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Original

Versican in Health and Disease

Pages 230-234 | Published online: 06 Aug 2009

REFERENCES

  • Iozzo R.V. Matrix proteoglycans: from molecular design to cellular function. Annu. Rev. Biochem. 1998; 67: 609–652
  • Rahmani M., Wong B.W., Ang L., Cheung C.C., Carthy J.M., Walinski H., McManus B.M. Versican: signaling to transcriptional control pathways. Can. J. Physiol. Pharmacol. 2006; 84: 77–92
  • Wight T.N. Versican: a versatile extracellular matrix proteoglycan in cell biology. Curr. Opin. Cell Biol. 2002; 14: 617–623
  • Naso M.F., Zimmermann D.R., Iozzo R.V. Characterization of the complete genomic structure of the human versican gene and functional analysis of its promoter. J. Biol. Chem. 1994; 269: 32999–33008
  • Schonherr E., Kinsella M.G., Wight T.N. Genistein selectively inhibits platelet-derived growth factor-stimulated versican biosynthesis in monkey arterial smooth muscle cells. Arch. Biochem. Biophys. 1997; 339: 353–361
  • Shimizu-Hirota R., Sasamura H., Mifune M., Nakaya H., Kuroda M., Hayashi M., Saruta T. Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors. J. Am. Soc. Nephrol. 2001; 12: 2609–2615
  • Rahmani M., Read J.T., Carthy J.M., McDonald P.C., Wong B.W., Esfandiarei M., Si X., Luo H., Rennie P.S., McManus B.M. Regulation of the versican promoter by the beta-catenin-T-cell factor complex in vascular smooth muscle cells. J. Biol. Chem. 2005; 280: 13019–13028
  • Yoon H., Liyanarachchi S., Wright F.A., Davuluri R., Lockman J.C., Chapelle A., Pellegata N.S. Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53. Proc. Natl. Acad. Sci. USA 2002; 99: 15632–15637
  • Willert J., Epping M., Pollack J.R., Brown P.O., Nusse R. A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev. Biol. 2002; 2: 8, doi: 10.1186/ 1471–213X-2-8
  • Fedtsova N., Perris R., Turner E.E. Sonic hedgehog regulates the position of the trigeminal ganglia. Dev. Biol. 2003; 261: 456–469
  • Theocharis A.D., Tsolakis I., Tzanakakis G.N., Karamanos N.K. Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression. Adv. Pharmacol. 2006; 53: 281–295
  • Wegrowski Y., Maquart F.X. Chondroitin sulfate proteoglycans in tumor progression. Adv. Pharmacol. 2006; 53: 297–321
  • Mullor J.L., Sanchez P., Altaba A.R. Pathways and consequences: hedgehog signaling in human disease. Trends Cell Biol. 2002; 12: 562–569
  • Wight T.N., Merrilees M.J. Proteoglycans in atherosclerosis and restenosis: key roles for versican. Circ. Res. 2004; 94: 1158–1167
  • Wu Y.J., Lapierre D., Wu J., Yee A.J., Yang B.B. The interaction of versican with its binding partners. Cell Res. 2005; 15: 483–494
  • Theocharis A.D., Tsolakis I., Hjerpe A., Karamanos N.K. Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V0. Atherosclerosis 2001; 154: 367–376
  • Theocharis A.D., Tsolakis I., Hjerpe A., Karamanos N.K. Versican undergoes specific alterations in the fine molecular structure and organization in human aneurysmal abdominal aortas. Biomed. Chromatogr. 2003; 17: 411–416
  • Ruigrok Y.M., Rinkel G.J., Wijmenga C. The versican gene and the risk of intracranial aneurysms. Stroke 2006; 37: 2372–2374
  • Theocharis A.D., Theocharis D.A., DeLuca G., Hjerpe A., Karamanos N.K. Compositional and structural alterations of chondroitin and dermatan sulfates during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aorta. Biochimie 2002; 84: 667–674
  • McGee M., Wagner W.D. Chondroitin sulfate anticoagulant activity is linked to water transfer: relevance to proteoglycan structure in atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2003; 23: 1921–1927
  • Zheng P.S., Vais D., Lapierre D., Liang Y.Y., Lee V., Yang B.L., Yang B.B. PG-M/versican binds to P-selectin glycoprotein ligand-1 and mediates leukocyte aggregation. J. Cell. Sci. 2004; 117: 5887–5895
  • Merrilees M.J., Lemire J.M., Fischer J.W., Kinsella M.G., Braun K.R., Clowes A.W., Wight T.N. Retrovirally mediated overexpression of versican V3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injury. Circ. Res. 2002; 90: 481–487
  • Huang R., Merrilees M.J., Braun K., Beaumont B., Lemire J., Clowes A.W., Hinek A., Wight T.N. Inhibition of versican synthesis by antisense alters smooth muscle cell phenotype and induces elastic fiber formation in vitro and in neointima after vessel injury. Circ. Res. 2006; 98: 370–377
