Assessment of the in vivo genotoxicity of a new formulation of Bacillus thuringiensis var israelensis SH-14

References

• Avisar , D , Eilenberg , H , Keller , M , Reznik , N , Segal , M , Sneh , B and Zilberstein , A . 2009 . The Bacillus thuringiensis delta-endotoxin Cry1C as a potential bioinsecticide in plants . Plant Science , 176 : 315 – 24 .
   Google Scholar
• Bakare , AA , Mosuro , AA and Osibanjo , O . 2005 . An in vivo evaluation of induction of abnormal sperm morphology in mice by landfill leachates . Mutation Research , 582 : 28 – 34 .
   PubMed Web of Science ®Google Scholar
• Bernard , BK , Watanabe , E , Kodama , T , Tsubuku , S , Otabe , A , Nakajima , M Madoka , M . 2008 . Studies of the toxicological potential of capsinoids: V. genotoxicity studies of dihydrocapsiate . International Journal of Toxicology , 27 : 59 – 72 .
   PubMed Web of Science ®Google Scholar
• Broderick , N , Raffa , FK and Handelsman. , J . 2006. Midgut bacteria required for Bacillus thuringiensis insecticidal activity. Proceedings of the National Academy of Sciences 103: 15196–9
   Google Scholar
• Charles , JF and Nielsen-LeRoux , C . 2000 . Mosquitocidal bacterial toxins: Diversity, mode of action and resistance phenomena . Memorias do Instituto Oswaldo Cruz , 95 : 201 – 6 .
   Google Scholar
• de Barjac , H , Larget , I , Bénichou , L , Cosmao , V , Viviani , G , Ripouteau , H and Papion , S . 1980 . Test d’innocuité sur mammifères avec du sérotype H 14 de Bacillus thuringiensis , Geneva : World Health Organization .
   Google Scholar
• EPA 1996. OPPTS 885.3000 Background – Mammalian toxicity/pathogenicity/infectivity
   Google Scholar
• EPA 2000. Good laboratory practice standards, Code of Federal Regulations 40, Part 160
   Google Scholar
• Fenech , M , Holland , N , Chang , WP and Zeiger , E . 1999 . The human microNucleus project: An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans . Mutation Research , 428 : 271 – 83 .
   PubMed Web of Science ®Google Scholar
• Gill , M and Ellar , D . 2002 . Transgenic Drosophilia reveals a functional in vivo receptor for the Bacillus thuringiensis toxin cry 1Ac1 . Insect Molecular Biology , 11 : 619 – 25 .
   PubMed Web of Science ®Google Scholar
• Gollapudi , BB and McFadden , LG . 1995 . Sample size for the estimation of polychromatic to normochromatic erythrocyte ratio in the bone marrow micronucleus test . Mutation Research , 347 : 97 – 9 .
   PubMedGoogle Scholar
• Grisolia , CK , Oliveira-Filho , EC , Ramos , FR , Lopes , MC , Muniz , DHF and Monnerat , RG . 2009 . Acute toxicity and cytotoxicity of Bacillus thuringiensis and Bacillus sphaericus . Ecotoxicology , 18 : 22 – 6 .
   Google Scholar
• ICH 1999. International Conference on Harmonization Guidelines, Genotoxicity: A Standard Battery for Genotoxicity Testing of Pharmaceuticals, Step 4
   Google Scholar
• ILAR. 1996 . Guide for the care and use of laboratory animals , New York : National Academy Press .
   Google Scholar
• Klaassen , CD and Rozman , K . 1991 . “ Absorption, distribution, and excretion of toxicants ” . In Toxicology: The basic science of poisons, , 50 – 57 . New York : Pergamon Press .
   Google Scholar
• Krishna , G and Hayashi , M . 2000 . In vivo rodent micronucleus assay: Protocol, conduct and data interpretation . Mutation Research , 455 : 155 – 66 .
   PubMed Web of Science ®Google Scholar
• Lacey , LA , Frutos , R , Kaya , HK and Vail , P . 2001 . Insect pathogens as biological control agents: Do they have a future? . Biological Control , 21 : 230 – 48 .
   Web of Science ®Google Scholar
• Legator , MS , Palmer , KA , Green , S and Petersen , KW . 1969 . Cytogenetic studies in rats of cyclohexylamine, a metabolite of cyclamate . Science , 165 : 1139 – 40 .
   PubMed Web of Science ®Google Scholar
• Mancebo , A , González , B , Riera , L , Lugo , S , González , Y , Arteaga , ME and Fuentes , D . 2003 . Toxicity/pathogenicity evaluation of a Bacillus thuringiensis var israelensis formulation (Bactivec) . Revista de Toxicología , 20 : 204 – 9 .
