3,366
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Exercise prehabilitation for people with myeloma undergoing autologous stem cell transplantation: results from PERCEPT pilot randomised controlled trial

ORCID Icon, , , , , & ORCID Icon show all
Pages 696-705 | Received 15 Oct 2022, Accepted 06 Feb 2023, Published online: 15 Feb 2023

References

  • Brown K. 2017. Blood cancer in a nutshell: classification and investigation. Available from: http://blogs.biomedcentral.com/on-medicine/2017/09/01/blood-cancer-in-a-nutshell-classification-and-investigation/.
  • Zhou L, Yu Q, Wei G, et al. Measuring the global, regional, and national burden of multiple myeloma from 1990 to 2019. BMC Cancer. 2021;21(1):606.
  • Haematological Malignancy Research Network (HMRN). Prevalence statistics 2022; 2022. Available from: https://www.hmrn.org/statistics/prevalence.
  • MyelomaUK. 2018. Symptoms and complications. Available from: https://www.myeloma.org.uk/information/symptoms-and-complications/.
  • Nishimura KK, Barlogie B, van Rhee F, et al. Long-term outcomes after autologous stem cell transplantation for multiple myeloma. Blood Adv. 2020;4(2):422–431.
  • Allart-Vorelli P, Porro B, Baguet F, et al. Haematological cancer and quality of life: a systematic literature review. Blood Cancer J. 2015;5(4):e305–e305.
  • Gulbrandsen N, Hjermstad MJ, Wisløff F, Nordic Myeloma Study Group. Interpretation of quality of life scores in multiple myeloma by comparison with a reference population and assessment of the clinical importance of score differences. Eur J Haematol. 2004;72(3):172–180.
  • Shapiro YN, Peppercorn JM, Yee AJ, et al. Lifestyle considerations in multiple myeloma. Blood Cancer J. 2021;11(10):172.
  • Nielsen LK, Larsen RF, Jarlbaek L, et al. Health-related quality of life in patients with multiple myeloma participating in a multidisciplinary rehabilitation program. Ann Hematol. 2021;100(9):2311–2323.
  • Terpos E, Ntanasis-Stathopoulos I, Dimopoulos MA. Myeloma bone disease: from biology findings to treatment approaches. Blood. 2019;133(14):1534–1539.
  • Terpos E, Ntanasis-Stathopoulos I, Gavriatopoulou M, et al. Pathogenesis of bone disease in multiple myeloma: from bench to bedside. Blood Cancer J. 2018;8(1):7.
  • Coluzzi F, Rolke R, Mercadante S. Pain management in patients with multiple myeloma: an update. Cancers. 2019;11(12):2037.
  • Davies MP, Fingas S, Chantry A. Mechanisms and treatment of bone pain in multiple myeloma. Curr Opin Support Palliat Care. 2019;13(4):408–416.
  • Land J, Hackett J, Sidhu G, et al. Myeloma patients’ experiences of a supervised physical activity programme: a qualitative study. Support Care Cancer. 2022;30(7):6273–6286.
  • Pulewka K, Wolff D, Herzberg PY, et al. Physical and psychosocial aspects of adolescent and young adults after allogeneic hematopoietic stem-cell transplantation: results from a prospective multicenter trial. J Cancer Res Clin Oncol. 2017;143(8):1613–1619.
  • Coolbrandt A, Grypdonck MHF. Keeping courage during stem cell transplantation: a qualitative research. Europ J Oncol Nurs. 2010;14(3):218–223.
  • Walpole G, Clark H, Dowling M. Myeloma patients’ experiences of haematopoietic stem cell transplant: a qualitative thematic synthesis. Eur J Oncol Nurs. 2018;35:15–21.
  • Craike MJ, Hose K, Courneya KS, et al. Perceived benefits and barriers to exercise for recently treated patients with multiple myeloma: a qualitative study. BMC Cancer. 2013;13:319.
  • Craike M, Hose K, Courneya KS, et al. Physical activity preferences for people living with multiple myeloma: a qualitative study. Cancer Nurs. 2017;40(5):E1–E8.
