Numerical modeling of particle deposition in ferret airways: A comparison with humans

References

• Albuquerque-Silva, I., Vevellio, L., Durand, M., Avet, J., Pennec, D. L., Monte, M. D., Montharu, J., Diot, P., Cottier, M., Dubois, F., and Pourchez, J. (2014). Particle Deposition in a Child Respiratory Tract Model: In-vivo Regional Deposition Fine and Ultrafine Aerosols in Baboons. PLoS ONE, 9:e95456.
   PubMed Web of Science ®Google Scholar
• Asgharian, B., Price, O., McClellan, G., Corley, R., Einstein, D. R., Jacob, R. E., Harkema, J., Carey, S. A., Schelegle, E., Hyde, D., Kumbell, J. S., and Miller, F. J. (2012). Development of a Rhesus Monkey Lung Geometry Model and Application to Particle Deposition in Comparison to Humans. Inhal. Toxicol., 24:869–899.
   PubMed Web of Science ®Google Scholar
• Balásházy, I., Hofmann, W., and Heistracher, T. (2003). Local Particle Deposition Patterns May Play a Key Role in the Development of Lung Cancer. J. Appl. Physiol., 94:1719–1725.
   PubMed Web of Science ®Google Scholar
• Barrett, K. E, Barman, S. M, Boitano, S., and Brooks, H. (2012). Ganong's Review of Medical Physiology. 24th ed., McGraw–Hill, New York, pp. 619.
   Google Scholar
• Belser, J. A, Katz, J. M., Tumpey, T. M. (2011). The Ferret as a Model Organism to Study Influenza A Virus Infection. Dis. Model Mech., 4:575–579.
   PubMed Web of Science ®Google Scholar
• Bouvier, N. M., and Lowen, A. C. (2010). Animal Models for Influenza Virus Pathogenesis and Transmission. Viruses, 2:1530–1563.
   PubMed Web of Science ®Google Scholar
• Bouvier, N. M., Lowen, A. C., and Palese, P. (2008). Oseltamivir-Resistant Influenza A Viruses are Transmitted Efficiently Among Guinea Pigs by Direct Contact But Not by Aerosol. J. Virol., 82:10052–10058.
   PubMed Web of Science ®Google Scholar
• Cohen, B., Sussman, R., and Lippmann, M. (1990). Ultrafine Particle Deposition in a Human Tracheobronchial Cast. Aerosol Sci. Technol., 12:1082–1091.
   Web of Science ®Google Scholar
• Corley, R., Kabilan, S., Kuprat, A., Carson, J., Minard, K., Jacob, R., Timchalk, C., Glenny, R., Pipavath, S., Cox, T., WALLIS, C., Larson, R., Fanucchi, M., Postlethwait, E., and Einstein, D. (2012). Comparative Computational Modeling of Airflows and Vapor Dosimetry in the Respiratory Tracts of a Rat, Monkey, and Human. Toxicol. Sci., 128:500–516.
   PubMed Web of Science ®Google Scholar
• Fishler, R., Hofemeier, P., Etzion, Y., Dubowski, Y., and Sznitman, J. (2015). Particle Dynamics and Deposition in True-Scale Pulmonary Acinar Models. Sci. Rep., 5(14071):1–11.
   PubMed Web of Science ®Google Scholar
• Gabriel, G., Dauber, B., Wolff, T., Planz, O., Klenk, H.-D., and Stech, J. (2005). The Viral Polymerase Mediates Adaptation of an Avian Influenza Virus to a Mammalian Host. Proc. Natl. Acad. Sci. USA, 102:18590–18595.
   PubMed Web of Science ®Google Scholar
• Gattinoni, L., Chiumello, D., and Russo, R. (2002). Reduced Tidal Volumes and Lung Protective Ventilatory Strategies: Where Do We Go From Here? Curr. Opin. Crit. Care., 8:45–50.
