A cross-sectional study to evaluate utility measure and health-related quality of life (HRQoL) among patients with severe uncontrolled asthma in Spain

References

• Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SAA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, et al. Severe asthma: lessons learned from the national heart, lung, and blood institute severe asthma research program. Am J Respir Crit Care Med. 2012;185(4):356–362. doi:10.1164/rccm.201107-1317PP.
   PubMed Web of Science ®Google Scholar
• GEMA 5.2 Spanish guideline for the management of asthma; 2022. Available from: www.gemasma.com
   Google Scholar
• Global Initiative for Asthma. Global strategy for asthma management and prevention; 2022. Available from: www.ginasthma.org
   Google Scholar
• Athanazio R, Carvalho-Pinto R, Fernandes FL, Rached S, Rabe K, Cukier A, Stelmach R. Can severe asthmatic patients achieve asthma control? A systematic approach in patients with difficult to control asthma followed in a specialized clinic. BMC Pulm Med. 2016;16(1):153. doi:10.1186/s12890-016-0314-1.
   PubMed Web of Science ®Google Scholar
• Wang E, Wechsler ME, Tran TN, Heaney LG, Jones RC, Menzies-Gow AN, Busby J, Jackson DJ, Pfeffer PE, Rhee CK, et al. Characterization of severe asthma worldwide: data from the international severe asthma registry. Chest. 2020;157(4):790–804. doi:10.1016/j.chest.2019.10.053.
   PubMed Web of Science ®Google Scholar
• McDonald VM, Hiles SA, Jones KA, Clark VL, Yorke J. Health-related quality of life burden in severe asthma. Med J Aust. 2018;209(S2):S28–S33. doi:10.5694/mja18.00207.
   PubMed Web of Science ®Google Scholar
• NICE U: guide to the methods of technology appraisal. London: National Institute for Health and Clinical Excellence (NICE); 2013.
   Google Scholar
• Szentes BL, Schultz K, Nowak D, Schuler M, Schwarzkopf L. How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire? BMC Pulm Med. 2020;20(1):168. doi:10.1186/s12890-020-01205-8.
   PubMed Web of Science ®Google Scholar
• Quirce S, Plaza V, Picado C, Vennera M, Casafont J. Prevalence of uncontrolled severe persistent asthma in pneumology and allergy hospital units in Spain. J Investig Allergol Clin Immunol. 2011;21(6):466–471.
   PubMed Web of Science ®Google Scholar
• Gonzalez-Barcala F-J, de la Fuente-Cid R, Tafalla M, Nuevo J, Caamaño-Isorna F. Factors associated with health-related quality of life in adults with asthma. A cross-sectional study. Multidiscip Respir Med. 2012;7(1):32. doi:10.1186/2049-6958-7-32.
   PubMed Web of Science ®Google Scholar
• Sanjuás C, Alonso J, Prieto L, Ferrer M, Broquetas JM, Antó JM. Ant: health-related quality of life in asthma: a comparison between the St George’s respiratory questionnaire and the asthma quality of life questionnaire. Qual Life Res. 2002;11(8):729–738. doi:10.1023/a:1020897816228.
   PubMed Web of Science ®Google Scholar
• Sanjuàs C, Alonso J, Sanchís J, Casan P, Broquetas JM, Ferrie PJ, Juniper EF, Antó JM. Ant: Cuestionario de calidad de vida en pacientes con asma: la versión española del asthma quality of life questionnaire. Arch Bronconeumol. 1995;31(5):219–226. doi:10.1016/s0300-2896(15)30927-3.
   PubMedGoogle Scholar
• Knies S, Evers SM, Candel MJ, Severens JL, Ament AJ. Utilities of the EQ-5D: transferable or not? Pharmacoeconomics. 2009;27(9):767–779. doi:10.2165/11314120-000000000-00000.
   PubMed Web of Science ®Google Scholar
• Virgili G, Koleva D, Garattini L, Banzi R, Gensini GF. Utilities and QALYs in health economic evaluations: glossary and introduction. Intern Emerg Med. 2010;5(4):349–352. doi:10.1007/s11739-010-0420-7.
   PubMed Web of Science ®Google Scholar
• Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(5):439–458.
   PubMed Web of Science ®Google Scholar
• Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald JM, Gibson P, Ohta K, O’Byrne P, Pedersen SE, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J. 2008;31(1):143–178. doi:10.1183/09031936.00138707.
   PubMed Web of Science ®Google Scholar
• Hernandez G, Dima AL, Pont À, Garin O, Martí-Pastor M, Alonso J, Van Ganse E, Laforest L, de Bruin M, Mayoral K, et al. Impact of asthma on women and men: comparison with the general population using the EQ-5D-5L questionnaire. PLOS One. 2018;13(8):e0202624. doi:10.1371/journal.pone.0202624.
