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Editorial

COVID-19 and the workplace: Research questions for the aerosol science community

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Pages 1117-1123 | Received 14 Jul 2020, Accepted 14 Jul 2020, Published online: 31 Jul 2020

References

  • Ahrenholz, S. H., S. E. Brueck, A. M. Rule, J. D. Noti, B. Noorbakhsh, F. M. Blachere, M. A. de Perio, W. G. Lindsley, R. E. Shaffer, and E. M. Fisher. 2018. Assessment of environmental and surgical mask contamination at a student health center—2012-2013 influenza season. J. Occup. Environ. Hyg. 15 (9):664–75. doi:10.1080/15459624.2018.1486509.
  • Aithinne, K. A. N., C. W. Cooper, R. A. Lynch, and D. L. Johnson. 2019. Toilet plume aerosol generation rate and environmental contamination following bowl water inoculation with Clostridium difficile spores. Am. J. Infect. Control. 47 (5):515–20. doi:10.1016/j.ajic.2018.11.009.
  • Anderson, E. L., P. Turnham, J. R. Griffin, and C. C. Clarke. 2020. Consideration of the aerosol transmission for COVID-19 and public health. Risk Anal. 40 (5):902–7. doi:10.1111/risa.13500.
  • Asadi, S., N. Bouvier, A. S. Wexler, and W. D. Ristenpart. 2020. The coronavirus pandemic and aerosols: Does COVID-19 transmit via expiratory particles? Aerosol Sci. Technol 54 (6):635–8. doi:10.1080/02786826.2020.1749229.
  • Asadi, S., A. S. Wexler, C. D. Cappa, S. Barreda, N. M. Bouvier, and W. D. Ristenpart. 2019. Aerosol emission and superemission during human speech increase with voice loudness. Sci. Rep. 9: 2348. doi:. 10.1038/s41598-019-38808-z.
  • Brady, T. M., A. L. Strauch, C. M. Almaguer, G. Niezgoda, R. E. Shaffer, P. L. Yorio, and E. M. Fisher. 2017. Transfer of bacteriophage MS2 and fluorescein from N95 filtering facepiece respirators to hands: Measuring fomite potential. J. Occup. Environ. Hyg. 14 (11):898–906. doi:10.1080/15459624.2017.1346799.
  • Callaway, E. 2020. Labs rush to study coronavirus in transgenic animals - some are in short supply. Nature 579 (7798):183. doi:10.1038/d41586-020-00698-x.
  • CDC. 2020a. How COVID-19 spreads. Accessed May 18, 2020. https://www.cdc.gov/coronavirus/2019-ncov/prepare/transmission.html.
  • CDC. 2020b. Interim infection prevention and control recommendations for patients with suspected or confirmed coronavirus disease 2019 (COVID-19) in healthcare settings. Accessed June 9, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/infection-control-recommendations.html.
  • CDC. 2020c. Worker-protective controls. engineering controls to reduce airborne, droplet and contact exposures during epidemic/pandemic response. Ventilated Headboard. Accessed May 22, 2020. https://www.cdc.gov/niosh/topics/healthcare/engcontrolsolutions/ventilated-headboard.html.
  • CDC. 2020d. Decontamination and reuse of filtering facepiece respirators. Accessed May 21, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/ppe-strategy/decontamination-reuse-respirators.html.
  • CDC. 2020e. Strategies for optimizing the supply of N95 respirators. Accessed May 11, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/respirators-strategy/index.html.
  • CDC. 2020f. Manufacturing workers and employers. Interim Guidance from CDC and the Occupational Safety and Health Administration (OSHA). Accessed May 22, 2020. https://www.cdc.gov/coronavirus/2019-ncov/community/guidance-manufacturing-workers-employers.html.
  • Chahal, A. M., K. Van Dewark, R. Gooch, E. Fukushima, and Z. M. Hudson. 2020. A rapidly deployable negative pressure enclosure for aerosol-generating medical procedures. MedRxiv (preprint) doi:10.1101/2020.04.14.20063958.
  • Chan, J. F., A. J. Zhang, S. Yuan, V. K. Poon, C. C. Chan, A. C. Lee, W. M. Chan, Z. Fan, H. W. Tsoi, L. Wen, et al. 2020. Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: Implications for disease pathogenesis and transmissibility. Clin. Infect. Dis. [published online ahead of print, 2020 Mar 26] doi:10.1093/cid/ciaa325.
