References
- Fourlanos S, Narendran P, Byrnes GB, Colman PG, Harrison LC. 2004. Insulin resistance is a risk factor for progression to type 1 diabetes. Diabetologia. 47(10):1661–1667. doi:https://doi.org/10.1007/s00125-004-1507-3.
- de Vos P, Faas MM, Strand B, Calafiore R. 2006. Alginate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials. 27(32):5603–5617. doi:https://doi.org/10.1016/j.biomaterials.2006.07.010.
- Llacua LA, Faas MM, de Vos P. 2018. Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets. Diabetologia. 61(6):1261–1272. doi:https://doi.org/10.1007/s00125-017-4524-8.
- Puls TJ, Tan X, Whittington CF, Voytik-Harbin SL, Samant R. 2017. 3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT. PLoS One. 12(11):0188870. doi:https://doi.org/10.1371/journal.pone.0188870.
- Llacua LA, Hoek A, de Haan BJ, de Vos P. 2018. Collagen type VI interaction improves human islet survival in immunoisolating microcapsules for treatment of diabetes. Islets. 10(2):60–68. doi:https://doi.org/10.1080/19382014.2017.1420449.
- Riopel M, Stuart W, Wang R. 2013. Fibrin improves beta (INS-1) cell function, proliferation and survival through integrin alphavbeta3. Acta Biomater. 9(9):8140–8148. doi:https://doi.org/10.1016/j.actbio.2013.05.035.
- Kaido T, Yebra M, Cirulli V, Montgomery AM. 2004. Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1. J Biol Chem. 279(51):53762–53769. doi:https://doi.org/10.1074/jbc.M411202200.
- Yang J, Sun Y, Liu X, Xu F, Liu W, Hayashi T, Imamura Y, Mizuno K, Hattori S, Tanaka K, Fujisaki H, Tashiro SI, Onodera S, Ikejima T. 2019. Silibinin’s regulation of proliferation and collagen gene expressions of rat pancreatic beta-cells cultured on types I and V collagen involves beta-catenin nuclear translocation. Connect Tissue Res. 60(5):463–476. doi:https://doi.org/10.1080/03008207.2019.1593393.
- Michalski D, Spielvogel E, Puchta J, Reimann W, Barthel H, Nitzsche B, Mages B, Jager C, Martens H, Horn AKE, Schob S, Hartig W. 2020. Increased immunosignals of collagen IV and fibronectin indicate ischemic consequences for the neurovascular matrix adhesion zone in various animal models and human stroke tissue. Front Physiol. 11:575598. doi:https://doi.org/10.3389/fphys.2020.575598.
- Chakraborty S, Hong W. 2018. Linking extracellular matrix agrin to the hippo pathway in liver cancer and beyond. Cancers (Basel). 10(2):423. doi:https://doi.org/10.3390/cancers10020045.
- Lu L, Finegold MJ, Johnson RL. 2018. Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration. Exp Mol Med. 50(1):423. doi:https://doi.org/10.1038/emm.2017.205.
- Mohajan S, Jaiswal PK, Vatanmakarian M, Yousefi H, Sankaralingam S, Alahari SK, Koul S, Koul HK. 2021. Hippo pathway: regulation, deregulation and potential therapeutic targets in cancer. Cancer Lett. 507:112–123. doi:https://doi.org/10.1016/j.canlet.2021.03.006.
- Rosado-Olivieri EA, Anderson K, Kenty JH, Melton DA. 2019. YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing beta cells. Nat Commun. 10(1):1464. doi:https://doi.org/10.1038/s41467-019-09404-6.
- Zhang Y, Ren C, Lu G, Mu Z, Cui W, Gao H, Wang Y. 2014. Anti-diabetic effect of mulberry leaf polysaccharide by inhibiting pancreatic islet cell apoptosis and ameliorating insulin secretory capacity in diabetic rats. Int Immunopharmacol. 22(1):248–257. doi:https://doi.org/10.1016/j.intimp.2014.06.039.
- Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H. 2003. Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection. Diabetes. 52(3):581–587. doi:https://doi.org/10.2337/diabetes.52.3.581.
- Krishnamurthy M, Li J, Fellows GF, Rosenberg L, Goodyer CG, Wang R. 2011. Integrin {alpha}3, but not {beta}1, regulates islet cell survival and function via PI3K/Akt signaling pathways. Endocrinology. 152(2):424–435. doi:https://doi.org/10.1210/en.2010-0877.
- Brizzi MF, Tarone G, Defilippi P. 2012. Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche. Curr Opin Cell Biol. 24(5):645–651. doi:https://doi.org/10.1016/j.ceb.2012.07.001.
- Townsend SE, Gannon M. 2019. Extracellular matrix-associated factors play critical roles in regulating pancreatic beta-cell proliferation and survival. Endocrinology. 160(8):1885–1894. doi:https://doi.org/10.1210/en.2019-00206.
- Zhou Y, Hu Q, Chen F, Zhang J, Guo J, Wang H, Gu J, Ma L, Ho G. 2015. Human umbilical cord matrix-derived stem cells exert trophic effects on beta-cell survival in diabetic rats and isolated islets. Dis Model Mech. 8(12):1625–1633. doi:https://doi.org/10.1242/dmm.021857.
- Li XY, Wu SY, Leung PS. 2019. Human fetal bone marrow-derived mesenchymal stem cells promote the proliferation and differentiation of pancreatic progenitor cells and the engraftment function of Islet-like cell clusters. Int J Mol Sci. 20(17):4083. doi:https://doi.org/10.3390/ijms20174083.
- George M, Ayuso E, Casellas A, Costa C, Devedjian JC, Bosch F. 2002. Beta cell expression of IGF-I leads to recovery from type 1 diabetes. J Clin Invest. 109(9):1153–1163. doi:https://doi.org/10.1172/JCI0212969.
- Zhou X, Chen N, Xu H, Zhou X, Wang J, Fang X, Zhang Y, Li Y, Yang J, Wang X. 2020. Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma. J Hematol Oncol. 13(1):77. doi:https://doi.org/10.1186/s13045-020-00906-1.
- Rigiracciolo DC, Nohata N, Lappano R, Cirillo F, Talia M, Scordamaglia D, Gutkind JS, Maggiolini M. 2020. IGF-1/IGF-1R/FAK/YAP Transduction signaling prompts growth effects in triple-negative breast cancer (TNBC) cells. Cells. 9(4):2619. doi:https://doi.org/10.3390/cells9122619.
- Lomedico P, Rosenthal N, Efstratidadis A, Gilbert W, Kolodner R, Tizard R. 1979. The structure and evolution of the two nonallelic rat preproinsulin genes. Cell. 18(2):545–558. doi:https://doi.org/10.1016/0092-8674(79)90071-0.
- Panciera T, Azzolin L, Cordenonsi M, Piccolo S. 2017. Mechanobiology of YAP and TAZ in physiology and disease. Nat Rev Mol Cell Biol. 18(12):758–770. doi:https://doi.org/10.1038/nrm.2017.87.
- Yu FX, Zhao B, Guan KL. 2015. Hippo Pathway in organ size control, tissue homeostasis, and cancer. Cell. 163(4):811–828. doi:https://doi.org/10.1016/j.cell.2015.10.044.
- Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. 2010. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev. 24(1):72–85. doi:https://doi.org/10.1101/gad.1843810.
- Kim H, Son S, Ko Y, Lee JE, Kim S, Shin I. 2021. YAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERalpha. J Cell Sci. 134(11):1026. doi:https://doi.org/10.1242/jcs.256503.
- Ko JH, Kim YH, Jeong SH, Lee S, Park SN, Shim IK, Kim SC. 2015. Collagen esterification enhances the function and survival of pancreatic beta cells in 2D and 3D culture systems. Biochem Biophys Res Commun. 463(4):1084–1090. doi:https://doi.org/10.1016/j.bbrc.2015.06.062.
