Aspects on the Development of Radiation Therapy and Radiation Biology Since the Early Work of Rolf Wideröe

References

• Zuppinger A, Poretti G, eds. Proceedings of the Symposium on High-Energy Electrons, Montreux, Switzerland 7th to 11th September 1964. Springer Verlag, 1965.
   Google Scholar
• Laughlin A, ed. High-energy radiation therapy dosimetry. Ann. N York Acad Sci 1969; 161: 1–370.
   Google Scholar
• Wider& R. Collimator for beams of high-velocity electrons, US patent 3.227.880, 1966.
   Google Scholar
• Lax I, Brahme A. On the collimation of high energy electron beams. Acta Radiol Oncol 1980; 19: 199–207.
   PubMed Web of Science ®Google Scholar
• Brahme A. Design principles, beam properties and clinical possibilities of a new generation of radiation therapy equip-ment. Acta Oncol 1987; 26: 403–12.
   PubMed Web of Science ®Google Scholar
• Svensson R, Brahme A. Effective source size, yield and beam profile from multi-layered bremsstrahlung targets. Phys Med Biol 1996; 41: 1353–79.
   PubMed Web of Science ®Google Scholar
• Schinz HR, Wider& R. Die 31-MeV-Betatronanlage der Ra-diotherapeutischen Klinik im Kantonsspital Zurich. Acta Ra-diol 1952; 37: 374–87.
   PubMed Web of Science ®Google Scholar
• Brahme A. Optimization of stationary and moving beam radiation therapy techniques. Radiother Oncol 1988; 12: 129–40.
   PubMed Web of Science ®Google Scholar
• Wider& R. High-energy electron therapy and the two-com-ponent theory of radiation. Acta Radiol 1966; 4: 257–78.
   Google Scholar
• Wider& R. Quantitative and qualitative aspects of radiobiol-ogy and their significance in radiation therapy. Acta Radiol 1971; 10: 605–24.
   Google Scholar
• Ward JF. Biochemistry of DNA lesions. Radiat Res 1985; 104: 103–11.
   Google Scholar
• Brahme A, Rydberg B, Blomquist P. Dual spatially correlated nucleosomal double strand breaks in cell inactivation. In: Goodhead DT, O'Neill P, Menzel HG, eds. Microdosimetry: an interdisciplinary approach. Cambridge: The Royal Society of Chemistry, 1997.
   Google Scholar
• Joiner M. Induced radioresistance: an overview and historical perspective. Int J Radiat Biol 1994; 65: 79–84.
   PubMedGoogle Scholar
• Lax I, Brahme A. Rotation therapy using a novel high-gradi-ent filter. Radiology 1982; 145: 473–8.
   PubMedGoogle Scholar
• Bortfeld T, Biirkelbach J, Boesecke R, Schlegel W. Methods of image reconstruction from projections applied to confor-mation radiotherapy. Phys Med Biol 1990; 35: 1423–34.
   PubMed Web of Science ®Google Scholar
• Holmes T, Mackie RT, Simpkin D, Reckwerdt P. A unified approach to the optimization of brachytherapy and external beam dosimetry. Int J Radiat Oncol Biol Phys 1991; 20: 859–73.
   PubMedGoogle Scholar
• Brahme A. Treatment optimization using physical and radio-biological objective functions. In: Smith AR, ed. Radiation therapy physics. Berlin: Springer, 1995: 209–46.
   Google Scholar
• Brahme A. Biological and physical dose optimization in radi-ation therapy. In: Fortner JC, Rhoads JE, eds. Accomplish-ments in cancer research 1991. General Motors Cancer Research Foundation, 1992: 265–98.
   Google Scholar
• Brahme A, Ágren A-K. Optimal dose distribution for eradica-tion of heterogeneous tumours. Acta Oncol 1987; 26: 377–85.
   PubMed Web of Science ®Google Scholar
• Källman P, Lind BK, Brahme A. An algorithm for maximiz-ing the probability of complication free tumor control in radiation therapy. Phys Med Biol 1992; 37: 871–90.
   Google Scholar
• Brahme A, Lind B, Källman P. Inverse radiation therapy planning as a tool for 3D dose optimization. Physica Medica 1990; 6: 53–63.
