236
Views
17
CrossRef citations to date
0
Altmetric
Original

Tissue-Specific shRNA Delivery: A Novel Approach for Gene Therapy in Cancer

, , , , , , , , , & show all
Pages 265-269 | Published online: 06 Aug 2009

REFERENCES

  • Matzke M.A., Birchler J.A. RNAi-mediated pathways in the nucleus. Nat Rev Genet. 2005; 6: 24–35
  • Napoli C., Lemieux C., Jorgensen R. Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 1990; 2: 279–289
  • Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806–811
  • Kennerdell J.R., Carthew R.W. Heritable gene silencing in Drosophila using double-stranded RNA. Nat Biotechnol. 2000; 18: 896–898
  • Aigner A. Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo. J. Biomed. Biotechnol. 2006; 71659
  • Grimm D., Streetz K.L., Jopling C.L., Storm T.A., Pandey K., Davis C.R., et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006; 441: 537–541
  • Turley E.A. The Biology of Hyaluronan. , et al. J.Wiley & Sons, Ltd., Chichester, U.K. 1989; 121
  • Toole B.P. Hyaluronan: from extracellular glue to pericellular cue. Nat. Rev. Cancer 2004; 4: 528–539
  • Ghatak S., Misra S., Toole B.P. Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J. Biol. Chem. 2002; 77: 38013–38020
  • Knudson C.B., Knudson W. Hyaluronan-binding proteins in development, tissue homeostasis, and disease. FASEB. J. 1993; 7: 1233–1241
  • Entwistle J., Hall C.L., Turley E.A. HA receptors: regulators of signalling to the cytoskeleton. J. Cell. Biochem. 1996; 61: 569–577
  • Campbell P., Laurent T.C., Roden L. Assay and properties of N-acetylglucosamine-6-phosphate deacetylase from rat liver. Anal. Biochem. 1987; 166: 134–141
  • Hua Q., Knudson C.B., Knudson W. Internalization of hyaluronan by chondrocytes occurs via receptor-mediated endocytosis. J. Cell. Sci. 1993; 106: 365–375
  • Ponta H., Sherman L., Herrlich P.A. CD44: from adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell. Biol. 2003; 4: 33–45
  • Nakazawa H., Yoshihara S., Kudo D., Morohashi H., Kakizaki I., Kon A., et al. 4-methylumbelliferone, a hyaluronan synthase suppressor, enhances the anticancer activity of gemcitabine in human pancreatic cancer cells. Cancer Chemother. Pharmacol. 2006; 57: 165–170
  • Ghatak S., Misra S., Toole B.P. Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells. J. Biol. Chem. 2005; 280: 8875–8883
  • Misra S., Toole B.P., Ghatak S. Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells. J. Biol. Chem. 2006; 281: 34936–34941
  • Mike S., Harrison C., Coles B., Staffurth J., Wilt T.J., Mason M.D. Chemotherapy for hormone-refractory prostate cancer. Cochrane Database Syst. Rev. 2006; CD005247
  • Welsh C.F., Zhu D., Bourguignon L.Y. Interaction of CD44 variant isoforms with hyaluronic acid and the cytoskeleton in human prostate cancer cells. J. Cell. Physiol. 1995; 164: 605–612
  • Omara-Opyene A.L., Qiu J., Shah G.V., Iczkowski K.A. Prostate cancer invasion is influenced more by expression of a CD44 isoform including variant 9 than by Muc18. Lab. Invest. 2004; 84: 894–907
  • Gupta R.A., Dubois R.N. Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2. Nat. Rev. Cancer 2001; 1: 11–21
  • Dohadwala M., Luo J., Zhu L., Lin Y., Dougherty G.J., Sharma S., et al. Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44. J. Biol. Chem. 2001; 276: 20809–20812
  • Reeder J.A., Gotley D.C., Walsh M.D., Fawcett J., Antalis T.M. Expression of antisense CD44 variant 6 inhibits colorectal tumor metastasis and tumor growth in a wound environment. Cancer Res. 1998; 58: 3719–3726
  • Ruponen M., Honkakoski P., Tammi M., Urtti A. Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer. J. Gene. Med. 2004; 6: 405–414
  • Ruponen M., Ronkko S., Honkakoski P., Pelkonen J., Tammi M., Urtti A. Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes. J. Biol. Chem. 2001; 276: 33875–33880
  • Eliaz R.E., Szoka F.C., Jr. Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells. Cancer Res. 2001; 61: 2592–2601
  • Haapala J., Arokoski J.P., Ronkko S., Agren U., Kosma V.M., Lohmander L.S., et al. Decline after immobilisation and recovery after remobilisation of synovial fluid IL1, TIMP, and chondroitin sulphate levels in young beagle dogs. Ann. Rheum. Dis. 2001; 60: 55–60
  • Ventura A., Meissner A., Dillon C.P., McManus M., Sharp P.A., Van Parijs L., et al. Cre-lox-regulated conditional RNA interference from transgenes. Proc. Natl. Acad. Sci. USA 2004; 101: 10380–10385
  • Moser A.R., Pitot H.C., Dove W.F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990; 247: 322–324

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.