Synergistic antitumor activity of XIAP-shRNA and TRAIL expressed by oncolytic adenoviruses in experimental HCC

References

• Scherer L, Rossi JJ. RNAi applications in mammalian cells. Biotechniques 2004; 36: 557–61
   PubMed Web of Science ®Google Scholar
• Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001; 15: 188–200
   PubMed Web of Science ®Google Scholar
• Kim DH, Behlke MA, Rose SD, Chang MS, Choi S, Rossi JJ. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat Biotechnol 2004; 22: 321–5
   PubMed Web of Science ®Google Scholar
• Donze O, Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res 2002; 30: e46
   PubMed Web of Science ®Google Scholar
• Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296: 550–3
   PubMed Web of Science ®Google Scholar
• Sui G, Soohoo C, Affar el B, Gay F, Shi Y, Forrester Wc, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 5515–20
   PubMed Web of Science ®Google Scholar
• Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003; 33: 401–6
   PubMed Web of Science ®Google Scholar
• Hommel JD, Sears RM, Georgescu D, Simmons DL, DiLeone RJ. Local gene knockdown in the brain using viral-mediated RNA interference. Nat Med 2003; 9: 1539–44
   PubMed Web of Science ®Google Scholar
• Nicholson LJ, Philippe M, Paine AJ, Mann DA, Dolphin CT. RNA interference mediated in human primary cells via recombinant baculoviral vectors. Mol Ther 2005; 11: 638–44
   PubMed Web of Science ®Google Scholar
• Carette JE, Overmeer RM, Schagen FH, Alemany R, Barski OA, Gerritsen WR, et al. Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells. Cancer Res 2004; 64: 2663–7
   PubMed Web of Science ®Google Scholar
• Zhang YA, Nemunaitis J, Samuel SK, Chen P, Shen Y, Tong AW. Antitumor activity of an oncolytic adenovirus-delivered oncogene small interfering RNA. Cancer Res 2006; 66: 9736–43
   PubMed Web of Science ®Google Scholar
• Wilkinson JC, Cepero E, Boise LH, Duckett CS. Upstream regulatory role for XIAP in receptor-mediated apoptosis. Mol Cell Biol 2004; 24: 7003–14
   PubMedGoogle Scholar
• Pei Z, Chu L, Zou W, Zhang Z, Qiu S, Qi R, et al. An oncolytic adenoviral vector of Smac increases antitumor activity of TRAIL against HCC in human cells and in mice. Hepatology 2004; 39: 1371–81
   PubMed Web of Science ®Google Scholar
• Zhao H, Xu Y. Mad-overexpression down regulates the maliganant growth and p53 mediated apoptosis in human hepatocellular carcinoma BEL7404 cells. Cell Res 1999; 9: 51–9
   Google Scholar
• Zhang ZL, Zou WG, Luo CX, Li BH, Wang JH, Sun LY, et al. An armed oncolytic adenovirus system, ZD55-gene, demonstrating potent antitumoral efficacy. Cell Res 2003; 13: 481–9
   PubMed Web of Science ®Google Scholar
• Liu XY, Qiu SB, Zou WG, Pei ZF, Gu JF, Luo CX, et al. Effective gene-virotherapy for complete eradication of tumor mediated by the combination of hTRAIL (TNFSF10) and plasminogen k5. Mol Ther 2005; 11: 531–41
   Google Scholar
• Chawla-Sarkar M, Leaman DW, Jacobs BS, Boden EC. IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis. J Immunol 2002; 169: 847–55
   Google Scholar
• Dong ZX, Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis inducing ligand (TRAIL) receptor and Flice inhibitory protein expression to TRAIL induced apoptosis of melanoma cells. Cancer Res 1999; 59: 2747–53
   Google Scholar
• Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. Tumor necrosis factor related apoptosis inducing ligand induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res 2001; 61: 7339–48
   PubMed Web of Science ®Google Scholar
• Bridge AJ, Pebernard S, Ducraux A, Nicoulaz AL, Iggo R. Induction of an interferon response by RNAi vectors in mammalian cells. Nat Genet 2003; 34: 263–4
   PubMed Web of Science ®Google Scholar
• Sioud M, Sorensen DR. Cationic liposome-mediated delivery of siRNAs in adult mice. Biochem Biophys Res Commun 2003; 312: 1220–5
