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ORIGINAL ARTICLES: MEDICAL ONCOLOGY

Circulating hematopoietic stem cells, endothelial progenitor cells and cancer stem cells in hepatocellular carcinoma patients: contribution to diagnosis and prognosis

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Pages 33-39 | Received 02 Jan 2019, Accepted 15 Aug 2019, Published online: 03 Sep 2019

References

  • Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:E359–E386.
  • Hetta HF, Zahran AM, Mansor SG, et al. Frequency and Implications of myeloid-derived suppressor cells and lymphocyte subsets in Egyptian patients with hepatitis C virus-related hepatocellular carcinoma. J Med Virol. 2019;91:1319.
  • Zahran AM, Abdel-Meguid MM, Ashmawy AM, et al. Frequency and implications of natural killer and natural killer T cells in hepatocellular carcinoma. Egypt J Immunol. 2018;25:45–52.
  • Chaturvedi VK, Singh A, Dubey SK, et al. Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma. Microb Pathog. 2019;128:184–194.
  • Poon RT, Fan ST, Lo CM, et al. Improving survival results after resection of hepatocellular carcinoma: a prospective study of 377 patients over 10 years. Ann Surg. 2001;234:63–70.
  • T P Poon R, Ng K, Lam C-M, et al. Effectiveness of radiofrequency ablation for hepatocellular carcinomas larger than 3 cm in diameter. Arch Surg. 2004;139:281–287.
  • Abd Ellah NH, Tawfeek HM, John J, et al. Nanomedicine as a future therapeutic approach for hepatitis C virus. Nanomedicine. 2019;14:1471–1491.
  • Hassan EA, Ahmed EH, Nafee AM, et al. Regulatory T cells, IL10 and IL6 in HCV related hepatocellular carcinoma after transarterial chemoembolization (TACE). Egypt J Immunol. 2019;26:69–78.
  • Ng KT, Poon R, Lo C-M, et al. Analysis of recurrence pattern and its influence on survival outcome after radiofrequency ablation of hepatocellular carcinoma. J Gastrointest Surg. 2008;12:183–191.
  • Knudsen ES, Gopal P, Singal AG. The changing landscape of hepatocellular carcinoma: etiology, genetics, and therapy. Am J Pathol. 2014;184:574–583.
  • Mazzanti R, Arena U, Tassi R. Hepatocellular carcinoma: where are we? World J Exp Med. 2016;6:21–36.
  • Hetta HF, Elkady A, Tohamy TA, et al. Regulatory B cells: key players in hepatocellular carcinoma progression. Gastroenterol Hepatol Open Access. 2016;5:00136.
  • Ho JW, Pang RW, Lau C, et al. Significance of circulating endothelial progenitor cells in hepatocellular carcinoma. Hepatology. 2006;44:836–843.
  • Ding Y-t, Kumar S, Yu D-C. The role of endothelial progenitor cells in tumour vasculogenesis. Pathobiology. 2008;75:265–273.
  • Yang ZF, Poon RT. Vascular changes in hepatocellular carcinoma. Anat Rec (Hoboken). 2008;291:721–734.
  • Chen C-H, Li C, Tung W-C, et al. Levels and values of circulating endothelial progenitor cells, soluble angiogenic factors, and mononuclear cell apoptosis in liver cirrhosis patients. J Biomed Sci. 2012;19:66.
  • Rafii S. Circulating endothelial precursors: mystery, reality, and promise. J Clin Invest. 2000;105:17–19.
  • Lyden D, Hattori K, Dias S, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med. 2001;7:1194–1201.
  • Yu D, Sun X, Qiu Y, et al. Identification and clinical significance of mobilized endothelial progenitor cells in tumor vasculogenesis of hepatocellular carcinoma. Clin Cancer Res. 2007;13:3814–3824.
  • Sieghart W, Fellner S, Reiberger T, et al. Differential role of circulating endothelial progenitor cells in cirrhotic patients with or without hepatocellular carcinoma. Dig Liver Dis. 2009;41:902–906.
  • Yu D-C, Chen J, Sun X-t, et al. Mechanism of endothelial progenitor cell recruitment into neo-vessels in adjacent non-tumor tissues in hepatocellular carcinoma. BMC Cancer. 2010;10:435.
  • Zhu H, Shao Q, Sun X, et al. The mobilization, recruitment and contribution of bone marrow-derived endothelial progenitor cells to the tumor neovascularization occur at an early stage and throughout the entire process of hepatocellular carcinoma growth. Oncol Rep. 2012;28:1217–1224.
  • Gadelhak NA, Gadelhak SA, El Morsi DA, et al. Prognostic significance of three hepatitis markers (p53 antibodies, vascular endothelial growth factors and alpha fetoprotein) in patients with hepatocellular carcinoma. Hepatogastroenterology. 2009;56:1417–1424.
  • Fürstenberger G, von Moos R, Lucas R, et al. Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer. Br J Cancer. 2006;94:524–531.
