Co-culture with infrapatellar fat pad differentially stimulates proteoglycan synthesis and accumulation in cartilage and meniscus tissues

References

• Teichtahl AJ, Wulidasari E, Brady SR, Wang Y, Wluka AE, Ding C, Giles GG, Cicuttini FM. A large infrapatellar fat pad protects against knee pain and lateral tibial cartilage volume loss. Arthritis Res Ther 2015;17:318.
   PubMed Web of Science ®Google Scholar
• Han W, Cai S, Liu Z, Jin X, Wang X, Antony B, Cao Y, Aitken D, Cicuttini F, Jones G, Ding C. Infrapatellar fat pad in the knee: is local fat good or bad for knee osteoarthritis? Arthritis Res. Ther. 2014;16(4):R145.
   Google Scholar
• Cai J, Xu J, Wang K, Zheng S, He F, Huan S, Xu S, Zhang H, Laslett L, Ding C. Association between infrapatellar fat pad volume and knee structural changes in patients with knee osteoarthritis. J Rheumatol 2015;42(10):1878–1884.
   PubMed Web of Science ®Google Scholar
• Chuckpaiwong B, Charles HC, Kraus VB, Guilak F, Nunley JA. Age-associated increases in the size of the infrapatellar fat pad in knee osteoarthritis as measured by 3T MRI. J Orthopaedic Res: Off Publ Orthopaedic Res Soc 2010;28(9):1149–1154.
   PubMed Web of Science ®Google Scholar
• Cowan SM, Hart HF, Warden SJ, Crossley KM. Infrapatellar fat pad volume is greater in individuals with patellofemoral joint osteoarthritis and associated with pain. Rheumatol Int 2015;35(8):1439–1442.
   PubMed Web of Science ®Google Scholar
• Poole AR. Osteoarthritis as a whole joint disease. HSS J: Musculoskeletal J Hosp Spec Surg 2012;8(1):4–6.
   PubMedGoogle Scholar
• Loeser RF, Goldring SR, Scanzello CR, Goldring MB. Osteoarthritis: a disease of the joint as an organ. Arthritis Rheumatism 2012;64(6):1697–1707.
   PubMed Web of Science ®Google Scholar
• Steinberg JJ, Sledge CB. Synovial factors and chondrocyte-mediated breakdown of cartilage: inhibition by hydrocortisone. J Orthopaedic Res: Off Publ Orthopaedic Res Soc 1983;1(1):13–21.
   PubMedGoogle Scholar
• Beekhuizen M, Bastiaansen-Jenniskens YM, Koevoet W, Saris DB, Dhert WJ, Creemers LB, van Osch GJ. Osteoarthritic synovial tissue inhibition of proteoglycan production in human osteoarthritic knee cartilage: establishment and characterization of a long-term cartilage-synovium coculture. Arthritis Rheumatism 2011;63(7):1918–1927.
   PubMed Web of Science ®Google Scholar
• Steinberg JJ, Tsukamoto S, Sledge CB. Breakdown of cartilage proteoglycan in a tissue culture model of rheumatoid arthritis. Biochimica et biophysica Acta 1983;757(1):47–58.
   PubMed Web of Science ®Google Scholar
• Patwari P, Lin SN, Kurz B, Cole AA, Kumar S, Grodzinsky AJ. Potent inhibition of cartilage biosynthesis by coincubation with joint capsule through an IL-1-independent pathway. Scand J Med Sci Sports 2009;19(4):528–535.
   PubMed Web of Science ®Google Scholar
• Vankemmelbeke MN, Ilic MZ, Handley CJ, Knight CG, Buttle DJ. Coincubation of bovine synovial or capsular tissue with cartilage generates a soluble “Aggrecanase” activity. Biochem Biophys Res Commun 1999;255(3):686–691.
   PubMed Web of Science ®Google Scholar
• Gregg AJ, Fortier LA, Mohammed HO, Mayr KG, Miller BJ, Haupt JL. Assessment of the catabolic effects of interleukin-1beta on proteoglycan metabolism in equine cartilage cocultured with synoviocytes. Am J Vet Res 2006;67(6):957–962.
   PubMed Web of Science ®Google Scholar
• Lee CM, Kisiday JD, McIlwraith CW, Grodzinsky AJ, Frisbie DD. Synoviocytes protect cartilage from the effects of injury in vitro. BMC Musculoskeletal Disord 2013;14:54.
   PubMed Web of Science ®Google Scholar
• Ioan-Facsinay A, Kloppenburg M. An emerging player in knee osteoarthritis: the infrapatellar fat pad. Arthritis Res Ther 2013;15(6):225.
   PubMed Web of Science ®Google Scholar
• Presle N, Pottie P, Dumond H, Guillaume C, Lapicque F, Pallu S, Mainard D, Netter P, Terlain B. Differential distribution of adipokines between serum and synovial fluid in patients with osteoarthritis. Contribution of joint tissues to their articular production. Osteoarthritis Cartilage 2006;14:690–695.
   PubMed Web of Science ®Google Scholar
• Chen W-P, Bao J-P, Feng J, Hu P-F, Shi Z-L, Wu L-D. Increased serum concentrations of visfatin and its production by different joint tissues in patients with osteoarthritis. Clin Chem Lab Med 2010;48:1141–1145.
   PubMed Web of Science ®Google Scholar
• Distel E, Cadoudal T, Durant S, Poignard A, Chevalier X, Benelli C. The infrapatellar fat pad in knee osteoarthritis: an important source of interleukin-6 and its soluble receptor. Arthritis Rheumatism 2009;60(11):3374–3377.
