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Research Article

A Homeodomain Protein Binding Element in the Bone Sialoprotein Promoter is Critical for Tissue-Specific Expression in Bone

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Pages 154-160 | Published online: 06 Aug 2009

References

  • Ganss, B., Kim, R.H., and Sodek, J. (1999). Bone sialoprotein. Crit. Rev.Oral Biol. Med. 10:79–98.
  • Chen, J.K., Shapiro, H.S., Wrana, J.L., Reimers, S., Heersche, J.N., and Sodek, J. (1991). Localization of bone sialoprotein (BSP) expression to sites of mineralized tissue formation in fetal rat tissues by in situ hybridiza- tion. Matrix 11:133–143.
  • Chen, J., Shapiro, H.S., and Sodek, J. (1992). Development expression of bone sialoprotein mRNA in rat mineralized connective tissues. J. Bone Miner. Res. 7:987–997.
  • Benson, M.D., Aubin, J.E., Xiao, G., Thomas, P.E., and Franceschi, R.T. (1999). Cloning of a 2.5 kb murine bone sialoprotein promoter fragment and functional analysis of putative Osf2 binding sites. J. Bone Miner. Res. 14(3):396–405.
  • Benson, M.D., Bargeon, J.L., Xiao, G., Thomas, P.E., Kim, A., Cui, Y., and Franceschi, R.T. (2000). Identification of a homeodomain bindingelement in the bone sialoprotein gene promoter that is required for its osteoblast-selective expression. J. Biol. Chem. 275:13907–13917.
  • Morasso, M.I., Mahon, K.A., and Sargent, T.D. (1995). A Xenopus distal- less gene in transgenic mice: Conserved regulation in distal limb epidermis and other sites of epithelial-mesenchymal interaction. Proc. Natl. Acad. Sci. USA 92:3968–3972.
  • Hogan, B., Beddingon, R., Constantini, F., and Lacy, E. (1994). Manupu- lating the Mouse Embryo: A Laboratory Manual (Cold Spring Harbor Press, New York).
  • Camper, S. (1987). Research application of transgenic mice. Biotechniques 5: 638–650.
  • Frendo, J.L., Xiao, G., Fuchs, S., Franceschi, R.T., Karsenty, G., and Ducy,P. (1998). Functional hierarchy between two OSE2 elements in the con- trol of osteocalcin gene expression in vivo. J. Biol. Chem. 273:30509–30516.
  • Franz, W.M., Mueller, O.J., Fleischmann, M., Babij, P., Frey, N., Mueller, M., Besenfelder, U., Moorman, A.F., Brem, G., and Katus, H.A. (1999). The 2.3 kb smooth muscle myosin heavy chain promoter directs gene expression into the vascular system of transgenic mice and rabbits. Car- diovasc. Res. 4:1040–1048.
  • Bedalov, A., Salvatori, R., Dodig, M., Kronenberg, M.S., Kapural, B., Bogdanovic, Z., Kream, B.E., Woody, C.O., Clark, S.H., Mack, K., Rowe, D.W., and Lichtler, A.C. (1995). Regulation of Col1A1 expression in type I collagen producing tissue: Identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice. J. Bone Miner. Res. 10:1443–1451.
  • Rossert, J.A., Chen, S.S., Eberspaecher, H., Smith, C.N., and de Crombrugghe, B. (1996). Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level os- teoblast expression in transgenic mice and that binds a protein se- lectively present in osteoblasts. Proc. Natl. Acad. Sci. USA 93:1027–1031.
  • Yang, X., Ji, X., Shi, X., and Cao, X. (2000). Smad1 domains interacting with Hoxc-8 induce osteoblast differentiation. J. Biol. Chem. 275:1065–1072.
  • Goff, D.J., and Tabin, C.J. (1997). Analysis of Hoxd-13 and Hoxd-11 misexpression in chick limb buds reveals that Hox genes affect both bone condensation and growth. Development 124:627–636.
  • Satokata, I., and Maas, R. (1994). Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nat. Genet. 6:348–356.
  • Liu, Y.H., Kundu, R., Wu, L., Luo, W., Ignelzi, M.A. Jr., Snead, M.L., and Maxson, R.E., Jr. (1995). Premature suture closure and ectopic cranial bone in mice expressing Msx2 transgenes in the developing skull. Proc. Natl. Acad. Sci. USA 92:6137–6141.
  • Ryoo, H.M., Hoffmann, H.M., Beumer, T., Frenkel, B., Towler, D.A., Stein, G.S., Stein, J.L., van Wijnen, A.J., and Lian, J.B. (1997). Stage- specific expression of Dlx-5 during osteoblast differentiation: Involvement in regulation of osteocalcin gene expression. Mol. Endocrinol. 11:1681–1694.
  • Davis, A.P., and Capecchi, M.R. (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Develop- ment 120:2187–2198.
  • Towler, D.A., Rutledge, S.J., and Rodan, G.A. (1994). Msx-2/Hox 8.1: A transcriptional regulator of the rat osteocalcin promoter. Mol. Endocrinol. 8:1484–1493.
  • Acampora, D., Merlo, G.R., Paleari, L., Zerega, B., Postiglione, M.P., Mantero, S., Bober, E., Barbieri, O., Simeone, A., and Levi, G. (1999). Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development 126:3795–3809.
  • Depew, M.J., Liu, J.K., Long, J.E., Presley, R., Meneses, J.J., Pedersen, R.A., and Rubenstein, J.L. (1999). Dlx5 regulates regional development of the branchial arches and sensory capsules. Development 126:3831–3846.
  • Newberry, E.P., Latifi, T., and Towler, D.A. (1998). Reciprocal regulation of osteocalcin transcription by the homeodomain proteins Msx2 and Dlx5. Biochemistry 37:16360–16368.
  • Ducy, P., and Karsenty, G. (1995). Two distinct osteoblast-specific cis- acting elements control expression of a mouse osteocalcin gene. Mol. Cell Biol. 15:1858–1869.
  • Ducy, P., Zhang, R., Geoffroy, V., Ridall, A.L., and Karsenty, G. (1997). Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89:747–754.
  • Kern, B., Shen, J., Starbuck, M., and Karsenty, G. (2001). Cbfa1 con- tributes to the osteoblast-specific expression of type I collagen genes. J. Biol. Chem. 276:7101–7107.

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