TGF-ß1 polymorphism determines the progression of joint damage in rheumatoid arthritis

References

• Harris Jr ED. Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 1990;322:1277–89.
   PubMed Web of Science ®Google Scholar
• Sporn MB, Roberts AB, Wakefield LM, de Crombrugghe B. Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Biol 1987;105:1039 — 45.
   Google Scholar
• Raghow R, Postlethwaite AE, Keski-Oja J, Moses HL, Kang AH. Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. J Clin Invest 1987;79:1285–8.
   Google Scholar
• Penttinen RP, Kobayashi S, Bornstein P. Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc Natl Acad Sci USA 1988;85:1105–8.
   Google Scholar
• Rossi P, Karsenty G, Roberts AB, Roche NS, Sporn MB, de Crombrugghe B. A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-beta. Cell 1988;52: 405–14.
   Google Scholar
• Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, et al. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 1986;83:4167–71.
   PubMed Web of Science ®Google Scholar
• Postlethwaite AE, Keski-Oja J, Moses HL, Kang AH. Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. J Exp Med 1987;165:251–6.
   PubMed Web of Science ®Google Scholar
• Yang EY, Moses HL. Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angio-genesis in the chicken chorioallantoic membrane. J Cell Biol 1990;111:731–41.
   PubMed Web of Science ®Google Scholar
• Wahl SM, Hunt DA, Wakefield LM, McCartney-Francis N, Wahl LM, Roberts AB, et al. Transforming growth factor type beta induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci USA 1987;84:5788–92.
   Google Scholar
• Wahl SM, McCartney-Francis N, Mergenhagen SE. Inflam-matory and immunomodulatory roles of TGF-beta. Immunol Today 1989;10:258–61.
   PubMedGoogle Scholar
• Schlaak JF, Pfers I, Meyer Zum Buschenfelde KH, Marker-Hermann E. Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and serone-gative spondylarthropathies. Clin Exp Rheumatol 1996; 14:155–62.
   Google Scholar
• Lafyatis R, Thompson NL, Remmers EF, Flanders KC, Roche NS, Kim SJ, et al. Transforming growth factor-beta production by synovial tissues from rheumatoid patients and streptococcal cell wall arthritic rats. Studies on secretion by synovial fibroblast-like cells and immunohistologic localiza-tion. J Immunol 1989;143:1142–8.
   Google Scholar
• Chu CQ, Field M, Abney E, Zheng RQ, Allard S, Feldmann M, et al. Transforming growth factor-beta 1 in rheumatoid synovial membrane and cartilage/pannus junction. Clin Exp Immunol 1991;86:380–6.
   PubMed Web of Science ®Google Scholar
• Brandes ME, Allen JB, Ogawa Y, Wahl SM. Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals. J Clin Invest 1991;87:1108–13.
   PubMed Web of Science ®Google Scholar
• Fava RA, Olsen NJ, Postlethwaite AE, Broadley KN, Davidson JM, Nanney LB, et al. Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia. J Exp Med 1991;173:1121–32.
   PubMed Web of Science ®Google Scholar
• Allen JB, Manthey CL, Hand AR, Ohura K, Ellingsworth L, Wahl SM. Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta. J Exp Med. 1990;171:231–47.
   PubMed Web of Science ®Google Scholar
• Wahl SM, Allen JB, Costa GL, Wong HL, Dasch JR. Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta. J Exp Med 1993;177:225–30.
   Google Scholar
• Wahl SM. Transforming growth factor beta: the good, the bad, and the ugly. J Exp Med 1994;180:1587–90.
   PubMed Web of Science ®Google Scholar
• Yamada Y, Miyauchi A, Goto J, Takagi Y, Okuizumi H, Kanematsu M, et al. Association of a polymorphism of the transforming growth factor-betal gene with genetic suscept-ibility to osteoporosis in postmenopausal Japanese women. J Bone Miner Res 1998;13:1569–76.
   PubMed Web of Science ®Google Scholar
• Grainger DJ, Heathcote K, Chiano M, Snieder H, Kemp PR, Metcalfe JC, et al. Genetic control of the circulating concentration of transforming growth factor type beta 1. Hum Mol Genet 1999;8:93–7.
   PubMed Web of Science ®Google Scholar
• Ohtsuka T, Yamakage A, Yamazaki S. The polymorphism of transforming growth factor-betal gene in Japanese patients with systemic sclerosis. Br J Dermatol 2002;147:458–63.
   Google Scholar
• Lacha J, Hubacek JA, Viklicky 0, Malek I, Hutchinson I, Vitko S. TGF-beta 1 gene polymorphism is a risk factor for renal dysfunction in heart transplant recipients. Transplant Proc 2001;33: 1567–9.
   Google Scholar
• Schulte CM, Goebell H, Roher HD, Schulte KM. C-509T polymorphism in the TGFB1 gene promoter: impact on Crohn's disease susceptibility and clinical course? Immuno-genetics 2001;53:178–82.
   PubMed Web of Science ®Google Scholar
• Pulleyn LJ, Newton R, Adcock IM, Barnes PJ. TGFbeta 1 allele association with asthma severity. Hum Genet 2001;109:623–7.
   PubMed Web of Science ®Google Scholar
• Sugiura Y, Niimi T, Sato S, Yoshinouchi T, Banno S, Naniwa T, et al. Transforming growth factor betal gene polymorph-ism in rheumatoid arthritis. Ann Rheum Dis 2002;61:826–8.
   PubMed Web of Science ®Google Scholar
• Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315–24.
   PubMed Web of Science ®Google Scholar
• Sharp JT, Young DY, Bluhm GB, Brook A, Brower AC, Corbett M, et al. How many joints in the hands and wrists should be included in a score of radiologic abnormalities used to assess rheumatoid arthritis? Arthritis Rheum 1985;28:1326–35.
   PubMed Web of Science ®Google Scholar
• Yamanishi Y, Firestein GS. Pathogenesis of rheumatoid arthritis: the role of synoviocytes. Rheum Dis Clin North Am 2001;27:355–1.
   PubMed Web of Science ®Google Scholar
• Cheon H, Yu SJ, Yoo DH, Chae IJ, Song GG, Sohn J. Increased expression of pro-inflammatory cytokines and metalloproteinase-1 by TGF-beta 1 in synovial fibroblasts from rheumatoid arthritis and normal individuals. Clin Exp Immunol 2002;127:547–52.
   PubMed Web of Science ®Google Scholar
• Kim SJ, Glick A, Sporn MB, Roberts AB Characterization of the promoter region of the human transforming growth factor-beta 1 gene.: J Biol Chem 1989;264:402–8.
   PubMed Web of Science ®Google Scholar
• Yokota M, Ichihara S, Lin TL, Nakashima N, Yamada Y. Association of a T29-)C polymorphism of the transforming growth factor-betal gene with genetic susceptibility to myocardial infarction in Japanese. Circulation 2000; 101:2783–7.
   Google Scholar
• Karvonen MK, Pesonen U, Koulu M, Niskanen L, Laakso M, Rissanen A, et al. Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels. Nat Med 1998;4:1434–7.
   PubMed Web of Science ®Google Scholar
• Verner K, Schatz G. Protein translocation across membranes. Science 1988;241:1307–13.
   PubMed Web of Science ®Google Scholar
• Syrris P, Carter ND, Metcalfe JC, Kemp PR, Grainger DJ, Kaski JC, et al. Transforming growth factor-beta1 gene polymorphisms and coronary artery disease. Clin Sci (London) 1998;95:659–67.
   PubMed Web of Science ®Google Scholar