- Llacua A, de Haan BJ, Smink SA, de Vos P. 2016. Extracellular matrix components supporting human islet function in alginate-based immunoprotective microcapsules for treatment of diabetes. J Biomed Mater Res A. 104(7):1788–1796. doi:https://doi.org/10.1002/jbm.a.35706.
- Xiao Y, Hill MC, Zhang M, Martin TJ, Morikawa Y, Wang S, Moise AR, Wythe JD, Martin JF. 2018. Hippo signaling plays an essential role in cell state transitions during cardiac fibroblast development. Dev Cell. 45(2):153–169. doi:https://doi.org/10.1016/j.devcel.2018.03.019.
- Korsgren O, Lundgren T, Felldin M, Foss A, Isaksson B, Permert J, Persson NH, Rafael E, Ryden M, Salmela K, Tibell A, Tufveson G, Nilsson B. 2008. Optimising islet engraftment is critical for successful clinical islet transplantation. Diabetologia. 51(2):227–232. doi:https://doi.org/10.1007/s00125-007-0868-9.
- Zhu Y, Chen S, Liu W, Zhang L, Xu F, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T. 2020. Collagens I and V differently regulate the proliferation and adhesion of rat islet INS-1 cells through the integrin beta1/E-cadherin/beta-catenin pathway. Connect Tissue Res. 61:1–13. doi:https://doi.org/10.1080/03008207.2020.1682282.
- Noguchi S, Saito A, Nagase T. 2018. YAP/TAZ signaling as a molecular link between fibrosis and cancer. Int J Mol Sci. 19(11):4352. doi:https://doi.org/10.3390/ijms19113674.
- Hong Y, Park EY, Kim D, Lee H, Jung HS, Jun HS. 2020. Glucosamine potentiates the differentiation of adipose-derived stem cells into glucose-responsive insulin-producing cells. Ann Transl Med. 8(8):561. doi:https://doi.org/10.21037/atm.2020.03.103.
- De Jesus DF, Zhang Z, Kahraman S, Brown NK, Chen M, Hu J, Gupta MK, He C, Kulkarni RN. 2019. m(6)A mRNA methylation regulates human beta-cell biology in physiological states and in Type 2 diabetes. Nat Metab. 1(8):765–774. doi:https://doi.org/10.1038/s42255-019-0089-9.
- Regue L, Zhao L, Ji F, Wang H, Avruch J, Dai N. 2021. RNA m6A reader IMP2/IGF2BP2 promotes pancreatic beta-cell proliferation and insulin secretion by enhancing PDX1 expression. Mol Metab. 48:101209. doi:https://doi.org/10.1016/j.molmet.2021.101209.
- Mamidi A, Prawiro C, Seymour PA, de Lichtenberg KH, Jackson A, Serup P, Semb H. 2018. Mechanosignalling via integrins directs fate decisions of pancreatic progenitors. Nature. 564(7734):114–118. doi:https://doi.org/10.1038/s41586-018-0762-2.
- Galli A, Algerta M, Marciani P, Schulte C, Lenardi C, Milani P, Maffioli E, Tedeschi G, Perego C. 2020. Shaping pancreatic beta-cell differentiation and functioning: the influence of mechanotransduction. Cells. 9(2):413. doi:https://doi.org/10.3390/cells9020413.
- Ardestani A, Maedler K. 2018. The Hippo signaling pathway in pancreatic beta-cells: functions and regulations. Endocr Rev. 39(1):21–35. doi:https://doi.org/10.1210/er.2017-00167.
- Wang X, Freire Valls A, Schermann G, Shen Y, Moya IM, Castro L, Urban S, Solecki GM, Winkler F, Riedemann L, Jain RK, Mazzone M, Schmidt T, Fischer T, Halder G, Ruiz de Almodovar C. 2017. YAP/TAZ orchestrate VEGF signaling during developmental angiogenesis. Dev Cell. 42(5):462–478. doi:https://doi.org/10.1016/j.devcel.2017.08.002.