  • Chen, Y., L. Chen, Q. Deng, G. Zhang, K. Wu, L. Ni, Y. Yang, B. Liu, W. Wang, C. Wei, et al. 2020. The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients. J. Med. Virol. [published online ahead of print, 2020 Apr 3]. doi:10.1002/jmv.25825.
  • Couper, K., S. Taylor-Phillips, A. Grove, K. Freeman, O. Osokogu, R. Court, A. Mehrabian, P. T. Morley, J. P. Nolan, J. Soar, et al. 2020. COVID-19 in cardiac arrest and infection risk to rescuers: A systematic review. Resuscitation 151:59–66. doi:10.1016/j.resuscitation.2020.04.022.
  • Deng, W., L. Bao, H. Gao, Z. Xiang, Y. Qu, Z. Song, S. Gong, J. Liu, J. Liu, P. Yu, et al. 2020. Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in Rhesus macaques. BioRxiv (Preprint). doi:10.1101/2020.03.13.990036.
  • Ding, Z., H. Qian, B. Xu, Y. Huang, T. Miao, H.-L. Yen, S. Xiao, L. Cui, X. Wu, W. Shao, et al. 2020. Toilets dominate environmental detection of SARS-CoV-2 virus in a hospital. MedRxiv (Preprint). doi:10.1101/2020.04.03.20052175.
  • Dungi, S. R., U. Ghia, K. R. Mead, and M. Gressel. 2015. Effectiveness of a local ventilation/filtration intervention for health-care worker exposure reduction to airborne infection in a hospital room. 2015 ASHRAE Winter Conference, Chicago, IL, American Society of Heating, Refrigeration and Air-Conditioning Engineers.
  • Gralton, J., E. Tovey, M. L. McLaws, and W. D. Rawlinson. 2011. The role of particle size in aerosolised pathogen transmission: A review. J. Infect. 62 (1):1–13. doi:10.1016/j.jinf.2010.11.010.
  • Hamner, L., P. Dubbel, I. Capron, A. Ross, A. Jordan, J. Lee, J. Lynn, A. Ball, S. Narwal, S. Russell, et al. 2020. High SARS-CoV-2 attack rate following exposure at a choir practice—Skagit County, Washington, March 2020. MMWR. Morb. Mortal. Wkly. Rep. 69 (19):606–10. doi:10.15585/mmwr.mm6919e6.
  • Harrel, S. K., and J. Molinari. 2004. Aerosols and splatter in dentistry: A brief review of the literature and infection control implications. J. Am. Dent. Assoc. 135 (4):429–37. doi:10.14219/jada.archive.2004.0207.
  • Hoffmann, M., H. Kleine-Weber, S. Schroeder, N. Kruger, T. Herrler, S. Erichsen, T. S. Schiergens, G. Herrler, N. H. Wu, A. Nitsche, et al. 2020. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 181 (2):271–80.e8. doi:10.1016/j.cell.2020.02.052.
  • Johnson, D. L., K. R. Mead, R. A. Lynch, and D. V. Hirst. 2013. Lifting the lid on toilet plume aerosol: A literature review with suggestions for future research. Am. J. Infect. Control. 41 (3):254–8. doi:10.1016/j.ajic.2012.04.330.
  • Judson, S. D., and V. J. Munster. 2019. Nosocomial transmission of emerging viruses via aerosol-generating medical procedures. Viruses 11 (10):940. doi:10.3390/v11100940.
  • Kim, Y. I., S. G. Kim, S. M. Kim, E. H. Kim, S. J. Park, K. M. Yu, J. H. Chang, E. J. Kim, S. Lee, M. A. B. Casel, et al. 2020. Infection and rapid transmission of SARS-CoV-2 in ferrets. Cell Host Microbe. 27 (5):704–9.e2. doi:10.1016/j.chom.2020.03.023.
  • Le, H. D., G. A. Novak, K. C. Janek, J. Wang, K. N. Huynh, C. Meyer, A. Weinstein, E. Oberstar, J. Rasmussen, and T. Bertram. 2020. A novel box for aerosol and droplet guarding and evacuation in respiratory infection (BADGER): A potential mitigating strategy for the COVID-19 pandemic and future outbreaks. MedRxiv (Preprint). doi:10.1101/2020.05.09.20096032.
  • Lindsley, W. G., J. D. Noti, F. M. Blachere, J. V. Szalajda, and D. H. Beezhold. 2014. Efficacy of face shields against cough aerosol droplets from a cough simulator. J. Occup. Environ. Hyg. 11 (8):509–18. doi:10.1080/15459624.2013.877591.
