Benefits of Accelerated Hyperfractionation for Head and Neck Cancer

REFERENCES

• Withers HR, McBride WH. Biologic basis of radiation ther-apy. In: Perez CA, Brady LW, ed. Principles and practice of radiation oncology. Third edition. Philadelphia: Lipincott—Raven, 1997: 79–118.
   Google Scholar
• Ang KK, Thames HD, Peters U. Altered fractionation sched-ules. In: Perez CA, Brady LW, eds. Principles and practice of radiation oncology, Third edition. Philadelphia: Lipincott-Raven, 1997: 119–42.
   Google Scholar
• Harwood AR, Keane TJ. General principles of irradiation therapy as applied to head and neck cancer. J Otolaryngol 1982; 11: 69–76.
   PubMedGoogle Scholar
• Dose specification for reporting external beam therapy with photons and electrons. Report 29: International Commission on Radiation Units and Measurements (ICRU). Washington, USA, 1978.
   Google Scholar
• Withers HR, Peters LJ, Taylor JM, et al. Local control of carcinoma of the tonsil by radiation therapy: an analysis of patterns of fractionation in nine institutions. Int .1- Radiat Oncol Biol Phys 1995; 33: 549–62.
   PubMed Web of Science ®Google Scholar
• International Union Against Cancer (UICC). TNM Classifica-tion of Malignant Tumors. 4th ed., Geneve: UICC, 1987.
   Google Scholar
• Fowler JF. JF Kirk Memorial Lecture: What next in fraction-ated radiotherapy? Br J Cancer 1984; 49 (Suppl 6): 285S–300S.
   Google Scholar
• Withers HR. Biologic basis for altered fractionation schemes. Cancer 1985; 55: 2086–95.
   PubMedGoogle Scholar
• Horiot JC, Chaplain G, van der Schueren E, Gonzalez Gonza-lez D, van den Bogaert W, van Limbergen E. A phase III study of accelerated fractionation in the radiotherapy of advanced head and neck carcinoma. EORTC Cooperative Group of Radiotherapy Protocol 22851, EORTC Data Center Brussels, 1985.
   Google Scholar
• Million RR, Parsons JT, Cassisi NJ. Twice-a-day irradiation technique for squamous cell carcinomas of the head and neck. Cancer 1985; 55: 2096–9.
   Google Scholar
• Wang CC, Blitzer PH, Suit HD. Twice-a-day radiation therapy for cancer of the head and neck. Cancer 1985; 55: 2100–4.
   Google Scholar
• Cummings BJ, Keane TJ, Pintille M, et al. A prospective randomized trial of hyperfractionated versus conventional once daily radiation for advanced squamous cell carcinomas of the larynx and pharynx (abstract). Radiother Oncol 1996; 40 (Suppl 1): 30S.
   Google Scholar
• Davidson J, Keane T, Brown D, et al. Surgical salvage after radiotherapy for advanced laryngopharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 1997; 123: 420–4.
   PubMedGoogle Scholar
• Dische S, Saunders M, Barrett A, Harve A, Gibson D, Parmar M. A randomized multicenter trial of CHART versus conven-tional radiotherapy in head and neck cancer. Radiother Oncol 1997; 44: 123–36.
   PubMed Web of Science ®Google Scholar
• Horiot JC, Bontemps P, van den Bogaert W, et al. Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers: results of the EORTC 22851 randomized trial. Radiother Oncol 1997; 44: 111–21.
   Google Scholar
• Van den Bogaert W, van der Schueren E, Horiot JC, et al. The feasibility of high dose multiple daily fractionation and its combination with anoxic cell sensitizers in the treatment of head and neck cancer. Int J Radiat Oncol Biol Phys 1982; 8: 1649–55.
   PubMed Web of Science ®Google Scholar
• Ang KK. Accelerated fractionation: what is the price for speeding? Radiother Oncol 1997; 44: 97–9.
   PubMedGoogle Scholar
• Coyle D, Drummond M. Costs of conventional radical radio-therapy versus continuous hyperfractionated accelerated radi-cal radiotherapy (CHART) in the treatment of patients with head and neck cancer or carcinoma of the bronchus Medical Research Council CHART Steering Committee. Clin Oncol 1997; 9: 313–21.
   Google Scholar
• Stuschke M, Thames HD. Hyperfractionated radiotherapy of human tumors: overview of the randomized clinical trials. Int J Radiat Oncol Biol Phys 1997; 37: 259–67.
   PubMed Web of Science ®Google Scholar
• Sanchiz F, Milla A, Torner J, Bonet F, Artola N, Carreno L. Single fraction per day vs. two fractions per day vs. ra-diochemotherapy in the treatment of head and neck cancer. Int J Radiat Oncol Biol Phys 1990; 19: 1347–50.
   PubMed Web of Science ®Google Scholar
• Horiot JC, Le Fur R, Nguyen TD, et al. Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy. Radiother Oncol 1992; 25: 231–41.
   PubMed Web of Science ®Google Scholar
• Datta NR, Choudhry AD, Gupta S, Bose AK. Twice a day versus once a day radiation therapy in head and neck cancer (abstract). Int J Radiat Oncol Biol Phys 1989; 17 (Suppl 1): 132S–133.
   Google Scholar
• Pinto LHJ, Canary PCV, Araajo CMM, Bacelar SC, Souhami L. Prospective randomized trial comparing hyperfractionated vs. conventional radiotherapy in stages III and IV oropharyn-geal carcinoma. Int J Radiat Oncol Biol Phys 1991; 21: 557–62.
   Google Scholar
• Beck-Bornholdt HP, Dubben HH, Liertz-Petersen C, Willers H. Hyperfractionation: where do we stand? Radiother Oncol 1997; 43: 1–21.
   PubMed Web of Science ®Google Scholar