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Articles

Examining the ability of empirical correlations to predict subject specific in vivo extrathoracic aerosol deposition during tidal breathing

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Pages 363-376 | Received 16 Sep 2016, Accepted 10 Nov 2016, Published online: 18 Dec 2016

References

  • Ball, C. G., Uddin, M., and Pollard, A. (2008). Mean Flow Structures Inside the Human Upper Airway. Flow Turbulence Combust., 81(1–2):155–188. doi: 10.1007/s10494-007-9113-3
  • Borgstrom, L., Olsson, B., and Thorsson, L. (2006). Degree of Throat Deposition Can Explain the Variability in Lung Deposition of Inhaled Drugs. J. Aerosol Med., 19(4):473–483. doi: 10.1089/jam.2006.19.473
  • Brancatisano, T., Collett, P. W., and Engel, L. A. (1983). Respiratory Movements of the Vocal Cords. J. Appl. Physiol. Respir. Environ. Exerc. Physiol., 54(5):1269–1276
  • Buckingham, E. (1914). On Physically Similar Systems, Illustrations of the Use of Dimensional Equations. Phys. Rev., 4(4):345–376. doi: Doi10.1103/Physrev.4.345
  • Cheng, Y. S. (2003). Aerosol Deposition in the Extrathoracic Region. Aerosol Sci. Technol., 37(8):659–671. doi: 10.1080/02786820300906
  • Cheng, Y. S., Zhou, Y., and Su, W. C. (2015). “Deposition of Particles in Human Mouth-Throat Replicas and a USP Induction Port. J. Aerosol Med. Pulm. Drug Deliv., 28(3):147–155. doi: 10.1089/jamp.2013.1105
  • Delvadia, R., Hindle, M., Longest, P. W., and Byron, P. R. (2013). In Vitro Tests for Aerosol Deposition II: IVIVCs for Different Dry Powder Inhalers in Normal Adults. J. Aerosol Med. Pulm. Drug Deliv., 26(3):138–144. doi: 10.1089/jamp.2012.0975
  • Delvadia, R. R., Longest, P. W., and Byron, P. R. (2012). In Vitro Tests for Aerosol Deposition. I: Scaling a Physical Model of the Upper Airways to Predict Drug Deposition Variation in Normal Humans. J. Aerosol. Med. Pulm. Drug Deliv., 25(1):32–40. doi: 10.1089/jamp.2011.0905
  • Eberl, S., Chan, H. K., Daviskas, E., Constable, C., and Young, I. (2001). Aerosol Deposition and Clearance Measurement: A Novel Technique Using Dynamic SPET. Eur. J. Nucl. Med., 28(9):1365–1372. doi: DOI10.1007/s002590100586
  • Eccovision. (2008). ECCOVISION Acoustic Pharyngometry Operator Manual. Sleep Group Solutions, Hollywood, Florida.
  • Ehtezazi, T., Southern, K. W., Allanson, D., Jenkinson, I., and O'Callaghan, C. (2005). Suitability of the Upper Airway Models Obtained from MRI Studies in Simulating Drug Lung Deposition from Inhalers. Pharmaceutical Res., 22(1):166–170. doi: 10.1007/s11095-004-9023-1
  • Finlay, W. H. (2001). Mechanics of Inhaled Pharmaceutical Aerosols—An Introduction. Academic Press, San Diego, CA, USA
  • Finlay, W. H., and Martin, A. R. (2008). Recent Advances in Predictive Understanding of Respiratory Tract Deposition. J. Aerosol. Med. Pulm. Drug Deliv., 21(2):189–206. doi: 10.1089/jamp.2007.0645
  • Fleming, J., Bailey, D. L., Chan, H.-K., Conway, J., Kuehl, P. J., Laube, B. L., and Newman, S. (2012). Standardization of Techniques for Using Single-Photon Emission Computed Tomography (SPECT) for Aerosol Deposition Assessment of Orally Inhaled Products. J. Aerosol Med. Pulm. Drug Deliv., 25(Suppl 1):S29–S51
