyre P, Denery S, Bodinier M. Probiotics, prebiotics, and synbiotics: impact on the gut immune system and allergic reactions. J Leukocyte Biol 2011;89(5):685–695. doi:10.1189/jlb.1109753
   PubMed Web of Science ®Google Scholar
• Petersen C, Round JL. Defining dysbiosis and its influence on host immunity and disease. Cellular Microbiol 2014;16(7):1024–1033. doi:10.1111/cmi.12308
   PubMed Web of Science ®Google Scholar
• Oelschlaeger TA. Mechanisms of probiotic actions – a review. Int J Med Microbiol 2010;300(1):57–62. doi:10.1016/j.ijmm.2009.08.005
   PubMed Web of Science ®Google Scholar
• Liu M-Y, Yang Z-Y, Dai W-K, Huang J-Q, Li Y-H, Zhang J, Qiu CZ, Wei C, Zhou Q, Sun X, et al. Protective effect of Bifidobacterium infantis CGMCC313-2 on ovalbumin-induced airway asthma and β-lactoglobulin-induced intestinal food allergy mouse models. World J Gastroenterol 2017;23(12):2149. doi:10.3748/wjg.v23.i12.2149
   PubMed Web of Science ®Google Scholar
• Del Giudice MM, Maiello N, Allegorico A, Iavarazzo L, Capasso M, Capristo C, Ciprandi G. Lactobacillus reuteri DSM 17938 plus vitamin D3 as ancillary treatment in allergic children with asthma. Ann Allergy Asthma Immunol 2016;117(6):710–712. doi:10.1016/j.anai.2016.09.004
   PubMed Web of Science ®Google Scholar
• Ranu H, Wilde M, Madden B. Pulmonary function tests. Ulster Med J 2011;80(2):84.
   PubMedGoogle Scholar
• Nguyen THT, Casale TB. Immune modulation for treatment of allergic disease. Immunol Rev 2011;242(1):258–271. doi:10.1111/j.1600-065X.2011.01034.x
   PubMed Web of Science ®Google Scholar
• Bedada TL, Feto TK, Awoke KS, Garedew AD, Yifat FT, Birri DJ. Probiotics for cancer alternative prevention and treatment. Biomed Pharmacother 2020;129:110409. doi:10.1016/j.biopha.2020.110409
   PubMed Web of Science ®Google Scholar
• Hajavi J, Esmaeili SA, Varasteh AR, Vazini H, Atabati H, Mardani F, Momtazi-Borojeni AA, Hashemi M, Sankian M, Sahebkar A. The immunomodulatory role of probiotics in allergy therapy. J Cell Physiol 2019;234(3):2386–2398. doi:10.1002/jcp.27263
   PubMed Web of Science ®Google Scholar
• Tirone C, Pezza L, Paladini A, Tana M, Aurilia C, Lio A, D’Ippolito S, Tersigni C, Posteraro B, Sanguinetti M, et al. Gut and lung microbiota in preterm infants: immunological modulation and implication in neonatal outcomes. Front Immunol 2019;10:2910. doi:10.3389/fimmu.2019.02910
   PubMed Web of Science ®Google Scholar
• Marsland BJ, Trompette A, Gollwitzer ES. The gut–lung axis in respiratory disease. Ann Am Thoracic Soc 2015;12(Supplement 2):S150–S156. doi:10.1513/AnnalsATS.201503-133AW
   PubMed Web of Science ®Google Scholar
• Liu A, Ma T, Xu N, Jin H, Zhao F, Kwok L-Y, Zhang H, Zhang S, Sun Z. Adjunctive probiotics alleviates asthmatic symptoms via modulating the gut microbiome and serum metabolome. Microbiol Spectr 2021;9(2):e00859-21. doi:10.1128/Spectrum.00859-21
   PubMed Web of Science ®Google Scholar
• Stockert K, Schneider B, Porenta G, Rath R, Nissel H, Eichler I. Laser acupuncture and probiotics in school age children with asthma: a randomized, placebo‐controlled pilot study of therapy guided by principles of Traditional Chinese Medicine. Pediatr Allergy Immunol 2007;18(2):160–166. doi:10.1111/j.1399-3038.2006.00493.x
   PubMed Web of Science ®Google Scholar
• Moura JCV, Moura ICG, Gaspar GR, Mendes GMS, Faria BAV, Jentzsch NS, do Carmo Friche Passos M, Kurdi A, Godman B, Almeida AM. The use of probiotics as a supplementary therapy in the treatment of patients with asthma: a pilot study and implications. Clinics 2019;74:e950. doi:10.6061/clinics/2019/e950
   PubMed Web of Science ®Google Scholar
• Boulet L-P. Irreversible airway obstruction in asthma. Curr Allergy Asthma Rep 2009;9(2):168–173. doi:10.1007/s11882-009-0025-2
   PubMed Web of Science ®Google Scholar
• Mazzarella G, Bianco A, Catena E, De Palma R, Abbate G. Th1/Th2 lymphocyte polarization in asthma. Allergy 2000;55(suppl 61):6–9. doi:10.1034/j.1398-9995.2000.00511.x
   PubMed Web of Science ®Google Scholar
• Gao M, Liu LX, Wu FL, Zhang X, Li YY, Shi T, Li DZ, Han TT. The changes of Th17/Treg and related cytokines: IL-17, IL-23, IL-10, and TGF-β in respiratory syncytial virus bronchiolitis rat model. Iran J Allergy Asthma Immunol 2017;16(5):386–395.