  • Liu, Y., Z. Ning, Y. Chen, M. Guo, Y. Liu, N. K. Gali, L. Sun, Y. Duan, J. Cai, D. Westerdahl, et al. 2020. Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals. Nature 582 (7813):557–60. doi:10.1038/s41586-020-2271-3].
  • Lo, I. L., C. F. Lio, H. H. Cheong, C. I. Lei, T. H. Cheong, X. Zhong, Y. Tian, and N. N. Sin. 2020. Evaluation of SARS-CoV-2 RNA shedding in clinical specimens and clinical characteristics of 10 patients with COVID-19 in Macau. Int. J. Biol. Sci. 16 (10):1698–707. doi:10.7150/ijbs.45357.
  • Lodder, W., and A. M. de Roda Husman. 2020. SARS-CoV-2 in wastewater: Potential health risk, but also data source. Lancet. Gastroenterol. Hepatol. 5 (6):533–4. doi:10.1016/S2468-1253(20)30087-X.
  • Ma, J., X. Qi, H. Chen, X. Li, Z. Zhan, H. Wang, L. Sun, L. Zhang, J. Guo, L. Morawska, et al. 2020. Exhaled breath is a significant source of SARS-CoV-2 emission. MedRxiv (preprint). doi:10.1101/2020.05.31.20115154:2020.05.31.20115154.
  • Mead, K. R., A. Feng, D. C. Hammond, and S. Shulman. 2012. Expedient methods for surge airborne isolation within healthcare settings during response to a natural or manmade epidemic. EPHB 301-05f. NIOSH, 1–184. https://www.cdc.gov/niosh/surveyreports/pdfs/301-05f.pdf.
  • Morawska, L., and D. K. Milton. 2020. It is time to address airborne transmission of COVID-19. Clin. Infect. Dis. doi:10.1093/cid/ciaa939.
  • Napoli, P. E., M. Nioi, E. d’Aloja, and M. Fossarello. 2020. The ocular surface and the coronavirus disease 2019: Does a dual ‘ocular route’ exist? J. Clin. Med. 9(5): 1269. doi:10.3390/jcm9051269.
  • Nardell, E. A. 2016. Indoor environmental control of tuberculosis and other airborne infections. Indoor Air. 26 (1):79–87. doi:10.1111/ina.12232.
  • Ong, S. W. X., Y. K. Tan, P. Y. Chia, T. H. Lee, O. T. Ng, M. S. Y. Wong, and K. Marimuthu. 2020. Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient. JAMA 323 (16):1610. doi:10.1001/jama.2020.3227.
  • OSHA. 2020. Guidance on preparing workplaces for COVID-19. Washington, DC: Occupational Safety and Health Administration: 35.
  • Palatnik, A., and J. J. McIntosh. 2020. Protecting labor and delivery personnel from COVID-19 during the second stage of labor. Am. J. Perinatol. 37(8):854–856. doi:10.1055/s-0040-1709689.
  • Rockx, B., T. Kuiken, S. Herfst, T. Bestebroer, M. M. Lamers, B. B. Oude Munnink, D. de Meulder, G. van Amerongen, J. van den Brand, N. M. A. Okba, et al. 2020. Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model. Science 368:1012–15. doi:10.1126/science.abb7314.
  • Rule, A. M., O. Apau, S. H. Ahrenholz, S. E. Brueck, W. G. Lindsley, M. A. de Perio, J. D. Noti, R. E. Shaffer, R. Rothman, A. Grigorovitch, et al. 2018. Healthcare personnel exposure in an emergency department during influenza season. PLoS One 13 (8):e0203223. doi:10.1371/journal.pone.0203223.
  • Santarpia, J. L., D. N. Rivera, V. Herrera, M. J. Morwitzer, H. Creager, G. W. Santarpia, K. K. Crown, D. Brett-Major, E. Schnaubelt, M. J. Broadhurst, et al. 2020. Transmission potential of SARS-CoV-2 in viral shedding observed at the University of Nebraska Medical Center. MedRxiv (preprint) doi:10.1101/2020.03.23.20039446.
  • Shi, J., Z. Wen, G. Zhong, H. Yang, C. Wang, B. Huang, R. Liu, X. He, L. Shuai, Z. Sun, et al. 2020. Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science 368 (6494):1016–20. doi:10.1126/science.abb7015.
  • Shiu, E. Y. C., N. H. L. Leung, and B. J. Cowling. 2019. Controversy around airborne versus droplet transmission of respiratory viruses: Implication for infection prevention. Curr. Opin. Infect. Dis. 32 (4):372–9. doi:10.1097/QCO.0000000000000563.