  • Coon SK, Coleman EA. Exercise decisions within the context of multiple myeloma, transplant, and fatigue. Cancer Nurs. 2004;27(2):108–118.
  • Coleman EA, Coon S, Hall-Barrow J, et al. Feasibility of exercise during treatment for multiple myeloma. Cancer Nurs. 2003;26(5):410–419.
  • Coleman EA, Coon SK, Kennedy RL, et al. Effects of exercise in combination with epoetin alfa during high-dose chemotherapy and autologous peripheral blood stem cell transplantation for multiple myeloma. Oncol Nurs Forum. 2008;35(3):E53–E61.
  • Coleman EA, Goodwin JA, Kennedy R, et al. Effects of exercise on fatigue, sleep, and performance: a randomized trial. Oncol Nurs Forum. 2012;39(5):468–477.
  • Mawson S, Keen C, Skilbeck J, et al. Feasibility and benefits of a structured prehabilitation programme prior to autologous stem cell transplantation (ASCT) in patients with myeloma; a prospective feasibility study. Physiotherapy. 2021;113:88–99.
  • McCourt O, Fisher A, Ramdharry G, et al. PERCEPT myeloma: a protocol for a pilot randomised controlled trial of exercise prehabilitation before and during autologous stem cell transplantation in patients with multiple myeloma. BMJ Open. 2020;10(1):e033176.
  • McCourt O, Fisher A, Ramdharry G, et al. Adaptation of the PERCEPT myeloma prehabilitation trial to virtual delivery: changes in response to the COVID-19 pandemic. BMJ Open. 2022;12(4):e059516.
  • Eldridge SM, Chan CL, Campbell MJ, PAFS consensus group, et al. CONSORT 2010 statement: extension to randomised pilot and feasibility trials. Pilot Feasibility Stud. 2016;2:64.
  • Slade SC, Dionne CE, Underwood M, et al. Consensus on exercise reporting template (CERT): explanation and elaboration statement. Br J Sports Med. 2016;50(23):1428–1437.
  • Kraemer WJ, Ratamess NA. Fundamentals of resistance training: progression and exercise prescription. Med Sci Sports Exerc. 2004;36(4):674–688.
  • Webster K, Cella D, Yost K. The functional assessment of chronic illness therapy (FACIT) measurement system: properties, applications, and interpretation. Health Qual Life Outcomes. 2003;1:79.
  • Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365–376.
  • McQuellon RP, Russell GB, Cella DF, et al. Quality of life measurement in bone marrow transplantation: development of the functional assessment of cancer therapy-bone marrow transplant (FACT-BMT) scale. Bone Marrow Transplant. 1997;19(4):357–368.
  • Pickard AS, De Leon MC, Kohlmann T, et al. Psychometric comparison of the standard EQ-5D to a 5 level version in cancer patients. Med Care. 2007;45(3):259–263.
  • Gibbons WJ, Fruchter N, Sloan S, et al. Reference values for a multiple repetition 6-minute walk test in healthy adults older than 20 years. J Cardiopulm Rehabil. 2001;21(2):87–93.
  • Craig CL, Marshall AL, Sjostrom M, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;35(8):1381–1395.
  • The Jamovi project. Jamovi (version 2.2) [Computer Software]. 2021.
  • Cella D, Eton DT, Lai JS, et al. Combining anchor and distribution-based methods to derive minimal clinically important differences on the functional assessment of cancer therapy (FACT) anemia and fatigue scales. J Pain Symptom Manage. 2002;24(6):547–561.
  • Nordin A, Taft C, Lundgren-Nilsson A, et al. Minimal important differences for fatigue patient reported outcome measures-a systematic review. BMC Med Res Methodol. 2016;16:62.
  • Cella D, Hahn EA, Dineen K. Meaningful change in cancer-specific quality of life scores: differences between improvement and worsening. Qual Life Res. 2002;11(3):207–221.
  • White AC, Terrin N, Miller KB, et al. Impaired respiratory and skeletal muscle strength in patients prior to hematopoietic stem-cell transplantation. Chest. 2005;128(1):145–152.
  • Camilleri M, Bekris G, Sidhu G, et al. The impact of COVID-19 on autologous stem cell transplantation in multiple myeloma: a single-Centre, qualitative evaluation study. Support Care Cancer. 2022;30(9):7469–7479.
