Multivariate analysis and data mining help predict asthma exacerbations

References

• Ye Q, Liao A, D’Urzo A. FEV1 reversibility for asthma diagnosis: a critical evaluation. Expert Rev Respir Med. 2018;12(4):265–267. doi:10.1080/17476348.2018.1439741.
   PubMed Web of Science ®Google Scholar
• Louis R, Satia I, Ojanguren I, Schleich F, Bonini M, Tonia T, Rigau D, Ten Brinke A, Buhl R, Loukides S, et al. European Respiratory Society guidelines for the diagnosis of asthma in adults. Eur Respir J. 2022;60(3):2101585. doi:10.1183/13993003.01585-2021.
   Web of Science ®Google Scholar
• https://ginasthma.org/wp-content/uploads/2022/07/GINA-Main-Report-2022-FINAL-22-07-01-WMS.pdf. (accessed on 23 May 2023).
   Google Scholar
• Boulet LP, Reddel HK, Bateman E, Pedersen S, FitzGerald JM, O’Byrne PM. The Global Initiative for Asthma (GINA): 25 years later. Eur Respir J. 2019;54(2):1900598. 1pii. doi:10.1183/13993003.00598-2019.
   PubMed Web of Science ®Google Scholar
• Haughney J, Price D, Kaplan A, Chrystyn H, Horne R, May N, Moffat M, Versnel J, Shanahan ER, Hillyer EV, et al. Achieving asthma control in practice: understanding the reasons for poor control. Respir Med. 2008;102(12):1681–1693. doi:10.1016/j.rmed.2008.08.003.
   PubMed Web of Science ®Google Scholar
• Levy ML, Bacharier LB, Bateman E, Boulet L-P, Brightling C, Buhl R, Brusselle G, Cruz AA, Drazen JM, Duijts L, et al. Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update. NPJ Prim Care Respir Med. 2023;33(1):7. doi:10.1038/s41533-023-00330-1.
   PubMed Web of Science ®Google Scholar
• Lundback B, Dahl R. Assessment of asthma control and its impact on optimal treatment strategy. Allergy. 2007;62(6):611–619. doi:10.1111/j.1398-9995.2007.01399.x.
   PubMed Web of Science ®Google Scholar
• Combescure C, Chanez P, Saint-Pierre P, Daurès JP, Proudhon H, Godard P, Association pour la Recherche en Intelligence Artificielle group. Assessment of variations in control of asthma over time. Eur Respir J. 2003;22(2):298–304. doi:10.1183/09031936.03.00081102.
   PubMed Web of Science ®Google Scholar
• Boulet LP, Reddel HK, Brightling C, Brusselle G. GINA fosters World Asthma Day 2020 to prevent asthma deaths. Am J Physiol Lung Cell Mol Physiol. 2020;318(5):L998–L1000. doi:10.1152/ajplung.00075.2020.
   PubMed Web of Science ®Google Scholar
• Schatz M, Sorkness CA, Li JT, Marcus P, Murray J, Nathan RA, Kosinski M, Pendergraft T, Jhingran P. Asthma control test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. J Allergy Clin Immunol. 2006;117(3):549–556. doi:10.1016/j.jaci.2006.01.011.
   PubMed Web of Science ®Google Scholar
• van Dijk BCP, Svedsater H, Heddini A, Nelsen L, Balradj JS, Alleman C. Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review. BMC Pulm Med. 2020;20(1):79. doi:10.1186/s12890-020-1090-5.
   PubMed Web of Science ®Google Scholar
• Maestrelli P, Henneberger PK, Tarlo S, Mason P, Boschetto P. Causes and phenotypes of work-related asthma. Int J Environ Res Public Health. 2020;17(13):4713. doi:10.3390/ijerph17134713.
   PubMed Web of Science ®Google Scholar
• Baur X, Sigsgaard T, Aasen TB, Burge PS, Heederik D, Henneberger P, Maestrelli P, Rooyackers J, Schlünssen V, Vandenplas O, on behalf of the ERS Task Force on the Management of Work-related Asthma, et al. Guidelines for the management of work-related asthma. Eur Respir J. 2012;39(3):529–545. doi:10.1183/09031936.00096111.
   PubMed Web of Science ®Google Scholar
• Cormier M, Lemière C. Occupational asthma. Int J Tuberc Lung Dis. 2020;24(1):8–21. doi:10.5588/ijtld.19.0301.
