A case report of improvement on ADHD symptoms after fecal microbiota transplantation with gut microbiome profiling pre- and post-procedure

References

• Checa-Ros A, Jeréz-Calero A, Molina-Carballo A, et al. Current evidence on the role of the gut microbiome in ADHD pathophysiology and therapeutic implications. Nutrients. 2021;13(1):249.
   PubMed Web of Science ®Google Scholar
• Mohajeri MH, Fata GL, Steinert RE, et al. Relationship between the gut microbiome and brain function. Nutr Rev. 2018;76(7):481–496.
   PubMed Web of Science ®Google Scholar
• Aarts E, Ederveen THA, Naaijen J, et al. Gut microbiome in ADHD and its relation to neural reward anticipation. PLoS One. 2017;12(9):e0183509.
   PubMed Web of Science ®Google Scholar
• Jiang HY, Zhou YY, Zhou GL, et al. Gut microbiota profiles in treatment-naïve children with attention deficit hyperactivity disorder. Behav Brain Res. 2018;347:408–413.
   PubMed Web of Science ®Google Scholar
• Prehn-Kristensen A, Zimmermann A, Tittmann L, et al. Reduced microbiome alpha diversity in young patients with ADHD. PLoS One. 2018;13(7):e0200728.
   PubMed Web of Science ®Google Scholar
• Wang LJ, Yang CY, Chou WJ, et al. Gut microbiota and dietary patterns in children with attention-deficit/hyperactivity disorder. Eur Child Adolesc Psychiatry. 2020;29(3):287–297.
   PubMed Web of Science ®Google Scholar
• Wan L, Ge WR, Zhang S, et al. Case–control study of the effects of gut microbiota composition on neurotransmitter metabolic pathways in children with attention deficit hyperactivity disorder. Front Neurosci. 2020;14:1–9.
   PubMed Web of Science ®Google Scholar
• Szopinska-Tokov J, Dam S, Naaijen J, et al. Investigating the gut microbiota composition of individuals with attention-deficit/hyperactivity disorder and association with symptoms. Microorganisms. 2020;8(3):406–414.
   PubMed Web of Science ®Google Scholar
• Bull Larsen S, Mohajeri MH. The potential influence of the bacterial microbiome on the development and progression of ADHD. Nutrients. 2019;11(11):2805.
   PubMed Web of Science ®Google Scholar
• Baunwall SMD, Lee MM, Eriksen MK, et al. Faecal microbiota transplantation for recurrent Clostridioides difficile infection: an updated systematic review and meta-analysis. EClinicalMedicine. 2020;29-30:100642.
   PubMedGoogle Scholar
• Li N, Chen H, Cheng Y, et al. Fecal microbiota transplantation relieves gastrointestinal and autism symptoms by improving the gut microbiota in an open-label study. Front Cell Infect Microbiol. 2021;11:759435.
   PubMed Web of Science ®Google Scholar
• Kuai XY, Yao XH, Xu LJ, et al. Evaluation of fecal microbiota transplantation in Parkinson’s disease patients with constipation. Microb Cell Fact. 2021;20(1):98.
   PubMed Web of Science ®Google Scholar
• Park SH, Lee JH, Shin J, et al. Cognitive function improvement after fecal microbiota transplantation in Alzheimer’s dementia patient: a case report. Curr Med Res Opin. 2021;37(10):1739–1744.
   PubMed Web of Science ®Google Scholar
• Cammarota G, Ianiro G, Kelly CR, et al. International consensus conference on stool banking for faecal microbiota transplantation in clinical practice. Gut. 2019;68(12):2111–2121.
   PubMed Web of Science ®Google Scholar
• Cammarota G, Ianiro G, Tilg H, et al. European consensus conference on faecal microbiota transplantation in clinical practice. Gut. 2017;66(4):569–580.
   PubMed Web of Science ®Google Scholar
• DeFilipp Z, Bloom PP, Soto MT, et al. Drug-resistant E. coli bacteremia transmitted by fecal microbiota transplant. N Engl J Med. 2019;381(21):2043–2050.
   PubMed Web of Science ®Google Scholar
• Mullish BH, Quraishi MN, Segal JP, et al. The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridium difficile infection and other potential indications: joint british society of gastroenterology (BSG) and healthcare infection society (HIS) guidelines. J Hosp Infect. 2018;100(1):S1–S31.
   PubMed Web of Science ®Google Scholar
• Chen J, Zaman A, Ramakrishna B, et al. Stool banking for fecal microbiota transplantation: methods and operations at a large stool bank. Front Cell Infect Microbiol. 2021;11:622949.
   PubMed Web of Science ®Google Scholar
• Terveer EM, Beurden YH, Goorhuis A, et al. How to: establish and run a stool bank. Clin Microbiol Infect. 2017;23(12):924–930.
   PubMed Web of Science ®Google Scholar
• McIver LJ, Abu-Ali G, Franzosa EA, et al. bioBakery: a meta’omic analysis environment. Bioinformatics. 2018;34(7):1235–1237.
   PubMed Web of Science ®Google Scholar
• RStudio Team [Internet]. Boston (MA): RStudio: Integrated Development for R; [cited 2022 Apr 18]. Available from: http://www.rstudio.com/
   Google Scholar
• McMurdie PJ, Holmes S. Phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PLoS One. 2013;8(4):e61217.
   PubMed Web of Science ®Google Scholar
• Wickham H [Internet]. New York (NY): ggplot2: Elegant Graphics for Data Analysis; [cited 2022 Apr 18]. Available from: https://ggplot2.tidyverse.org
   Google Scholar
• Busner J, Targum SD. The clinical global impressions scale: applying a research tool in clinical practice. Psychiatry. 2007;4(7):28–37.
   PubMedGoogle Scholar
• Sukmajaya AC, Lusida MI, Setiawati Y. Systematic review of gut microbiota and attention-deficit hyperactivity disorder (ADHD). Ann Gen Psychiatry. 2021;20(1):12.
   PubMed Web of Science ®Google Scholar
• Basen M, Kurrer SE. A close look at pentose metabolism of gut bacteria. FEBS J. 2021;288(6):1804–1808.
   PubMed Web of Science ®Google Scholar
• Bollmann S, Ghisleni C, Poil S-S, et al. Developmental changes in gamma-aminobutyric acid levels in attention-deficit/hyperactivity disorder. Transl Psychiatry. 2015;5(6):e589–e589.
   PubMed Web of Science ®Google Scholar
• Nagamitsu S, Yamashita Y, Tanigawa H, et al. Upregulated GABA inhibitory function in ADHD children with child behavior checklist – dysregulation profile: 123I-iomazenil SPECT study. Front Psychiatry. 2015;6(84):84.
   PubMed Web of Science ®Google Scholar
• Murphy KR, Adler LA. Assessing attention-deficit/hyperactivity disorder in adults: focus on rating scales. J Clin Psychiatry. 2004;65(3):12–17.
   PubMed Web of Science ®Google Scholar
• Wang YP, Gorenstein C. Psychometric properties of the Beck Depression Inventory-II: a comprehensive review. Braz J Psychiatry. 2013;35(4):416–431.
   PubMed Web of Science ®Google Scholar