  • Sutton, T. C., and K. Subbarao. 2015. Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus. Virology 479-480:247–58. doi:10.1016/j.virol.2015.02.030.
  • Tellier, R., Y. Li, B. J. Cowling, and J. W. Tang. 2019. Recognition of aerosol transmission of infectious agents: A commentary. BMC Infect. Dis. 19 :101. doi:10.1186/s12879-019-3707-y.
  • Thomas, P. R., L. A. Karriker, A. Ramirez, J. Zhang, J. S. Ellingson, K. K. Crawford, J. L. Bates, K. J. Hammen, and D. J. Holtkamp. 2015. Evaluation of time and temperature sufficient to inactivate porcine epidemic diarrhea virus in swine feces on metal surfaces. J. Swine Health Prod. 23:84–90.
  • Tran, K., K. Cimon, M. Severn, C. L. Pessoa-Silva, and J. Conly. 2012. Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: A systematic review. PLoS One 7 (4):e35797. doi:10.1371/journal.pone.0035797.
  • van Doremalen, N., T. Bushmaker, D. H. Morris, M. G. Holbrook, A. Gamble, B. N. Williamson, A. Tamin, J. L. Harcourt, N. J. Thornburg, S. I. Gerber, et al. 2020. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N. Engl. J. Med. 382 (16):1564–7. doi:10.1056/NEJMc2004973.
  • Wan, Y., J. Shang, R. Graham, R. S. Baric, and F. Li. 2020. Receptor recognition by the novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS coronavirus. J. Virol. 94:e00127–20.
  • Wang, W., Y. Xu, R. Gao, R. Lu, K. Han, G. Wu, and W. Tan. 2020. Detection of SARS-CoV-2 in different types of clinical specimens. JAMA. [published online ahead of print, 2020 Mar 11]. doi:10.1001/jama.2020.3786.
  • Weber, D. J., W. A. Rutala, D. J. Anderson, L. F. Chen, E. E. Sickbert-Bennett, and J. M. Boyce. 2016. Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials. Am. J. Infect. Control. 44 (5 Suppl):e77–e84. doi:10.1016/j.ajic.2015.11.015.
  • WHO. 2020. Q&A on coronaviruses (COVID-19). Accsesed May 18, 2020. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/question-and-answers-hub/q-a-detail/q-a-coronaviruses.
  • Wilson, N. M., A. Norton, F. P. Young, and D. W. Collins. 2020. Airborne transmission of severe acute respiratory syndrome coronavirus-2 to healthcare workers: A narrative review. Anaesthesia 75 (8):1086–95. doi:10.1111/anae.15093.
  • Wrapp, D., N. Wang, K. S. Corbett, J. A. Goldsmith, C. L. Hsieh, O. Abiona, B. S. Graham, and J. S. McLellan. 2020. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 367 (6483):1260–3. doi:10.1126/science.abb2507.
  • Xiao, F., J. Sun, Y. Xu, F. Li, X. Huang, H. Li, J. Zhao, J. Huang, and J. Zhao. 2020. Infectious SARS-CoV-2 in feces of patient with severe COVID-19. Emerg. Infect. Dis. 26 (8):1920–2. doi:10.3201/eid2608.200681.
  • Xu, Y., X. Li, B. Zhu, H. Liang, C. Fang, Y. Gong, Q. Guo, X. Sun, D. Zhao, J. Shen, et al. 2020. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat. Med. 26 (4):502–5. doi:10.1038/s41591-020-0817-4.
  • Yu, A. Y., R. Tu, X. Shao, A. Pan, K. Zhou, and J. Huang. 2020a. A comprehensive Chinese experience against SARS-CoV-2 in ophthalmology. Eye Vis. 7:19.
  • Yu, P., F. Qi, Y. Xu, F. Li, P. Liu, J. Liu, L. Bao, W. Deng, H. Gao, Z. Xiang, et al. 2020b. Age-related rhesus macaque models of COVID-19. Animal Model. Exp. Med. 3 (1):93–7. doi:10.1002/ame2.12108.
  • Yuan, L., Q. Tang, T. Cheng, and N. Xia. 2020. Animal models for emerging coronavirus: Progress and new insights. Emerg. Microbes Infect. 9 (1):949–61. doi:10.1080/22221751.2020.1764871.
  • Zhang, T., X. Cui, X. Zhao, J. Wang, J. Zheng, G. Zheng, W. Guo, C. Cai, S. He, and Y. Xu. 2020. Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia. J. Med. Virol. 92:909–914. doi:10.1002/jmv.25795.

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