   PubMedGoogle Scholar
• Gemci, T., Ponyavin, V., Chen, Y., Chen, H., and Collins, R. (2008). Computational Model of Airflow in Upper 17 Generations of Human Respiratory Tract. J. Biomech., 41:2047–2054.
   PubMed Web of Science ®Google Scholar
• Gustin, K. M., Belser, J. A., Wadford, D. A., Pearce, M. B., Katz, J. M., Tumpey, T. M., and Maines, T. R. (2011). Influenza Virus Aerosol Exposure and Analytical System for Ferrets. Proc. Natl. Acad. Sci. USA, 108:8432–8437.
   PubMed Web of Science ®Google Scholar
• Guyton, A. C. (1947). Measurement of the Respiratory Volumes of Laboratory Animals. Am. J. Physiol., 150:70–77.
   PubMed Web of Science ®Google Scholar
• Haider, A., and Levenspiel, O. (1989). Drag Coefficient and Terminal Velocity of Spherical and Nonspherical Particles. Powder Technol., 58:63–70.
   Web of Science ®Google Scholar
• Herfst, S., Schrauwen, E. J. A., Linster, M., Chutinimitkul, S., de Wit, E., Munster, V. J., Sorrell, E. M., Bestebroer, T. M., Burke, D. F., Smith, D. J., Rimmelzwaan, G. F., Osterhaus, A. D., and Fouchier, R. A. (2012). Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets. Science, 336:1534–1541.
   PubMed Web of Science ®Google Scholar
• Heyder, J. (2004). Deposition of Inhaled Particles in the Human Respiratory Tract and Consequences of Regional Targeting in Respiratory Drug Delivery. Proc. Am. Thorac. Soc., 1:315–320.
   PubMedGoogle Scholar
• Hinds, W. C. (1999). Aerosol Technology: Properties, Behavior, and Measurement of Airborne Particles. 2nd ed. J. Wiley, New York, pp. 237–239.
   Google Scholar
• Hofmann, W. (2011). Modelling Inhaled Particle Deposition in the Human Lung: A Review. J. Aerosol Sci., 42:693–724.
   Web of Science ®Google Scholar
• Hussain, M., Madl, P., and Khan, A. (2011). Lung Deposition Predictions of Airborne Particles and Emergence of Contemporary Diseases Part-I. The Health, 2:51–59.
   Google Scholar
• International Commission on Radiological Protection (ICRP). (1994). ICRP Publication 66 Human Respiratory Tract Model for Radiological Protection. Pergamon, Oxford.
   Google Scholar
• Isaacs, K. K., and Martonen, T. B. (2005). Particle Deposition in Children's Lungs: Theory and Experiment. J. Aerosol Med., 18:337–353.
   PubMedGoogle Scholar
• Jia, N., Barclay, W. S., Roberts, K., Yen, H.-L., Chan, R. W. Y., Lam, A. K., Air, G., Peiris, J. S., Dell, A., Nicholls, J. M., and Haslam, S. M. (2014). Glycomic Characterization of Respiratory Tract Tissues of Ferrets. J. Biol. Chem., 289:28489–28504.
   PubMed Web of Science ®Google Scholar
• Kelly, J. T., Asgharian, B., and Wong, B. A. (2005). Inertial Particle Deposition in a Monkey Nasal Mold Compared with That in Human Nasal Replicas. Inhal. Toxicol., 17:823–830.
   PubMed Web of Science ®Google Scholar
• Kim, C. S., and Fisher, D. M. (1999). Deposition Characteristics of Aerosol Particles in Sequentially Bifurcating Airway Models. Aerosol Sci. Technol., 31:198–220.
   Web of Science ®Google Scholar
• Kleiber, M. (1932). Body Size and Metabolism. Hilgardia, 6:315–351.
   Google Scholar
• Kleinstreuer, C., Zhang, Z., and Kim, C. S. (2007). Combined Inertial and Gravitational Deposition of Microparticles in Small Model Airways of a Human Respiratory System. J. Aerosol Sci., 38:1047–1061.
