Role of IL-22 in acute asthma mouse model

References

• Desai M, Oppenheimer J. Elucidating asthma phenotypes and endotypes: progress towards personalized medicine. Ann Allergy Asthma Immunol. 2016;116(5):394–401. doi:10.1016/j.anai.2015.12.024.
   PubMed Web of Science ®Google Scholar
• Sur S, Crotty TB, Kephart GM, Hyma BA, Colby TV, Reed CE, Hunt LW, Gleich GJ. Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am Rev Respir Dis. 1993;148(3):713–719. doi:10.1164/ajrccm/148.3.713.
   PubMed Web of Science ®Google Scholar
• Berry MA, Hargadon B, Shelley M, Parker D, Shaw DE, Green RH, Bradding P, Brightling CE, Wardlaw AJ, Pavord ID, et al. Evidence of a role of tumor necrosis factor alpha in refractory asthma. N Engl J Med. 2006;354(7):697–708. doi:10.1056/NEJMoa050580.
   PubMed Web of Science ®Google Scholar
• Michel O, Dinh PH, Doyen V, Corazza F. Anti-TNF inhibits the airways neutrophilic inflammation induced by inhaled endotoxin in human. BMC Pharmacol Toxicol. 2014;15:60. doi:10.1186/2050-6511-15-60.
   PubMed Web of Science ®Google Scholar
• Kang JY, Jo MR, Kang HH, Kim SK, Kim MS, Kim YH, Kim SC, Kwon SS, Lee SY, Kim JW, et al. Long-term azithromycin ameliorates not only airway inflammation but also remodeling in a murine model of chronic asthma. Pulm Pharmacol Ther. 2016;36:37–45. doi:10.1016/j.pupt.2015.12.002.
   PubMed Web of Science ®Google Scholar
• Annunziato F, Romagnani C, Romagnani S. The 3 major types of innate and adaptive cell-mediated effector immunity. J Allergy Clin Immunol. 2015;135(3):626–635. doi:10.1016/j.jaci.2014.11.001.
   PubMed Web of Science ®Google Scholar
• McKinley L, Alcorn JF, Peterson A, Dupont RB, Kapadia S, Logar A, Henry A, Irvin CG, Piganelli JD, Ray A, et al. TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J Immunol. 2008;181(6):4089–4097. doi:10.4049/jimmunol.181.6.4089.
   PubMed Web of Science ®Google Scholar
• Plank MW, Kaiko GE, Maltby S, Weaver J, Tay HL, Shen W, Wilson MS, Durum SK, Foster PS. Th22 cells form a distinct Th lineage from Th17 Cells in vitro with unique transcriptional properties and Tbet-dependent Th1 plasticity. J Immunol. 2017;198(5):2182–2190. doi:10.4049/jimmunol.1601480.
   PubMed Web of Science ®Google Scholar
• Jin M, Yoon J. From bench to clinic: the potential of therapeutic targeting of the IL-22 signaling pathway in atopic dermatitis. Immune Netw. 2018;18(6):e42. doi:10.4110/in.2018.18.e42.
   PubMed Web of Science ®Google Scholar
• Nograles KE, Zaba LC, Shemer A, Fuentes-Duculan J, Cardinale I, Kikuchi T, Ramon M, Bergman R, Krueger JG, Guttman-Yassky E, et al. IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells. J Allergy Clin Immunol. 2009;123(6):1244–1252.e2. doi:10.1016/j.jaci.2009.03.041.
   PubMed Web of Science ®Google Scholar
• Eyerich S, Eyerich K, Pennino D, Carbone T, Nasorri F, Pallotta S, et al. Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest. 2009;119(12):3573–3585.
   PubMed Web of Science ®Google Scholar
• Akdis M, Palomares O, van de Veen W, van Splunter M, Akdis CA. TH17 and TH22 cells: a confusion of antimicrobial response with tissue inflammation versus protection. J Allergy Clin Immunol. 2012;129(6):1438–1449. doi:10.1016/j.jaci.2012.05.003.
