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LetterToEditor

Administration of leflunomide to a patient with rheumatoid arthritis on haemodialysis

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Pages 410-411 | Received 16 Nov 2004, Accepted 11 Feb 2005, Published online: 12 Jul 2009

References

  • Beaman J. M., Hackett L. P., Luxton G., Illett K. F. Effect of hemodialysis on leflunomide plasma concentrations. Ann Pharmacother 2002; 36: 75–7
  • Clinical pharmacology/biopharmaceutics review. Leflunomide tablets, Arava; summary basis of approval equivalent. . FDA/CDER Summary Basis of Approval. NDA: 1988; 20–905
  • Strand V., Cohen S., Schiff M., Weaver A., Fleischmann R., Cannon G., et al. Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate. Leflunomide Rheumatoid Arthritis Investigators Group. Arch Intern Med 1999; 159: 2542–50
  • Smolen J. S., Kalden J. R., Scott D. L., Rozman B., Kvien T. K., Larsen A., et al. Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double‐blind, randomised, multicentre trial. European Leflunomide Study Group. Lancet 1999; 353: 259–66

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