   PubMed Web of Science ®Google Scholar
• Kim JL, Henneberger PK, Lohman S, Olin AC, Dahlman-Höglund A, Andersson E, Torén K, Holm M. Impact of occupational exposures on exacerbation of asthma: a population-based asthma cohort study. BMC Pulm Med. 2016;16(1):148. doi:10.1186/s12890-016-0306-1.
   PubMed Web of Science ®Google Scholar
• Quirce S, Domínguez-Ortega J, Luna JA. Novel approaches in occupational asthma diagnosis and management. Curr Opin Pulm Med. 2021;27(1):9–14. doi:10.1097/MCP.0000000000000737.
   PubMed Web of Science ®Google Scholar
• Olivieri M, Murgia N, Spiteri G, Biscardo CA, Marchetti P, Folletti I, Verlato G. Exposure to additives or multigrain flour is associated with high risk of work-related allergic symptoms among bakers. Occup Environ Med. 2021;78(2):112–116. doi:10.1136/oemed-2019-106052.
   PubMed Web of Science ®Google Scholar
• Gehring U, Wijga AH, Brauer M, Fischer P, de Jongste JC, Kerkhof M, Oldenwening M, Smit HA, Brunekreef B. Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life. Am J Respir Crit Care Med. 2010;181(6):596–603. doi:10.1164/rccm.200906-0858OC.
   PubMed Web of Science ®Google Scholar
• Demange V, Zmirou-Navier D, Bohadana A, Wild P. Do airway inflammation and airway responsiveness markers at the start of apprenticeship predict their evolution during initial training? A longitudinal study among apprentice bakers, pastry makers and hairdressers. BMC Pulm Med. 2018;18(1):113. doi:10.1186/s12890-018-0674-9.
   PubMedGoogle Scholar
• Vested A, Kolstad HA, Basinas I, Burdorf A, Elholm G, Heederik D, Jacobsen GH, Kromhout H, Omland Ø, Schaumburg I, et al. Dust exposure and the impact on hospital readmission of farming and wood industry workers for asthma and chronic obstructive pulmonary disease (COPD). Scand J Work Environ Health. 2021;47(2):163–168. doi:10.5271/sjweh.3926.
   PubMed Web of Science ®Google Scholar
• Clausen PA, Frederiksen M, Sejbæk CS, Sørli JB, Hougaard KS, Frydendall KB, Carøe TK, Flachs EM, Meyer HW, Schlünssen V, et al. Chemicals inhaled from spray cleaning and disinfection products and their respiratory effects. A comprehensive review. Int J Hyg Environ Health. 2020;229:113592. doi:10.1016/j.ijheh.2020.113592.
   PubMed Web of Science ®Google Scholar
• Tiotiu A, Novakova P, Baiardini I, Bikov A, Chong-Neto HJ, Correia-de-Sousa J, Emelyanov A, Heffler E, Fogelbach GG, Kowal K, et al. Manifesto on United Airways Diseases (UAD): an Interasma (Global Asthma Association - GAA) document. J Asthma. 2022;59(4):639–654. doi:10.1080/02770903.2021.1879130.
   PubMed Web of Science ®Google Scholar
• Sadeghniiat-Haghighi K, Aminian O, Najafi A, Salehpour S, Eslaminejad A, Derakhshan Deilami G, Nourijelyani K, Tarlo SM. Work-related exacerbation of asthma among adults treated by pulmonary specialists. Arch Environ Occup Health. 2016;71(1):35–42. doi:10.1080/19338244.2014.941094.
   PubMed Web of Science ®Google Scholar
• Lai CK, Beasley R, Crane J, Foliaki S, Shah J, Weiland S, ISAAC Phase Three Study Group. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009;64(6):476–483. doi:10.1136/thx.2008.106609.
   PubMed Web of Science ®Google Scholar
• Graham BL, Steenbruggen I, Miller MR, Barjaktarevic IZ, Cooper BG, Hall GL, Hallstrand TS, Kaminsky DA, McCarthy K, McCormack MC, et al. Standardization of spirometry 2019 update. An official American thoracic society and European respiratory society technical statement. Am J Respir Crit Care Med. 2019;200(8):e70-88–e88. doi:10.1164/rccm.201908-1590ST.
   Web of Science ®Google Scholar
• Géron A. Hands-on machine learning with Scikit-Learn, Keras, and TensorFlow. Sebastopol, CA: O’Reilly Media, Inc.; 2022.