   Google Scholar
• McClintock , JT , Schaffer , CR , Kough , JL and Sjoblad , RD . 1995b . “ Relevant taxonomic considerations for regulation of Bacillus thuringiensis-based pesticides by the US Environmental Protection Agency ” . In Bacillus thuringiensis. Biotechnology and environmental benefits , Edited by: Feng , TY . 313 – 25 . Taiwan : Hua Shiang Yuan Publishing Co .
   Google Scholar
• McClintock , JT , Schaffer , CR and Sjoblad , RD . 1995a . A comparative review of the mammalian toxicity of Bacillus thuringiensis-based pesticides . Pesticide Sciences , 45 : 95 – 105 .
   Google Scholar
• Moore , FR , Urda , GA , Krishna , G and Thesis , JC . 1996 . Genotoxicity evaluation of selenium sulfide in vivo and in vitro micronucleus and chromosome aberration assays . Mutation Research , 367 : 33 – 41 .
   Google Scholar
• Noteborn , H , Bienenmann-Ploum , ME , van den Berg , JHJ , Alink , GM , Zolla , L , Reynaerts , A , Pensa , M and Kuiper , HA . 1995 . “ Safety assessment of the Bacillus thuringiensis insecticidal crystal protein CRYIA(b) expressed in transgenic tomato ” . In Genetically modified foods: Safety issues , Edited by: Engel , K-H , Takeoka, , GR and Teranishi , R . 134 – 47 . Washington, DC : American Chemical Society .
   Google Scholar
• OECD 1997a. TG 474: Mammalian erythrocyte micronucleus test. France: Organization for Economic Co-Operation and Development
   Google Scholar
• OECD 1997b. TG 475: Mammalian bone marrow chromosome aberration test. France: Organization for Economic Co-Operation and Development
   Google Scholar
• Otubanjo , OA and Mosuro , AA . 2007 . An in vivo evaluation of the induction of abnormal sperm morphology by Sulphamethoxypyridazine: Pyrimethamine (Metakelfin) . Pakistan Journal of Biological Sciences , 10 : 156 – 9 .
   Google Scholar
• Pérez-Rivera , AA , Hu , T , Aardema , MJ and Nash , JF . 2009 . Evaluation of the genotoxicity of the imidazole antifungal climbazole: Comparison to published results for other azole compounds . Mutation Research , 672 : 27 – 39 .
   PubMed Web of Science ®Google Scholar
• Preston , RJ , Dean , BJ , Galloway , S and Holden , H . 1987 . Mammalian in vivo cytogenetic assays. Analysis of chromosome aberrations in bone marrow cells . Mutation. Research , 189 : 157 – 65 .
   PubMed Web of Science ®Google Scholar
• Salam , AE , Hussein , EH , El-Itriby , HA , Anwar , WA and Mansour , SA . 1993 . The mutagenecity of Gamaxone on different eukaryotic system . Mutation Research , 319 : 89 – 101 .
   PubMed Web of Science ®Google Scholar
• Schmid , W . 1975 . The micronucleus test . Mutation Research , 31 : 9 – 15 .
   PubMed Web of Science ®Google Scholar
• Schnepf , E , Crickmore , N , Van Rie , J , Lereclus , D , Baum , J , Feitelson , J , Zeigler , DR and Dean , DH . 1998 . Bacillus thuringiensis and its pesticidal crystal proteins . Microbiology and Molecular Biology Reviews , 62 : 775 – 806 .
   PubMed Web of Science ®Google Scholar
• Shadduck , JA . 1980 . Bacillus thuringiensis serotype H-14 maximum challenge and eye irritation safety tests in mammals , Geneva : World Health Organization .
   Google Scholar
• Shahabuddin , MS and Gopal , M . 2007 . Genotoxicity of DNA intercalating anticancer drugs: Pyrimidol [4I,SI:4,5] thieno (2,3-b) quinolines on somatic and germinal cells . Toxicology Mechanisms and Methods , 17 : 135 – 45 .
   PubMed Web of Science ®Google Scholar
• Siegel , JP . 2001 . The mammalian safety of Bacillus thuringiensis-based insecticides . Journal of Invertebrate Pathology , 77 : 13 – 21 .
   PubMed Web of Science ®Google Scholar
• Siegel , JP , Shadduck , JA and Szabo , J . 1987 . Safety of the entomopathogen Bacillus thuringiensis var. israelensis for mammals . Journal of Economic Entomology , 80 : 717 – 23 .
   PubMed Web of Science ®Google Scholar
• SPSS Statistical Package Scientific System for Windows. 1997. version 10.0.5, Copyright SPSS Inc., 1997
   Google Scholar
• Wyrobek , AJ and Bruce. , WR . 1975. Chemical induction of sperm-head abnormalities in mice. Proceedings of the National Academy of Sciences 72: 4425–9
   Google Scholar