Treatment and outcome of recurrent osteosarcoma: Experience at Rizzoli in 235 patients initially treated with neoadjuvant chemotherapy

References

• Fuchs N, Bielack SS, Epler D, et al. Long-term results of the co-operative German-Austrian-Swiss osteosarcoma study group's protocol COSS-86 of intensive multidrug chemotherapy and surgery for osteosarcoma of the limbs. Ann Oncol 1998; 9: 893–9
   PubMed Web of Science ®Google Scholar
• Bacci G, Ferrari S, Bertoni F, et al. Long-term outcome for patients with nonmetastatic osteosarcoma of the extremity treated at Istituto Ortopedico Rizzoli according to the IOR/OS-2 protocol: an updated report. J Clin Oncol 2000; 18: 4016–27
   PubMed Web of Science ®Google Scholar
• Goorin AM, Schwartzentruber DJ, Devidas M, et al. Presurgical chemotherapy compared with immediate surgery and adjuvant chemotherapy for nonmetastatic osteosarcoma: Pediatric Oncology Group Study POG-8651. J Clin Oncol 2003; 21: 1574–80
   PubMed Web of Science ®Google Scholar
• Smeland S, Muller C, Alvegard T, et al. Scandinavian Sarcoma Group Osteosarcoma Study SSG VIII: prognostic factors for outcome and the role of replacement salvage chemotherapy for poor histological responders. Eur J Cancer 2003; 39: 488–94
   PubMed Web of Science ®Google Scholar
• Martini N, Huvos AG, Mike V, Marcove RC, Beattie EJ. Multiple pulmonary resection for metastatic osteogenic sarcoma. J Bone Joint Surg (Am) 1971; 12: 271–80
   Google Scholar
• Hawkins DS, Arndt CA. Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy. Cancer 2003; 98: 2447–56
   PubMed Web of Science ®Google Scholar
• Antunes M, Bernardo J, Salete M, Prieto D, Eugenio L, Tavares P. Excision of pulmonary metastases of osteogenic sarcoma of the limb. Eur J Cardiothorac Surg 1999; 15: 592–6
   PubMed Web of Science ®Google Scholar
• Picci P, Ruggieri P, Mercuri M, et al. Primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) for osteosarcoma of the extremities. The Istituto Rizzoli experience in 127 patients treated peroperatively with intravenous methotrexate (high versus moderate doses) and intraarterial cisplatin. Cancer 1990; 65: 2539–53
   PubMed Web of Science ®Google Scholar
• Bacci G, Picci P, Ferrari S, et al. Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin. Cancer 1993; 72: 3227–38
   PubMed Web of Science ®Google Scholar
• Ferrari S, Mercuri M, Picci P, et al. Nonmetastatic osteosarcoma of the extremity: results of a neoadjuvant chemotherapy protocol (IOR/OS-3) with high-dose methotrexate, intraarterial or intravenous cisplatin, doxorubicin, and salvage chemotherapy based on histologic response. Tumori 1999; 85: 458–64
   PubMed Web of Science ®Google Scholar
• Bacci G, Briccoli A, Ferrari S, et al. Neoadjuvant chemotherapy for osteosarcoma of the extremity: long-term results of the Rizzoli's 4th protocol. Eur J Cancer 2001; 37: 2030–9
   PubMed Web of Science ®Google Scholar
• Bacci G, Ferrari S, Longhi A, et al. High-dose ifosfamide in combination with high-dose methotrexate, doxorubicin and cisplatin in the neoadjuvant treatment of extremity osteosarcoma: preliminary results of an Italian Sarcoma Group/Scandinavian Sarcoma Group pilot study. J Chemother 2002; 14: 198–206
   PubMed Web of Science ®Google Scholar
• Picci P, Bacci G, Campanacci M, et al. Histologic evaluation of necrosis in osteosarcoma induced by chemotherapy. Cancer 1985; 56: 1515–21
   PubMed Web of Science ®Google Scholar
• Spanos PK, Payne WS, Ivins JC, Pritchard DJ. Pulmonary resection for metastatic osteogenic sarcoma. J Bone Joint Surg (Am) 1976; 58: 624–8
   PubMed Web of Science ®Google Scholar
• Heij HA, Vos A, de Kraker J, Voute PA. Prognostic factors in surgery for pulmonary metastases in children. Surgery 1994; 115: 687–93
   PubMed Web of Science ®Google Scholar
• Schaller RT, Haas J, Schaller J, Morgan A, Bleyer A. Improved survival in children with osteosarcoma following resection of pulmonary metastases. J Pediatr Surg 1982; 17: 546–50
   PubMed Web of Science ®Google Scholar
• Pastorino U, Gasparini M, Tavecchio L, et al. The contribution of salvage surgery to the management of childhood osteosarcoma. J Clin Oncol 1991; 9: 1357–62
   PubMed Web of Science ®Google Scholar
• Ward WG, Mikaelian K, Dorey F, et al. Pulmonary metastases of stage IIB extremity osteosarcoma and subsequent pulmonary metastases. J Clin Oncol 1994; 12: 1849–58
   PubMed Web of Science ®Google Scholar
• Saeter G, Hoie J, Stenwig AE, Johansson AK, Hannisdal E, Solheim O. Systemic relapse of patients with osteogenic sarcoma: prognostic factors in long term survival. Cancer 1995; 75: 1084–93
   PubMed Web of Science ®Google Scholar
• Temek BK, Wexler LH, Steinberg SM, McClure LL, Horowitz M, Pass HI. Metastasectomy for sarcomatous pediatric histologies: results and prognostic factors. Ann Thorac Surg 1995; 59: 1385–90
   PubMed Web of Science ®Google Scholar
• Goorin AM, Shuster JJ, Baker A, Horowitz ME, Meyer WH, Link MP. Changing patterns of pulmonary metastases with adjuvant chemotherapy in patients with osteosarcoma: results from the Multiinstitutional Osteosarcoma Study. J Clin Oncol 1991; 9: 600–5
   PubMed Web of Science ®Google Scholar
• Tabone MD, Kalifa C, Rodary C, Raquin M, Valteau-Couranet D, Lemerle J. Osteosarcoma recurrences in pediatric patients previously treated with intensive chemotherapy. J Clin Oncol 1994; 12: 2614–20
   PubMed Web of Science ®Google Scholar
• Huth JF, Eilber FR. Patterns of recurrence after resection of osteosarcoma of the extremity: strategies for treatment of metastases. Arch Surg 1989; 124: 122–6
   PubMedGoogle Scholar
• Jaffe N, Smith E, Abelson HT, Frei E. Osteogenic sarcoma: alterations in the pattern of pulmonary metastases with adjuvant chemotherapy. J Clin Oncol 1983; 1: 251–4
   PubMed Web of Science ®Google Scholar
• Bacci G, Ferrari S, Longhi A, et al. Pattern of relapse in patients with osteosarcoma of the extremities treated with neoadjuvant chemotherapy. Eur J Cancer 2001; 37: 32–8
   PubMed Web of Science ®Google Scholar
• Kempf-Bielack B, Bielack SS, Jurgens H, et al. Osteosarcoma relapse after combined modality therapy: and analysis of unselected patients in the Cooperative Osteosarcoma Study Group. J Clin Oncol 2005; 23: 559–68
   PubMed Web of Science ®Google Scholar