   PubMed Web of Science ®Google Scholar
• Klein-Wieringa IR, Kloppenburg M, Bastiaansen-Jenniskens YM, Yusuf E, Kwekkeboom JC, El-Bannoudi H, Nelissen RG, Zuurmond A, Stojanovic-Susulic V, Van Osch GJ, Toes RE, Ioan-Facsinay A. The infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype. Ann Rheumatic Dis 2011;70(5):851–857.
   PubMed Web of Science ®Google Scholar
• Eymard F, Pigenet A, Citadelle D, Flouzat-Lachaniette CH, Poignard A, Benelli C, Berenbaum F, Chevalier X, Houard X. Induction of an inflammatory and prodegradative phenotype in autologous fibroblast-like synoviocytes by the infrapatellar fat pad from patients with knee osteoarthritis. Arthritis Rheumatol (Hoboken, NJ) 2014;66(8):2165–2174.
   PubMed Web of Science ®Google Scholar
• Hui W, Litherland GJ, Elias MS, Kitson GI, Cawston TE, Rowan AD, Young DA. Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases. Ann Rheumatic Dis 2012;71(3):455–462.
   PubMed Web of Science ®Google Scholar
• Bastiaansen-Jenniskens YM, Wei W, Feijt C, Waarsing JH, Verhaar JA, Zuurmond AM, Hanemaaijer R, Stoop R, van Osch GJ. Stimulation of fibrotic processes by the infrapatellar fat pad in cultured synoviocytes from patients with osteoarthritis: a possible role for prostaglandin f2alpha. Arthritis Rheumatism 2013;65(8):2070–2080.
   PubMed Web of Science ®Google Scholar
• Sun Y, Mauerhan DR, Honeycutt PR, Kneisl JS, Norton JH, Hanley EN, Jr, Gruber HE. Analysis of meniscal degeneration and meniscal gene expression. BMC Musculoskeletal Disord 2010;11:19.
   PubMed Web of Science ®Google Scholar
• Imler SM, Doshi AN, Levenston ME. Combined effects of growth factors and static mechanical compression on meniscus explant biosynthesis. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc 2004;12(9):736–744.
   PubMed Web of Science ®Google Scholar
• Wilson CG, Palmer AW, Zuo F, Eugui E, Wilson S, Mackenzie R, Sandy JD, Levenston ME. Selective and non-selective metalloproteinase inhibitors reduce IL-1-induced cartilage degradation and loss of mechanical properties. Matrix Biol 2007;26(4):259–268.
   PubMed Web of Science ®Google Scholar
• Wilson CG, Vanderploeg EJ, Zuo F, Sandy JD, Levenston ME. Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. Arthritis Res Ther 2009;11(6):R173.
   PubMed Web of Science ®Google Scholar
• Wilson CG, Nishimuta JF, Levenston ME. Chondrocytes and meniscal fibrochondrocytes differentially process aggrecan during de novo extracellular matrix assembly. Tissue Eng Part A 2009;15(7):1513–1522.
   PubMed Web of Science ®Google Scholar
• Palmer AW, Wilson CG, Baum EJ, Levenston ME. Composition-function relationships during IL-1-induced cartilage degradation and recovery. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc 2009;17(8):1029–1039.
   PubMed Web of Science ®Google Scholar
• Nishimuta JF, Levenston ME. Response of cartilage and meniscus tissue explants to in vitro compressive overload. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc 2012;20(5):422–429.
   PubMed Web of Science ®Google Scholar
• Nishimuta JF, Levenston ME. Meniscus is more susceptible than cartilage to catabolic and anti-anabolic effects of adipokines. Osteoarthritis Cartilage/OARS, Osteoarthritis Res Soc 2015;23(9):1551–1562.
   PubMed Web of Science ®Google Scholar
• Ling CH, Lai JH, Wong IJ, Levenston ME. Bovine meniscal tissue exhibits age- and interleukin-1 dose-dependent degradation patterns and composition-function relationships. J Orthopaedic Res: Off Publ Orthopaedic Res Soc 2016;34(5):801–811.
   PubMed Web of Science ®Google Scholar
• Farndale RW, Buttle DJ, Barrett AJ. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochimica et biophysica acta 1986;883:173–177.
   PubMed Web of Science ®Google Scholar
• Weinberg J, Fermor B, Guilak F. Nitric oxide synthase and cyclooxygenase interactions in cartilage and meniscus: relationships to joint physiology, arthritis, and tissue repair. Sub-Cell Biochem 2007;42:31–62.
   PubMedGoogle Scholar
• Amin AR, Abramson SB. The role of nitric oxide in articular cartilage breakdown in osteoarthritis. Curr Opin Rheumatol 1998;10:263–268.
   PubMedGoogle Scholar
• Hensley K, Mou S, Pye QN. Nitrite determination by colorimetric and fluorometric griess diazotization assays. In: Hensley K, Floyd R, eds. Methods in Pharmacology and Toxicology: Methods in Biological Oxidative Stress Totowa, NJ: Humana Press; 2003. pp. 185–193.
   Google Scholar
• Manicourt DH, Lefebvre V. An assay for matrix metalloproteinases and other proteases acting on proteoglycans, casein, or gelatin. Anal Biochem 1993;215:171–179.
   PubMed Web of Science ®Google Scholar
• Nishimuta JF. Degradation of cartilage and meniscus tissues: an in vitro investigation in osteoarthritis development. Stanford, CA: Stanford University; 2013.
   Google Scholar
• Steinhagen J, Bruns J, Niggemeyer O, Fuerst M, Rüther W, Schünke M, Kurz B. Perfusion culture system: Synovial fibroblasts modulate articular chondrocyte matrix synthesis in vitro. Tissue Cell 2010;42(3):151–157.
   PubMed Web of Science ®Google Scholar