- Azad T, Janse van Rensburg HJ, Lightbody ED, Neveu B, Champagne A, Ghaffari A, Kay VR, Hao Y, Shen H, Yeung B, Croy BA, Guan KL, Pouliot F, Zhang J, Nicol CJB, Yang X. 2018. A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis. Nat Commun. 9(1):1061. doi:https://doi.org/10.1038/s41467-018-03278-w.
- Fan R, Kim NG, Gumbiner BM. 2013. Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1. Proc Natl Acad Sci U S A. 110(7):2569–2574. doi:https://doi.org/10.1073/pnas.1216462110.
- Xia H, Dai X, Yu H, Zhou S, Fan Z, Wei G, Tang Q, Gong Q, Bi F. 2018. EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy. Cell Death Dis. 9(3):269. doi:https://doi.org/10.1038/s41419-018-0302-x.
- Yuan Z, Kim D, Shu S, Wu J, Guo J, Xiao L, Kaneko S, Coppola D, Cheng JQ. 2016. Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120. J Biol Chem. 291(43):22858. doi:https://doi.org/10.1074/jbc.A109.059675.
- Collak FK, Yagiz K, Luthringer DJ, Erkaya B, Cinar B. 2012. Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1. J Biol Chem. 287(28):23698–23709. doi:https://doi.org/10.1074/jbc.M112.358713.
- Jang SW, Yang SJ, Srinivasan S, Ye K. 2007. Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation. J Biol Chem. 282(42):30836–30844. doi:https://doi.org/10.1074/jbc.M704542200.
- Kim D, Shu S, Coppola MD, Kaneko S, Yuan ZQ, Cheng JQ, Bergmann A. 2010. Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathway. PLoS One. 5(3):9616. doi:https://doi.org/10.1371/journal.pone.0009616.
- Tan JT, Prosser HC, Vanags LZ, Monger SA, Ng MK, Bursill CA. 2014. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1alpha. FASEB J. 28(1):206–217. doi:https://doi.org/10.1096/fj.13-233874.
- Wang Q, Shi W, Zhang Q, Feng W, Wang J, Zhai C, Yan X, Li M. 2020. Inhibition of Siah2 ubiquitin ligase ameliorates monocrotaline-induced pulmonary arterial remodeling through inactivation of YAP. Life Sci. 242:117159. doi:https://doi.org/10.1016/j.lfs.2019.117159.
- Ercin M, Sancar-Bas S, Bolkent S, Gezginci-Oktayoglu S. 2018. Tub and beta-catenin play a key role in insulin and leptin resistance-induced pancreatic beta-cell differentiation. Biochim Biophys Acta Mol Cell Res. 1865(12):1934–1944. doi:https://doi.org/10.1016/j.bbamcr.2018.09.010.
- Johnson MH, de Mejia EG. 2016. Phenolic compounds from fermented berry beverages modulated gene and protein expression to increase insulin secretion from pancreatic beta-cells in vitro. J Agric Food Chem. 64(12):2569–2581. doi:https://doi.org/10.1021/acs.jafc.6b00239.
- Zhu Y, Liu W, Chen S, Xu F, Zhang L, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T. 2021. Collagen type I enhances cell growth and insulin biosynthesis in rat pancreatic cells. J Mol Endocrinol. 67(3):135–148. doi:https://doi.org/10.1530/JME-21-0032.
- Zhu Y, Chen S, Liu W, Zhang L, Xu F, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T. Collagens I and V differently regulate the proliferation and adhesion of rat islet INS-1 cells through the integrin β1/E-cadherin/β-catenin pathway. Connect Tissue Res. 2020;61:1–13.
- Zhao YL, Lu ZY, Zhang X, Liu WW, Yao GD, Liu XL, Liu W, Wu QJ, Hayashi T, Yamato M, Fujisaki H, Hattori S, Atsuzawa Y, Tashiro SI, Onodera S, Ikejima T. 2018. Gelatin promotes cell aggregation and pro-inflammatory cytokine production in PMA-stimulated U937 cells by augmenting endocytosis-autophagy pathway. Int J Biochem Cell Biol. 95:132–142. doi:https://doi.org/10.1016/j.biocel.2018.01.002.