   Google Scholar
• Ley C, Martin RK, Pareek A, Groll A, Seil R, Tischer T. Machine learning and conventional statistics: making sense of the differences. Knee Surg Sports Traumatol Arthrosc. 2022;30(3):753–757. doi:10.1007/s00167-022-06896-6.
   PubMed Web of Science ®Google Scholar
• Mihaicuta S, Udrescu L, Tiotiu A, Nadasan V, Frent SM. Occupational exposure as a predictor of asthma exacerbation – a multicenter multivariate logistical analysis. European Respiratory Journal. 2021;58: PA1907. doi:10.1183/13993003.congress-2021.PA1907.
   Web of Science ®Google Scholar
• Tiotiu AI, Novakova S, Labor M, Emelyanov A, Mihaicuta S, Novakova P, Nedeva D. Progress in occupational asthma. Int J Environ Res Public Health. 2020;17(12):4553. doi:10.3390/ijerph17124553.
   PubMed Web of Science ®Google Scholar
• Muñoz X, Cruz MJ, Bustamante V, Lopez-Campos JL, Barreiro E. Work-related asthma: diagnosis and prognosis of immunological occupational asthma and work-exacerbated asthma. J Investig Allergol Clin Immunol. 2014;24(6):396–405.
   PubMed Web of Science ®Google Scholar
• Jeebhay MF, Quirce S. Occupational asthma in the developing and industrialised world: a review. Int J Tuberculosis Lung Dis. 2007;11(2):122–133.
   PubMed Web of Science ®Google Scholar
• Mendy A, Gasana J, Forno E, Vieira ER, Dowdye C. Work-related respiratory symptoms and lung function among solderers in the electronics industry: a meta-analysis. Environ Health Prev Med. 2012;17(3):183–190. doi:10.1007/s12199-011-0236-8.
   PubMedGoogle Scholar
• Coureau E, Fontana L, Lamouroux C, Pélissier C, Charbotel B. Is isocyanate exposure and occupational asthma still a major occupational health concern? Systematic literature review. Int J Environ Res Public Health. 2021;18(24):13181. doi:10.3390/ijerph182413181.
   PubMed Web of Science ®Google Scholar
• Chan-Yeung M, Malo J-L. Tables of major inducers of occupational asthma. In: Bernstein IL, Chan-Yeung M, Malo J-L, Bernstein DI, eds. Asthma in the workplace, part IV. New York: Marcel Dekker, 1999. p. 683–720.
   Google Scholar
• Tiotiu A, Thaon I, Poussel M, Penven E. Occupational asthma caused by powder paint in the automotive industry. J Investig Allergol Clin Immunol. 2019;29(4):316–318. doi:10.18176/jiaci.0394.
   PubMed Web of Science ®Google Scholar
• Siracusa A, De Blay F, Folletti I, Moscato G, Olivieri M, Quirce S, Raulf‐Heimsoth M, Sastre J, Tarlo SM, Walusiak‐Skorupa J, et al. Asthma and exposure to cleaning products–a European Academy of Allergy and Clinical Immunology task force consensus statement. Allergy. 2013;68(12):1532–1545. doi:10.1111/all.12279.
   PubMed Web of Science ®Google Scholar
• Walters GI, Burge PS, Moore VC, Robertson AS. Cleaning agent occupational asthma in the West Midlands, UK: 2000–16. Occup Med (Lond). 2018;68(8):530–536. doi:10.1093/occmed/kqy113.
   PubMed Web of Science ®Google Scholar
• Minov J. Occupational chronic obstructive pulmonary disorder: prevalence and prevention. Expert Rev Respir Med. 2022;16(4):429–436. doi:10.1080/17476348.2021.2011722.
   PubMed Web of Science ®Google Scholar
• Brisman J. Baker’s asthma. Occup Environ Med. 2002;59(7):498–502; quiz 502, 426. doi:10.1136/oem.59.7.498.
   PubMed Web of Science ®Google Scholar
• Bornehag CG, Sundell J, Weschler CJ, Sigsgaard T, Lundgren B, Hasselgren M, Hägerhed-Engman L. The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case–control study. Environ Health Perspect. 2004;112(14):1393–1397. doi:10.1289/ehp.7187.
   PubMed Web of Science ®Google Scholar
• Moscato G, Pignatti P, Yacoub MR, Romano C, Spezia S, Perfetti L. Occupational asthma and occupational rhinitis in hairdressers. Chest. 2005;128(5):3590–3598. doi:10.1378/chest.128.5.3590.
