A randomized phase-II study of reirradiation and hyperthermia versus reirradiation and hyperthermia plus chemotherapy for locally recurrent breast cancer in previously irradiated area

References

• Bedwinek JM, Fineberg B, Lee J, et al. Analysis of failures following local treatment of isolated local-regional recurrence of breast cancer. Int J Radiat Oncol Biol Phys. 1981;7(5):581–585.
   PubMed Web of Science ®Google Scholar
• Richtlijn Borstkanker [Internet]. 2017. [cited 2021 Apr 18]. Available from: http://www.vkng.org.
   Google Scholar
• van der Zee J. Heating the patient: a promising approach? Ann Oncol. 2002;13(8):1173–1184.
   PubMed Web of Science ®Google Scholar
• Falk MH, Issels RD. Hyperthermia in oncology. Int J Hyperthermia. 2001;17(1):1–18.
   PubMed Web of Science ®Google Scholar
• Overgaard J. Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck–a systematic review and meta-analysis. Radiother. Oncol. 2011;100(1):22–32.
   PubMed Web of Science ®Google Scholar
• Dewhirst MW, Vujaskovic Z, Jones E, et al. Re-setting the biologic rationale for thermal therapy. Int J Hyperthermia. 2005;21(8):779–790.
   PubMed Web of Science ®Google Scholar
• Krawczyk PM, Eppink B, Essers J, et al. Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition. Proc Natl Acad Sci USA. 2011;108(24):9851–9856.
   PubMed Web of Science ®Google Scholar
• Elming PB, Sorensen BS, Oei AL, et al. Hyperthermia: the optimal treatment to overcome radiation resistant hypoxia. Cancers. 2019;11(1):60.
   PubMed Web of Science ®Google Scholar
• Oei AL, Kok HP, Oei SB, et al. Molecular and biological rationale of hyperthermia as radio- and chemosensitizer. Adv Drug Deliv Rev. 2020;163–164:84–97.
   PubMed Web of Science ®Google Scholar
• Datta NR, Ordonez SG, Gaipl US, et al. Local hyperthermia combined with radiotherapy and-/or chemotherapy: recent advances and promises for the future. Cancer Treat Rev. 2015;41(9):742–753.
   PubMed Web of Science ®Google Scholar
• van der Zee J, van der Holt B, Rietveld PJM, et al. Reirradiation combined with hyperthermia in recurrent breast cancer results in a worthwhile local palliation. Br J Cancer. 1999;79(3–4):483–490.
   PubMed Web of Science ®Google Scholar
• Jones EL, Oleson JR, Prosnitz LR, et al. Randomized trial of hyperthermia and radiation for superficial tumors. J Clin Oncol. 2005;23(13):3079–3085.
   PubMed Web of Science ®Google Scholar
• Jones EL, Marks LB, Prosnitz LR. Point: hyperthermia with radiation for chest wall recurrences. J Natl Compr Canc Netw. 2007;5(3):339–344.
   PubMedGoogle Scholar
• Li G, Mitsumori M, Ogura M, et al. Local hyperthermia combined with external irradiation for regional recurrent breast carcinoma. Int J Clin Oncol. 2004;9(3):179–183.
   PubMedGoogle Scholar
• Wahl AO, Rademaker A, Kiel KD, et al. Multi-Institutional review of repeat irradiation of chest wall and breast for recurrent breast cancer. Int J Radiat Oncol Biol Phys. 2008;70(2):477–484.
   PubMed Web of Science ®Google Scholar
• Overgaard J, Radacic MM, Grau C. Interaction of hyperthermia and m-Diamminedichloroplatinum(II) alone or combined with radiation in a C3H mammary carcinoma in vivo. Cancer Res. 1991;51(2):707–711.
   Web of Science ®Google Scholar
• Vernon CC, Hand JW, Field SB, et al. Radiotherapy with or without hyperthermia in the treatment of superficial localized breast cancer: results from five randomized controlled trials. Int J Radiat Oncol Biol Phys. 1996;35:731–744.
