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Original

Molecular Profile of the BCL2 Family of the Apoptosis Related Genes in Breast Cancer Cells after Treatment with Cytotoxic/Cytostatic Drugs

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Pages 261-264 | Published online: 06 Aug 2009

REFERENCES

  • Thomadaki H, Scorilas A. BCL2 family of apoptosis-related genes: functions and clinical implications in cancer. Crit. Rev. Clin. Lab. Sci. 2006; 43: 1–67
  • Scorilas A., Kyriakopoulou L., Yousef GM., Ashworth L., Kwamie A., Diamandis E.P. Molecular cloning, physical mapping and expression analysis of a novel gene, BCL2L12, encoding for a proline-rich protein with a highly conserved BH2 domain of the Bcl-2 family. Genomics 2001; 72: 217–221
  • Thomadaki H., Talieri M., Scorilas A. Prognostic value of the apoptosis related genes. BCL2 and BCL2L12 in breast cancer. Cancer Lett. 2007; 247(1)48–55
  • Mathioudaki K., Scorilas A., Papadokostopoulou A., Xynopoulos D., Arnogianaki N., Agnanti N., Talieri M. Expression analysis of BCL2L12, a new member of apoptosis-related genes, in colon cancer. Biol Chem. 2004; 385(9)779–783
  • Floros K.V., Thomadaki H., Lallas G., Katsaros N., Talieri M., Scorilas A. Cisplatin-induced apoptosis in HL-60 human promyelocytic leukemia cells: differential expression of BCL2 and novel apoptosis-related gene BCL2L12. Ann NY Acad Sci. 2003; 1010: 153–158
  • Lloyd D.R., Hanawalt P.C. p53-dependent global genomic repair of benzo-[a]pyrene-7,8-diol-9,10-epoxide adducts in human cells. Cancer Res. 2000; 60: 517–521
  • Lin C.C., Tsai Y.L., Huang M.T., Lu Y.P., Ho C.T., Tseng S.F., Teng S.C. Inhibition of estradiol-induced mammary proliferation by dibenzoylmethane through the E2-ER-ERE-dependent pathway. Carcinogenesis 2006; 27: 131–136
  • Meinking T.L., Serrano L., Hard B., Entzel P., Lemard G., Rivera E., Villar M.E. Comparative in vitro pediculicidal efficacy of treatments in a resistant head lice population in the United States. Arch. Dermatol. 2002; 38: 220–224
  • Kalantzi O.I., Hewitt R., Ford K.J., Cooper L., Alcock R.E., Thomas G.O., Morris J.A., McMillan T.J., Jones K.C., Martin F.L. Low dose induction of micronuclei by lindane. Carcinogenesis 2004; 25: 613–622
  • Wittmann S., Bali P., Donapaty S., Nimmanapalli R., Guo F., Yamaguchi H., Huang M., Jove R., Wang H.G., Bhalla K. Flavopiridol downregulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis. Cancer Res. 2003; 63: 93–99
  • Tong A.W., Papayoti M.H., Netto G., Armstrong D.T., Ordonez G., Lawson J.M., Stone M.J. Growth-inhibitory effects of CD40 ligand (CD154) and its endogenous expression in human breast cancer. Clin. Cancer Res. 2001; 7: 691–703
  • Kilgore M.W., Tate P.L., Pai S., Sengoku E., Price T.M. MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response. Mol. Cell. Endocrinol. 1997; 129: 229–235
  • Kuo P.L., Hsu Y.L., Lin T.C., Tzeng W.S., Chen Y.Y., Lin C.C. Rugosin E, an ellagitannin, inhibits MDA-MB-231 human breast cancer cell proliferation and induces apoptosis by inhibiting nuclear factor-kappaB signaling pathway. Cancer Lett. 2007; 248: 280–291
  • Poma P., Notarbartolo M., Labbozzetta M., Maurici A., Carina V., Alaimo A., Rizzi M., Simoni D., D’Alessandro N. The antitumor activities of curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis. Int. J. Mol. Med. 2007; 20: 329–335
  • Ramachandran C., Rodriguez S., Ramachandran R., Raveendran Nair P.K., Fonseca H., Khatib Z., Escalon E., Melnick S.J. Expression profiles of apoptotic genes induced by curcumin in human breast cancer and mammary epithelial cell lines. Anticancer Res. 2005; 25: 3293–3302