   PubMed Web of Science ®Google Scholar
• Zeleke ZK, Moen BE, Bråtveit M. Lung function reduction and chronic respiratory symptoms among workers in the cement industry: a follow up study. BMC Pulm Med. 2011;11(1):50. doi:10.1186/1471-2466-11-50.
   PubMedGoogle Scholar
• Quirce S, Barranco P. Cleaning agents and asthma. J Investig Allergol Clin Immunol. 2010;20(7):542–550; quiz 2p following 550.
   PubMed Web of Science ®Google Scholar
• Frey U. Predicting asthma control and exacerbations: chronic asthma as a complex dynamic model. Curr Opin Allergy Clin Immunol. 2007;7(3):223–230. doi:10.1097/ACI.0b013e32810fd771.
   PubMed Web of Science ®Google Scholar
• Cajigal S, Wells KE, Peterson EL, Ahmedani BK, Yang JJ, Kumar R, Burchard EG, Williams LK. Predictive properties of the asthma control test and its component questions for severe asthma exacerbations. J Allergy Clin Immunol Pract. 2017;5(1):121–127.e2. doi:10.1016/j.jaip.2016.06.025.
   PubMed Web of Science ®Google Scholar
• Martínez-Moragón E, Delgado J, Mogrovejo S, Fernández-Sánchez T, Jesús JL, Ángel MOM, Patricia PM, Miguel TT, Begoña CO, Ángel FT, et al. Factors that determine the loss of control when reducing therapy by steps in the treatment of moderate-severe asthma in standard clinical practice: a multicentre Spanish study. Rev Clin Esp (Barc). 2020;220(2):86–93. doi:10.1016/j.rce.2019.05.004.
   PubMed Web of Science ®Google Scholar
• Braido F, Tiotiu A, Kowal K, Mihaicuta S, Novakova P, Oguzulgen IK. Phenotypes/endotypes-driven treatment in asthma. Curr Opin Allergy Clin Immunol. 2018;18(3):184–189. doi:10.1097/ACI.0000000000000440.
   PubMed Web of Science ®Google Scholar
• Mihaicuta S, Ursoniu S, Dumitriu D, Frent S, Fira-Mladinescu O, Tudorache V. Smoking as a predictor for losing control of treated bronchial asthma. Pneumologia. 2009;58(3):186–189.
   PubMedGoogle Scholar
• DiMango E, Rogers L, Reibman J, Gerald LB, Brown M, Sugar EA, Henderson R, Holbrook JT. Risk factors for asthma exacerbation and treatment failure in adults and adolescents with well-controlled asthma during continuation and step-down therapy. Ann Am Thorac Soc. 2018;15(8):955–961. doi:10.1513/AnnalsATS.201711-886OC.
   PubMed Web of Science ®Google Scholar
• Tiotiu A, Ioan I, Wirth N, Romero-Fernandez R, González-Barcala F-J. The impact of tobacco smoking on adult asthma outcomes. Int J Environ Res Public Health. 2021;18(3):992. doi:10.3390/ijerph18030992.
   PubMed Web of Science ®Google Scholar
• Kwon J-W, Jung H, Kim S-H, Chang Y-S, Cho YS, Nahm D-H, Jang A-S, Park J-W, Yoon HJ, Cho S-H, et al. High ACT score is not sufficient to reduce the risk of asthma exacerbations in asthma with low lung function. Respir Med. 2019;150:38–44. doi:10.1016/j.rmed.2019.02.010.
   PubMed Web of Science ®Google Scholar
• Tiotiu A, Labor M, Nedeva D, Novakova S, Oguzulgen IK, Mihaicuta S, Braido F. How to apply the personalized medicine in obesity-associated asthma? Expert Rev Respir Med. 2020;14(9):905–915. doi:10.1080/17476348.2020.1780123.
   PubMed Web of Science ®Google Scholar
• Henneberger PK, Redlich CA, Callahan DB, Harber P, Lemière C, Martin J, Tarlo SM, Vandenplas O, Torén K, ATS Ad Hoc Committee on Work-Exacerbated Asthma. An official American Thoracic Society statement: work-exacerbated asthma. Am J Respir Crit Care Med. 2011;184(3):368–378. doi:10.1164/rccm.812011ST.