  • Foord, N., Black, A., and Walsh, M. (1978). Regional Deposition of 2.5–7.5 μm Diameter Inhaled Particles in Healthy Male Non-Smokers. J. Aerosol Sci., 9(4):343–357. doi: 10.1016/0021-8502(78)90037-x
  • Golshahi, L., and Finlay, W. H. (2012). An Idealized Child Throat that Mimics Average Pediatric Oropharyngeal Deposition. Aerosol Sci. Technol., 46(5):I–IV. doi: 10.1080/02786826.2012.667170
  • Golshahi, L., Noga, M. L., Vehring, R., and Finlay, W. H. (2013). An In Vitro Study on the Deposition of Micrometer-Sized Particles in the Extrathoracic Airways of Adults During Tidal Oral Breathing.” Ann. Biomed. Eng., 41(5):979–989. doi: 10.1007/s10439-013-0747-0
  • Grgic, B., Finlay, W. H., Burnell, P. K. P., and Heenan, A. F. (2004). In Vitro Intersubject and Intrasubject Deposition Measurements in Realistic Mouth-Throat Geometries. J. Aerosol Sci., 35(8):1025–1040. doi: 10.1016/j.jaerosci.2004.03.003
  • Grgic, B., Finlay, W. H., and Heenan, A. F. (2004). Regional Aerosol Deposition and Flow Measurements in an Idealized Mouth and Throat. J. Aerosol Sci., 35(1):21–32. doi: 10.1016/S0021-8502(03)00387-2
  • Heenan, A. F., Finlay, W. H., Grgic, B., Pollard, A., and Burnell, P. K. P. (2004). An Investigation of the Relationship Between the Flow Field and Regional Deposition in Realistic Extra-Thoracic Airways. J. Aerosol Sci., 35(8):1013–1023. doi: 10.1016/j.jaerosci.2004.03.004
  • Heyder, J., Gebhart, J., Stahlhofen, W., and Stuck, B. (1982). Biological Variability of Particle Deposition in the Human Respiratory Tract During Controlled and Spontaneous Mouth-Breathing. Ann. Occup. Hyg., 26(1–4):137–147. doi: 10.1093/annhyg/26.1.137
  • Hinds, W. C. (1999). Aerosol Technology: Properties, Behavior, and Measurement of Airborne Particles. Wiley, New York.
  • International Commission on Radiological Protection (1994). ICRP Publication 66: Human Respiratory Tract Model for Radiological Protection. Vol. 24: Pergamon, Oxford, UK.
  • Jahani, N., Choi, S., Choi, J., Iyer, K., Hoffman, E. A., and Lin, C. L. (2015). Assessment of Regional Ventilation and Deformation Using 4D-CT Imaging for Healthy Human Lungs During Tidal Breathing. J. Appl. Physiol., 119(10):1064–1074. doi: 10.1152/japplphysiol.00339.2015
  • Javaheri, E., Shemirani, F. M., Pichelin, M., Katz, I. M., Caillibotte, G., Vehring, R., and Finlay, W. H. (2013). Deposition Modeling of Hygroscopic Saline Aerosols in the Human Respiratory Tract: Comparison Between Air and Helium–Oxygen as Carrier Gases. J. Aerosol Sci., 64:81–93. doi: http://dx.doi.org/10.1016/j.jaerosci.2013.04.010
  • Katz, I., Pichelin, M., Caillibotte, G., Montesantos, S., Majoral, C., Martonen, T., Fleming, J., Bennett, M., and Conway, J. (2013). Controlled, Parametric, Individualized, 2D, and 3D Imaging Measurements of Aerosol Deposition in the Respiratory Tract of Healthy Human Subjects: Preliminary Comparisons with Simulations. Aerosol Sci. Technol., 47(7):714–723. doi: 10.1080/02786826.2013.784393
  • Longest, P. W., and Holbrook, L. T. (2012). In Silico Models of Aerosol Delivery to the Respiratory Tract—Development and Applications. Adv. Drug Deliv. Rev., 64(4):296–311. doi: 10.1016/j.addr.2011.05.009
  • Mitchell, J. P., Nagel, M. W., Nichols, S., and Nerbrink, O. (2006). Laser Diffractometry as a Technique for the Rapid Assessment of Aerosol Particle Size from Inhalers. J. Aerosol Med., 19(4):409–433. doi: 10.1089/jam.2006.19.409