   Google Scholar
• Söderström S, Gustafsson A, Brahme A. The clinical value of different treatment objectives and degrees of freedom in radi-ation therapy optimization. Radiother Oncol 1993; 29: 148–63.
   Google Scholar
• Gustafsson A, Svensson R, Lind BK, Brahme A. Simulta-neous optimization of dynamic multileaf collimation and scanning patterns or compensation filters using a generalized pencil beam algorithm. Med Phys 1995; 22: 1141–56.
   PubMed Web of Science ®Google Scholar
• Söderström S, Gustafsson A, Brahme A. Few field radiation therapy optimization in the phase space of complication free tumor control. Int J Imag Syst Technol 1995; 6: 91–103.
   Google Scholar
• Källman P, Lind BK, Eklöf A, Brahme A. Shaping of arbi-trary dose distributions by dynamic multileaf collimation. Phys Med Biol 1988; 33: 1291–300.
   Google Scholar
• Miller DW. Optimization of attenuator shapes for multiple field radiation treatment. In Paliwal BR, Herbert DE, Orton CG, eds. Optimization of cancer radiotherapy. New York: AAPM, Symp Proc No. 5, Am Inst Physics, 1985.
   Google Scholar
• Ulso N, Brahme A. Computer-aided irradiation technique optimization. In: Zink S, ed. Proc. Joint US-Scandinavian Symp on further directions of computer aided radiation ther-apy. San Antonio, Texas: National Cancer Institute Bethesda, MD, 1988.
   Google Scholar
• Brahme A. Optimization of radiation therapy and the devel-opment of multileaf collimation. Int J Radiat Oncol Biol Phys 1993; 25: 373–5.
   PubMedGoogle Scholar
• Källman P, Ágren A-K, Brahme A. Tumour and normal tissue responses to fractionated non-uniform dose delivery. Int J Radiat Biol 1992; 62: 249–62.
   PubMed Web of Science ®Google Scholar
• kgren Cronqvist A-K. Quantification of the response of heterogeneous tumours and organized normal tissues to frac-tionated radiotherapy. Thesis, Stockholm University, 1995.
   Google Scholar
• Kijewski PK, Chin LM, Bjärngard BE. Wedge-shaped dose distributions by computer-controlled collimator motion. Med Phys 1978; 5: 426–9.
   Google Scholar
• Carol MP. An automatic 3D treatment planning and imple-mentation system for optimised conformal therapy by the NOMOS Corporation. Proc 34th Ann Meeting of the Ameri-can Society for Therapeutic Radiology and Oncology, 1992, and Int J Imag Syst Technol 1995; 6: 56–61.
   Google Scholar
• Mackie TR, Holmes TW, Reckwerdt PJ, Yang J. Tomother-apy: optimized planning and delivery of radiation therapy. Int J Imag Syst Technol 1995; 6: 43–55.
   Google Scholar
• Carpender JWJ, et al. Radiation therapy with high-energy electrons using pencil beam scanning. Am J Roentgenology 1963; 90: 221–30.
   Google Scholar
• LW' J, Lind BK, Brahme A. A general code for dynamic and stochastic optimization of radiotherapeutic treatment plans. Med Biol Engin Comp 1997; 35: 920.
   Google Scholar
• Gustafsson A, Lind BK, Brahme A. A generalized pencil beam algorithm for optimization of radiation therapy. Med Phys 1994; 21: 343–56.
   Google Scholar
• Karlsson M, Nystrom H, Svensson H. Electron beam charac-teristics of the 50 MeV racetrack microtron. Med Phys 1992; 19: 307–15.
   Google Scholar
• Lind B, Brahme A. Development of treatment techniques for radiotherapy optimization. Int J Imag Syst Technol 1995; 6: 33–42.
   Web of Science ®Google Scholar
• Brahme A, Källman P, Tilikidis A. Developments in ion beam therapy planning and treatment optimization. In: Linz U, ed. Ion beams in tumor therapy. London: Chapman & Hall, 1995: 290–9.
   Google Scholar
• LW' J, Lind BK, Brahme A. An adaptive feedback algorithm for robust dose delivery in fractionated radiotherapy. XIIth ICCR, Salt Lake City, USA, 1997: p 227–30.
   Google Scholar
• Svensson R. Development of a compact high energy treat-ment unit combining narrow pencil beam scanning and multileaf collimation. (Dissertation). Stockholm University, 1998.
   Google Scholar