   PubMed Web of Science ®Google Scholar
• Brunner PM, Pavel AB, Khattri S, Leonard A, Malik K, Rose S, Jim On S, Vekaria AS, Traidl-Hoffmann C, Singer GK, et al. Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab. J Allergy Clin Immunol. 2019;143(1):142–154. doi:10.1016/j.jaci.2018.07.028.
   PubMed Web of Science ®Google Scholar
• Guttman-Yassky E, Brunner PM, Neumann AU, Khattri S, Pavel AB, Malik K, Singer GK, Baum D, Gilleaudeau P, Sullivan-Whalen M, et al. Efficacy and safety of fezakinumab (an IL-22 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by conventional treatments: a randomized, double-blind, phase 2a trial. J Am Acad Dermatol. 2018;78(5):872–881.e6. doi:10.1016/j.jaad.2018.01.016.
   PubMed Web of Science ®Google Scholar
• Sweeney CM, Tobin AM, Kirby B. Innate immunity in the pathogenesis of psoriasis. Arch Dermatol Res. 2011;303(10):691–705. doi:10.1007/s00403-011-1169-1.
   PubMed Web of Science ®Google Scholar
• Ikeuchi H, Kuroiwa T, Hiramatsu N, Kaneko Y, Hiromura K, Ueki K, Nojima Y. Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine. Arthritis Rheum. 2005;52(4):1037–1046. doi:10.1002/art.20965.
   PubMed Web of Science ®Google Scholar
• Ito T, Hirose K, Nakajima H. Bidirectional roles of IL-22 in the pathogenesis of allergic airway inflammation. Allergol Int. 2019;68(1):4–8. doi:10.1016/j.alit.2018.10.002.
   PubMed Web of Science ®Google Scholar
• Hirose K, Ito T, Nakajima H. Roles of IL-22 in allergic airway inflammation in mice and humans. Int Immunol. 2018;30(9):413–418. doi:10.1093/intimm/dxy010.
   PubMed Web of Science ®Google Scholar
• Wang J, Gao S, Zhang J, Li C, Li H, Lin J. Interleukin-22 attenuates allergic airway inflammation in ovalbumin-induced asthma mouse model. BMC Pulm Med. 2021;21(1):385. doi:10.1186/s12890-021-01698-x.
   PubMed Web of Science ®Google Scholar
• Fang P, Zhou L, Zhou Y, Kolls JK, Zheng T, Zhu Z. Immune modulatory effects of IL-22 on allergen-induced pulmonary inflammation. PLoS One. 2014;9(9):e107454. doi:10.1371/journal.pone.0107454.
   PubMed Web of Science ®Google Scholar
• Besnard A-G, Sabat R, Dumoutier L, Renauld J-C, Willart M, Lambrecht B, Teixeira MM, Charron S, Fick L, Erard F, et al. Dual role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. Am J Respir Crit Care Med. 2011;183(9):1153–1163. doi:10.1164/rccm.201008-1383OC.
   PubMed Web of Science ®Google Scholar
• Lilly LM, Gessner MA, Dunaway CW, Metz AE, Schwiebert L, Weaver CT, Brown GD, Steele C. The β-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22. J Immunol. 2012;189(7):3653–3660. doi:10.4049/jimmunol.1201797.
   PubMed Web of Science ®Google Scholar
• Carr TF, Zeki AA, Kraft M. Eosinophilic and noneosinophilic asthma. Am J Respir Crit Care Med. 2018;197(1):22–37. doi:10.1164/rccm.201611-2232PP.
   PubMed Web of Science ®Google Scholar
• Kim Y-K, Oh S-Y, Jeon SG, Park H-W, Lee S-Y, Chun E-Y, Bang B, Lee H-S, Oh M-H, Kim Y-S, et al. Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma. J Immunol. 2007;178(8):5375–5382. doi:10.4049/jimmunol.178.8.5375.
   PubMed Web of Science ®Google Scholar
• Yu QL, Chen Z. Establishment of different experimental asthma models in mice. Exp Ther Med. 2018;15(3):2492–2498. doi:10.3892/etm.2018.5721.
   PubMed Web of Science ®Google Scholar
• Padrid P, Snook S, Finucane T, Shiue P, Cozzi P, Solway J, Leff AR. Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats. Am J Respir Crit Care Med. 1995;151(1):184–193. doi:10.1164/ajrccm.151.1.7812551.