  • Mellick A, Plummer P, Nolan D, et al. Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth. Cancer Res. 2010;70:7273–7282.
  • Bralet MP, Pichard V, Ferry N. Demonstration of direct lineage between hepatocytes and hepatocellular carcinoma in diethylnitrosamine-treated rats. Hepatology (Baltimore, Md). 2002;36:623–630.
  • Zahran AM, Aly SS, Rayan A, et al. Survival outcomes of CD34(+)CD38(–)LSCs and their expression of CD123 in adult AML patients. Oncotarget. 2018;9:34056–34065.
  • Zahran AM, Rayan A, Fakhry H, et al. Pretreatment detection of circulating and tissue CD133(+) CD44(+) cancer stem cells as a prognostic factor affecting the outcomes in Egyptian patients with colorectal cancer. Cancer Manag Res. 2019;11:1237–1248.
  • Tsai KS, Yang SH, Lei YP, et al. Mesenchymal stem cells promote formation of colorectal tumors in mice. Gastroenterology. 2011;141:1046–1056.
  • Lugli A, Iezzi G, Hostettler I, et al. Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. Br J Cancer. 2010;103:382–390.
  • Pang RW, Poon RT. Cancer stem cell as a potential therapeutic target in hepatocellular carcinoma. Curr Cancer Drug Targets. 2012;112:1081–1094.
  • Otto W, Krol M, Maciaszczyk M, et al. Levels and values of circulating hematopoietic and endothelial progenitor cells in patients with hepatocellular carcinoma. J Liver. 2014;03:167.
  • Zahran AM, Aly SS, Altayeb HA, et al. Circulating endothelial cells and their progenitors in acute myeloid leukemia. Oncol Lett. 2016;12:1965–1970.
  • Zhu Z, Hao X, Yan M, et al. Cancer stem/progenitor cells are highly enriched in CD133 + CD44+ population in hepatocellular carcinoma. Int J Cancer. 2010;126:2067–2078.
  • Mansour AH, Elkhoda TR, Ayyad RS, et al. Regulation of cancer stem cell marker (CD133) by transforming growth factor beta in hepatocellular carcinoma. Int J Cancer Res. 2014;10:65–73.
  • Song W, Li H, Tao K, et al. Expression and clinical significance of the stem cell marker CD133 in hepatocellular carcinoma. Int J Clin Pract. 2008;62:1212–1218.
  • Yeh CT, Kuo CJ, Lai MW, et al. CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection. BMC Cancer. 2009;9:324.
  • Sasaki A, Kamiyama T, Yokoo H, et al. Cytoplasmic expression of CD133 is an important risk factor for overall survival in hepatocellular carcinoma. Oncol Rep. 2010;24:537–546.
  • Hirohashi K, Yamamoto T, Uenishi T, et al. CD44 and VEGF expression in extrahepatic metastasis of human hepatocellular carcinoma. Hepato-gastroenterology. 2004;51:1121–1123.
  • Zahran AM, Nafady-Hego H, Mansor SG, et al. Increased frequency and FOXP3 expression of human CD8+ CD25High + lymphocytes and its relation to CD4 T regulatory cells in patients with hepatocellular carcinoma. Hum Immunol. 2019;80:510.
  • Zahran AM, Zahran ZAM, El-Badawy O, et al. Prognostic impact of toll-like receptors 2 and 4 expression on monocytes in Egyptian patients with hepatocellular carcinoma. Immunol Res. 2019.
  • Bruix J, Sherman M. Management of hepatocellular carcinoma: an update. Hepatology (Baltimore, Md). 2011;53:1020–1022.
  • Cancer EAFTSOTLEOFRATO. EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol. 2012;56:908–943.
  • Giannini EG, Testa R, Savarino V. Liver enzyme alteration: a guide for clinicians. CMAJ: Can Med Assoc J = journal de l'Association medicale canadienne. 2005;172:367–379.
  • Yang XR, Xu Y, Yu B, et al. High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma. Gut. 2010;59:953–962.
  • Liu R, Shen Y, Nan K, et al. Association between expression of cancer stem cell markers and poor differentiation of hepatocellular carcinoma: a meta-analysis (PRISMA). Medicine. 2015;94:e1306.
  • Vilchez V, Zaytseva Y, Stewart R, et al. Liver cancer stem cell markers (CD133+/CD44+) are strongly associated with moderate to poorly differentiated hepatocellular carcinoma in patients undergoing transplantation.: Abstract# A387. Transplantation. 2014;98:697.
  • Romano M, De Francesco F, Pirozzi G, et al. Expression of cancer stem cell biomarkers as a tool for a correct therapeutic approach to hepatocellular carcinoma. Oncoscience. 2015;2:443–456.
  • Guo Z, Li LQ, Jiang JH, et al. Cancer stem cell markers correlate with early recurrence and survival in hepatocellular carcinoma. World J Gastroenterol. 2014;20:2098–2106.
  • Chan AW, Tong JH, Chan SL, et al. Expression of stemness markers (CD133 and EpCAM) in prognostication of hepatocellular carcinoma. Histopathology. 2014;64:935–950.

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