   PubMed Web of Science ®Google Scholar
• van Driel WJ, Koole SN, Sikorska K, et al. Hyperthermic intraperitoneal chemotherapy in ovarian cancer. N Engl J Med. 2018;378(3):230–240.
   PubMed Web of Science ®Google Scholar
• Rietbroek RC, Schilthuis MS, Bakker PJM, et al. Phase II trial of weekly locoregional hyperthermia and cisplatin in patients with a previously irradiated recurrent carcinoma of the uterine cervix. Cancer. 1997;79(5):935–943.
   PubMed Web of Science ®Google Scholar
• Hettinga JVE, Konings AWT, Kampinga HH. Reduction of cellular cisplatin resistance by hyperthermia-a review. Int J Hyperthermia. 1997;13(5):439–457.
   PubMed Web of Science ®Google Scholar
• Rietbroek RC, Schilthuis MS, van der Zee J, et al. Hyperthermia in combination with chemotherapy in gynaecological tumours. Ned Tijdschr Geneeskd. 1999;143:85–88.
   PubMedGoogle Scholar
• Schaake-Koning C, van den Bogaert W, Dalesio O, et al. Effects of concomitant cisplatin and radiotherapy on inoperable non-small-cell lung cancer. N Engl J Med. 1992;326(8):524–530.
   PubMed Web of Science ®Google Scholar
• Pearcey R, Brundage M, Drouin P, et al. Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. J Clin Oncol. 2002;20(4):966–972.
   PubMed Web of Science ®Google Scholar
• Westermann AM, Jones EL, Schem BC, et al. First results of triple-modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with stage IIB, III, and IVA cervical carcinoma. Cancer. 2005;104(4):763–770.
   PubMed Web of Science ®Google Scholar
• Ohguri T, Harima Y, Imada H, et al. Relationships between thermal dose parameters and the efficacy of definitive chemoradiotherapy plus regional hyperthermia in the treatment of locally advanced cervical cancer: data from a multicentre randomised clinical trial. Int J Hypertherm. 2018;34(4):461–468.
   PubMed Web of Science ®Google Scholar
• Wang Y, Hong W, Che S, et al. Outcomes for hyperthermia combined with concurrent radiochemotherapy for patients with cervical cancer. Int J Radiat Oncol Biol Phys. 2020;107(3):499–511.
   PubMed Web of Science ®Google Scholar
• Herman TS, Teicher BA. Summary of studies adding systemic chemotherapy to local hyperthermia and radiation. Int. J. Hypertherm. 1994;10(3):443–449.
   PubMed Web of Science ®Google Scholar
• Bornstein BA, Zouranjian PS, Hansen JL, et al. Local hyperthermia, radiation therapy, and chemotherapy in patients with local-regional recurrence of breast carcinoma. Int J Radiat Oncol Biol Phys. 1993;25(1):79–85.
   PubMed Web of Science ®Google Scholar
• Zagar TM, Higgins KA, Miles EF, et al. Durable palliation of breast cancer chest wall recurrence with radiation therapy, hyperthermia, and chemotherapy. Radiother Oncol. 2010;97(3):535–540.
   PubMed Web of Science ®Google Scholar
• Oldenborg S, Griesdoorn V, van Os R, et al. Reirradiation and hyperthermia for irresectable locoregional recurrent breast cancer in previously irradiated area: size matters. Radiother Oncol. 2015;117(2):223–228.
   PubMed Web of Science ®Google Scholar
• Trefna HD, Crezee H, Schmidt M, et al. Quality assurance guidelines for superficial hyperthermia clinical trials: I. Clinical requirements. Int J Hypertherm. 2017;33(4):471–482.
   PubMed Web of Science ®Google Scholar
• van Stam G, Kok HP, Hulshof MCCM, et al. A flexible 70 MHz phase-controlled double waveguide system for hyperthermia treatment of superficial tumours with deep infiltration. Int J Hyperthermia. 2017;33(7):796–809.
   PubMed Web of Science ®Google Scholar
• Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst. 2000;92(3):205–216.