  • Siethoff C., Orth M., Ortling A., Brendel E., Wagner-Redeker W. Simultaneous determination of capecitabine and its metabolite 5-fluorouracil by column switching and liquid chromatographic/tandem mass spectrometry. J. Mass Spectrom. 2004; 39: 884–889
  • Hernández-Vargas H., Ballestar E., Carmona-Saez P., von Kobbe C., Bañón-Rodríguez I., Esteller M., Moreno-Bueno G., Palacios J. Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53. Int. J. Cancer 2006; 119: 1164–1175
  • Dave B., Eason R.R., Till S.R., Geng Y., Velarde M.C., Badger T.M., Simmen R.C. The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN. Carcinogenesis 2005; 26: 1793–1803
  • Sarkar F.H., Li Y. Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer Metastasis Rev. 2002; 21: 265–280
  • Lamartiniere C.A., Moore J.B., Brown N.M., Thompson R., Hardin M.J., Barnes S. Genistein suppresses mammary cancer in rats. Carcinogenesis 1995; 16: 2833–2840
  • Somaï S., Gompel A., Rostène W., Forgez P. Neurotensin counteracts apoptosis in breast cancer cells. Biochem. Biophys. Res. Commun. 2002; 295: 482–488
  • Kasukabe T., Okabe-Kado J., Kato N., Sassa T., Honma Y. Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts. Breast Cancer Res. 2005; 7: R1097–R1110
  • Fenig E., Livnat T., Sharkon-Polak S., Wasserman L., Beery E., Lilling G., Yahalom J., Wieder R., Nordenberg J. Basic fibroblast growth factor potentiates cisplatinum-induced cytotoxicity in MCF-7 human breast cancer cells. J. Cancer. Res. Clin. Oncol. 1999; 125: 556–562
  • Diel P., Smolnikar K., Michna H. The pure antiestrogen ICI 182780 is more effective in the induction of apoptosis and down regulation of BCL2 than tamoxifen in MCF-7 cells. Breast Cancer Res. Treat. 1999; 58: 87–97
  • Leung L.K., Wang T.T. Differential effects of chemotherapeutic agents on the BCL2/Bax apoptosis pathway in human breast cancer cell line MCF-7. Breast Cancer Res. Treat. 1999; 55: 73–83
  • Thomadaki H., Scorilas A. Breast cancer cells response to the antineoplastic agents cisplatin, carboplatin, and doxorubicin at the mRNA expression levels of distinct apoptosis-related genes, including the new member, BCL2L12. Ann. NY Acad. Sci. 2007; 1095: 35–44
  • Liu J.W., Chandra D., Rudd M.D., Butler A.P., Pallotta V., Brown D., Coffer P.J., Tang D.G. Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. Oncogene 2005; 24: 2020–2031
  • Thomadaki H., Talieri M., Scorilas A. Treatment of MCF-7 cells with taxol and etoposide induces distinct alterations in the expression of apoptosis-related genes BCL2, BCL2L12, BAX, CASPASE-9 and FAS. Biol. Chem. 2006; 387: 1081–1086
  • Sunters A., Fernández de Mattos S., Stahl M., Brosens J.J., Zoumpoulidou G., Saunders C.A., Coffer P.J., Medema R.H., Coombes R.C., Lam E.W. FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J. Biol. Chem. 2003; 278: 49795–49805
  • Beck M.T., Peirce S.K., Chen W.Y. Regulation of BCL2 gene expression in human breast cancer cells by prolactin and its antagonist, hPRL-G129R. Oncogene 2002; 21: 5047–5055
  • Wang T.T., Phang J.M. Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7. Cancer Res. 1995; 55: 2487–2490
  • Gompel A., Somaï S., Chaouat M., Kazem A., Kloosterboer H.J., Beusman I., Forgez P., Mimoun M., Rostène W. Hormonal regulation of apoptosis in breast cells and tissues. Steroids 2000; 65: 593–598
  • Frasor J., Danes J.M., Komm B., Chang K.C., Lyttle C.R., Katzenellenbogen B.S. Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 2003; 144: 4562–4574
  • Mandal M., Kumar R. BCL2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. Cell Growth Differ. 1996; 7: 311–318

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