  • Wood WA, Weaver M, Smith-Ryan AE, et al. Lessons learned from a pilot randomized clinical trial of home-based exercise prescription before allogeneic hematopoietic cell transplantation. Support Care Cancer. 2020;28(11):5291–5298.
  • van Haren I, Staal JB, Potting CM, et al. Physical exercise prior to hematopoietic stem cell transplantation: a feasibility study. Physiother Theory Pract. 2018;34(10):747–756.
  • Groeneveldt L, Mein G, Garrod R, et al. A mixed exercise training programme is feasible and safe and may improve quality of life and muscle strength in multiple myeloma survivors. BMC Cancer. 2013;13:31.
  • Larsen RF, Jarden M, Minet LR, et al. Supervised and home-based physical exercise in patients newly diagnosed with multiple myeloma-a randomized controlled feasibility study. Pilot Feasibility Stud. 2019;5:130.
  • Koutoukidis DA, Land J, Hackshaw A, et al. Fatigue, quality of life and physical fitness following an exercise intervention in multiple myeloma survivors (MASCOT): an exploratory randomised phase 2 trial utilising a modified Zelen design. Br J Cancer. 2020;123(2):187–195.
  • Larsen RF, Jarden M, Minet LR, et al. Physical function in patients newly diagnosed with multiple myeloma; a Danish Cohort Study. BMC Cancer. 2020;20(1):169.
  • Visek AJ, Olson EA, DiPietro L. Factors predicting adherence to 9 months of supervised exercise in healthy older women. J Phys Act Health. 2011;8(1):104–110.
  • Campagnaro E, Saliba R, Giralt S, et al. Symptom burden after autologous stem cell transplantation for multiple myeloma. Cancer. 2008;112(7):1617–1624.
  • Sherman AC, Simonton S, Latif U, et al. Changes in quality-of-life and psychosocial adjustment among multiple myeloma patients treated with high-dose melphalan and autologous stem cell transplantation. Biol Blood Marrow Transplant. 2009;15(1):12–20.
  • Liu MA, DuMontier C, Murillo A, et al. Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies. Blood. 2019;134(4):374–382.
  • Tuchman SA, Lane A, Hornsby WE, et al. Quantitative measures of physical functioning after autologous hematopoietic stem cell transplantation in multiple myeloma: a feasibility study. Clin Lymphoma Myeloma Leuk. 2015;15(2):103–109.
  • Jones LW, Courneya KS, Vallance JK, et al. Association between exercise and quality of life in multiple myeloma cancer survivors. Support Care Cancer. 2004;12(11):780–788.
  • Craike M, Hose K, Livingston PM. Physical activity participation and barriers for people with multiple myeloma. Support Care Cancer. 2013;21(4):927–934.
  • Nicol JL, Woodrow C, Burton NW, et al. Physical activity in people with multiple myeloma: associated factors and exercise program preferences. J Clin Med. 2020;9(10):3277.
  • Adams SA, Moore CG, Cunningham JE, et al. The effect of social desirability and social approval on self-reports of physical activity. Am J Epidemiol. 2005;161(4):389–398.
  • Santa Mina D, Dolan LB, Lipton JH, et al. Exercise before, during, and after hospitalization for allogeneic hematological stem cell transplant: a feasibility randomized controlled trial. J Clin Med. 2020;9(6):1854.
  • McCourt O, Fisher A, Land J, et al. “What I wanted to do was build myself back up and prepare”: qualitative findings from the PERCEPT trial of prehabilitation during autologous stem cell transplantation in myeloma. [Manuscript submitted for publication]; 2023.
  • McCourt O, Fisher A, Land J, et al. The views and experiences of people with myeloma referred for autologous stem cell transplantation, who were approached but declined to participate in a physiotherapist-led exercise intervention trial: a qualitative study. [Manuscript submitted for publication]; 2023.
  • Moseson H, Kumar S, Juusola JL. Comparison of study samples recruited with virtual versus traditional recruitment methods. Contemp Clin Trials Commun. 2020;19:100590.