   PubMed Web of Science ®Google Scholar
• Kouloulias VE, Dardoufas CE, Kouvaris JR, et al. Liposomal doxorubicin in conjunction with reirradiation and local hyperthermia treatment in recurrent breast cancer: a phase I/II trial. Clin Cancer Res. 2002;8:374–382.
   PubMed Web of Science ®Google Scholar
• Zagar TM, Vujaskovic Z, Formenti S, et al. Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer. Int J Hyperth. 2014;30(5):285–294.
   PubMed Web of Science ®Google Scholar
• Lindholm CE, Kjellen E, Nilsson P, et al. Microwave-induced hyperthermia and radiotherapy in human superficial tumours: clinical results with a comparative study of combined treatment versus radiotherapy alone. Int J Hyperth. 1987;3(5):393–411.
   PubMed Web of Science ®Google Scholar
• Oldenborg S, Rasch CRN, van Os R, et al. Reirradiation + hyperthermia for recurrent breast cancer en cuirasse. Strahlenther Onkol. 2018;194(3):206–214.
   PubMed Web of Science ®Google Scholar
• van den Tempel N, Laffeber C, Odijk H, et al. The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination. Oncotarget. 2017;8(27):44593–44604.
   PubMedGoogle Scholar
• Bergs JWJ, Haveman J, ten Cate R, et al. Effect of 41 °C and 43 °C on cisplatin radiosensitization in two human carcinoma cell lines with different sensitivities for cisplatin. Oncol Rep. 2007;18:219–226.
   PubMed Web of Science ®Google Scholar
• Bakker A, Kolff MW, Holman R, et al. Thermal skin damage during reirradiation and hyperthermia is time-temperature dependent. Int J Radiat Oncol Biol Phys. 2017;98(2):392–399.
   PubMed Web of Science ®Google Scholar
• Bakker A, van der Zee J, van Tienhoven G, et al. Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review. Int J Hyperth. 2019;36(1):1023–1038.
   Web of Science ®Google Scholar
• Overgaard J. Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo. Int J Radiat Oncol Biol Phys. 1980;6(11):1507–1517.
   PubMed Web of Science ®Google Scholar
• Datta NR, Puric E, Klingbiel D, et al. Hyperthermia and radiation therapy in locoregional recurrent breast cancers: a systematic review and meta-analysis. Int J Radiat Oncol Biol Phys. 2016;94(5):1073–1087.
   PubMed Web of Science ®Google Scholar
• Flameling B, Nordberg T, Ott O, et al. An international multicenter phase III study of chemoradiotherapy versus chemoradiotherapy plus hyperthermia for locally advanced cervical cancer. J Clin Oncol. 2016;34(15_suppl):e17023.
   Web of Science ®Google Scholar
• Song CW. Effect of local hyperthermia on blood flow and microenvironment: a review. Cancer Res. 1984;44:4721–4730.
   PubMed Web of Science ®Google Scholar
• Crezee H, van Leeuwen CM, Oei AL, et al. Thermoradiotherapy planning: integration in routine clinical practice. Int J Hyperth. 2016;32(1):41–49.
   PubMed Web of Science ®Google Scholar
• Oei AL, Vriend LEM, Crezee J, et al. Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all. Radiation Oncol. 2015;10:165.
   PubMed Web of Science ®Google Scholar
• Issels R, Kampmann E, Kanaar R, et al. Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application. Int J Hyperth. 2016;32(1):89–95.
   PubMed Web of Science ®Google Scholar
• van den Tempel N, Odijk H, van Holthe N, et al. Heat-induced BRCA2 degradation in human tumours provides rationale for hyperthermia-PARP-inhibitor combination therapies. Int J Hyperth. 2018;34(4):407–414.
   PubMed Web of Science ®Google Scholar
• Vriend LEM, van den Tempel N, Oei AL, et al. Boosting the effects of hyperthermia-based anticancer treatments by HSP90 inhibition. Oncotar. 2017;8(57):97490–97503.
   PubMedGoogle Scholar