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Research Article

Mechanics and differential healing outcomes of small and large defect injuries of the tendon-bone attachment in the rat rotator cuff

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Pages 262-273 | Received 24 Feb 2022, Accepted 22 Nov 2022, Published online: 16 Dec 2022

References

  • Matthewson G, Beach CJ, Nelson AA, et al. Partial thickness rotator cuff tears: current concepts. Adv Orthop. 2015;2015:1–11.
  • Randelli PS, Menon A, Nocerino E, et al. Long-term results of arthroscopic rotator cuff repair: initial tear size matters. Am J Sports Med. 2019;47(11):2659–2669. doi:10.1177/0363546519865529.
  • Maman E, Harris C, White L, et al. Outcome of nonoperative treatment of symptomatic rotator cuff tears monitored by magnetic resonance imaging. J Bone Joint Surg Am. 2009;91(8):1898–1906. doi:10.2106/JBJS.G.01335.
  • Kim Y-K, Jung K-H, Kim J-W, et al. Factors affecting rotator cuff integrity after arthroscopic repair for medium-sized or larger cuff tears: a retrospective cohort study. J Shoulder Elbow Surg. 2017;9:108.
  • Reilly P, Amis AA, Wallace AL, Emery RJH. Supraspinatus tears: propagation and strain alteration. J Shoulder Elbow Surg. 2003;12(2):134–138. doi:10.1067/mse.2003.7.
  • Kartus J, Kartus C, Rostgård-Christensen L, et al. Long-term clinical and ultrasound evaluation after arthroscopic acromioplasty in patients with partial rotator cuff tears. Arthrosc: J Arthrosc Relat Surg. 2006;22(1):44–49. doi:10.1016/j.arthro.2005.07.027.
  • Kim HM, Dahiya N, Teefey SA, et al. Relationship of tear size and location to fatty degeneration of the rotator cuff. J Bone Joint Surg Am. 2010;92(4):829–839. doi:10.2106/JBJS.H.01746.
  • Mall NA, Kim HM, Keener JD, et al. Symptomatic progression of asymptomatic rotator cuff tears: a prospective study of clinical and sonographic variables. J Bone Joint Surg Am. 2010;92(16):2623–2633. doi:10.2106/JBJS.I.00506.
  • Tashjian RZ. Epidemiology, natural history, and indications for treatment of rotator cuff tears. Clin Sports Med. 2012;31(4):589–604. doi:10.1016/j.csm.2012.07.001.
  • Moosmayer S, Lund G, Seljom US, et al. Tendon repair compared with physiotherapy in the treatment of rotator cuff tears: a randomized controlled study in 103 cases with a five-year follow-up. J Bone Joint Surg Am. 2014;96(18):1504–1514. doi:10.2106/JBJS.M.01393.
  • Cho NS, Rhee YG. The factors affecting the clinical outcome and integrity of arthroscopically repaired rotator cuff tears of the shoulder. Clin Orthop Surg. 2009;1(2):96. doi:10.4055/cios.2009.1.2.96.
  • Chillemi C, Petrozza V, Garro L, et al. Rotator cuff re-tear or non-healing: histopathological aspects and predictive factors. Knee Surg Sports Traumatol Arthrosc. 2011;19(9):1588–1596. doi:10.1007/s00167-011-1521-1.
  • Hug K, Gerhardt C, Haneveld H, Scheibel M. Arthroscopic knotless-anchor rotator cuff repair: a clinical and radiological evaluation. Knee Surg Sports Traumatol Arthrosc. 2015;23(9):2628–2634. doi:10.1007/s00167-014-3026-1.
  • Kim HM, Caldwell JM, Buza JA, et al. Factors affecting satisfaction and shoulder function in patients with a recurrent rotator cuff tear. J Bone Joint Surg Am. 2014;96(2):106–112. doi:10.2106/JBJS.L.01649.
  • Robinson PM, Wilson J, Dalal S, et al. Rotator cuff repair in patients over 70 years of age: early outcomes and risk factors associated with re-tear. Bone Joint J. 2013;95-B(2):199–205. doi:10.1302/0301-620X.95B2.30246.