   Web of Science ®Google Scholar
• Kolanjiyil, A. V., and Kleinstreuer, C. (2013). Nanoparticle Mass Transfer from Lung Airways to Systemic Regions, Part I: Whole-Lung Aerosol Dynamics. J. Biomech. Eng., 135:121003.
   PubMed Web of Science ®Google Scholar
• Lambert, L. C., and Fauci, A. S. (2010). Influenza Vaccines for the Future. N. Engl. J. Med., 363:2036–2044.
   PubMed Web of Science ®Google Scholar
• Lindsley, W. G., Pearce, T. A., Hudnall, J. B., Davis, K. A., Davis, S. M., Fisher, M. A., Khakoo, R., Palmer, J. E., Clark, K. E., Celik, I., Coffey, C. C., Blachere, F. M., and Beezhold, D. H. (2012). Quantity and Size Distribution of Cough-Generated Aerosol Particles Produced by Influenza Patients During and After Illness. J. Occup. Environ. Hyg., 9:443–449.
   PubMed Web of Science ®Google Scholar
• Longest, P. W., and Vinchurkar, S. (2007). Effects of Mesh Style and Grid Convergence on Particle Deposition in Bifurcating Airway Models with Comparisons to Experimental Data. Med. Eng. Phys., 29:350–366.
   PubMed Web of Science ®Google Scholar
• Lowen, A. C., Mubareka, S., Tumpey, T. M., Garcia-Sastre, A., and Palese, P. (2006). The Guinea Pig as a Transmission Model for Human Influenza Viruses. Proc. Natl. Acad. Sci. USA, 103:9988–9992.
   PubMed Web of Science ®Google Scholar
• Maines, T. R., Chen, L. M., Matsuoka, Y., Chen, H. L., Rowe, T., Ortin, J., Falcon, A., Hien, N. T., Mai, L. Q., Sedyaningsih, E. R., Harun, S., Tumpey, T. M., Donis, R. O., Cox, N. J., Subbarao, K., and Katz, J. M. (2006). Lack of Transmission of H5N1 Avian-Human Reassortant Influenza Viruses in a Ferret Model. Proc. Natl. Acad. Sci. USA, 103:12121–12126.
   PubMed Web of Science ®Google Scholar
• Maines, T. R., Jayaraman, A., Belser, J. A., Wadford, D. A., Pappas, C., Zeng, H., Gustin, K. M., Pearce, M. B., Viswanathan, K., Shriver, Z. H., Raman, R., Cox, N. J., Sasisekharan, R., Katz, J. M., and Tumpey, T. M. (2009). Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice. Science, 325:484–487.
   PubMed Web of Science ®Google Scholar
• Martin, A. R., and Finlay, W. H. (2007). A General, Algebraic Equation for Predicting Total Respiratory Tract Deposition of Micrometer-Sized Aerosol Particles in Humans. J. Aerosol Sci., 38:246–253.
   Web of Science ®Google Scholar
• Matrosovich, M. N., Matrosovich, T. Y., Gray, T., Roberts, N. A., and Klenk, H. (2004). Human and Avian Influenza Viruses Target Different Cell Types in Cultures of Human Airway Epithelium. Proc. Natl. Acad. Sci. USA, 101:4620–4624.
   PubMed Web of Science ®Google Scholar
• McMahon, T. A., Brian, J. D., and Lemott, S. (1975). Species Differences in Aerosol Deposition. Inhaled Part, 4:23–33.
   PubMedGoogle Scholar
• Milton, D. K., Fabian, M. P., Cowling, B. J., Grantham, M. L., and McDevitt, J. J. (2013). Influenza Virus Aerosols in Human Exhaled Breath: Particle Size, Culturability, and Effect of Surgical Masks. PLoS Pathog., 9:e1003205.
