Advanced search
Publication Cover
Scandinavian Journal of Primary Health Care Volume 38, 2020 - Issue 4
Submit an article Journal homepage
4,016
Views
3
CrossRef citations to date
0
Altmetric
Research Articles

Is C-reactive protein associated with influenza A or B in primary care patients with influenza-like illness? A cross-sectional study

Karin Rystedta Region Västra Götaland, Research and Development Primary Health Care, Research and Development Centre Skaraborg, Skövde, Sweden;b Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;c Centre for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden;d Region Västra Götaland, Närhälsan Södra Ryd Health Care Centre, Skövde, SwedenCorrespondence[email protected]
View further author information
,
Nicolay Jonassen Harbine Department of General Practice, Antibiotic Center for Primary Care, Institute of Health and Society, University of Oslo, Oslo, NorwayView further author information
,
Morten Lindbaeke Department of General Practice, Antibiotic Center for Primary Care, Institute of Health and Society, University of Oslo, Oslo, NorwayView further author information
,
Ruta Radzevicienef Mano Seimos gydytojas, Klaipeda, LithuaniaView further author information
,
Ronny Gunnarssonb Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;c Centre for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden;g Region Västra Götaland, Research and Development Primary Health Care, Research and Development Centre Södra Älvsborg, Borås, SwedenView further author information
,
Robert Eggertsenb Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;h Region Västra Götaland, Research and Development Primary Health Care, Research and Development Centre Göteborg and Södra Bohuslän, Göteborg, SwedenView further author information
,
Christopher C. Butleri Department of Primary Care Health Services, University of Oxford, Radcliffe Observatory Quarter, Oxford, UKView further author information
,
Alike W. van der Veldenj Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The NetherlandsView further author information
,
Theo J. Verheijj Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The NetherlandsView further author information
&
Pär-Daniel Sundvallb Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden;c Centre for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden;g Region Västra Götaland, Research and Development Primary Health Care, Research and Development Centre Södra Älvsborg, Borås, SwedenView further author information
 show all
Pages 447-453 | Received 11 Jun 2020, Accepted 23 Sep 2020, Published online: 11 Nov 2020

References

  • Fitzner J, Qasmieh S, Mounts AW, et al. Revision of clinical case definitions: influenza-like illness and severe acute respiratory infection. Bull World Health Organ. 2018;96(2):122–128.
  • Cassini A, Colzani E, Pini A, et al. Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the burden of communicable diseases in Europe study, European Union and European economic area countries, 2009 to 2013. Euro Surveill. 2018;23(16):17-00454.
  • Call SA, Vollenweider MA, Hornung CA, et al. Does this patient have influenza? JAMA. 2005;293(8):987–997.
  • Saust LT, Bjerrum L, Siersma V, et al. Quality assessment in general practice: diagnosis and antibiotic treatment of acute respiratory tract infections. Scand J Prim Health Care. 2018;36(4):372–379.
  • Rebnord IK, Sandvik H, Hunskaar S. Use of laboratory tests in out-of-hours services in Norway. Scand J Prim Health Care. 2012;30(2):76–80.
  • Lemiengre MB, Verbakel JY, Colman R, et al. Point-of-care CRP matters: normal CRP levels reduce immediate antibiotic prescribing for acutely ill children in primary care: a cluster randomized controlled trial. Scand J Prim Health Care. 2018;36(4):423–436.
  • Pepys MB, Hirschfield GM. C-reactive protein: a critical update. J Clin Invest. 2003;111(12):1805–1812.
  • Verbakel JY, Lee JJ, Goyder C, et al. Impact of point-of-care C reactive protein in ambulatory care: a systematic review and meta-analysis. BMJ Open. 2019;9(1):e025036.
  • Melbye H, Hvidsten D, Holm A, et al. The course of C-reactive protein response in untreated upper respiratory tract infection. Br J Gen Pract. 2004;54(506):653–658.
  • Whicher JT, Chambers RE, Higginson J, et al. Acute phase response of serum amyloid A protein and C reactive protein to the common cold and influenza. J Clin Pathol. 1985;38(3):312–316.
  • Haran JP, Suner S, Gardiner F. Correlation of C-reactive protein to severity of symptoms in acute influenza A infection. J Emerg Trauma Shock. 2012;5(2):149–152.
  • Zimmerman O, Rogowski O, Aviram G, et al. C-reactive protein serum levels as an early predictor of outcome in patients with pandemic H1N1 influenza A virus infection. BMC Infect Dis. 2010;10(1):288.
  • Tekin S, Keske S, Alan S, et al. Predictors of fatality in influenza A virus subtype infections among inpatients in the 2015-2016 season. Int J Infect Dis. 2019;81:6–9.
  • Wu W, Shi D, Fang D, et al. A new perspective on C-reactive protein in H7N9 infections. Int J Infect Dis. 2016;44:31–36.
  • Cinemre H, Karacer C, Yucel M, et al. Viral etiology in adult influenza-like illness/acute respiratory infection and predictivity of C-reactive protein. J Infect Dev Ctries. 2016;10(7):741–746.
  • Flick H, Drescher M, Prattes J, et al. Predictors of H1N1 influenza in the emergency department: proposition for a modified H1N1 case definition. Clin Microbiol Infect. 2014;20(2):O105–8.
  • Butler CC, van der Velden AW, Bongard E, et al. Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial. Lancet. 2020;395(10217):42–52.
  • Vigushin DM, Pepys MB, Hawkins PN. Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest. 1993;91(4):1351–1357.
  • Koutsakos M, Nguyen TH, Barclay WS, et al. Knowns and unknowns of influenza B viruses. Future Microbiol. 2016;11(1):119–135.
  • Yoon JW, Choi DY, Lee SH, et al. Analysis of clinical manifestations and laboratory findings in children with influenza B-associated myositis: a single center study. Korean J Fam Med. 2018;39(1):37–41.
  • Lalueza A, Folgueira D, Munoz-Gallego I, et al. Influence of viral load in the outcome of hospitalized patients with influenza virus infection. Eur J Clin Microbiol Infect Dis. 2019;38(4):667–673.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.