   PubMed Web of Science ®Google Scholar
• Rui F, Otelea MR, Fell AK, Stoleski S, Mijakoski D, Holm M, Schlünssen V, Larese Filon F. Occupational asthma: the knowledge needs for a better management. Ann Work Expo Health. 2022;66(3):287–290. doi:10.1093/annweh/wxab113.
   PubMed Web of Science ®Google Scholar
• Bikov A, Oğuzülgen IK, Baiardini I, Contoli M, Emelyanov A, Fassio O, Ivancevich JC, Kaidashev I, Kowal K, Labor M, Interasma Scientific Network (INES), et al. Beliefs and preferences regarding biological treatments for severe asthma. World Allergy Organ J. 2020;13(7):100441. doi:10.1016/j.waojou.2020.100441.
   PubMed Web of Science ®Google Scholar
• Thoré P, Tiotiu A. Asthme professionnel non contrôlé: autour des comorbidités de l’asthme [Uncontrolled occupational asthma: talking about comorbidities]. Rev Mal Respir. 2019;36(5):633–637. doi:10.1016/j.rmr.2019.03.008.
   PubMedGoogle Scholar
• Tiotiu AI, Novakova P, Nedeva D, Chong-Neto HJ, Novakova S, Steiropoulos P, Kowal K. Impact of air pollution on asthma outcomes. Int J Environ Res Public Health. 2020;17(17):6212. doi:10.3390/ijerph17176212.
   PubMed Web of Science ®Google Scholar
• Tiotiu A. Applying personalized medicine to adult severe asthma. Allergy Asthma Proc. 2021;42(1):e8–e16. doi:10.2500/aap.2021.42.200100.
   PubMed Web of Science ®Google Scholar
• Schatz M, Camargo CA, Jr. The relationship of sex to asthma prevalence, health care utilization, and medications in a large managed care organization. Ann Allergy Asthma Immunol. 2003;91(6):553–558. doi:10.1016/S1081-1206(10)61533-5.
   PubMed Web of Science ®Google Scholar
• Han Y-Y, Forno E, Celedón JC. Sex steroid hormones and asthma in a nationwide study of US adults. Am J Respir Crit Care Med. 2020;201(2):158–166. doi:10.1164/rccm.201905-0996OC.
   PubMed Web of Science ®Google Scholar
• Guan D, Yuan W, Lee YK, Najeebullah K, Rasel MK. A review of ensemble learning based feature selection. IETE Technical Review. 2014;31(3):190–198. doi:10.1080/02564602.2014.906859.
   Web of Science ®Google Scholar
• Kazakova O, Racoviceanu R, Petrova A, Mioc M, Militaru A, Udrescu L, Udrescu M, Voicu A, Cummings J, Robertson G, et al. New investigations with Lupane type A-ring Azepane Triterpenoids for antimycobacterial drug candidate design. Int J Mol Sci. 2021;22(22):12542. doi:10.3390/ijms222212542.
   PubMed Web of Science ®Google Scholar
• Sit G, Varraso R, Fezeu LK, Galan P, Orsi F, Da Silva EP, Touvier M, Hercberg S, Paris C, Le Moual N, et al. Occupational exposures to irritants and sensitizers, asthma and asthma control in the NutriNet-Santé cohort. J Allergy Clin Immunol Pract. 2022;10(12):3220–3227.e7. doi:10.1016/j.jaip.2022.08.047.
   PubMed Web of Science ®Google Scholar
• Wark PA, Gibson PG. Asthma exacerbations·3: pathogenesis. Thorax. 2006;61(10):909–915. doi:10.1136/thx.2005.045187.
   PubMed Web of Science ®Google Scholar
• Le Moual N, Carsin A-E, Siroux V, Radon K, Norback D, Torén K, Olivieri M, Urrutia I, Cazzoletti L, Jacquemin B, et al. Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II. Eur Respir J. 2014;43(2):374–386. doi:10.1183/09031936.00034913.
   PubMed Web of Science ®Google Scholar
• Mapp CE, Boschetto P, Maestrelli P, Fabbri LM. Occupational asthma. Am J Respir Crit Care Med. 2005;172(3):280–305. doi:10.1164/rccm.200311-1575SO.
   PubMed Web of Science ®Google Scholar
• de Vocht F, Zock J-P, Kromhout H, Sunyer J, Antó JM, Burney P, Kogevinas M. Comparison of self‐reported occupational exposure with a job exposure matrix in an international community‐based study on asthma. Am J Ind Med. 2005;47(5):434–442. doi:10.1002/ajim.20154.
   PubMed Web of Science ®Google Scholar