  • Tsara M.E., Theocharis A.D., Theocharis D.A. Compositional and structural alterations of proteoglycans in human rectum carcinoma with special reference to versican and decorin. Anticancer Res 2002; 22: 2893–2898
  • Theocharis A.D. Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorin. Biochim. Biophys. Acta 2002; 1588: 165–172
  • Theocharis A.D., Vynios D.H., Papageorgakopoulou N., Skandalis S.S., Theocharis D.A. Altered content, composition and structure of glycosaminoglycans and proteoglycans in gastric carcinoma. Int. J. Biochem. Cell Biol. 2003; 35: 376–390
  • Skandalis S.S., Theocharis A.D., Theocharis D.A., Papadas T., Vynios D.H., Papageorgakopoulou N. Matrix proteoglycans are markedly affected in advanced laryngeal squamous cell carcinoma. Biochim. Biophys. Acta 2004; 1689: 152–161
  • Skandalis S.S., Theocharis A.D., Papageorgakopoulou N., Vynios D.H., Theocharis D.A. The increased accumulation of structurally modified versican and decorin is related with the progression of laryngeal cancer. Biochimie 2006; 88: 1135–1143
  • Labropoulou V.T., Theocharis A.D., Ravazoula P., Perimenis P., Hjerpe A., Karamanos N.K., Kalofonos H.P. Versican but not decorin accumulation is related to metastatic potential and neovascularization in testicular germ cell tumors. Histopathology 2006; 49: 582–593
  • Skandalis S.S., Kletsas D., Kyriakopoulou D., Stavropoulos M., Theocharis D. The greatly increased amounts of accumulated versican and decorin with specific post-translational modifications may be closely associated with the malignant phenotype of pancreatic cancer. Biochim. Biophys. Acta 2006; 1760: 1217–1225
  • Sheng W., Wang G., LaPierre D.P., Wen J., Deng Z., Wong C.K.A., Lee D.Y., Yang B.B. Versican mediates mesenchymal-epithelial transition. Mol. Biol. Cell 2006; 17: 2009–2020
  • Sheng W., Dong H., Lee D.Y., Lu W.Y., Yang B.B. Versican modulates gap junction intercellular communication. J. Cell. Physiol. 2007; 211: 213–219
  • Sheng W., Wang G.Z., Wang Y.L., Liang J., Wen J., Zheng P.S., Wu Y., Lee V., Slingerland J., Dumont D., Yang B.B. The roles of versican V1 and V2 isoforms in cell proliferation and apoptosis. Mol. Biol. Cell 2005; 16: 1330–1340
  • La Pierre D.P., Lee D.Y., Li S.Z., Xie Y.Z., Zhong L., Sheng W., Deng Z., Yang B.B. The ability of versican to simultaneously cause apoptotic resistance and sensitivity. Cancer Res. 2007; 67: 4742–4750
  • Zhang Y., Cao L., Yang B.L., Yang B.B. The G3 domain of versican enhances cell proliferation via epidermal growth factor-like motifs. J. Biol. Chem. 1998; 273: 21342–21351
  • Zheng P.S., Wen J., Ang L.C., Sheng W., Vilora-Petit A., Wang Y., Wu Y., Kerbel R.S., Yang B.B. Versican/PG-M G3 domain promotes tumor growth and angiogenesis. FASEB J. 2004; 18: 754–756
  • Wu Y., Zhang Y., Cao L., Chen L., Lee V., Zheng P.S., Kiani C., Adams M.E., Ang L.C., Paiwand F., Yang B.B. Identification of the motif in versican G3 domain that plays a dominant-negative effect on astrocytoma cell proliferation through inhibiting versican secretion and binding. J. Biol. Chem. 2001; 276: 14178–14186
  • Wu Y., Chen L., Zheng P.S., Yang B.B. Beta 1-Integrin-mediated glioma cell adhesion and free radical-induced apoptosis are regulated by binding to a C-terminal domain of PG-M/versican. J. Biol. Chem. 2002; 277: 12294–12301
  • Yang B.L., Zhang Y., Cao L., Yang B.B. Cell adhesion and proliferation mediated through the G1 domain of versican. J. Cell. Biochem. 1999; 72: 210–220
  • Cattaruzza S., Schiappacassi M., Ljungberg-Rose A., Spessotto P., Perissinotto D., Morgelin M., Mucignat M.T., Colombatti A., Periis R. Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro. J. Biol. Chem. 2002; 277: 47626–47635
  • Miguel-Serra L., Serra M., Hernandez D., Domenzain C., Docampo M.J., Rabanal R.M., de Torres I., Wight T.N., Fabra A., Bassols A. V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis. Lab. Invest. 2006; 86: 889–901
  • Cattaruzza S., Perris R. Proteoglycan control of cell movement during wound healing and cancer spreading. Matrix Biol 2005; 24: 400–417
  • Wu Y., Sheng W., Chen L., Dong H., Lee V., Lu F., Wong G.S., Lu W.Y., Yang B.B. Versican V1 isoform induces neuronal differentiation and promotes neurite outgrowth. Mol. Biol. Cell 2004; 15: 2093–2104
  • Xiang Y.Y., Dong H., Wan Y., Li J., Yee A., Yang B.B., Lu W.Y. Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor. J. Biol. Chem. 2006; 281: 19358–19368

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