   PubMed Web of Science ®Google Scholar
• Myou S, Leff AR, Myo S, Boetticher E, Tong J, Meliton AY, Liu J, Munoz NM, Zhu X. Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT. J Exp Med. 2003;198(10):1573–1582. doi:10.1084/jem.20030298.
   PubMed Web of Science ®Google Scholar
• Ravi A, Chowdhury S, Dijkhuis A, Bonta PI, Sterk PJ, Lutter R. Neutrophilic inflammation in asthma and defective epithelial translational control. Eur Respir J. 2019;54(2):1900547. doi:10.1183/13993003.00547-2019.
   PubMed Web of Science ®Google Scholar
• Liu C, Zhang X, Xiang Y, Qu X, Liu H, Liu C, Tan M, Jiang J, Qin X. Role of epithelial chemokines in the pathogenesis of airway inflammation in asthma (Review). Mol Med Rep. 2018;17(5):6935–6941.
   PubMed Web of Science ®Google Scholar
• Busse WW, Holgate S, Kerwin E, Chon Y, Feng J, Lin J, Lin S-L. Randomized, double-blind, placebo-controlled study of brodalumab, a human anti-IL-17 receptor monoclonal antibody, in moderate to severe asthma. Am J Respir Crit Care Med. 2013;188(11):1294–1302. doi:10.1164/rccm.201212-2318OC.
   PubMed Web of Science ®Google Scholar
• Dudakov JA, Hanash AM, van den Brink MR. Interleukin-22: immunobiology and pathology. Annu Rev Immunol. 2015;33:747–785. doi:10.1146/annurev-immunol-032414-112123.
   PubMed Web of Science ®Google Scholar
• Sabat R, Ouyang W, Wolk K. Therapeutic opportunities of the IL-22-IL-22R1 system. Nat Rev Drug Discov. 2014;13(1):21–38. doi:10.1038/nrd4176.
   PubMed Web of Science ®Google Scholar
• Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S. Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity. J Immunol. 2001;166(12):7096–7103. doi:10.4049/jimmunol.166.12.7096.
   PubMed Web of Science ®Google Scholar
• Broquet A, Jacqueline C, Davieau M, Besbes A, Roquilly A, Martin J, Caillon J, Dumoutier L, Renauld J-C, Heslan M, et al. Interleukin-22 level is negatively correlated with neutrophil recruitment in the lungs in a Pseudomonas aeruginosa pneumonia model. Sci Rep. 2017;7(1):11010. doi:10.1038/s41598-017-11518-0.
   PubMed Web of Science ®Google Scholar
• Johnson JR, Nishioka M, Chakir J, Risse P-A, Almaghlouth I, Bazarbashi AN, Plante S, Martin JG, Eidelman D, Hamid Q, et al. IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells. Respir Res. 2013;14(1):118. doi:10.1186/1465-9921-14-118.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Yang J, Gao YD, Guo W. Th17 immunity in patients with allergic asthma. Int Arch Allergy Immunol. 2010;151(4):297–307. doi:10.1159/000250438.
   PubMed Web of Science ®Google Scholar
• Farfariello V, Amantini C, Nabissi M, Morelli MB, Aperio C, Caprodossi S, Carlucci A, Bianchi AM, Santoni G. IL-22 mRNA in peripheral blood mononuclear cells from allergic rhinitic and asthmatic pediatric patients. Pediatr Allergy Immunol. 2011;22(4):419–423. doi:10.1111/j.1399-3038.2010.01116.x.
   PubMed Web of Science ®Google Scholar
• Leyva-Castillo JM, Yoon J, Geha RS. IL-22 promotes allergic airway inflammation in epicutaneously sensitized mice. J Allergy Clin Immunol. 2019;143(2):619–630.e7. doi:10.1016/j.jaci.2018.05.032.
