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LETTERS TO THE EDITOR

Fatal heart failure in a young adult female sarcoma patient treated with pazopanib

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Pages 1233-1234 | Received 03 Feb 2017, Accepted 14 Feb 2017, Published online: 02 Mar 2017

References

  • van der Graaf WT, Blay JY, Chawla SP, et al. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2012;379:1879–1886.
  • van Marcke C, Ledoux B, Petit B, et al. Rapid and fatal acute heart failure induced by pazopanib. BMJ Case Rep. 2015. DOI: 10.1136/bcr-2015-211522
  • Suttle AB, Ball HA, Molimard M, et al. Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma. Br J Cancer. 2014;111:1909–1916.
  • Chung RT, Stravitz RT, Fontana RJ, et al. Pathogenesis of liver injury in acute liver failure. Gastroenterology. 2012;143:1–7.
  • Ghatalia P, Morgan CJ, Je Y, et al. Congestive heart failure with vascular endothelial growth factor receptor tyrosine kinase inhibitors. Crit Rev Oncol Hematol. 2014;428:216–219.
  • Kapadia S, Hapani S, Choueriri TK, et al. Risk of liver toxicity with the angiogenesis inhibitor pazopanib in cancer patients. Acta Oncol. 2013;52:1202–1212.
  • Klempner SJ, Choueriri TK, Yee E, et al. Severe pazopanib-induced hepatotoxicity: clinical and histologic course in two patients. J Clin Oncol. 2012;30:264–268.