Improved prediction of intersubject variability in extrathoracic aerosol deposition using algebraic correlations

References

• Castrup, S., and Castrup, H. T. (2010). Measurement Uncertainty Analysis Principles and Methods, in NASA Measurement Quality Assurance Handbook - ANNEX 3. National Aeronautic and Space Administration, Washington, DC.
   Google Scholar
• Chan, T. L., and Lippmann, M. (1980). Experimental Measurements and Empirical Modelling of the Regional Deposition of Inhaled Particles in Humans. Am. Ind. Hyg. Assoc. J., 41(6):399–409.
   PubMed Web of Science ®Google Scholar
• Cheng, Y. S., Zhou, Y., and Su, W. C. (2015). Deposition of Particles in Human Mouth-throat Replicas and a USP Induction Port. J. Aerosol Med. Pulm. Drug. Deliv., 28(3):147–155.
   PubMed Web of Science ®Google Scholar
• Clark, A. R., and Hartman, M. S. (2012). Regional Lung Deposition: Can it be Controlled and have an Impact on Safety and Efficacy? Resp. Drug Deliv. 2012, 1:89–100.
   Google Scholar
• Delvadia, R., Longest, P. W., and Byron, P. R. (2012). In Vitro Tests for Aerosol Deposition. I: Scaling a Physical Model of the Upper Airways to Predict Drug Deposition Variation in Normal Humans. J. Aerosol Med. Pulm. Drug Deliv., 25(1):32–40.
   PubMed Web of Science ®Google Scholar
• Finlay, W. H., and Martin, A. R. (2008). Recent Advances in Predictive Understanding of Respiratory Tract Deposition. J. Aerosol Med. Pulm. Drug Deliv., 21(2):189–206.
   PubMed Web of Science ®Google Scholar
• Golshahi, L., Noga, M. L., Vehring, R., and Finlay, W. H. (2013). An In Vitro Study on the Deposition of Micrometer-Sized Particles in the Extrathoracic Airways of Adults During Tidal Oral Breathing. Ann. Biomed. Eng., 41(5):979–989.
   PubMed Web of Science ®Google Scholar
• Grgic, B., Finlay, W. H., Burnell, P. K. P., and Heenan, A. F. (2004). In Vitro Intersubject and Intrasubject Deposition Measurements in Realistic Mouth-Throat Geometries. J. Aerosol Sci., 35(8):1025–1040.
   Web of Science ®Google Scholar
• Heenan, A. F., Finlay, W. H., Grgic, B., Pollard, A., and Burnell, P. K. P. (2004). An Investigation of the Relationship Between the Flow Field and Regional Deposition in Realistic Extra-Thoracic Airways. J. Aerosol Sci., 35(8):1013–1023.
   Web of Science ®Google Scholar
• Heyder, J., Gebhart, J., Stahlhofen, W., and Stuck, B. (1982). Biological Variability of Particle Deposition in the Human Respiratory Tract During Controlled and Spontaneous Mouth-Breathing. Ann. Occup. Hyg., 26(1):137–147.
   PubMed Web of Science ®Google Scholar
• International Commission on Radiological Protection. (1994). ICRP Publication 66: Human Respiratory Tract Model for Radiological Protection. Vol. 24. Pergamon, Oxford, UK.
   Google Scholar
• International Organization for Standardization. (2008). Guide 98-3:2008(E). Uncertainty of Measurement - Part 3: Guide to the Expression of Uncertainty in Measurement. International Organization for Standardization and International Electrotechnical Commission, Geneva, Switzerland.
   Google Scholar
• Katz, I., Pichelin, M., Caillibotte, G., Montesantos, S., Majoral, C., Martonen, T., Fleming, J., Bennett, M., and Conway, J. (2013). Controlled, Parametric, Individualized, 2D, and 3D Imaging Measurements of Aerosol Deposition in the Respiratory Tract of Healthy Human Subjects: Preliminary Comparisons with Simulations. Aerosol Sci. Technol., 47(7):714–723.
   Web of Science ®Google Scholar
• Lippmann, M., and Albert, R. E. (1969). The Effect of Particle Size on the Regional Deposition of Inhaled Aerosols in the Human Respiratory Tract. Am. Ind. Hyg. Assoc. J., 30(3):257–275.
   PubMedGoogle Scholar
• Lippmann, M. (1977). Regional Deposition of Particles in the Human Respiratory Tract, in Handbook of Physiology, Section 9 - Reactions to Environmental Agents, D. H. K. Lee, H. L. Falk, and S. D. Murphy, eds., American Physiological Society, Bethesda, Maryland, pp. 213–232.
   Google Scholar
• Olsson, B., Berg, E., and Svensson, M. (2010). Comparing Aerosol Size Distributions that Penetrate Mouth-Throat Models Under Realistic Inhalation Conditions. Resp. Drug Deliv. 2010, 1:225–234.
   Google Scholar
• Roth, A. P., Lange, C. F., and Finlay, W. H. (2003). The Effect of Breathing Pattern on Nebulizer Drug Delivery. J. Aerosol Med. Deposit. Clear. Eff. Lung, 16(3):325–339.
   PubMedGoogle Scholar
• Rudolf, G., Köbrich, R., Stahlhofen, W., and James, A. C. (1994). Regional Aerosol Deposition in Man-a Statistical and Algebraic Model. Ann. Occup. Hyg., 38:1–14.
   Google Scholar
• Sandeau, J., Katz, I., Fodil, R., Louis, B., Apiou-Sbirlea, G., Caillibotte, G., and Isabey, D. (2010). CFD Simulation of Particle Deposition in a Reconstructed Human Oral Extrathoracic Airway for Air and Helium-oxygen Mixtures. J. Aerosol Sci., 41(3):281–294.
   Web of Science ®Google Scholar
• Stapleton, K. W., Guentsch, E., Hoskinson, M. K., and Finlay, W. H. (2000). On the Suitability of k–ϵ Turbulence Modeling for Aerosol Deposition in the Mouth and Throat: A Comparison with Experiment. J. Aerosol Sci., 31(6):739–749.
   Web of Science ®Google Scholar
• Yang, M. Y., Ruzycki, C., Verschuer, J., Katsifis, A., Eberl, S., Wong, K., Golshahi, L., Brannan, J. D., Finlay, W. H., and Chan, H. K. (2017). Examining the Ability of Empirical Correlations to Predict Subject Specific in Vivo Extrathoracic Aerosol Deposition During Tidal Breathing. Aerosol Sci. Technol. 51(3):363–376.
   PubMed Web of Science ®Google Scholar