   PubMed Web of Science ®Google Scholar
• Morsi, S. A., and Alexander, A. J. (1972). An Investigation of Particle Trajectories in Two-Phase Flow Systems. J. Fluid Mech., 55:193–208.
   Web of Science ®Google Scholar
• National Council on Radiation Protection and Measurement (NCRP). (1997). Deposition, Retention and Dosimetry of Inhaled Radioactive Substances. NCRP S.C. 57–2 Report, Bethesda.
   Google Scholar
• Ng, P. S. K., Böhm, R., Hartley-Tassell, L. E., Steen, J. A., Wang, H., Lukowski, S. W., Hawthorne, P. L., Trezise, A. E., Coloe, P. J., Grimmond, S. M., Haselhorst, T., von Itzstein, M., Paton, A. W., Paton, J. C., and Jennings, M. P. (2014). Ferrets Exclusively Synthesize Neu5Ac and Express Naturally Humanized Influenza A Virus Receptors. Nat. Commun., 5:5750.
   PubMed Web of Science ®Google Scholar
• Nicholls, J. M., Chan, M. C. W., Chan, W. Y., Wong, H. K., Cheung, C. Y., Kwong, D. L. W., Wong, M. P., Chui, W. H., Poon, L. L., Tsao, S. W., Guan, Y., and Peiris, J. S. (2007). Tropism of Avian Influenza A (H5N1) in the Upper and Lower Respiratory Tract. Nat. Med., 13:147–149.
   PubMed Web of Science ®Google Scholar
• Nowak, N., Kakade, P. P., and Annaparagada, A. V. (2003). Computational Fluid Dynamics Simulation of Airflow and Aerosol Deposition in Human Lungs. Ann. Biomed. Eng., 31:374–390.
   PubMed Web of Science ®Google Scholar
• Oakes, J. M., Breen, E., Scadeng, M., Tchantchou, G. S., and Darquenne, C. (2014). MRI-Based Measurements of Aerosol Deposition in the Lung of Healthy and Elastase-Treated Rats. J. Appl. Physiol., 116:1561–1568.
   PubMed Web of Science ®Google Scholar
• Oakes, J. M., Marsden, A. L., Grandmont, C., Darquenne, C., and Vignon-Clemental, I. E. (2015). Distribution of Aerosolized Particles in Healthy and Emphysematous Rat Lungs: Comparision Between Experimental and Numerical Studies. J. Biomech., 48:1147–1157.
   PubMed Web of Science ®Google Scholar
• Oldham, M. J., Phalen, R. F., and Huxtable, R. F. (1990). Growth of the Ferret Tracheobronchial Tree. Lab. Animal Sci., 40:186–191.
   PubMedGoogle Scholar
• Ottolini, M. G., Blanco, J. C. G., Eichelberger, M. C., Porter, D. D., Pletneva, L., Richardson, J. Y., and Prince, G. A. (2005). The Cotton Rat Provides a Useful Small-Animal Model for the Study of Influenza Virus Pathogenesis. J. Gen. Virol., 86:2823–2830.
   PubMed Web of Science ®Google Scholar
• Patton, J. S., and Byron, P. R. (2007). Inhaling Medicines: Delivering Drugs to the Body Through the Lungs. Nat. Rev. Drug. Discov., 6:67–74.
   PubMed Web of Science ®Google Scholar
• Phalen, R. F., Oldham, M. J., and Wolff, R. K. (2008). The Relevance of Animal Models for Aerosol Studies. J. Aerosol Med. Pulm. Drug Deliv., 21:113–124.
   PubMed Web of Science ®Google Scholar
• Shinya, K., Ebina, M., Yamada, S., Ono, M., Kasai, N., and Kawaoka, Y. (2006). Avian Flu: Influenza Virus Receptors in the Human Airway. Nature, 400:435–436.
   Web of Science ®Google Scholar
• Smith, W., Andrews, C. H., and Lardlaw, P. P. (1933). A Virus Obtained from Influenza Patients. Lancet, 222:66–68.