   PubMed Web of Science ®Google Scholar
• Williams SA, Wagner S, Kannan H, Bolge SC. The association between asthma control and health care utilization, work productivity loss and health-related quality of life. J Occup Environ Med. 2009;51(7):780–785. doi:10.1097/JOM.0b013e3181abb019.
   PubMed Web of Science ®Google Scholar
• Juniper EF, Guyatt GH, Epstein RS, Ferrie PJ, Jaeschke R, Hiller TK. Evaluation of impairment of health related quality of life in asthma: development of a questionnaire for use in clinical trials. Thorax. 1992;47(2):76–83. doi:10.1136/thx.47.2.76.
   PubMed Web of Science ®Google Scholar
• Hernandez G, Garin O, Dima AL, Pont A, Martí Pastor M, Alonso J, Van Ganse E, Laforest L, de Bruin M, Mayoral K, et al. EuroQol (EQ-5D-5L) validity in assessing the quality of life in adults with asthma: cross-sectional study. J Med Internet Res. 2019;21(1):e10178. doi:10.2196/10178.
   PubMed Web of Science ®Google Scholar
• Szentes BL, Schultz K, Nowak D, Schuler M, Schwarzkopf L, Yang Y, Brazier JE, Tsuchiya A, Young TA, Hernandez G, et al. Estimating a preference-based index for a 5-dimensional health state classification for asthma derived from the asthma quality of life questionnaire. Med Decis Making. 2011;31(2):281–291. doi:10.1177/0272989X10379646.
   PubMed Web of Science ®Google Scholar
• Akoglu H. User’s guide to correlation coefficients. Turk J Emerg Med. 2018;18(3):91–93. doi:10.1016/j.tjem.2018.08.001.
   PubMed Web of Science ®Google Scholar
• Adams R, Wakefield M, Wilson D, Parsons J, Campbell D, Smith B, Ruffin R. Quality of life in asthma: a comparison of community and hospital asthma patients. J Asthma. 2001. 38(3):205–214. doi:10.1081/jas-100000107.
   PubMed Web of Science ®Google Scholar
• Adams RJ, Fuhlbrigge A, Guilbert T, Lozano P, Martinez F. Inadequate use of asthma medication in the United States: results of the asthma in America national population survey. J Allergy Clin Immunol. 2002;110(1):58–64. doi:10.1067/mai.2002.125489.
   PubMed Web of Science ®Google Scholar
• Fernandes A, Oliveira MA. Avaliação o da qualidade de vida na asma. J Pneumol. 1997;23(3):148–152.
   Google Scholar
• Juniper EF. Assessing asthma quality of life: its role in clinical practice. Breathe. 2005;1(3):192–204. doi:10.1183/18106838.0103.192.
   Google Scholar
• Pereira EDB, Cavalcante A, Pereira ENS, Lucas P, Holanda MA. Asthma control and quality of life in patients with moderate or severe asthma. J Bras Pneumol. 2011;37(6):705–711. doi:10.1590/s1806-37132011000600002.
   PubMed Web of Science ®Google Scholar
• Lee LK, Ramakrishnan K, Safioti G, Ariely R, Schatz M. Asthma control is associated with economic outcomes, work productivity and health-related quality of life in patients with asthma. BMJ Open Respiratory Res. 2020;7(1):e000534. doi:10.1136/bmjresp-2019-000534.
   PubMed Web of Science ®Google Scholar
• Brazier J, Roberts J, Tsuchiya A, Busschbach J. A comparison of the EQ-5D and SF-6D across seven patient groups. Health Econ. 2004;13(9):873–884. doi:10.1002/hec.866.
   PubMed Web of Science ®Google Scholar
• Kontodimopoulos N, Stamatopoulou E, Brinia A, Talias MA, Ferreira LN. Are condition-specific utilities more valid than generic preference-based ones in asthma? Evidence from a study comparing EQ-5D-3L and SF-6D with AQL-5D. Expert Rev Pharmacoecon Outcomes Res. 2018;18(6):667–675. doi:10.1080/14737167.2018.1505506.
   PubMed Web of Science ®Google Scholar
• Freemantle N. Cost-effectiveness in health and medicine. BMJ. 1997;315(7109):689–689. doi:10.1136/bmj.315.7109.689a.
   Google Scholar
• Postma DS. Gender differences in asthma development and progression. Gend Med. 2007;4(Suppl. 2):S133–S146. doi:10.1016/s1550-8579(07)80054-4.
   PubMedGoogle Scholar
• Boulet L-P. Influence of comorbid conditions on asthma. Eur Respir J. 2009;33(4):897–906. doi:10.1183/09031936.00121308.
   PubMed Web of Science ®Google Scholar
• Pérez De Llano LA, González FC, Añón OC, Perea MP, Caruncho MV, Villar AB. Relationship between the presence of comorbidity and asthma control [Relación entre presencia de comorbilidad y control del asma]. Arch Bronconeumol. 2010;46(10):508–513. doi:10.1016/j.arbres.2010.05.008.