  • Soslowsky L, Carpenter JE, DeBano CM, et al. Development and use of an animal model for investigations on rotator cuff disease. J Shoulder Elbow Surg. 1996;5(5):10. doi:10.1016/S1058-2746(96)80070-X.
  • Miller RM, Fujimaki Y, Araki D, et al. Strain distribution due to propagation of tears in the anterior supraspinatus tendon. J Orthop Res. 2014;32(10):1283–1289. doi:10.1002/jor.22675.
  • Miller RM, Thunes J, Musahl V, et al. Effects of tear size and location on predictions of supraspinatus tear propagation. J Biomech. 2018;68:51–57.
  • Locke RC, Peloquin JM, Lemmon EA, et al. Strain distribution of intact rat rotator cuff tendon-to-bone attachments and attachments with defects. J Biomech Eng. 2017;139(11):111007. doi:10.1115/1.4038111.
  • Lemmon EA, Locke RC, Szostek AK, et al. Partial-Width injuries of the rat rotator cuff heal with fibrosis. Connect Tissue Res. 2018;59(5):437–446. doi:10.1080/03008207.2018.1485666.
  • Andarawis-Puri N, Ricchetti ET, Soslowsky LJ. Rotator cuff tendon strain correlates with tear propagation. J Biomech. 2009;42(2):158–163. doi:10.1016/j.jbiomech.2008.10.020.
  • Killian ML, Cavinatto LM, Ward SR, et al. Chronic degeneration leads to poor healing of repaired massive rotator cuff tears in rats. Am J Sports Med. 2015;43(10):2401–2410. doi:10.1177/0363546515596408.
  • Chen M, Shetye SS, Huegel J, et al. Biceps detachment preserves joint function in a chronic massive rotator cuff tear rat model. Am J Sports Med. 2018;46(14):3486–3494. doi:10.1177/0363546518805091.
  • Smietana MJ, Moncada-Larrotiz P, Arruda EM, et al. Tissue-Engineered tendon for enthesis regeneration in a rat rotator cuff model. Biores Open Access. 2017;6(1):47–57. doi:10.1089/biores.2016.0042.
  • Sato EJ, Killian ML, Choi AJ, et al. Skeletal muscle fibrosis and stiffness increase after rotator cuff tendon injury and neuromuscular compromise in a rat model. J Orthop Res. 2014;32(9):1111–1116. doi:10.1002/jor.22646.
  • Thangarajah T, Henshaw F, Sanghani-Kerai A, et al. Supraspinatus detachment causes musculotendinous degeneration and a reduction in bone mineral density at the enthesis in a rat model of chronic rotator cuff degeneration. Shoulder Elbow Surg. 2017;9(3):178–187. doi:10.1177/1758573217696450.
  • Gimbel JA, Van Kleunen JP, Mehta S, et al. Supraspinatus tendon organizational and mechanical properties in a chronic rotator cuff tear animal model. J Biomech. 2004;37(5):739–749. doi:10.1016/j.jbiomech.2003.09.019.
  • Barton ER, Gimbel JA, Williams GR, Soslowsky LJ. Rat supraspinatus muscle atrophy after tendon detachment. J Orthop Res. 2005;23(2):259–265. doi:10.1016/j.orthres.2004.08.018.
  • Yonemitsu R, Tokunaga T, Shukunami C, et al. Fibroblast growth factor 2 enhances tendon-to-bone healing in a rat rotator cuff repair of chronic tears. Am J Sports Med. 2019;47(7):1701–1712. doi:10.1177/0363546519836959.
  • Bell R, Taub P, Cagle P, et al. Development of a mouse model of supraspinatus tendon insertion site healing. J Orthop Res. 2015;33(1):25–32. doi:10.1002/jor.22727.
  • Galatz LM, Sandell LJ, Rothermich SY, et al. Characteristics of the rat supraspinatus tendon during tendon-to-bone healing after acute injury. J Orthop Res. 2006;24(3):541–550. doi:10.1002/jor.20067.
  • Kanazawa T, Gotoh M, Ohta K, et al. Histomorphometric and ultrastructural analysis of the tendon-bone interface after rotator cuff repair in a rat model. Sci Rep. 2016;6(1):33800. doi:10.1038/srep33800.
  • Schwartz AG, Galatz LM, Thomopoulos S. Enthesis regeneration: a role for Gli1+ progenitor cells. Development. 2017;dev.139303. doi:10.1242/dev.139303.
