Insulin initiation in patients with type 2 diabetes is often delayed, but access to a diabetes nurse may help—insights from Norwegian general practice

References

• Guthrie B, Inkster M, Fahey T. Tackling therapeutic inertia: role of treatment data in quality indicators. BMJ. 2007;335(7619):542–544. doi: 10.1136/bmj.39259.400069.AD.
   PubMedGoogle Scholar
• Lavoie KL, Rash JA, Campbell TS. Changing provider behavior in the context of chronic disease management: focus on clinical inertia. Annu Rev Pharmacol Toxicol. 2017;57(1):263–283. doi: 10.1146/annurev-pharmtox-010716-104952.
   PubMedGoogle Scholar
• Khunti KA, Gomes MB, Pocock S, et al. Therapeutic inertia in the treatment of hyperglycaemia in patients with type 2 diabetes: a systematic review. Diabetes Obes Metab. 2018;20(2):427–437. doi: 10.1111/dom.13088.
   PubMed Web of Science ®Google Scholar
• Khunti KA, Cigrovski B-ç, Ludvik B, et al. Regional variations in definitions and rates of hypoglycaemia: findings from the global HAT observational study of 27 585 people with type 1 and insulin-treated type 2 diabetes mellitus. Diabet Med. 2018;35(9):1232–1241. doi: 10.1111/dme.13662.
   PubMed Web of Science ®Google Scholar
• Aleppo G, Beck RA, Bailey R, et al. The effect of discontinuing continuous glucose monitoring in adults With type 2 diabetes treated With basal insulin. Diabetes Care. 2021;44(12):2729–2737. doi: 10.2337/dc21-1304.
   PubMedGoogle Scholar
• Khunti K, Wolden ML, Thorsted BL, Comment on Khunti. Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000 people. Diabetes Care. 2013;36(11):3411–3417. doi: 10.2337/dc13-0331.
   PubMed Web of Science ®Google Scholar
• Hayes RP, Fitzgerald JF, Jacober SJ. Primary care physician beliefs about insulin initiation in patients with type 2 diabetes. Int J Clin Pract. 2008;62(6):860–868. doi: 10.1111/j.1742-1241.2008.01742.x.
   PubMed Web of Science ®Google Scholar
• Khunti K, Millar-Jones D. Clinical inertia to insulin initiation and intensification in the UK: a focused literature review. Prim Care Diabetes. 2017;11(1):3–12. doi: 10.1016/j.pcd.2016.09.003.
   PubMed Web of Science ®Google Scholar
• Shaefer CF, Anderson J. The importance of postprandial glycemic control: optimizing add-on therapy to basal insulin. Postgrad Med. 2016;128(1):137–144. doi: 10.1080/00325481.2016.1103640.
   PubMed Web of Science ®Google Scholar
• Escalada J, Orozco-Beltran D, Morillas C, et al. Attitudes towards insulin initiation in type 2 diabetes patients among healthcare providers: a survey research. Diabetes Res Clin Pract. 2016;122:46–53. doi: 10.1016/j.diabres.2016.10.003.
   PubMed Web of Science ®Google Scholar
• Peyrot M, Rubin RR, Lauritzen T, et al. Resistance to insulin therapy Among patients and providers: results of the cross-national diabetes attitudes, wishes, and needs (DAWN) study. Diabetes Care. 2005;28(11):2673–2679. doi: 10.2337/diacare.28.11.2673.
   PubMed Web of Science ®Google Scholar
• Perreault L, Vincent L, Neumiller JJ, et al. Initiation and titration of basal insulin in primary care: barriers and practical solutions. J Am Board Fam Med. 2019;32(3):431–447. doi: 10.3122/jabfm.2019.03.180162.
   PubMed Web of Science ®Google Scholar
• Peyrot M, Barnett AF, Meneghini LFF-S-D, et al. Insulin adherence behaviours and barriers in the multinational global attitudes of patients and physicians in insulin therapy study. Diabet Med. 2012;29(5):682–689. doi: 10.1111/j.1464-5491.2012.03605.x.
   PubMed Web of Science ®Google Scholar
• (Helsedirektoratet) NDoH. Nasjonal faglig retningslinje for behandling av diabetes. www.helsedirektoratet.no/diabetes. 2018.
   Google Scholar
• Semlitsch T, Engler J, Siebenhofer A, et al. (Ultra-)long-acting insulin analogues versus NPH insulin (human isophane insulin) for adults with type 2 diabetes mellitus. Cochrane Database Syst Rev. 2020;11(11):CD005613. doi: 10.1002/14651858.CD005613.pub4.
   PubMedGoogle Scholar
• Davis CS, Fleming JW, Fau- Malinowski S, et al. Ultra-long-acting insulins: a review of efficacy, safety, and implications for practice. J Am Assoc Nurse Pract. 2018;30(7):373–380. doi: 10.1097/JXX.0000000000000076.
   PubMed Web of Science ®Google Scholar
• Jenssen TG, Kristensen B, Uglenes I, et al. Primary healthcare teams with a diabetes nurse is a solution. Tidsskr Nor Legeforen 1903.
   Google Scholar
• Bakke Å, Cooper JG, Thue G, et al. Type 2 diabetes in general practice in Norway 2005-2014: moderate improvements in risk factor control but still major gaps in complication screening. BMJ Open Diabetes Res Care. 2017;5(1):e000459. doi: 10.1136/bmjdrc-2017-000459.
   PubMed Web of Science ®Google Scholar
• Bakke Å, Tran AT, Dalen I, et al. Population, general practitioner and practice characteristics are associated with screening procedures for microvascular complications in type 2 diabetes care in Norway. Diabet Med. 2019;36(11):1431–1443. doi: 10.1111/dme.13842.
   PubMed Web of Science ®Google Scholar
• Pope GC, Burge RT. Economies of scale in physician practice. Med Care Res Rev. 1996;53(4):417–440. doi: 10.1177/107755879605300403.
   PubMed Web of Science ®Google Scholar
• Dale J, Martin S, Fau- Gadsby R, et al. Insulin initiation in primary care for patients with type 2 diabetes: 3-year follow-up study. (1878–0210). Electronic.
   Google Scholar
• Sandvik H, Hetlevik Ø, Blinkenberg J, et al. Continuity in general practice as predictor of mortality, acute hospitalisation, and use of out-of-hours care: a registry-based observational study in Norway. Br J Gen Pract. 2022;72(715):e84–e90. doi: 10.3399/BJGP.2021.0340.
   PubMed Web of Science ®Google Scholar
• Thomsen RA, Baggesen LM, Søgaard M, et al. Effectiveness of intensification therapies in danes with type 2 diabetes who use basal insulin: a population-based study. Diabet Med. 2017;34(2):213–222. doi: 10.1111/dme.13168.
   PubMed Web of Science ®Google Scholar
• Furler J, Ο’Neal D, Speight J, et al. Supporting insulin initiation in type 2 diabetes in primary care: results of the stepping Up pragmatic cluster randomised controlled clinical trial. BMJ. 2017;356:j783. doi: 10.1136/bmj.j783.
   PubMedGoogle Scholar
• Slåtsve KB, Claudi T, Lappegård KT, et al. Actors associated with treatment in primary versus specialist care: a population-based study of people with type 2 and type 1 diabetes [published correction appears. Diabet Med. 2021;38(7):e14580. in Diabet Med. 2022 Sep; 39(9):e14915]. Diabet Med doi: 10.1111/dme.14580.
   PubMed Web of Science ®Google Scholar