   PubMed Web of Science ®Google Scholar
• Looman KIM, van Meel ER, Grosserichter-Wagener C, Vissers FJM, Klingenberg JH, de Jong NW, de Jongste JC, Pasmans SGMA, Duijts L, van Zelm MC, et al. Associations of Th2, Th17, Treg cells, and IgA(+) memory B cells with atopic disease in children: the generation R study. Allergy 2020;75(1):178–187. doi:10.1111/all.14010
   PubMed Web of Science ®Google Scholar
• Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of TH17 cells. Nature 2008;453(7198):1051–1057. doi:10.1038/nature07036
   PubMed Web of Science ®Google Scholar
• Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006;24(2):179–189. doi:10.1016/j.immuni.2006.01.001
   PubMed Web of Science ®Google Scholar
• Rincon M. Interleukin-6: from an inflammatory marker to a target for inflammatory diseases. Trends Immunol 2012;33(11):571–577. doi:10.1016/j.it.2012.07.003
   PubMed Web of Science ®Google Scholar
• Naik SP, PA M, BS JMadhunapantula SV, Jahromi SR, Yadav MK. Evaluation of inflammatory markers interleukin-6 (IL-6) and matrix metalloproteinase-9 (MMP-9) in asthma. J Asthma 2017;54(6):584–593. doi:10.1080/02770903.2016.1244828
   PubMed Web of Science ®Google Scholar
• Chu DK, Al-Garawi A, Llop-Guevara A, Pillai RA, Radford K, Shen P, Walker TD, Goncharova S, Calhoun WJ, Nair P, et al. Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma. Allergy Asthma Clin Immun 2015;11(1):1–6. doi:10.1186/s13223-015-0081-1
   PubMed Web of Science ®Google Scholar
• Halwani R, Al-Muhsen S, Al-Jahdali H, Hamid Q. Role of transforming growth factor–β in airway remodeling in asthma. Am J Respir Cell Mol Biol 2011;44(2):127–133. doi:10.1165/rcmb.2010-0027TR
   PubMed Web of Science ®Google Scholar
• Ito I, Fixman E, Asai K, Yoshida M, Gounni A, Martin J, Hamid Q. Platelet‐derived growth factor and transforming growth factor‐β modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells. Clin Exp Allergy 2009;39(9):1370–1380. oi:10.1111/j.1365-2222.2009.03293.x
   PubMed Web of Science ®Google Scholar
• Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, Wei D, Goldfarb KC, Santee CA, Lynch SV, et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009;139(3):485–498. doi:10.1016/j.cell.2009.09.033
   PubMed Web of Science ®Google Scholar
• Chen Z, Tato CM, Muul L, Laurence A, O'Shea JJ. Distinct regulation of interleukin‐17 in human T helper lymphocytes. Arthritis Rheum 2007;56(9):2936–2946. doi:10.1002/art.22866
   PubMed Web of Science ®Google Scholar
• Lee J, Ho W-H, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI, et al. IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. J Biol Chem 2001;276(2):1660–1664. doi:10.1074/jbc.M008289200
   PubMed Web of Science ®Google Scholar
• Starnes T, Broxmeyer HE, Robertson MJ, Hromas R. Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis. J Immunol 2002;169(2):642–646. doi:10.4049/jimmunol.169.2.642
   PubMed Web of Science ®Google Scholar
• Hellings PW, Kasran A, Liu Z, Vandekerckhove P, Wuyts A, Overbergh L, Mathieu C, Ceuppens JL. Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol 2003;28(1):42–50. doi:10.1165/rcmb.4832
   PubMed Web of Science ®Google Scholar
• Al-Ramli W, Préfontaine D, Chouiali F, Martin JG, Olivenstein R, Lemière C, Hamid Q. TH17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol 2009;123(5):1185–1187. doi:10.1016/j.jaci.2009.02.024
   PubMed Web of Science ®Google Scholar
• Molet S, Hamid Q, Davoineb F, Nutku E, Tahaa R, Pagé N, Olivenstein R, Elias J, Chakir J. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001;108(3):430–438. doi:10.1067/mai.2001.117929
   PubMed Web of Science ®Google Scholar
• Barczyk A, Pierzchala W, Sozanska E. Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine. Respir Med 2003;97(6):726–733. doi:10.1053/rmed.2003.1507
   PubMed Web of Science ®Google Scholar
• Zhou L, Ivanov II, Spolski R, Min R, Shenderov K, Egawa T, Levy DE, Leonard WJ, Littman DR. IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007;8(9):967–974. doi:10.1038/ni1488
   PubMed Web of Science ®Google Scholar
• Li Y, Yee C. IL-21–mediated Foxp3 suppression leads to enhanced generation of antigen-specific CD8+ cytotoxic T lymphocytes. Blood 2008;111(1):229–235. doi:10.1182/blood-2007-05-089375
   PubMed Web of Science ®Google Scholar
• Ratajczak W, Rył A, Mizerski A, Walczakiewicz K, Sipak O, Laszczyńska M. Immunomodulatory potential of gut microbiome-derived short-chain fatty acids (SCFAs). Acta Biochim Pol 2019;66(1):1–12. doi:10.18388/abp.2018_2648
   PubMed Web of Science ®Google Scholar
• Jiang H, Wu X, Zhu H, Xie Y, Tang S, Jiang Y. FOXP3+ Treg/Th17 cell imbalance in lung tissues of mice with asthma. Int J Clin Exp Med 2015;8(3):4158.
   PubMed Web of Science ®Google Scholar
• Fan Z, Ross RP, Stanton C, Hou B, Zhao J, Zhang H, Yang B, Chen W. Lactobacillus casei CCFM1074 alleviates collagen-induced arthritis in rats via balancing Treg/Th17 and modulating the metabolites and gut microbiota. Front Immunol 2021;12:680073. doi:10.3389/fimmu.2021.680073
   PubMed Web of Science ®Google Scholar