Sex steroid hormone receptor expression in the vaginal wall in cervical cancer survivors after radiotherapy

References

• Ye S, Yang J, Cao D, et al. A systematic review of quality of life and sexual function of patients with cervical cancer after treatment. Int J Gynecol Cancer. 2014;24:1146–1157.
   PubMed Web of Science ®Google Scholar
• Bergmark K, Avall-Lundqvist E, Dickman PW, et al. Vaginal changes and sexuality in women with a history of cervical cancer. N Engl J Med. 1999;340:1383–1389.
   PubMed Web of Science ®Google Scholar
• Jensen PT, Groenvold M, Klee MC, et al. Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys. 2003;56:937–949.
   PubMed Web of Science ®Google Scholar
• North American Menopause S. The role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women: 2007 position statement of The North American Menopause Society. Menopause. 2007;14:355–369, quiz 70–1.
   PubMed Web of Science ®Google Scholar
• Hofsjo A, Bohm-Starke N, Blomgren B, et al. Radiotherapy-induced vaginal fibrosis in cervical cancer survivors. Acta Oncol. 2017;56:661–666.
   Web of Science ®Google Scholar
• Pitkin J, Rees MC, Gray S, et al. Management of premature menopause. Menopause Int. 2007;13:44–45.
   PubMedGoogle Scholar
• Lethaby A, Ayeleke RO, Roberts H. Local oestrogen for vaginal atrophy in postmenopausal women. Cochrane Database Syst Rev. 2016;31:CD001500.
   PubMed Web of Science ®Google Scholar
• Pitkin RM, Bradbury JT. The effect of topical estrogen on irradiated vaginal epithelium. Am J Obstet Gynecol. 1965;92:175–182.
   PubMed Web of Science ®Google Scholar
• Pitkin RM, VanVoorhis LW. Postirradiation vaginitis. An evaluation of prophylaxis with topical estrogen. Radiology. 1971;99:417–421.
   PubMed Web of Science ®Google Scholar
• Abitbol MM, Davenport JH. The irradiated vagina. Obstet Gynecol. 1974;44:249–256.
   PubMed Web of Science ®Google Scholar
• Denton AS, Maher EJ. Interventions for the physical aspects of sexual dysfunction in women following pelvic radiotherapy. Cochrane Database Syst Rev. 2003;1:CD003750.
   PubMedGoogle Scholar
• Hofsjo A, Bergmark K, Blomgren B, et al. Radiotherapy for cervical cancer – impact on the vaginal epithelium and sexual function. Acta Oncol. 2018;57:338–345.
   PubMed Web of Science ®Google Scholar
• Sodergard R, Backstrom T, Shanbhag V, et al. Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature. J Steroid Biochem. 1982;16:801–810.
   PubMedGoogle Scholar
• Isaksson E, Wang H, Sahlin L, et al. Effects of long-term HRT and tamoxifen on the expression of progesterone receptors A and B in breast tissue from surgically postmenopausal cynomolgus macaques. Breast Cancer Res Treat. 2003;79:233–239.
   PubMed Web of Science ®Google Scholar
• Stomati M, Hartmann B, Spinetti A, et al. Effects of hormonal replacement therapy on plasma sex hormone-binding globulin, androgen and insulin-like growth factor-1 levels in postmenopausal women. J Endocrinol Invest. 1996;19:535–541.
   PubMed Web of Science ®Google Scholar
• Gebhart JB, Rickard DJ, Barrett TJ, et al. Expression of estrogen receptor isoforms alpha and beta messenger RNA in vaginal tissue of premenopausal and postmenopausal women. Am J Obstet Gynecol. 2001;185:1325–1330; discussion 30–31.
   PubMed Web of Science ®Google Scholar
• Soderberg MW, Johansson B, Masironi B, et al. Pelvic floor sex steroid hormone receptors, distribution and expression in pre- and postmenopausal stress urinary incontinent women. Acta Obstet Gynecol Scand. 2007;86:1377–1384.
   PubMed Web of Science ®Google Scholar
• Chen GD, Oliver RH, Leung BS, et al. Estrogen receptor alpha and beta expression in the vaginal walls and uterosacral ligaments of premenopausal and postmenopausal women. Fertil Steril. 1999;71:1099–1102.
   PubMed Web of Science ®Google Scholar
• Fuermetz A, Schoenfeld M, Ennemoser S, et al. Change of steroid receptor expression in the posterior vaginal wall after local estrogen therapy. Eur J Obstet Gynecol Reprod Biol. 2015;187:45–50.
   PubMed Web of Science ®Google Scholar
• Sawczuk B, Gołębiewska M, Mazurek A, et al. Immunohistochemical evaluation of oestrogen receptors alpha and beta in epithelium of the vaginal mucous membrane in women after oestrogen therapy. PM. 2017;1:12–18.
   Google Scholar
• Baldassarre M, Perrone AM, Giannone FA, et al. Androgen receptor expression in the human vagina under different physiological and treatment conditions. Int J Impot Res. 2013;25:7–11.
   PubMed Web of Science ®Google Scholar
• Kizilay F, Gali HE, Serefoglu EC. Diabetes and sexuality. Sex Med Rev. 2017;5:45–51.
   PubMed Web of Science ®Google Scholar
• Baldassarre M, Alvisi S, Berra M, et al. Changes in vaginal physiology of menopausal women with type 2 diabetes. J Sex Med. 2015;12:1346–1355.
   PubMed Web of Science ®Google Scholar
• Traish AM, Kim NN, Huang YH, et al. Sex steroid hormones differentially regulate nitric oxide synthase and arginase activities in the proximal and distal rabbit vagina. Int J Impot Res. 2003;15:397–404.
   PubMed Web of Science ®Google Scholar
• Pessina MA, Hoyt RF, Jr., Goldstein I, et al. Differential regulation of the expression of estrogen, progesterone, and androgen receptors by sex steroid hormones in the vagina: immunohistochemical studies. J Sex Med. 2006;3:804–814.
   PubMed Web of Science ®Google Scholar
• Lipson KE, Wong C, Teng Y, et al. CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis. Fibrogenesis Tissue Repair. 2012;5:S24.
   PubMedGoogle Scholar