- Kliemt S, Lange C, Otto W, Hintze V, Moller S, Von Bergen M, Hempel U, Kalkhof S. 2013. Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells. J Proteome Res. 12(1):378–389. doi:https://doi.org/10.1021/pr300640h.
- Burgi J, Abrami L, Castanon I, Abriata LA, Kunz B, Yan SE, Lera M, Unger S, Superti-Furga A, Peraro MD, Gaitan MG, van der Goot FG. 2020. Ligand binding to the collagen VI receptor triggers a Talin-to-RhoA switch that regulates receptor endocytosis. Dev Cell. 53(4):418–430. doi:https://doi.org/10.1016/j.devcel.2020.04.015.
- Xiu M, Huan X, Ou Y, Ying S, Wang J. 2021. The basic route of nuclear-targeted transport of IGF-1/IGF-1R and potential biological functions in intestinal epithelial cells. Cell Prolif. 54(6):13030. doi:https://doi.org/10.1111/cpr.13030.
- Crudden C, Song D, Cismas S, Trocme E, Pasca S, Calin GA, Girnita A, Girnita L. 2019. Below the surface: IGF-1R therapeutic targeting and its endocytic journey. Cells. 8(10):316. doi:https://doi.org/10.3390/cells8101223.
- Bergeron JJ, Di Guglielmo GM, Dahan S, Dominguez M, Posner BI. 2016. Spatial and temporal regulation of receptor tyrosine kinase activation and intracellular signal transduction. Annu Rev Biochem. 85:573–597. doi:https://doi.org/10.1146/annurev-biochem-060815-014659.
- Hald J, Galbo T, Rescan C, Radzikowski L, Sprinkel AE, Heimberg H, Ahnfelt-Ronne J, Jensen J, Scharfmann R, Gradwohl G, Kaestner KH, C Stoeckert JNJ Jr., Madsen OD, Madsen OD. 2012. Pancreatic islet and progenitor cell surface markers with cell sorting potential. Diabetologia. 55(1):154–165. doi:https://doi.org/10.1007/s00125-011-2295-1.
- Ma R, Xie X, Zhao L, Wu Y, Wang J. Discoidin domain receptors (DDRs): potential implications in periodontitis. J Cell Physiol. 2021;335.
- Le CC, Bennasroune A, Collin G, Hachet C, Lehrter V, Rioult D, Dedieu S, Morjani H, Appert-Collin A. 2020. LRP-1 promotes colon cancer cell proliferation in 3D Collagen matrices by mediating DDR1 endocytosis. Front Cell Dev Biol. 8:412. doi:https://doi.org/10.3389/fcell.2020.00412.
- Miao L, Zhu S, Wang Y, Li Y, Ding J, Dai J, Cai H, Zhang D, Song Y. 2013. Discoidin domain receptor 1 is associated with poor prognosis of non-small cell lung cancer and promotes cell invasion via epithelial-to-mesenchymal transition. Med Oncol. 30(3):626. doi:https://doi.org/10.1007/s12032-013-0626-4.
- Malaguarnera R, Nicolosi ML, Sacco A, Morcavallo A, Vella V, Voci C, Spatuzza M, Xu SQ, Iozzo RV, Vigneri R, Morrione A, Belfiore A. 2015. Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses. Oncotarget. 6(18):16084–16105. doi:https://doi.org/10.18632/oncotarget.3177.
- Belfiore A, Malaguarnera R, Nicolosi ML, Lappano R, Ragusa M, Morrione A, Vella V. 2018. A novel functional crosstalk between DDR1 and the IGF axis and its relevance for breast cancer. Cell Adh Migr. 12(4):305–314. doi:https://doi.org/10.1080/19336918.2018.1445953.