   PubMedGoogle Scholar
• Kumarathas I, Harsløf T, Andersen CU, Langdahl B, Hilberg O, Bjermer L, Løkke A. The risk of osteoporosis in patients with asthma. Eur Clin Respir J. 2020;7(1):1763612. doi:10.1080/20018525.2020.1763612.
   PubMed Web of Science ®Google Scholar
• Kearney DM, Lockey RF. Osteoporosis and asthma. Ann Allergy Asthma Immunol. 2006;96(6):769–776. doi:10.1016/S1081-1206(10)61338-5.
   PubMed Web of Science ®Google Scholar
• Galli E, Gianni S, Auricchio G, Brunetti E, Mancino G, Rossi P. Atopic dermatitis and asthma. Allergy Asthma Proc. 2007;28(5):540–543. doi:10.2500/aap2007.28.3048.
   PubMed Web of Science ®Google Scholar
• Castillo JR, Peters SP, Busse WW. Asthma exacerbations: pathogenesis, prevention, and treatment. J Allergy Clin Immunol Pract. 2017;5(4):918–927. doi:10.1016/j.jaip.2017.05.001.
   PubMed Web of Science ®Google Scholar
• Busse W, Chupp G, Nagase H, Albers FC, Doyle S, Shen Q, Bratton DJ, Gunsoy NB. Anti-IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: indirect treatment comparison. J Allergy Clin Immunol. 2019;143(1):190–200.e120. doi:10.1016/j.jaci.2018.08.031.
   PubMed Web of Science ®Google Scholar
• Coverstone AM, Seibold MA, Peters MC. Diagnosis and management of T2-high asthma. J Allergy Clin Immunol Pract. 2020;8(2):442–450. doi:10.1016/j.jaip.2019.11.020.
   PubMed Web of Science ®Google Scholar
• Economic impact of severe asthma in Spain: multicentre observational longitudinal study. J Asthma. 2019;56(8):861–871.
   PubMed Web of Science ®Google Scholar
• Chastek B, Korrer S, Nagar SP, Albers F, Yancey S, Ortega H, Forshag M, Dalal AA. Economic burden of illness among patients with severe asthma in a managed care setting. J Manag Care Spec Pharm. 2016;22(7):848–861. doi:10.18553/jmcp.2016.22.7.848.
   PubMedGoogle Scholar
• Lee YH, Yoon SJ, Kim EJ, Kim YA, Seo HY, Oh IH. Economic burden of asthma in Korea. Allergy Asthma Proc. 2011;32(6):35–40. doi:10.2500/aap.2011.32.3479.
   PubMed Web of Science ®Google Scholar
• Ehteshami-Afshar S, FitzGerald JM, Carlsten C, Tavakoli H, Rousseau R, Tan WC, Rolf JD, Sadatsafavi M. The impact of comorbidities on productivity loss in asthma patients. Respir Res. 2016;17(1):106. doi:10.1186/s12931-016-0421-9.
   PubMed Web of Science ®Google Scholar
• Inoue H, Kozawa M, Milligan KL, Funakubo M, Igarashi A, Loefroth E. A retrospective cohort study evaluating healthcare resource utilization in patients with asthma in Japan. NPJ Prim Care Respir Med. 2019;29(1):13. doi:10.1038/s41533-019-0128-8.
   PubMedGoogle Scholar
• Jacob C, Bechtel B, Engel S, Kardos P, Linder R, Braun S, Greiner W. Healthcare costs and resource utilization of asthma in Germany: a claims data analysis. Eur J Health Econ. 2016;17(2):195–201. doi:10.1007/s10198-015-0671-3.
   PubMed Web of Science ®Google Scholar
• Nunes C, Pereira AM, Morais-Almeida M. Asthma costs and social impact. Asthma Res Pract. 2017;3(1):1–11. doi:10.1186/s40733-016-0029-3.
   PubMedGoogle Scholar
• Suruki RY, Daugherty JB, Boudiaf N, Albers FC. The frequency of asthma exacerbations and healthcare utilization in patients with asthma from the UK and USA. BMC Pulm Med. 2017;17(1):74. doi:10.1186/s12890-017-0409-3.
   PubMed Web of Science ®Google Scholar
• Matsunaga K, Hirano T, Oka A, Tanaka A, Kanai K, Kikuchi T, Hayata A, Akamatsu H, Akamatsu K, Koh Y, et al. Progression of irreversible airflow limitation in asthma: correlation with severe exacerbations. J Allergy Clin Immunol Pract. 2015;3(5):759–764.e1. doi:10.1016/j.jaip.2015.05.005.
   PubMed Web of Science ®Google Scholar
• Hartmann-Boyce J, Gunnell J, Drake J, Otunla A, Suklan J, Schofield E, Kinton J, Inada-Kim M, Hobbs FDR, Dennison P. Asthma and COVID-19: review of evidence on risks and management considerations. BMJ Evidence-Based Med. 2021;26(4):195. doi:10.1136/bmjebm-2020-111506.
   Google Scholar