   PubMed Web of Science ®Google Scholar
• Ito T, Hirose K, Saku A, Kono K, Takatori H, Tamachi T, Goto Y, Renauld J-C, Kiyono H, Nakajima H, et al. IL-22 induces Reg3γ and inhibits allergic inflammation in house dust mite-induced asthma models. J Exp Med. 2017;214(10):3037–3050. doi:10.1084/jem.20162108.
   PubMed Web of Science ®Google Scholar
• Takahashi K, Hirose K, Kawashima S, Niwa Y, Wakashin H, Iwata A, Tokoyoda K, Renauld J-C, Iwamoto I, Nakayama T, et al. IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation. J Allergy Clin Immunol. 2011;128(5):1067–1076. doi:10.1016/j.jaci.2011.06.018.
   PubMed Web of Science ®Google Scholar
• Nakagome K, Imamura M, Kawahata K, Harada H, Okunishi K, Matsumoto T, Sasaki O, Tanaka R, Kano MR, Chang H, et al. High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism. J Immunol. 2011;187(10):5077–5089. doi:10.4049/jimmunol.1001560.
   PubMed Web of Science ®Google Scholar
• Castro M, Zangrilli J, Wechsler ME, Bateman ED, Brusselle GG, Bardin P, Murphy K, Maspero JF, O'Brien C, Korn S, et al. Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials. Lancet Respir Med. 2015;3(5):355–366. doi:10.1016/S2213-2600(15)00042-9.
   PubMed Web of Science ®Google Scholar
• Ortega HG, Liu MC, Pavord ID, Brusselle GG, FitzGerald JM, Chetta A, Humbert M, Katz LE, Keene ON, Yancey SW, et al. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med. 2014;371(13):1198–1207. doi:10.1056/NEJMoa1403290.
   PubMed Web of Science ®Google Scholar
• Hanania NA, Noonan M, Corren J, Korenblat P, Zheng Y, Fischer SK, Cheu M, Putnam WS, Murray E, Scheerens H, et al. Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies. Thorax. 2015;70(8):748–756. doi:10.1136/thoraxjnl-2014-206719.
   PubMed Web of Science ®Google Scholar
• Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, Geha RS. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest. 1998;101(8):1614–1622. doi:10.1172/JCI1647.
   PubMed Web of Science ®Google Scholar
• Wan R, Jiang J, Hu C, Chen X, Chen C, Zhao B, Hu X, Zheng Z, Li Y. Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/NF-κB pathway and secrete chemokines. Aging (Albany NY). 2020;12(17):16820–16836. doi:10.18632/aging.103479.
   PubMedGoogle Scholar
• Manni ML, Trudeau JB, Scheller EV, Mandalapu S, Elloso MM, Kolls JK, Wenzel SE, Alcorn JF. The complex relationship between inflammation and lung function in severe asthma. Mucosal Immunol. 2014;7(5):1186–1198. doi:10.1038/mi.2014.8.
   PubMed Web of Science ®Google Scholar
• Pichavant M, Charbonnier A-S, Taront S, Brichet A, Wallaert B, Pestel J, Tonnel A-B, Gosset P. Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment. J Allergy Clin Immunol. 2005;115(4):771–778. doi:10.1016/j.jaci.2004.11.043.
   PubMed Web of Science ®Google Scholar
• Hastie AT, Moore WC, Meyers DA, Vestal PL, Li H, Peters SP, Bleecker ER. Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes. J Allergy Clin Immunol. 2010;125(5):1028–1036.e13. doi:10.1016/j.jaci.2010.02.008.
   PubMed Web of Science ®Google Scholar
• Nozato K, Fujita J, Kawaguchi M, Ohara G, Morishima Y, Ishii Y, Huang S-K, Kokubu F, Satoh H, Hizawa N, et al. IL-17F induces CCL20 in bronchial epithelial cells. J Allergy (Cairo). 2011;2011:587204. doi:10.1155/2011/587204.
   PubMedGoogle Scholar
• He X, Li H, Chen Y, Chen A, Shan K, Chen J, Zhao H, Zhang X, Cai T. The effects of IL-22 on the inflammatory mediator production, proliferation, and barrier function of HUVECs. Inflammation. 2016;39(3):1099–1107. doi:10.1007/s10753-016-0341-3.
   PubMed Web of Science ®Google Scholar