Comparative treatment planning study for mediastinal Hodgkin’s lymphoma: impact on normal tissue dose using deep inspiration breath hold proton and photon therapy

References

• Eich HT, Diehl V, Gorgen H, et al. Intensified chemotherapy and dose-reduced involved-field radiotherapy in patients with early unfavorable Hodgkin's lymphoma: final analysis of the German Hodgkin Study Group HD11 trial. JCO. 2010;28:4199–4206.
   PubMed Web of Science ®Google Scholar
• Engert A, Plütschow A, Eich HT, et al. Reduced treatment intensity in patients with early-stage Hodgkin’s lymphoma. N Engl J Med. 2010;363:640–652.
   PubMed Web of Science ®Google Scholar
• Aleman BM, van den Belt-Dusebout AW, Klokman WJ, et al. Long-term cause-specific mortality of patients treated for Hodgkin's disease. J Clin Oncol. 2003;21:3431–3439.
   PubMed Web of Science ®Google Scholar
• Castellino SM, Geiger AM, Mertens AC, et al. Morbidity and mortality in long-term survivors of Hodgkin lymphoma: a report from the Childhood Cancer Survivor Study. Blood. 2011;117:1806–1816.
   PubMed Web of Science ®Google Scholar
• Ng A, Bernardo M, Weller E, et al. Long-term survival and competing causes of death in patients with early-stage Hodgkin's disease treated at age 50 or younger. J Clin Oncol. 2002;20:2101–2108.
   PubMed Web of Science ®Google Scholar
• Tseng YD, Cutter DJ, Plastaras JP, et al. Evidence-based review on the use of proton therapy in lymphoma from the Particle Therapy Cooperative Group (PTCOG) lymphoma subcommittee. Int J Radiat Oncol Biol Phys. 2017;99:825–842.
   PubMed Web of Science ®Google Scholar
• Maraldo MV, Specht L. A decade of comparative dose planning studies for early-stage Hodgkin lymphoma: what can we learn? Int J Radiat Oncol Biol Phys. 2014;90:1126–1135.
   PubMed Web of Science ®Google Scholar
• Specht L, Yahalom J, Illidge T, et al. Modern radiation therapy for Hodgkin lymphoma: field and dose guidelines from the international lymphoma radiation oncology group (ILROG). Int J Radiat Oncol Biol Phys. 2014;89:854–862.
   PubMed Web of Science ®Google Scholar
• Voong KR, McSpadden K, Pinnix CC, et al. Dosimetric advantages of a "butterfly" technique for intensity-modulated radiation therapy for young female patients with mediastinal Hodgkin's lymphoma. Radiat Oncol. 2014;9:94.
   PubMed Web of Science ®Google Scholar
• Lohr F, Georg D, Cozzi L, et al. Novel radiotherapy techniques for involved-field and involved-node treatment of mediastinal Hodgkin lymphoma: when should they be considered and which questions remain open? Strahlenther Onkol. 2014;190:864–871.
   PubMed Web of Science ®Google Scholar
• Fiandra C, Filippi AR, Catuzzo P, et al. Different IMRT solutions vs. 3D-conformal radiotherapy in early stage Hodgkin’s lymphoma: dosimetric comparison and clinical considerations. Radiat Oncol. 2012;7:186.
   PubMed Web of Science ®Google Scholar
• Stromberg JS, Sharpe MB, Kim LH, et al. Active breathing control (ABC) for Hodgkin's disease: reduction in normal tissue irradiation with deep inspiration and implications for treatment. Int J Radiat Oncol Biol Phys. 2000;48:797–806.
   PubMed Web of Science ®Google Scholar
• Paumier A, Ghalibafian M, Gilmore J, et al. Dosimetric benefits of intensity-modulated radiotherapy combined with the deep-inspiration breath-hold technique in patients with mediastinal Hodgkin's lymphoma. Int J Radiat Oncol Biol Phys. 2012;82:1522–1527.
   PubMed Web of Science ®Google Scholar
• Petersen PM, Aznar MC, Berthelsen AK, et al. Prospective phase II trial of image-guided radiotherapy in Hodgkin lymphoma: benefit of deep inspiration breath-hold. Acta Oncol. 2015;54:60–66.
   PubMed Web of Science ®Google Scholar
• Charpentier AM, Conrad T, Sykes J, et al. Active breathing control for patients receiving mediastinal radiation therapy for lymphoma: impact on normal tissue dose. Pract Radiat Oncol. 2014;4:174–180.
   PubMedGoogle Scholar
• Aznar MC, Maraldo MV, Schut DA, et al. Minimizing late effects for patients with mediastinal Hodgkin lymphoma: deep inspiration breath-hold, IMRT, or both? Int J Radiat Oncol Biol Phys. 2015;92:169–174.