   PubMed Web of Science ®Google Scholar
• Vrolijk JM, Kaul A, Hansen BE, Lohmann V, Haagmans BL, Schalm SW, et al. A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C. J Virol Methods 2003; 110: 201–9
   PubMed Web of Science ®Google Scholar
• Bischoff JR, Kirn DH, Williams A, Heise C, Horn S, Muna M, et al. An adenovirus mutant that replicates selectively in p53-deficient human tumour cells. Science 1996; 274: 373–6
   PubMed Web of Science ®Google Scholar
• Wildner O, Blaese RM, Morris JC. Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase. Cancer Res 1999; 59: 410–3
   PubMed Web of Science ®Google Scholar
• Ries SJ, Brandts CH, Chung AS, Biederer CH, Hann BC, Lipner EM, et al. Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl 1520 (ONYX-015). Nat Med 2000; 6: 1128–33
   PubMed Web of Science ®Google Scholar
• O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A, et al. Late viral RNA export, rather than p53 inactivation, determines ONXY-015 tumor selectivity. Cancer cell 2004; 6: 611–23
   PubMed Web of Science ®Google Scholar
• Goodrum FD, Ornelles DA. p53 status does not determine outcome of E1B 55 kilo-dalton mutant adenovirus lytic infection. J Virol 1998; 72: 9479–90
   PubMed Web of Science ®Google Scholar
• Turnell A, Grand R, Gallimore P. The replicative capacities of large E1B-null group A and group C adenovirus are independent of host cell p53 status. J Virol 1999; 73: 2074–83
   PubMed Web of Science ®Google Scholar
• Nemunaitis J, Khuri F, Ganly I, Arseneau J, Posner M, Vokes E, et al. Phase II trial of intratumoral administration of ONYX-015, a replication selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 2001; 19: 289–98
   PubMed Web of Science ®Google Scholar
• Zhao L, Gu J, Dong A, Zhang Y, Zhong L, He L, et al. Potent antitumor activity of oncolytic adenovirus expressing mda-7/IL-24 for colorectal cancer. Hum Gene Ther 2005; 16: 845–58
   PubMed Web of Science ®Google Scholar
• Kirn D. Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?. Gene Ther 2001; 8: 89–98
   PubMed Web of Science ®Google Scholar
• Kirn D. Oncolytic virotherapy for cancer with the adenovirus dl1520 (Onyx-015): Results of phase I and II trials. Expert Opin Biol Ther 2001; 1: 525–38
   PubMed Web of Science ®Google Scholar
• Holcik M, Gibson H, Korneluk RG. XIAP: Apoptotic brake and promising therapeutic target. Apoptosis 2001; 6: 253–61
   PubMed Web of Science ®Google Scholar
• Salvesen GS, Duckett CS. IAP proteins: Blocking the road to death's door. Nat Rev Mol Cell Biol 2002; 3: 401–10
   PubMed Web of Science ®Google Scholar
• Xu D, Bureau Y, McIntyre DC, Nicholson DW, Liston P, Zhu Y, et al. Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus. J Neurosci 1999; 19: 5026–33
   PubMed Web of Science ®Google Scholar
• Kugler S, Straten G, Kreppel F, Isenmann S, Liston P, Bahr M. The X-linked inhibitor of apoptosis (XIAP) prevents cell death in axotomized CNS neurons in vivo. Cell Death Differ 2000; 7: 815–24
   PubMed Web of Science ®Google Scholar
• Perrelet D, Ferri A, Liston P, Muzzin P, Korneluk RG, Kato AC. IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo. Nat Cell Biol 2002; 4: 175–9
   PubMed Web of Science ®Google Scholar
• Ng CP, Bonavida B. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: Sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Mol Cancer Ther 2002; 1: 1051–8
   PubMed Web of Science ®Google Scholar
• White E. Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus. Oncogene 2001; 20: 7836–46
   PubMed Web of Science ®Google Scholar
• Andersson MG, Haasnoot PC, Xu N, Berenjian S, Berkhout B, Akusjarvi G. Suppression of RNA interference by adenovirus virus-associated RNA. J Virol 2005; 79: 9556–65
   PubMed Web of Science ®Google Scholar