   Google Scholar
• Sturm, R. (2012). Modeling the Deposition of Bioaerosols with Variable Size and Shape in the Human Respiratory Tract-A Review. J. Adv. Res., 3:295–304.
   Google Scholar
• Tian, G., Longest, P. W., Su, G., Walenga, R. L., and Hindle, M. (2011). Development of a Stochastic Individual Path (SIP) Model for Predicting the Tracheobronchial Deposition of Pharmaceutical Aerosols: Effects of Transient Inhalation and Sampling the Airways. J. Aerosol Sci., 42:781–799.
   Web of Science ®Google Scholar
• Tian, G., Hindle, M., Lee, S., and Longest, P. W. (2015). Validating CFD Predictions of Pharmaceutical Aerosol Deposition with In Vivo Data. Pharm. Res., 32:3170–3187.
   PubMed Web of Science ®Google Scholar
• Vaish, M. (2015). A Lagrangian Approach for Calculating Microsphere Deposition in a One-Dimensional Lung-Airway Model. J. Biomech. Eng., 137:094502.
   Web of Science ®Google Scholar
• van Riel, D., den Bakker, M. A., Leijten, L. M. E., Chutinimitkul, S., Munster, V. J., de Wit, E., Rimmelzwaan, G. F., Fouchier, R. A., Osterhaus, A. D., and Kuiken, T. (2010). Seasonal and Pandemic Human Influenza Viruses Attach Better to Human Upper Respiratory Tract Epithelium than Avian Influenza Viruses. Am. J. Pathol., 174:1614–1618.
   Web of Science ®Google Scholar
• van Riel, D., Munster, V. J., de Wit, E., Rimmelzwaan, G. F., Fouchier, R. A. M., Osterhaus, A. D., and Kuiken, T. (2006). H5N1 Virus Attachment to Lower Respiratory Tract. Science, 312:399.
   PubMed Web of Science ®Google Scholar
• Walters, D. K., and Luke, W. H. (2010). A Method for Three-Dimensional Navier-Stokes Simulations of Large Scale Regions of the Human Lung Airway. J. Fluid Eng., 132:051101.
   Web of Science ®Google Scholar
• Walters, D. K., and Luke, W. H. (2011). Computational Fluid Dynamics Simulations of Particle Deposition in Large Scale, Multigenerational Lung Models. J. Biomech. Eng., 133:011003.
   PubMed Web of Science ®Google Scholar
• Wei, J., and Li, Y. (2016). Airborne Spread of Infectious Agents in the Indoor Environment. Am. J. Infect. Control, 44:S102–S108.
   PubMed Web of Science ®Google Scholar
• Weibel, E. R. (1963). Morphometry of the Human Lung. Academic, New York.
   Google Scholar
• Whary, M. T. (2014). In Physiology of the Ferret, in Biology and Diseases of the Ferret. Fox, J. G., and Marini, R. P., eds., 3rd ed., pp. 81–122.
   Google Scholar
• Winkler-Heil, R., Ferron, G., and Hofmann, W. (2014). Calculation of Hygroscopic Particle Deposition in the Human Lung. Inhal. Toxicol., 26:193–206.
   PubMed Web of Science ®Google Scholar
• Yang, X., Liu, Y., So, R., and Yang, J. (2006). The Effect of Inlet Velocity Profile on the Bifurcation COPD Airway Flow. Comput. Biol. Med., 36:181–194.
   PubMed Web of Science ®Google Scholar
• Zhou, Y., and Cheng, Y. -S. (2005). Particle Deposition in a Cast of Human Tracheobronchial Airways. Aerosol Sci. Technol., 39:492–500.
   Web of Science ®Google Scholar
• Zuuebier, M., Hoek, G., van den Hazel, P., and Brunekreef, B. (2009). Minute Ventilation of Cyclists, Car and Bus Passengers: An Experimental Study. Environ. Health, 8:48.
   PubMed Web of Science ®Google Scholar