   PubMed Web of Science ®Google Scholar
• Hoppe BS, Flampouri S, Zaiden R, et al. Involved-node proton therapy in combined modality therapy for Hodgkin lymphoma: results of a phase 2 study. Int J Radiat Oncol Biol Phys. 2014;89:1053–1059.
   PubMed Web of Science ®Google Scholar
• Chera BS, Rodriguez C, Morris CG, et al. Dosimetric comparison of three different involved nodal irradiation techniques for stage II Hodgkin's lymphoma patients: conventional radiotherapy, intensity-modulated radiotherapy, and three-dimensional proton radiotherapy. Int J Radiat Oncol Biol Phys. 2009;75:1173–1180.
   PubMed Web of Science ®Google Scholar
• Li J, Dabaja B, Reed V, et al. Rationale for and preliminary results of proton beam therapy for mediastinal lymphoma. Int J Radiat Oncol Biol Phys. 2011;81:167–174.
   PubMed Web of Science ®Google Scholar
• Enmark M, Lundkvist N, Fager M, et al. PTC17-0493: Clinical Commissioning of Gated Proton Pencil Beam Scanning. Additional Proceedings to the 56th Annual Meeting of the Particle Therapy Cooperative Group (PTCOG). Int J Part Ther. 2017;4:39.
   PubMedGoogle Scholar
• Baues C, Marnitz S, Engert A, et al. Proton versus photon deep inspiration breath hold technique in patients with Hodgkin lymphoma and mediastinal radiation: a planning comparison of deep inspiration breath hold intensity modulation radiotherapy and intensity modulated proton therapy. Radiat Oncol. 2018;13:122.
   PubMed Web of Science ®Google Scholar
• Rechner LA, Maraldo MV, Vogelius IR, et al. Life years lost attributable to late effects after radiotherapy for early stage Hodgkin lymphoma: the impact of proton therapy and/or deep inspiration breath hold. Radiother Oncol. 2017;125:41–47.
   PubMed Web of Science ®Google Scholar
• Edvardsson A, Nilsson MP, Amptoulach S, et al. Comparison of doses and NTCP to risk organs with enhanced inspiration gating and free breathing for left-sided breast cancer radiotherapy using the AAA algorithm. Radiat Oncol. 2015;10:84.
   PubMed Web of Science ®Google Scholar
• Kugele M, Edvardsson A, Berg L, et al. Dosimetric effects of intrafractional isocenter variation during deep inspiration breath-hold for breast cancer patients using surface-guided radiotherapy. J Appl Clin Med Phys. 2018;19:25–38.
   PubMed Web of Science ®Google Scholar
• Flejmer AM, Edvardsson A, Dohlmar F, et al. Respiratory gating for proton beam scanning versus photon 3D-CRT for breast cancer radiotherapy. Acta Oncol. 2016;55:577–583.
   PubMed Web of Science ®Google Scholar
• Paddick I. A simple scoring ratio to index the conformity of radiosurgical treatment plans. Technical note. J Neurosurg. 2000;93 Suppl.3: 219–222.
   PubMed Web of Science ®Google Scholar
• Bert C, Durante M. Motion in radiotherapy: particle therapy. Phys Med Biol. 2011;56:R113–R144.
   PubMed Web of Science ®Google Scholar
• Edvardsson A, Nordstrom F, Ceberg C, et al. Motion induced interplay effects for VMAT radiotherapy. Phys Med Biol. 2018;63:085012.
   PubMed Web of Science ®Google Scholar
• Liu W, Zhang X, Li Y, et al. Robust optimization of intensity modulated proton therapy. Med Phys. 2012;39:1079–1091.
   PubMed Web of Science ®Google Scholar
• Li Y, Niemela P, Liao L, et al. Selective robust optimization: a new intensity-modulated proton therapy optimization strategy. Med Phys. 2015;42:4840–4847.
   PubMed Web of Science ®Google Scholar
• Zeng C, Plastaras JP, Tochner ZA, et al. Proton pencil beam scanning for mediastinal lymphoma: the impact of interplay between target motion and beam scanning. Phys Med Biol. 2015;60:3013–3029.
   PubMed Web of Science ®Google Scholar
• Enmark M, Olofsson J, Ceberg S, Jonsson J. [P205] The impact on pencil beam scanning (PBS) proton therapy for mediastinal lymphoma from deep inspiation breath-hold (DIBH) variability. Phys Med. 2018;52:159.
   Google Scholar
• Prescribing, Recording, and Reporting Proton-beam Therapy. ICRU Report 78 2007.
   Google Scholar
• Paganetti H. Relative biological effectiveness (RBE) values for proton beam therapy. Variations as a function of biological endpoint, dose, and linear energy transfer. Phys Med Biol. 2014;59:R419–R472.
   PubMed Web of Science ®Google Scholar