  • Miyawaki, S., Hoffman, E. A., and Lin, C.-L. (2016). Effect of Static vs. Dynamic Imaging on Particle Transport in CT-Based Numerical Models of Human Central Airways. J. Aerosol Sci., 100:129–139. doi: 10.1016/j.jaerosci.2016.07.006
  • Nehmeh, S. A., Erdi, Y. E., Ling, C. C., Rosenzweig, K. E., Schoder, H., Larson, S. M., Macapinlac, H. A., Squire, O. D., and Humm, J. L. (2002). Effect of Respiratory Gating on Quantifying PET Images of Lung Cancer. J. Nucl. Med., 43(7):876–881.
  • Nicolaou, L., and Zaki, T. A. (2013). Direct Numerical Simulations of Flow in Realistic Mouth-Throat Geometries. J. Aerosol Sci., 57:71–87. doi: 10.1016/j.jaerosci.2012.10.003
  • Rivlin, J., Hoffstein, V., Kalbfleisch, J., McNichols, W., Zamel, N., and Bryan, A. C. (1985). Upper Airway Morphology in Patients with Idiopathic Obstructive Sleep Apnea. Surv. Anesthesiol., 29(1):42.
  • Roth, A. P., Lange, C. F., and Finlay, W. H. (2003). The Effect of Breathing Pattern on Nebulizer Drug Delivery. J. Aerosol Med., 16(3):325–339. doi: 10.1089/089426803769017677
  • Rudolf, G., Gebhart, J., Heyder, J., Scheuch, G., and Stahlhofen, W. (1988). Mass Deposition from Inspired Polydisperse Aerosols. Ann. Occup. Hyg., 32(inhaled particles VI):919–938. doi: 10.1093/annhyg/32.inhaled_particles_VI.919
  • Rudolf, G., Kobrich, R., and Stahlhofen, W. (1990). Modeling and Algebraic Formulation of Regional Aerosol Deposition in Man. J. Aerosol Sci., 21 (Suppl. 1):S403–S406. doi: Doi10.1016/0021-8502(90)90266-Z
  • Sandeau, J., Katz, I., Fodil, R., Louis, B., Apiou-Sbirlea, G., Caillibotte, G., and Isabey, D. (2010). CFD Simulation of Particle Deposition in a Reconstructed Human Oral Extrathoracic Airway for Air and Helium–Oxygen Mixtures. J. Aerosol Sci., 41(3):281–294. doi: http://dx.doi.org/10.1016/j.jaerosci.2009.12.001
  • Scheinherr, A., Bailly, L., Boiron, O., Lagier, A., Legou, T., Pichelin, M., Caillibotte, G., and Giovanni, A. (2015). Realistic Glottal Motion and Airflow Rate During Human Breathing. Med. Eng. Phys., 37(9):829–839. doi: 10.1016/j.medengphy.2015.05.014
  • Shinneeb, A. M., and Pollard, A. (2012). Investigation of the Flow Physics in the Human Pharynx/Larynx Region. Exp. Fluids, 53(4):989–1003. doi: 10.1007/s00348-012-1336-y
  • Stahlhofen, W., Rudolf, G., and James, A. C. (1989). Intercomparison of Experimental Regional Aerosol Deposition Data. J. Aerosol Med., 2(3):285–308
  • Stapleton, K. W., Guentsch, E., Hoskinson, M. K., and Finlay, W. H. (2000). On the Suitability of k-Epsilon Turbulence Modeling for Aerosol Deposition in the Mouth and Throat: A Comparison with Experiment. J. Aerosol Sci., 31(6):739–749. doi: 10.1016/S0021-8502(99)00547-9
  • United States Pharmacopeia. (2011). Physical Tests and Determinations. <601>Aerosols, Nasal Sprays, Metered-Dose Inhalers, and Dry Powder Inhalers. United States Pharmacopeia, Rockville, Maryland, pp. 232–254
  • Xi, J., Yuan, J. E., Yang, M., Si, X., Zhou, Y., and Cheng, Y. Z. (2016). Parametric Study on Mouth–Throat Geometrical Factors on Deposition of Orally Inhaled Aerosols. J. Aerosol Sci., 99:94–106. doi: 10.1016/j.jaerosci.2016.01.014

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