  • Kohler T, Stauber M, Donahue LR, Müller R Automated Compartmental Analysis for High-Throughput Skeletal Phenotyping in Femora of Genetic Mouse Models. Bone. 2007;41:659–667.
  • David MA, Smith MK, Pilachowski RN, et al. Early, focal changes in cartilage cellularity and structure following surgically induced meniscal destabilization in the mouse. J Orthop Res. 2017;35(3):537–547. doi:10.1002/jor.23443.
  • Locke RC, Lemmon EA, Dudzinski E, et al. Photobiomodulation does not influence maturation and mildly improves functional healing of mouse achilles tendons. J Orthop Res. 2020;38(8):1866–1875. doi:10.1002/jor.24592.
  • Lemmon EA, Locke RC, Szostek AK, et al. Partial width injuries of the rat rotator cuff heal with fibrosis. Connect Tissue Res. 2018;59(5). 437–446. doi:10.1080/03008207.2018.1485666.
  • Locke RC, Peloquin JM, Lemmon EA, et al. Strain Distribution of Intact Rat Rotator Cuff Tendon-to-Bone Attachments and Attachments with Defects. J Biomech Eng. 2017;139:111007.
  • Killian ML, Cavinatto L, Shah SA, et al. The effects of chronic unloading and gap formation on tendon-to-bone healing in a rat model of massive rotator cuff tears. J Orthop Res. 2014;32(3):439–447. doi:10.1002/jor.22519.
  • Freedman BR, Rodriguez AB, Leiphart RJ, et al. Dynamic loading and tendon healing affect multiscale tendon properties and ECM stress transmission. Sci Rep. 2018;8(1):10854. doi:10.1038/s41598-018-29060-y.
  • Hillin CD, Fryhofer GW, Freedman BR, et al. Effects of immobilization angle on tendon healing after achilles rupture in a rat model. J Orthop Res. 2019;37(3):562–573. doi:10.1002/jor.24241.
  • Tucker JJ, Riggin CN, Connizzo BK, et al. Effect of overuse-induced tendinopathy on tendon healing in a rat supraspinatus repair model. J Orthop Res. 2016;34(1):161–166. doi:10.1002/jor.22993.
  • Parks AN, McFaline‐figueroa J, Coogan A, et al. Supraspinatus tendon overuse results in degenerative changes to tendon insertion region and adjacent humeral cartilage in a rat model. J Orthop Res. 2017;35(9):1910–1918. doi:10.1002/jor.23496.
  • Kurdziel MD, Davidson A, Ross D, et al. Biomechanical properties of the repaired and non-repaired rat supraspinatus tendon in the acute postoperative period. Connect Tissue Res. 2019;60(3):254–264. doi:10.1080/03008207.2018.1488970.
  • Leek CC, Soulas JM, Sullivan AL, Killian ML. Using tools in mechanobiology to repair tendons. Curr Tissue Microenviron Rep. 2020;1(2):31–40. doi:10.1007/s43152-020-00005-w.
  • Howell K, Chien C, Bell R, et al. Novel model of tendon regeneration reveals distinct cell mechanisms underlying regenerative and fibrotic tendon healing. Sci Rep. 2017;7(1):45238. doi:10.1038/srep45238.
  • Thomopoulos S, Williams GR, Soslowsky LJ. Tendon to bone healing: differences in biomechanical, structural, and compositional properties due to a range of activity levels. J Biomech Eng. 2003;125(1):106–113. doi:10.1115/1.1536660.
  • Sawadkar P, Player D, Bozec L, Mudera V. The mechanobiology of tendon fibroblasts under static and uniaxial cyclic load in a 3D tissue engineered model mimicking native extracellular matrix. J Tissue Eng Regen Med. 2020;14(1):135–146. doi:10.1002/term.2975.
  • Killian ML, Cavinatto L, Galatz LM, Thomopoulos S. The role of mechanobiology in tendon healing. J Shoulder Elbow Surg. 2012;21(2):228–237. doi:10.1016/j.jse.2011.11.002.
  • Beason DP, Kuntz AF, Hsu JE, et al. Development and evaluation of multiple tendon injury models in the mouse. J Biomech. 2012;45(8):1550–1553. doi:10.1016/j.jbiomech.2012.02.022.

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